Dense transient receptor potential cation channel, vanilloid family, type 2 (TRPV2) immunoreactivity defines a subset of motoneurons in the dorsal lateral nucleus of the spinal cord, the nucleus ambiguus and the trigeminal motor nucleus in rat

Neuroscience

Volumn 151, Issue 1, 2008, Pages 164-173

  Lewinter, R D ^a   Scherrer, G ^a   Basbaum, A I ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

anatomy; capsaicin; nociception; sexual dimorphism; spinal cord; TRP

Indexed keywords

ANDROGEN RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL 2;

AMBIGUUS NUCLEUS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL LABELING; CELL SUBPOPULATION; CONTROLLED STUDY; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; LATERAL GENICULATE BODY; MOTONEURON NUCLEUS; NEUROANATOMY; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; RAT; SPINAL CORD; TRIGEMINAL NUCLEUS;

ANIMALS; BRAIN STEM; CAPSAICIN; CELL COUNT; CELL SIZE; CHOLINE O-ACETYLTRANSFERASE; FEMALE; IMMUNOHISTOCHEMISTRY; MALE; MEDULLA OBLONGATA; MOTOR NEURONS; NOCICEPTORS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ANDROGEN; SEX CHARACTERISTICS; SPINAL CORD; TRIGEMINAL NUCLEUS, SPINAL; TRPV CATION CHANNELS;

EID: 38049058793     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2007.09.073     Document Type: Article

References (38)

1. Atoji Y., Kusindarta D.L., Hamazaki N., and Kaneko A. Innervation of the rat trachea by bilateral cholinergic projections from the N. Ambiguus and direct motor fibers from the cervical spinal cord: a retrograde and anterograde tracer study. Brain Res 1031 (2005) 90-100
2. Barber R.P., Phelps P.E., Houser C.R., Crawford G.D., Salvaterra P.M., and Vaughn J.E. The morphology and distribution of neurons containing choline acetyltransferase in the adult rat spinal cord: an immunocytochemical study. J Comp Neurol 229 (1984) 329-346
3. Barfield R.J., and Geyer L.A. Sexual behavior: ultrasonic postejaculatory song of the male rat. Science 176 (1972) 1349-1350
4. Caterina M.J., Rosen T.A., Tominaga M., Brake A.J., and Julius D. A capsaicin-receptor homologue with a high threshold for noxious heat. Nature 398 (1999) 436-441
5. Caterina M.J., Schumacher M.A., Tominaga M., Rosen T.A., Levine J.D., and Julius D. The capsaicin receptor: a heat-activated ion channel in the pain pathway. Nature 389 (1997) 816-824
6. Cheng S.B., Hayakawa T., Kuchiiwa S., Maeda S., Ito H., Seki M., and Nakagawa S. Evidence for the collateral innervation of the esophagus and the heart from neurons in the compact formation of the N. Ambiguus of the rat. Brain Res 832 (1999) 171-174
7. Cunningham Jr. E.T., and Sawchenko P.E. Dorsal medullary pathways subserving oromotor reflexes in the rat: implications for the central neural control of swallowing. J Comp Neurol 417 (2000) 448-466
8. Fontaine B., Klarsfeld A., Hokfelt T., and Changeux J.P. Calcitonin gene-related peptide, a peptide present in spinal cord motoneurons, increases the number of acetylcholine receptors in primary cultures of chick embryo myotubes. Neurosci Lett 71 (1986) 59-65
9. Freeman L.M., Padgett B.A., Prins G.S., and Breedlove S.M. Distribution of androgen receptor immunoreactivity in the spinal cord of wild-type, androgen-insensitive and gonadectomized male rats. J Neurobiol 27 (1995) 51-59
10. Gacek R.R., and Lyon M.J. Fiber components of the recurrent laryngeal nerve in the cat. Ann Otol Rhinol Laryngol 85 (1976) 460-471
11. Gaudet A.D., Williams S.J., Hwi L.P., and Ramer M.S. Regulation of TRPV2 by axotomy in sympathetic, but not sensory neurons. Brain Res 1017 (2004) 155-162
12. Goldstein L.A., and Sengelaub D.R. Motoneuron morphology in the dorsolateral nucleus of the rat spinal cord: Normal development and androgenic regulation. J Comp Neurol 338 (1993) 588-600
13. Gottlieb S., Taylor A., and Bosley M.A. The distribution of afferent neurones in the mesencephalic nucleus of the fifth nerve in the cat. J Comp Neurol 228 (1984) 273-283
14. Ichikawa H., Fukunaga T., Jin H.W., Fujita M., Takano-Yamamoto T., and Sugimoto T. VR1-, VRL-1- and P2X3 receptor-immunoreactive innervation of the rat temporomandibular joint. Brain Res 1008 (2004) 131-136
15. Jordan C. Androgen receptor (AR) immunoreactivity in rat pudendal motoneurons: implications for accessory proteins. Horm Behav 32 (1997) 1-10
16. Jordan C.L., Breedlove S.M., and Arnold A.P. Sexual dimorphism and the influence of neonatal androgen in the dorsolateral motor nucleus of the rat lumbar spinal cord. Brain Res 249 (1982) 309-314
17. Jordan C.L., Padgett B., Hershey J., Prins G., and Arnold A. Ontogeny of androgen receptor immunoreactivity in lumbar motoneurons and in the sexually dimorphic levator ani muscle of male rats. J Comp Neurol 379 (1997) 88-98
18. Kanzaki M., Zhang Y.Q., Mashima H., Li L., Shibata H., and Kojima I. Translocation of a calcium-permeable cation channel induced by insulin-like growth factor-I. Nat Cell Biol 1 (1999) 165-170
19. Kashiba H., Uchida Y., Takeda D., Nishigori A., Ueda Y., Kuribayashi K., and Ohshima M. TRPV2-immunoreactive intrinsic neurons in the rat intestine. Neurosci Lett 366 (2004) 193-196
20. Kolta A. In vitro investigation of synaptic relations between interneurons surrounding the trigeminal motor nucleus and masseteric motoneurons. J Neurophysiol 78 (1997) 1720-1725
21. Lassmann G. [Muscle spindles and sensory nerve endings in the urethral sphincter]. Acta Neuropathol (Berl) 63 (1984) 344-346
22. Leong S.K., and Ling E.A. Labelling neurons with fluorescent dyes administered via intravenous, subcutaneous or intraperitoneal route. J Neurosci Methods 32 (1990) 15-23
23. Lewinter R.D., Skinner K., Julius D., and Basbaum A.I. Immunoreactive TRPV-2 (VRL-1), a capsaicin receptor homolog, in the spinal cord of the rat. J Comp Neurol 470 (2004) 400-408
24. Llewellyn-Smith I.J., Pilowsky P., and Minson J.B. The tungstate-stabilized tetramethylbenzidine reaction for light and electron microscopic immunocytochemistry and for revealing biocytin-filled neurons. J Neurosci Methods 46 (1993) 27-40
25. Ma Q.P. Vanilloid receptor homologue, VRL1, is expressed by both A- and C-fiber sensory neurons. Neuroreport 12 (2001) 3693-3695
26. McKenna K.E., and Nadelhaft I. The organization of the pudendal nerve in the male and female rat. J Comp Neurol 248 (1986) 532-549
27. New H.V., and Mudge A.W. Calcitonin gene-related peptide regulates muscle acetylcholine receptor synthesis. Nature 323 (1986) 809-811
28. Schroder H.D. Organization of the motoneurons innervating the pelvic muscles of the male rat. J Comp Neurol 192 (1980) 567-587
29. Sengelaub D.R., and Arnold A.P. Hormonal control of neuron number in sexually dimorphic spinal nuclei of the rag: I. Testosterone-regulated death in the dorsolateral nucleus. J Comp Neurol 280 (1989) 622-629
30. Shigenaga Y., Yoshida A., Tsuru K., Mitsuhiro Y., Otani K., and Cao C.Q. Physiological and morphological characteristics of cat masticatory motoneurons-intracellular injection of HRP. Brain Res 461 (1988) 238-256
31. Takanaga A., Hayakawa T., Tanaka K., Kawabata K., Maeda S., and Seki M. Immunohistochemical characterization of cardiac vagal preganglionic neurons in the rat. Auton Neurosci 106 (2003) 132-137
32. Tominaga M., Caterina M.J., Malmberg A.B., Rosen T.A., Gilbert H., Skinner K., Raumann B.E., Basbaum A.I., and Julius D. The cloned capsaicin receptor integrates multiple pain-producing stimuli. Neuron 21 (1998) 531-543
33. Tribollet E., Barberis C., and Arsenijevic Y. Distribution of vasopressin and oxytocin receptors in the rat spinal cord: sex-related differences and effect of castration in pudendal motor nuclei. Neuroscience 78 (1997) 499-509
34. Van der A.F., Roskams T., Blyweert W., Ost D., Bogaert G., and De Ridder D. Identification of kit positive cells in the human urinary tract. J Urol 171 (2004) 2492-2496
35. Wainwright A., Rutter A.R., Seabrook G.R., Reilly K., and Oliver K.R. Discrete expression of TRPV2 within the hypothalamo-neurohypophysial system: Implications for regulatory activity within the hypothalamic-pituitary-adrenal axis. J Comp Neurol 474 (2004) 24-42
36. Ward O.B., Wexler A.M., Carlucci J.R., Eckert M.A., and Ward I.L. Critical periods of sensitivity of sexually dimorphic spinal nuclei to prenatal testosterone exposure in female rats. Horm Behav 30 (1996) 407-415
37. Woodbury C.J., Zwick M., Wang S., Lawson J.J., Caterina M.J., Koltzenburg M., Albers K.M., Koerber H.R., and Davis B.M. Nociceptors lacking TRPV1 and TRPV2 have normal heat responses. J Neurosci 24 (2004) 6410-6415
38. Yu W.H., and McGinnis M.Y. Androgen receptors in cranial nerve motor nuclei of male and female rats. J Neurobiol 46 (2001) 1-10