메뉴 건너뛰기




Volumn 17, Issue 2, 2009, Pages 244-251

Vanilloid receptor TRPV1-mediated phosphorylation of ERK in murine adjuvant arthritis

Author keywords

Allodynia; Complete Freund's adjuvant (CFA); Dorsal root ganglia (DRG); Extracellularly regulated kinase (ERK); Hyperalgesia; MAPK; Mouse; Osteoarthritis; Transient receptor potential vanilloid 1 (TRPV1)

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; VANILLOID RECEPTOR 1;

EID: 59249097735     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2008.06.015     Document Type: Article
Times cited : (37)

References (64)
  • 2
    • 0032967640 scopus 로고    scopus 로고
    • Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites
    • Guo A., Vulchanova L., Wang J., Li X., and Elde R. Immunocytochemical localization of the vanilloid receptor 1 (VR1): relationship to neuropeptides, the P2X3 purinoceptor and IB4 binding sites. Eur J Neurosci 11 (1999) 946-958
    • (1999) Eur J Neurosci , vol.11 , pp. 946-958
    • Guo, A.1    Vulchanova, L.2    Wang, J.3    Li, X.4    Elde, R.5
  • 4
    • 0034954583 scopus 로고    scopus 로고
    • VR1 protein expression increases in undamaged DRG neurons after partial nerve injury
    • Hudson L.J., Bevan S., Wotherspoon G., Gentry C., Fox A., and Winter J. VR1 protein expression increases in undamaged DRG neurons after partial nerve injury. Eur J Neurosci 13 (2001) 2105-2114
    • (2001) Eur J Neurosci , vol.13 , pp. 2105-2114
    • Hudson, L.J.1    Bevan, S.2    Wotherspoon, G.3    Gentry, C.4    Fox, A.5    Winter, J.6
  • 5
    • 1342310146 scopus 로고    scopus 로고
    • Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling
    • Robinson D.R., McNaughton P.A., Evans M.L., and Hicks G.A. Characterization of the primary spinal afferent innervation of the mouse colon using retrograde labelling. Neurogastroenterol Motil 16 (2004) 113-124
    • (2004) Neurogastroenterol Motil , vol.16 , pp. 113-124
    • Robinson, D.R.1    McNaughton, P.A.2    Evans, M.L.3    Hicks, G.A.4
  • 6
    • 0041691167 scopus 로고    scopus 로고
    • Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract
    • Ward S.M., Bayguinov J., Won K.J., Grundy D., and Berthoud H.R. Distribution of the vanilloid receptor (VR1) in the gastrointestinal tract. J Comp Neurol 465 (2003) 121-135
    • (2003) J Comp Neurol , vol.465 , pp. 121-135
    • Ward, S.M.1    Bayguinov, J.2    Won, K.J.3    Grundy, D.4    Berthoud, H.R.5
  • 7
    • 1842815234 scopus 로고    scopus 로고
    • VR1-, VRL-1- and P2X3 receptor-immunoreactive innervation of the rat temporomandibular joint
    • Ichikawa H., Fukunaga T., Jin H.W., Fujita M., Takano-Yamamoto T., and Sugimoto T. VR1-, VRL-1- and P2X3 receptor-immunoreactive innervation of the rat temporomandibular joint. Brain Res 1008 (2004) 131-136
    • (2004) Brain Res , vol.1008 , pp. 131-136
    • Ichikawa, H.1    Fukunaga, T.2    Jin, H.W.3    Fujita, M.4    Takano-Yamamoto, T.5    Sugimoto, T.6
  • 9
    • 23944442240 scopus 로고    scopus 로고
    • Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis
    • Fernihough J., Gentry C., Bevan S., and Winter J. Regulation of calcitonin gene-related peptide and TRPV1 in a rat model of osteoarthritis. Neurosci Lett 388 (2005) 75-80
    • (2005) Neurosci Lett , vol.388 , pp. 75-80
    • Fernihough, J.1    Gentry, C.2    Bevan, S.3    Winter, J.4
  • 10
    • 45849102714 scopus 로고    scopus 로고
    • Vanilloid receptor TRPV1-positive sensory afferents in the mouse ankle and knee joints
    • Cho W.G., and Valtschanoff J.G. Vanilloid receptor TRPV1-positive sensory afferents in the mouse ankle and knee joints. Brain Res 1219 (2008) 59-65
    • (2008) Brain Res , vol.1219 , pp. 59-65
    • Cho, W.G.1    Valtschanoff, J.G.2
  • 11
    • 34250755449 scopus 로고    scopus 로고
    • Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis
    • Engler A., Aeschlimann A., Simmen B.R., Michel B.A., Gay R.E., Gay S., et al. Expression of transient receptor potential vanilloid 1 (TRPV1) in synovial fibroblasts from patients with osteoarthritis and rheumatoid arthritis. Biochem Biophys Res Commun 359 (2007) 884-888
    • (2007) Biochem Biophys Res Commun , vol.359 , pp. 884-888
    • Engler, A.1    Aeschlimann, A.2    Simmen, B.R.3    Michel, B.A.4    Gay, R.E.5    Gay, S.6
  • 12
    • 33748418461 scopus 로고    scopus 로고
    • Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes
    • Kochukov M.Y., McNearney T.A., Fu Y., and Westlund K.N. Thermosensitive TRP ion channels mediate cytosolic calcium response in human synoviocytes. Am J Physiol Cell Physiol 291 (2006) C424-C432
    • (2006) Am J Physiol Cell Physiol , vol.291
    • Kochukov, M.Y.1    McNearney, T.A.2    Fu, Y.3    Westlund, K.N.4
  • 13
    • 0025871477 scopus 로고
    • Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons
    • Holzer P. Capsaicin: cellular targets, mechanisms of action, and selectivity for thin sensory neurons. Pharmacol Rev 43 (1991) 143-201
    • (1991) Pharmacol Rev , vol.43 , pp. 143-201
    • Holzer, P.1
  • 14
    • 0036303675 scopus 로고    scopus 로고
    • Vanilloid (capsaicin) receptors in health and disease
    • Szallasi A. Vanilloid (capsaicin) receptors in health and disease. Am J Clin Pathol 118 (2002) 110-121
    • (2002) Am J Clin Pathol , vol.118 , pp. 110-121
    • Szallasi, A.1
  • 15
    • 3843090895 scopus 로고    scopus 로고
    • Capsaicin-induced joint inflammation is not blocked by local anesthesia
    • Tang M.L., Haas D.A., and Hu J.W. Capsaicin-induced joint inflammation is not blocked by local anesthesia. Anesth Prog 51 (2004) 2-9
    • (2004) Anesth Prog , vol.51 , pp. 2-9
    • Tang, M.L.1    Haas, D.A.2    Hu, J.W.3
  • 16
    • 2342555611 scopus 로고    scopus 로고
    • Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a Freund's adjuvant-induced chronic arthritis model in the rat
    • Helyes Z., Szabo A., Nemeth J., Jakab B., Pinter E., Banvolgyi A., et al. Antiinflammatory and analgesic effects of somatostatin released from capsaicin-sensitive sensory nerve terminals in a Freund's adjuvant-induced chronic arthritis model in the rat. Arthritis Rheum 50 (2004) 1677-1685
    • (2004) Arthritis Rheum , vol.50 , pp. 1677-1685
    • Helyes, Z.1    Szabo, A.2    Nemeth, J.3    Jakab, B.4    Pinter, E.5    Banvolgyi, A.6
  • 17
    • 25844464116 scopus 로고    scopus 로고
    • Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice
    • Bolcskei K., Helyes Z., Szabo A., Sandor K., Elekes K., Nemeth J., et al. Investigation of the role of TRPV1 receptors in acute and chronic nociceptive processes using gene-deficient mice. Pain 117 (2005) 368-376
    • (2005) Pain , vol.117 , pp. 368-376
    • Bolcskei, K.1    Helyes, Z.2    Szabo, A.3    Sandor, K.4    Elekes, K.5    Nemeth, J.6
  • 19
    • 17844380256 scopus 로고    scopus 로고
    • The role of substance P in microvascular responses in murine joint inflammation
    • Keeble J., Blades M., Pitzalis C., Castro da Rocha F.A., and Brain S.D. The role of substance P in microvascular responses in murine joint inflammation. Br J Pharmacol 144 (2005) 1059-1066
    • (2005) Br J Pharmacol , vol.144 , pp. 1059-1066
    • Keeble, J.1    Blades, M.2    Pitzalis, C.3    Castro da Rocha, F.A.4    Brain, S.D.5
  • 20
    • 23044501630 scopus 로고    scopus 로고
    • Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice
    • Szabo A., Helyes Z., Sandor K., Bite A., Pinter E., Nemeth J., et al. Role of transient receptor potential vanilloid 1 receptors in adjuvant-induced chronic arthritis: in vivo study using gene-deficient mice. J Pharmacol Exp Ther 314 (2005) 111-119
    • (2005) J Pharmacol Exp Ther , vol.314 , pp. 111-119
    • Szabo, A.1    Helyes, Z.2    Sandor, K.3    Bite, A.4    Pinter, E.5    Nemeth, J.6
  • 21
    • 33646430343 scopus 로고    scopus 로고
    • Capsaicin-induced vasoconstriction in the mouse knee joint: a study using TRPV1 knockout mice
    • Keeble J.E., and Brain S.D. Capsaicin-induced vasoconstriction in the mouse knee joint: a study using TRPV1 knockout mice. Neurosci Lett 401 (2006) 55-58
    • (2006) Neurosci Lett , vol.401 , pp. 55-58
    • Keeble, J.E.1    Brain, S.D.2
  • 22
    • 0029011218 scopus 로고
    • The MAPK signaling cascade
    • Seger R., and Krebs E.G. The MAPK signaling cascade. Faseb J 9 (1995) 726-735
    • (1995) Faseb J , vol.9 , pp. 726-735
    • Seger, R.1    Krebs, E.G.2
  • 23
    • 0034517388 scopus 로고    scopus 로고
    • Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry
    • Lewis T.S., Hunt J.B., Aveline L.D., Jonscher K.R., Louie D.F., Yeh J.M., et al. Identification of novel MAP kinase pathway signaling targets by functional proteomics and mass spectrometry. Mol Cell 6 (2000) 1343-1354
    • (2000) Mol Cell , vol.6 , pp. 1343-1354
    • Lewis, T.S.1    Hunt, J.B.2    Aveline, L.D.3    Jonscher, K.R.4    Louie, D.F.5    Yeh, J.M.6
  • 24
    • 7044274054 scopus 로고    scopus 로고
    • Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs
    • Karin M. Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugs. Ann Rheum Dis 63 Suppl 2 (2004) ii62-ii64
    • (2004) Ann Rheum Dis , vol.63 , Issue.SUPPL. 2
    • Karin, M.1
  • 25
    • 35348923750 scopus 로고    scopus 로고
    • Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms
    • Thiel M.J., Schaefer C.J., Lesch M.E., Mobley J.L., Dudley D.T., Tecle H., et al. Central role of the MEK/ERK MAP kinase pathway in a mouse model of rheumatoid arthritis: potential proinflammatory mechanisms. Arthritis Rheum 56 (2007) 3347-3357
    • (2007) Arthritis Rheum , vol.56 , pp. 3347-3357
    • Thiel, M.J.1    Schaefer, C.J.2    Lesch, M.E.3    Mobley, J.L.4    Dudley, D.T.5    Tecle, H.6
  • 26
    • 2342441834 scopus 로고    scopus 로고
    • Mitogen-activated protein kinases as potential targets for pain killers
    • Ji R.R. Mitogen-activated protein kinases as potential targets for pain killers. Curr Opin Investig Drugs 5 (2004) 71-75
    • (2004) Curr Opin Investig Drugs , vol.5 , pp. 71-75
    • Ji, R.R.1
  • 27
    • 0043021910 scopus 로고    scopus 로고
    • Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain
    • Galan A., Cervero F., and Laird J.M. Extracellular signaling-regulated kinase-1 and -2 (ERK 1/2) mediate referred hyperalgesia in a murine model of visceral pain. Brain Res Mol Brain Res 116 (2003) 126-134
    • (2003) Brain Res Mol Brain Res , vol.116 , pp. 126-134
    • Galan, A.1    Cervero, F.2    Laird, J.M.3
  • 28
    • 0042267829 scopus 로고    scopus 로고
    • Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia
    • Svensson C.I., Hua X.Y., Protter A.A., Powell H.C., and Yaksh T.L. Spinal p38 MAP kinase is necessary for NMDA-induced spinal PGE(2) release and thermal hyperalgesia. Neuroreport 14 (2003) 1153-1157
    • (2003) Neuroreport , vol.14 , pp. 1153-1157
    • Svensson, C.I.1    Hua, X.Y.2    Protter, A.A.3    Powell, H.C.4    Yaksh, T.L.5
  • 29
    • 0037705314 scopus 로고    scopus 로고
    • p38 Mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • Jin S.X., Zhuang Z.Y., Woolf C.J., and Ji R.R. p38 Mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain. J Neurosci 23 (2003) 4017-4022
    • (2003) J Neurosci , vol.23 , pp. 4017-4022
    • Jin, S.X.1    Zhuang, Z.Y.2    Woolf, C.J.3    Ji, R.R.4
  • 30
    • 0037179755 scopus 로고    scopus 로고
    • p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia
    • Ji R.R., Samad T.A., Jin S.X., Schmoll R., and Woolf C.J. p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPV1 levels and maintains heat hyperalgesia. Neuron 36 (2002) 57-68
    • (2002) Neuron , vol.36 , pp. 57-68
    • Ji, R.R.1    Samad, T.A.2    Jin, S.X.3    Schmoll, R.4    Woolf, C.J.5
  • 31
    • 2442476610 scopus 로고    scopus 로고
    • Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model
    • Sweitzer S.M., Medicherla S., Almirez R., Dugar S., Chakravarty S., Shumilla J.A., et al. Antinociceptive action of a p38alpha MAPK inhibitor, SD-282, in a diabetic neuropathy model. Pain 109 (2004) 409-419
    • (2004) Pain , vol.109 , pp. 409-419
    • Sweitzer, S.M.1    Medicherla, S.2    Almirez, R.3    Dugar, S.4    Chakravarty, S.5    Shumilla, J.A.6
  • 32
    • 33750527107 scopus 로고    scopus 로고
    • Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons
    • Firner M., Greffrath W., and Treede R.D. Phosphorylation of extracellular signal-related protein kinase is required for rapid facilitation of heat-induced currents in rat dorsal root ganglion neurons. Neuroscience 143 (2006) 253-263
    • (2006) Neuroscience , vol.143 , pp. 253-263
    • Firner, M.1    Greffrath, W.2    Treede, R.D.3
  • 33
    • 35448963034 scopus 로고    scopus 로고
    • The cytokine TNFalpha increases the proportion of DRG neurones expressing the TRPV1 receptor via the TNFR1 receptor and ERK activation
    • Hensellek S., Brell P., Schaible H.G., Brauer R., and Segond von Banchet G. The cytokine TNFalpha increases the proportion of DRG neurones expressing the TRPV1 receptor via the TNFR1 receptor and ERK activation. Mol Cell Neurosci 36 (2007) 381-391
    • (2007) Mol Cell Neurosci , vol.36 , pp. 381-391
    • Hensellek, S.1    Brell, P.2    Schaible, H.G.3    Brauer, R.4    Segond von Banchet, G.5
  • 34
    • 21844449963 scopus 로고    scopus 로고
    • Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats
    • Cruz C.D., Neto F.L., Castro-Lopes J., McMahon S.B., and Cruz F. Inhibition of ERK phosphorylation decreases nociceptive behaviour in monoarthritic rats. Pain 116 (2005) 411-419
    • (2005) Pain , vol.116 , pp. 411-419
    • Cruz, C.D.1    Neto, F.L.2    Castro-Lopes, J.3    McMahon, S.B.4    Cruz, F.5
  • 35
    • 33744511186 scopus 로고    scopus 로고
    • The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint
    • Seino D., Tokunaga A., Tachibana T., Yoshiya S., Dai Y., Obata K., et al. The role of ERK signaling and the P2X receptor on mechanical pain evoked by movement of inflamed knee joint. Pain 123 (2006) 193-203
    • (2006) Pain , vol.123 , pp. 193-203
    • Seino, D.1    Tokunaga, A.2    Tachibana, T.3    Yoshiya, S.4    Dai, Y.5    Obata, K.6
  • 36
    • 33750322263 scopus 로고    scopus 로고
    • The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis
    • Fusello A.M., Mandik-Nayak L., Shih F., Lewis R.E., Allen P.M., and Shaw A.S. The MAPK scaffold kinase suppressor of Ras is involved in ERK activation by stress and proinflammatory cytokines and induction of arthritis. J Immunol 177 (2006) 6152-6158
    • (2006) J Immunol , vol.177 , pp. 6152-6158
    • Fusello, A.M.1    Mandik-Nayak, L.2    Shih, F.3    Lewis, R.E.4    Allen, P.M.5    Shaw, A.S.6
  • 37
    • 33846175113 scopus 로고    scopus 로고
    • FR180204, a novel and selective inhibitor of extracellular signal-regulated kinase, ameliorates collagen-induced arthritis in mice
    • Ohori M., Takeuchi M., Maruki R., Nakajima H., and Miyake H. FR180204, a novel and selective inhibitor of extracellular signal-regulated kinase, ameliorates collagen-induced arthritis in mice. Naunyn Schmiedebergs Arch Pharmacol 374 (2007) 311-316
    • (2007) Naunyn Schmiedebergs Arch Pharmacol , vol.374 , pp. 311-316
    • Ohori, M.1    Takeuchi, M.2    Maruki, R.3    Nakajima, H.4    Miyake, H.5
  • 39
    • 0023924046 scopus 로고
    • A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia
    • Hargreaves K., Dubner R., Brown F., Flores C., and Joris J. A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia. Pain 32 (1988) 77-88
    • (1988) Pain , vol.32 , pp. 77-88
    • Hargreaves, K.1    Dubner, R.2    Brown, F.3    Flores, C.4    Joris, J.5
  • 40
    • 0019512029 scopus 로고
    • Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates
    • Wooley P.H., Luthra H.S., Stuart J.M., and David C.S. Type II collagen-induced arthritis in mice. I. Major histocompatibility complex (I region) linkage and antibody correlates. J Exp Med 154 (1981) 688-700
    • (1981) J Exp Med , vol.154 , pp. 688-700
    • Wooley, P.H.1    Luthra, H.S.2    Stuart, J.M.3    David, C.S.4
  • 41
    • 0034737002 scopus 로고    scopus 로고
    • On the problem of lamination in the superficial dorsal horn of mammals: a reappraisal of the substantia gelatinosa in postnatal life
    • Woodbury C.J., Ritter A.M., and Koerber H.R. On the problem of lamination in the superficial dorsal horn of mammals: a reappraisal of the substantia gelatinosa in postnatal life. J Comp Neurol 417 (2000) 88-102
    • (2000) J Comp Neurol , vol.417 , pp. 88-102
    • Woodbury, C.J.1    Ritter, A.M.2    Koerber, H.R.3
  • 43
    • 85047690839 scopus 로고    scopus 로고
    • Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control
    • Karai L., Brown D.C., Mannes A.J., Connelly S.T., Brown J., Gandal M., et al. Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control. J Clin Invest 113 (2004) 1344-1352
    • (2004) J Clin Invest , vol.113 , pp. 1344-1352
    • Karai, L.1    Brown, D.C.2    Mannes, A.J.3    Connelly, S.T.4    Brown, J.5    Gandal, M.6
  • 44
    • 0034636441 scopus 로고    scopus 로고
    • Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia
    • Davis J.B., Gray J., Gunthorpe M.J., Hatcher J.P., Davey P.T., Overend P., et al. Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia. Nature 405 (2000) 183-187
    • (2000) Nature , vol.405 , pp. 183-187
    • Davis, J.B.1    Gray, J.2    Gunthorpe, M.J.3    Hatcher, J.P.4    Davey, P.T.5    Overend, P.6
  • 45
    • 0037215646 scopus 로고    scopus 로고
    • The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain
    • Walker K.M., Urban L., Medhurst S.J., Patel S., Panesar M., Fox A.J., et al. The VR1 antagonist capsazepine reverses mechanical hyperalgesia in models of inflammatory and neuropathic pain. J Pharmacol Exp Ther 304 (2003) 56-62
    • (2003) J Pharmacol Exp Ther , vol.304 , pp. 56-62
    • Walker, K.M.1    Urban, L.2    Medhurst, S.J.3    Patel, S.4    Panesar, M.5    Fox, A.J.6
  • 46
    • 33847272525 scopus 로고    scopus 로고
    • In vivo osteoarthritis target validation utilizing genetically-modified mice
    • Glasson S.S. In vivo osteoarthritis target validation utilizing genetically-modified mice. Curr Drug Targets 8 (2007) 367-376
    • (2007) Curr Drug Targets , vol.8 , pp. 367-376
    • Glasson, S.S.1
  • 47
    • 33746356883 scopus 로고    scopus 로고
    • Joint mobilization reduces hyperalgesia associated with chronic muscle and joint inflammation in rats
    • Sluka K.A., Skyba D.A., Radhakrishnan R., Leeper B.J., and Wright A. Joint mobilization reduces hyperalgesia associated with chronic muscle and joint inflammation in rats. J Pain 7 (2006) 602-607
    • (2006) J Pain , vol.7 , pp. 602-607
    • Sluka, K.A.1    Skyba, D.A.2    Radhakrishnan, R.3    Leeper, B.J.4    Wright, A.5
  • 48
    • 59249099699 scopus 로고    scopus 로고
    • Vanilloid receptor TRPV1-mediated phosphorylation of MAPK in a mouse model of osteoarthritis
    • Chen Y., Willcockson H.H., and Valtschanoff J.G. Vanilloid receptor TRPV1-mediated phosphorylation of MAPK in a mouse model of osteoarthritis. Soc Neurosci Abst 33 (2007) 22
    • (2007) Soc Neurosci Abst , vol.33 , pp. 22
    • Chen, Y.1    Willcockson, H.H.2    Valtschanoff, J.G.3
  • 49
    • 0037192438 scopus 로고    scopus 로고
    • Activation of spinal extracellular signaling-regulated kinase-1 and -2 by intraplantar carrageenan in rodents
    • Galan A., Lopez-Garcia J.A., Cervero F., and Laird J.M. Activation of spinal extracellular signaling-regulated kinase-1 and -2 by intraplantar carrageenan in rodents. Neurosci Lett 322 (2002) 37-40
    • (2002) Neurosci Lett , vol.322 , pp. 37-40
    • Galan, A.1    Lopez-Garcia, J.A.2    Cervero, F.3    Laird, J.M.4
  • 50
    • 4644312225 scopus 로고    scopus 로고
    • Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization
    • Kawasaki Y., Kohno T., Zhuang Z.Y., Brenner G.J., Wang H., Van Der Meer C., et al. Ionotropic and metabotropic receptors, protein kinase A, protein kinase C, and Src contribute to C-fiber-induced ERK activation and cAMP response element-binding protein phosphorylation in dorsal horn neurons, leading to central sensitization. J Neurosci 24 (2004) 8310-8321
    • (2004) J Neurosci , vol.24 , pp. 8310-8321
    • Kawasaki, Y.1    Kohno, T.2    Zhuang, Z.Y.3    Brenner, G.J.4    Wang, H.5    Van Der Meer, C.6
  • 51
    • 0242573273 scopus 로고    scopus 로고
    • The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1
    • Krapivinsky G., Krapivinsky L., Manasian Y., Ivanov A., Tyzio R., Pellegrino C., et al. The NMDA receptor is coupled to the ERK pathway by a direct interaction between NR2B and RasGRF1. Neuron 40 (2003) 775-784
    • (2003) Neuron , vol.40 , pp. 775-784
    • Krapivinsky, G.1    Krapivinsky, L.2    Manasian, Y.3    Ivanov, A.4    Tyzio, R.5    Pellegrino, C.6
  • 52
    • 0037080003 scopus 로고    scopus 로고
    • ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity
    • Ji R.R., Befort K., Brenner G.J., and Woolf C.J. ERK MAP kinase activation in superficial spinal cord neurons induces prodynorphin and NK-1 upregulation and contributes to persistent inflammatory pain hypersensitivity. J Neurosci 22 (2002) 478-485
    • (2002) J Neurosci , vol.22 , pp. 478-485
    • Ji, R.R.1    Befort, K.2    Brenner, G.J.3    Woolf, C.J.4
  • 53
    • 0035166616 scopus 로고    scopus 로고
    • The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory
    • Sweatt J.D. The neuronal MAP kinase cascade: a biochemical signal integration system subserving synaptic plasticity and memory. J Neurochem 76 (2001) 1-10
    • (2001) J Neurochem , vol.76 , pp. 1-10
    • Sweatt, J.D.1
  • 54
    • 4143075943 scopus 로고    scopus 로고
    • VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus
    • Li D.P., Chen S.R., and Pan H.L. VR1 receptor activation induces glutamate release and postsynaptic firing in the paraventricular nucleus. J Neurophysiol 92 (2004) 1807-1816
    • (2004) J Neurophysiol , vol.92 , pp. 1807-1816
    • Li, D.P.1    Chen, S.R.2    Pan, H.L.3
  • 55
    • 15244354399 scopus 로고    scopus 로고
    • Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation
    • Schicho R., Donnerer J., Liebmann I., and Lippe I.T. Nociceptive transmitter release in the dorsal spinal cord by capsaicin-sensitive fibers after noxious gastric stimulation. Brain Res 1039 (2005) 108-115
    • (2005) Brain Res , vol.1039 , pp. 108-115
    • Schicho, R.1    Donnerer, J.2    Liebmann, I.3    Lippe, I.T.4
  • 56
    • 32544449280 scopus 로고    scopus 로고
    • Calcium calmodulin-stimulated adenylyl cyclases contribute to activation of extracellular signal-regulated kinase in spinal dorsal horn neurons in adult rats and mice
    • Wei F., Vadakkan K.I., Toyoda H., Wu L.J., Zhao M.G., Xu H., et al. Calcium calmodulin-stimulated adenylyl cyclases contribute to activation of extracellular signal-regulated kinase in spinal dorsal horn neurons in adult rats and mice. J Neurosci 26 (2006) 851-861
    • (2006) J Neurosci , vol.26 , pp. 851-861
    • Wei, F.1    Vadakkan, K.I.2    Toyoda, H.3    Wu, L.J.4    Zhao, M.G.5    Xu, H.6
  • 57
    • 17044399313 scopus 로고    scopus 로고
    • Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse
    • Breese N.M., George A.C., Pauers L.E., and Stucky C.L. Peripheral inflammation selectively increases TRPV1 function in IB4-positive sensory neurons from adult mouse. Pain 115 (2005) 37-49
    • (2005) Pain , vol.115 , pp. 37-49
    • Breese, N.M.1    George, A.C.2    Pauers, L.E.3    Stucky, C.L.4
  • 58
    • 0037435881 scopus 로고    scopus 로고
    • Local inflammation increases vanilloid receptor 1 expression within distinct subgroups of DRG neurons
    • Amaya F., Oh-hashi K., Naruse Y., Iijima N., Ueda M., Shimosato G., et al. Local inflammation increases vanilloid receptor 1 expression within distinct subgroups of DRG neurons. Brain Res 963 (2003) 190-196
    • (2003) Brain Res , vol.963 , pp. 190-196
    • Amaya, F.1    Oh-hashi, K.2    Naruse, Y.3    Iijima, N.4    Ueda, M.5    Shimosato, G.6
  • 59
    • 1642360758 scopus 로고    scopus 로고
    • Distribution and immunocytochemical characterization of dorsal root ganglion neurons innervating the lumbar intervertebral disc in rats: a review
    • Aoki Y., Takahashi Y., Ohtori S., Moriya H., and Takahashi K. Distribution and immunocytochemical characterization of dorsal root ganglion neurons innervating the lumbar intervertebral disc in rats: a review. Life Sci 74 (2004) 2627-2642
    • (2004) Life Sci , vol.74 , pp. 2627-2642
    • Aoki, Y.1    Takahashi, Y.2    Ohtori, S.3    Moriya, H.4    Takahashi, K.5
  • 60
    • 0037282830 scopus 로고    scopus 로고
    • Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors
    • Bron R., Klesse L.J., Shah K., Parada L.F., and Winter J. Activation of Ras is necessary and sufficient for upregulation of vanilloid receptor type 1 in sensory neurons by neurotrophic factors. Mol Cell Neurosci 22 (2003) 118-132
    • (2003) Mol Cell Neurosci , vol.22 , pp. 118-132
    • Bron, R.1    Klesse, L.J.2    Shah, K.3    Parada, L.F.4    Winter, J.5
  • 61
    • 1542298215 scopus 로고    scopus 로고
    • Mechanisms involved in new therapies for overactive bladder
    • Cruz F. Mechanisms involved in new therapies for overactive bladder. Urology 63 (2004) 65-73
    • (2004) Urology , vol.63 , pp. 65-73
    • Cruz, F.1
  • 63
    • 0035823409 scopus 로고    scopus 로고
    • Peripheral capsaicin receptors increase in the inflamed rat hindpaw: a possible mechanism for peripheral sensitization
    • Carlton S.M., and Coggeshall R.E. Peripheral capsaicin receptors increase in the inflamed rat hindpaw: a possible mechanism for peripheral sensitization. Neurosci Lett 310 (2001) 53-56
    • (2001) Neurosci Lett , vol.310 , pp. 53-56
    • Carlton, S.M.1    Coggeshall, R.E.2
  • 64
    • 2342448512 scopus 로고    scopus 로고
    • The proportion of TRPV1 protein-positive lumbar DRG neurones does not increase in the course of acute and chronic antigen-induced arthritis in the knee joint of the rat
    • Bar K.J., Schaible H.G., Brauer R., Halbhuber K.J., and von Banchet G.S. The proportion of TRPV1 protein-positive lumbar DRG neurones does not increase in the course of acute and chronic antigen-induced arthritis in the knee joint of the rat. Neurosci Lett 361 (2004) 172-175
    • (2004) Neurosci Lett , vol.361 , pp. 172-175
    • Bar, K.J.1    Schaible, H.G.2    Brauer, R.3    Halbhuber, K.J.4    von Banchet, G.S.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.