The effects of the TRPV1 receptor antagonist SB-705498 on trigeminovascular sensitisation and neurotransmission

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 380, Issue 4, 2009, Pages 311-325

  Lambert, G A ^a,c   Davis, J B ^b   Appleby, J M ^b   Chizh, B A ^b   Hoskin, K L ^a   Zagami, A S ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

^b GLAXOSMITHKLINE   (United Kingdom)

^c UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

Dura mater; Sensitisation; TRPV1 receptor

Indexed keywords

1 (2 BROMOPHENYL) 3 [1 (5 TRIFLUOROMETHYL 2 PYRIDINYL) 3 PYRROLIDINYL]UREA; ANALGESIC AGENT; AUTACOID; DRUG DERIVATIVE; PYRROLIDINE DERIVATIVE; SB-705498; UREA; VANILLOID RECEPTOR;

ANIMAL; ARTICLE; BLOOD; BLOOD PRESSURE; BRAIN CIRCULATION; CAT; DISEASE MODEL; DRUG ANTAGONISM; DRUG EFFECT; DURA MATER; ELECTROSTIMULATION; EVOKED RESPONSE; FACE; INFLAMMATION; INNERVATION; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MIGRAINE; MYELINATED NERVE; PAIN; PAIN ASSESSMENT; PAIN THRESHOLD; PATHOPHYSIOLOGY; REACTION TIME; SKIN; SYNAPTIC TRANSMISSION; TIME; TRIGEMINAL NERVE; TRIGEMINAL NUCLEUS; VASCULARIZATION;

ANALGESICS; ANIMALS; BLOOD PRESSURE; CATS; CEREBROVASCULAR CIRCULATION; DISEASE MODELS, ANIMAL; DURA MATER; ELECTRIC STIMULATION; EVOKED POTENTIALS; FACE; INFLAMMATION; INFLAMMATION MEDIATORS; INJECTIONS, INTRAVENOUS; MIGRAINE DISORDERS; NERVE FIBERS, MYELINATED; PAIN; PAIN MEASUREMENT; PAIN THRESHOLD; PYRROLIDINES; REACTION TIME; SKIN; SYNAPTIC TRANSMISSION; TIME FACTORS; TRIGEMINAL CAUDAL NUCLEUS; TRIGEMINAL NERVE; TRPV CATION CHANNELS; UREA;

EID: 73249147876     PISSN: 00281298     EISSN: 14321912     Source Type: Journal    
DOI: 10.1007/s00210-009-0437-5     Document Type: Article

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