Upregulation of the cardiac bradykinin B2 receptors after myocardial infarction

Immunopharmacology

Volumn 44, Issue 1-2, 1999, Pages 111-117

  Tschöpe, Carsten ^a   Koch, Matthias ^a   Spillmann, Frank ^a   Heringer Walther, Silvia ^a,b   Mochmann, Hans Ch ^a   Stauss, Harald ^c   Bader, Michael ^b   Unger, Thomas ^d   Schultheiss, Heinz P ^a   Walther, Thomas ^b  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c HUMBOLDT UNIVERSITY   (Germany)

^d UNIVERSITY OF KIEL   (Germany)

Author keywords

B2 receptor; Bradykinin; Heart infarction; Kallikrein kinin system

Indexed keywords

BRADYKININ; BRADYKININ B2 RECEPTOR; COMPLEMENTARY DNA; KALLIKREIN; KININ; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HEART; HEART INFARCTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; BLOOD PRESSURE; HEART RATE; MALE; MYOCARDIAL INFARCTION; MYOCARDIUM; RATS; RATS, INBRED WKY; RECEPTOR, BRADYKININ B2; RECEPTORS, BRADYKININ; UP-REGULATION; VENTRICULAR FUNCTION, LEFT;

EID: 0345633550     PISSN: 01623109     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0162-3109(99)00116-2     Document Type: Article

References (19)

1. Baumgarten C.R., Linz W., Kunkel G., Schölkens B.A., Wiemer G. Ramiprilat increases bradykinin outflow from isolated rat hearts. Br. J. Pharmacol. 108:1993;293-295.
2. Bhoola K.D., Figueroa C.D., Worthy K. Bioregulation of kinins: kallikreins, kininogens, and kininases. Pharmacol. Rev. 44:1992;1-80.
3. Chahine R., Adam A., Yamaguchi N., Gaspo R., Regoli D., Nadeau R. Protective effects of bradykinin on the ischaemic heart: implication of the B1 receptor. Br. J. Pharmacol. 108:1993;318-322.
4. Hashimoto K., Hirose M., Furukawa K., Hayakawa H., Kimura E. Changes in hemodynamics and bradykinin concentration in coronary sinus blood in experimental coronary artery occlusion. Jpn. Heart J. 18:1977;679-680.
5. Hashimoto K., Hamamoto H., Honda Y., Hirose M., Furukawa S., Kimura E. Changes in components of kinin system and hemodynamics in acute myocardial infarction. Am. Heart J. 95:1978;619-626.
6. Kimura E., Hashimoto K., Furakawa H. Changes in bradykinin level in coronary sinus blood after the experimental occlusion of a coronary artery. Am. Heart J. 85:1973;635-647.
7. 9-bradykinin release following reperfusion of the ischemic rat heart. Br. J. Pharmacol. 115:1995;476-478.
8. Linz W., Wiemer G., Gohlke P., Unger Th., Schölkens B.A. Contribution of kinins to the cardiovascular actions of angiotensin-converting enzyme inhibitors. Pharmacol. Rev. 47(1):1995;25-49.
9. Lochner W., Parratt J.R. A comparison of the effects of locally and systematically administrated kinins on coronary blood flow and myocardial metabolism. Br. J. Pharmacol. 26:1966;17-26.
10. Marshall R.J., Parratt J.R. The early consequences of myocardial ischemia and their modification. J. Physiol. (Paris). 76:1980;699-715.
11. Martorana P.A., Kettenbach B., Breipohl G., Linz W., Schölkens B.A. Reduction of infarct size by local angiotensin-converting enzyme inhibition is abolished by a bradykinin antagonist. Eur. J. Pharmacol. 182:1990;395-396.
12. Nolly H., Carbini L.A., Scicli G., Carretero O.A., Scicli A.G. A local kallikrein-kinin system is present in hearts. Hypertension. 23:1994;919-923.
13. Parratt J.R. Endogenous myocardial protective (antiarrhythmic) substances. Cardiovasc. Res. 27:1993;693-702.
14. Pitt B., Mason J., Conti C.R., Colman R.W. Activation of the plasma kallikrein system during myocardial ischemia. Adv. Exp. Med. Biol. 8:1970;343-347.
15. Praddaude F., Tack I., Emond C., Bascands J.L., Girolami J.P., Tran-Van T., Regoli D., Ader J.L. In vivo and in vitro homologous desensitization of rat glomerular bradykinin B2 receptors. Eur. J. Pharmacol. 294:1995;173-182.
16. Rösen P., Rösen R., Hohl C., Reinauer H., Klaus W. Reduced transcoronary exchange and prostaglandin synthesis in diabetic rat heart. Am. J. Physiol. 247:1984;H563-H569.
17. Stauss H.M., Zhu Y.C., Redlich Th., Adamiak D., Mott A., Kregel K., Unger Th. ACE inhibitors in infarct induced heart failure: bradykinin versus angiotensin II. J. Cardiovasc. Risk. 1:1994;255-262.
18. Tschöpe C., Gohlke P., Zhu Y.-Z., Linz W., Schölkens B.A., Unger Th. Antihypertensive and cardioprotective effects after angiotensin-converting enzyme inhibition: role of kinins. J. Card. Failure. 3:1997;134-148.
19. Vegh A., Szekeres L., Parratt J.R. Local intracoronary infusion of bradykinin profoundly reduce the severity of ischaemia-induced arrhythmias in anaesthetised dogs. Br. J. Pharmacol. 104:1991;294-295.