Use of natural antimicrobials from a food safety perspective for control of staphylococcus aureus

Current Pharmaceutical Biotechnology

Volumn 12, Issue 8, 2011, Pages 1240-1254

  Li, Min ^a   Muthaiyan, Arunachalam ^b   O'Bryan, Corliss A ^b   Gustafson, John E ^c   Li, Y ^b,d   Crandall, Philip G ^b   Ricke, Steven C ^b  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b UNIVERSITY OF ARKANSAS   (United States)

^c NEW MEXICO STATE UNIVERSITY   (United States)

^d 3202 Bell Engineering Center   (United States)

Author keywords

Antibiotic resistance; Mrsa; Natural antimicrobials; S.aureus

Indexed keywords

ALLICIN; ANTHOCYANIN; ANTIBIOTIC AGENT; APIGENIN; BENZOIC ACID; BERGAMOT OIL; BORNEOL; CARBOXYLIC ACID; CARVACROL; CINEOLE; CINNAMALDEHYDE; ESSENTIAL OIL; EUGENOL; FLAVONE; FLAVONOID; GARLIC EXTRACT; LACTOFERRIN; LINALOOL; LUTEOLIN; NISIN; PENICILLIN G; PHENOL DERIVATIVE; PSEUDOMONIC ACID; SORBIC ACID; TEA TREE OIL; TERPENE; TERPENOID; THYMOL; UNINDEXED DRUG; VANCOMYCIN;

AGRICULTURE; ANIMAL; ANTIBIOTIC RESISTANCE; ANTIINFLAMMATORY ACTIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL INFECTION; CATERING SERVICE; CHEMICAL STRUCTURE; DRUG EFFECT; DRUG STRUCTURE; FOOD CONTAMINATION; FOOD INDUSTRY; FOOD POISONING; FOOD SAFETY; GARLIC; MASTITIS; MEDICINAL PLANT; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; NONHUMAN; PLANT; PREVALENCE; SKIN INFECTION; STAPHYLOCOCCUS AUREUS;

ANTI-INFECTIVE AGENTS; DRUG RESISTANCE, BACTERIAL; FLAVONOIDS; FOOD MICROBIOLOGY; FOOD SAFETY; IRON CHELATING AGENTS; METHICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS; OILS, VOLATILE; STAPHYLOCOCCUS AUREUS; VANCOMYCIN RESISTANCE;

ANIMALIA; BACTERIA (MICROORGANISMS); METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS AUREUS;

EID: 79960020612     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920111796117283     Document Type: Article

References (190)

1. Lowy, F. D. Antimicrobial resistance: the example of Staphylococcusaureus. J. Clin. Invest., 2003, 111, 1265-1273.
2. Holmes, A.; Ganner, M.; McGuane, S.; Pitt, T. L.; Cookson, B. D.; Kearns, A. M. Staphylococcus aureus isolates carrying Panton-Valentine leucocidin genes in England and Wales: frequency, characterizationand association with clinical disease. J. Clin. Microbiol.,2005, 43, 2384-2390.
3. Bennett, R. W. Staphylococcus aureus. In: Guide to foodbornepathogens; Labbe R. G.; Garcia S, Eds.; John Wiley & Sons, Inc.: NY, 2001, pp. 201-220.
4. Gustafson, J. E.; Wilkinson, B. J. Staphylococcus aureus as a foodpathogen: the staphylococcal enterotoxins and stress response systems. In: Griffiths, M. Ed., Understanding pathogen behaviour; Virulence stress response and resistance, Woodhead PublishingLimited: Cambridge UK, 2005, pp. 331-357.
5. Mead, P. S.; Slutsker L.; Dietz, V.; McCaig L. F.; Bresee J. S.; Shapiro C.; Griffin P. M.; Tauxe R. V. Food-related illness anddeath in the United States. Emerg. Infect. Dis., 1999, 5, 607-25.
6. Jones, T. F.; Kellum M. E.; Porter S. S.; Bell M.; Schaffner W. Anoutbreak of community-acquired foodborne illness caused by methicillin-resistant Staphylococcus aureus. Emerg. Infect Dis., 2002,8, 82-84.
7. Fridkin, S. K.; Hageman J.; McDougal L. K.; Mohammed J.; Jarvis W. B.; Perl, T. M.; Tenover F. C. Epidemiological and microbiologicalcharacterization of infections caused by Staphylococcusaureus with reduced susceptibility to vancomycin, United States,1997-2001. Clin. Infect. Dis., 2003, 36, 429-39.
8. Camargo, I. L. B. C.; Gilmore M. S. Staphylococcus aureus-Probingfor host weakness? J. Bacteriol., 2008, 190, 2253-2256.
9. Schito, G. C. The importance of the development of antibiotic resistancein Staphylococcus aureus. Clin. Microbiol. Infect.,2006,12(Suppl 1), 3-8.
10. Diekema, D. J.; Pfaller M. A.; Schmitz F. J.; Smayevsky J.; Bell, J.; Jones R. N.; Beach M.; The SENTRY Participants Group. Survey ofinfections due to Staphylococcus species: frequency of occurrenceand antimicrobial susceptibility of isolates collected in the UnitedStates, Canada, Latin America, Europe, and the Western PacificRegion for the SENTRY Antimicrobial Surveillance Program, 1997-1999. Clin. Infect. Dis., 2001, 32 (Suppl 2), S114-32.
11. Lowy, F. D. Staphylococcus aureus infections. N. Engl. J Med.,1998, 339, 520-532.
12. Jarraud, S.; Mougel C.; Thioulouse J.; Lina G.; Meugnier H.; Forey F.; Nesme X.; Etienne J.; Vandenesch F. Relationships betweenStaphylococcus aureus genetic background, virulence factors, agrgroups (Alleles), and human disease. Infect. Immun., 2002, 70, 631-641.
13. Cosgrove, S. E.; Sakoulas, G.; Perencevich, E. N.; Schwaber, M. J.; Karchmer, A. W.; Carmeli Y. Comparison of mortality associatedwith methicillin-resistant and methicillin-susceptible Staphylococcusaureus bacteremia: A meta-analysis. Clin. Infect. Dis., 2003,36,53-59.
14. Dinges, M. M.; Orwin, P. M.; Schlievert, P. M. Exotoxins ofStaphylococcus aureus. Clin. Micrbiol. Rev., 2000, 13, 16-34.
15. Dibner, J. J.; Richards, J. D. Antibiotic growth promoters in agriculture:history and mode of action. Poult. Sci. 2005, 84, 634-643.
16. Davies, J.; Davies, D. Origins and evolution of antibiotic resistance. Microbiol. Mol. Biol. Rev., 2010, 74,417-433.
17. Kluytmans, J.; van Leeuwen, W.; Goessens, W.; Holls, R.; Meser, S.; Herwaldt, L.; Bruining, H.; Heck, M.; Rost, J.; van Leeuwen, N.; van Belkum, A.; Verbruch, H. Food-initiated outbreak of methicillin-resistant Staphylococcus aureus analyzed by pheno- andgenotyping. J. Clin. Microbiol., 1995, 33, 1121-1128.
18. Hughes, J.; Mellows, G. On the mode of action of pseudomonicacid: inhibition of protein synthesis in Staphylococcus aureus. J. Antibiot., 1978, 31, 330-335.
19. Reynolds, P. E. Stucture, biochemistry and mechanism of action ofglycopeptide antibiotics. Eur. J. Clin. Microbiol. Infect. Dis., 1989,8, 943-950.
20. Falla, T. J.; Karunaratne D. N.; Hancock, E. W. R. Mode of actionof the antimicrobial peptide indolicidin. J. Bio. Chem., 1996,271,19298-19303.
21. Hooper, D. C. Mechanisms of action of antimicrobials: focus onfluoroquinolones. Clin. Infect. Dis. 2001, 32 (Suppl 1), S9-15.
22. Tenover, F. C. Mechanisms of antimicrobial resistance in bacteria. Am. J. Med., 2006,119 (6A), S3-S10.
23. Russell, A. D. Mechanisms of action, resistance, and stress adaption. In: Antimicrobials in foods. Davidson, P. M.; Sofos J. N.; Branen A. L., Eds. CRC Press: Boca Raton, FL, 2005, pp. 633-657.
24. Yeaman, M. R.; Yount N. Y. Mechanisms of antimicrobial peptideaction and resistance. Pharmacol. Rev., 2003, 55, 27-55.
25. IFT Expert Report. Antimicrobial resistance: implications for thefood system. Comp. Rev. Food Sci. Food Safety, 2006, 5, 71-137.
26. Aeschlimann, J. R. The role of multidrug efflux pumps in the antibioticresistance of Pseudomonas aeruginosa and other Gramnegativebacteria. Pharmacotherapy, 2003, 23, 916-924.
27. Hsieh, P. -C.; Siegel S. A.; Rogers B.; Davis D.; Lewis K. Bacteriallacking a multidrug pump: a sensitive tool for drug discovery. Proc. Natl. Acad. Sci. USA, 1998, 95, 6602-6606.
28. Normark, B. H.; Normark S. Evolution and spread of antibioticresistance. J. Int. Med., 2002, 252, 91-106.
29. Blázquez, J. Hypermutation as a factor contributing to the acquisitionof antimicrobial resistance. Clin. Infect. Dis., 2003, 37, 1201-1209.
30. Jensen, S. O.; Lyon, B. R. Genetics of antimicrobial resistance in Staphylococcus aureus. Future Microbiol., 2009, 4, 565-582.
31. Kümmerer, K. Resistance in the environment. J. Antimicrob. Chemother.,2004,54, 311-320.
32. Shlaes, D. M.; Gerding, D. N.; John, Jr., J. F.; Craig, W. A.; Bornstein, D. L.; Duncan, R. A.; Eckman, M. R.; Farrer, W. E.; Greene, W. H.; Lorian, V.; Levy, S.; McGowan, Jr., J. E.; Paul, S. M.; Ruskin, J.; Tenover, F. C.; Watanakunakorn, C. Society forHealthcare Epidemiology of America and Infectious Diseases SocietyofAmerica Joint Committee on the prevention of antimicrobialresistance:Guidelines for the prevention of antimicrobial resistancein hospitals. Infect. Control Hosp. Epidemiol., 1997, 25, 584-599.
33. Nield, B. S.; Holmes, A. J.; Gillings, M. R.; Recchia, G. D.; Mabbutt, B. C.; Nevalainen, K. M.; Stokes, H. W. Recovery of new integronclasses from environmental DNA. FEMS Microbiol. Lett.,2001,195, 59-65.
34. Riesenfeld, C. S.; Goodman, R. M.; Handelsman, J. Uncultured soilbacteria are a reservoir of new antibiotic resistance genes. Environ. Microbiol., 2004, 6, 981-989.
35. Nikaido H. Multidrug resistance in bacteria. Ann. Rev. Biochem.,2009, 78, 119-146.
36. Mazel, D.; Davies, J. Antibiotic resistance in microbes. Cell. Mol. Life Sci.,1999, 56, 742-754.
37. Zhou, Y. J.; Antignac, A.; Wu, S. W.; Tomasz, A. Penicillinbindingproteins and cell wall composition in beta-lactam-sensitiveand -resistant strains of Staphylococcus sciuri. J. Bacteriol.,2008,190, 508-514.
38. Jensen, S. O.; Lyon, B. R. Genetics of antimicrobial resistance in Staphylococcus aureus. Future Microbiol., 2009, 4, 565-582.
39. Barrett, J. MRSA - what is it, and how do we deal with the problem?Expert Opin. Ther. Targets. 2005, 9, 253-264.
40. Nicolle, L. E.; Dyck, B.; Thompson, G.; Roman, S.; Kabani, A.; Plourde, P.; Fast, M.; Embil, J. Regional dissemination and controlof epidemic methicillin-resistant. Staphylococcus aureus. Infect. Control. Hosp. Epidemiol., 1999, 20, 202-205.
41. Cunha, B. A. Methicillin-resistant Staphylococcus aureus: clinicalmanifestations and antimicrobial therapy. Clin. Microbiol. Infect.,2005, 11, 33-42.
42. Simor, A. E.; Stuart, T. L.; Louie, L.; Watt, C.; Ofner-Agostini, M.; Gravel, D. M.; Mulvey, M.; Loeb, M.; McGeer, A.; Bryce, E.; Matlow,A. Mupirocin-resistanct, methicillin-resistant Staphylococcusaureus strains in Canadian hospitals. Antimicrob. AgentsCemother., 2007, 1, 3880-3886.
43. Elston, D. M. Community-acquired methicillin-resistant Staphylococcusaureus. J. Am. Acad. Dermatol. 2007, 56, 1-16.
44. David, M. Z.; Daum, R. S. Community-associated methicillinresistantStaphylococcus aureus: epidemiology and clinical consequencesof an emerging epidemic. Clin. Microbiol. Rev., 2010,23,616-687.
45. Appelbaum, P. C. MRSA--the tip of the iceberg. Clin. Microbiol. Infect., 2006,12 (Supp 2), 3-10.
46. Pfeltz, R. F.; Wilkinson, B. J. The escalating challenge of vancomycinresistance in Staphylococcus aureus. Curr. Drug Targets Infect. Disord., 2004, 4, 273-294.
47. Hiramatsu, K. Vancomycin-resistant Staphylococcus aureus: a newmodel of antibiotic resistance. Lancet Infect Dis., 2001, 1, 147-55.
48. Koehl, J. L.; Muthaiyan, A.; Jayaswal, R. K.; Ehlert, K.; Labischinski, H.; Wilkinson, B. J. Cell wall composition and decreasedautolysis and lysostaphin-susceptibility of glycopeptideintermediate Staphylococcus aureus. Antimicrob. Agents Chemother.,2004, 48, 3749-3757.
49. Levy S. B.; Marshall, B. Antibacterial resistance worldwide:causes, challenges and responses. Nat. Med. Suppl., 2004, 10,S122-S129.
50. Lee, J. H. Methicillin (Oxacillin)-resistant strains isolated frommajor food animals and their potential transmission to human. Appl. Environ. Microbiol., 2003, 11, 6489-6494.
51. Donskey, C. J. The role of the intestinal tract as a source for transmissionof nosocomial pathogens. Curr. Infect. Dis. Rep., 2004, 6,420-425.
52. Conly, J. Antimicrobial resistance in Canada. Can. Med. Assoc. J., 2002, 167, 885-891.
53. Wenzel, R. P.; Edmond, M. B. Managing antimicrobial resistance. N. Engl. J. Med., 2000, 343, 1961-1963.
54. Normanno, G.,; Corrente, M.; La Salandra, G.; Dambrosio, A.; Quaglia, N. C.; Parisi, A.; Greco, G.; Bellacicco, A. L.; Virgilio, S.; Celano, G. V. Methicillin-resistant Staphylococcus aureus(MRSA) in foods of animal origin product in Italy. Int. J. Food Microbiol., 2007,117, 219-222.
55. Marshall, S. H.; Arenas, G. Antimicrobial peptides: A natural alternativeto chemical antibiotics and a potential for applied biotechnology. Electron. J. Biotechnol., 2003, 6(3). http://www.scielo.cl/scielo.php?pid=S0717-34582003000300011&script=sci-arttext(Accessed 8 June 2010).
56. Sofos, J. N.; Beuchat, L. R.; Davidson, P. M.; Johnson, E. A. Naturallyoccurring antimicrobials in food. Reg. Tox. Pharm., 1998, 28,71-72.
57. López-Malo, A.; Alzamora, S. M.; Guerrero, S. Natural antimicrobialsfrom plants. In: Minimally processed fruits and vegetables:fundamental aspects and applications. Alzamora, S. M.; Tapia, M. S.; López-Malo A., Eds. Aspen Publication: Gaithersburg, MD,2000, pp. 237-258.
58. Rahman, M. M.; Gray, A. I. Antimicrobial constituents from thestem bark of Feronia limonia. Phytochem., 2002, 59, 73-77.
59. Zhu, X.; Zhang, H.; Lo, R. Phenolic compounds from the leafextract of artichoke (Cynara scolymus L.) and their antimicrobialactivities. J. Agric. Food Chem., 2004, 52, 7272-7278.
60. Erasto, P.; Bojase-Moleta, G.; Majinda, R. R. T. Antimicrobial andantioxidant flavonoids from the root wood of Bolusanthus speciosus. Phytochem., 2004, 65, 875-880.
61. di Pasqua, R.; de Feo, V.; Villani, F.; Mauriello, G. In vitro antimicrobialactivity of essential oils from Mediterranean Apiaceae,Verbenaceae and Lamiaceae against foodborne pathogens andspoilage bacteria. Ann. Microbiol., 2005, 55, 139-143.
62. Ricke, S. C.; Kundinger, M. M.; Miller, D. R.; Keeton, J. T. Alternativesto antibiotics: chemical and physical antimicrobial interventionsand foodborne pathogen response. Poult. Sci., 2005, 84, 667-675.
63. Yu, J.; Lei, J.; Yu, H.; Cai, X.; Zou, G. Chemical composition andantimicrobial activity of the essential oil of Scutellaria barbata. Phytochem., 2004, 65, 881-884.
64. Smith-Palmer, A.; Stewart, J.; Fyfe, L. The potential application ofplant essential oils as natural food preservatives in soft cheese. Food Microbiol., 2001, 18, 463-470.
65. Matan, N.; Rimkeeree, H.; Mawson, A. J.; Chompreeda, P.; Haruthaithanasan,V.; Parker, M. Antimicrobial activity of cinnamonand clove oils under modified atmosphere conditions. Int. J. FoodMicrobiol., 2006,107, 180-185.
66. Lambert, R. J. W.; Skandamis, P. N.; Coote, P. J.; Nychas, G. J. E. A study of the minimum inhibitory concentration and mode of actionof oregano essential oil, thymol and carvacrol. J. Appl. Microbiol., 2001, 91, 453-462.
67. Mau, J. L.; Chen, C. P.; Hsien, P. C. Antimicrobial effect of extractsfrom Chinese chive, cinnamon, and corni fructus. J. Agric. Food Chem., 2001, 49, 183-188.
68. Burt, S. Review: Essential oils: their antibacterial properties andpotential applications in foods-a review. Int. J. Food Microbiol.,2004, 94, 223-253.
69. Nychas, G. J. E.; Skandamis, P. N. Antimicrobials from herbs andspices. In: Natural antimicrobials for the minimal processing offoods, Roller, S, Ed. CRC Press: Boca Raton, FL, 2003, pp. 176-200.
70. Yanishlieva, N.; Marinova, V. E.; Pokorny, J. Natural antioxidantsfrom herbs and spices. Eur. J. Lipid Sci. Technol., 2006, 108, 6-793.
71. Maidment, C.; Dyson, A.; Haysom, I. A study into the antimicrobialeffects of cloves (Syzgium aromaticum) and cinnamon (Cinnamomumzeylanicum) using disc-diffusion assay. Nut. Food Sci.,2006, 36, 225-230.
72. Chorianopoulos, N. G.; Lambert, R. J. W.; Skandamis, P. N.; Evergetis, E. T.; Haroutounian, S. A.; Nychas, G. -J. E. A newly developedassay to study the minimum inhibitory concentration ofSatureja spinosa essential oil. J. Appl. Microbiol., 2006,100, 778-786.
73. Walsh, S. E.; Maillard, J. -Y.; Russell, A. D.; Catrenich, C. E.; Charbonneau, D. L.; Bartolo, R. G. Activity and mechanisms of actionof selected biocidal agents on Gram-positive and -negativebacteria. J. Appl. Microbiol., 2003, 94, 240-247.
74. Nosto, A.; Blanco, A. R.; Cannatelli, M. A.; Enea, V.; Flamini, G.; Morelli, I.; Roccaro, A. S.; Alonzo, V. Susceptibility of methicillinresistantstaphylococci to oregano essential oil, carvacrol and thymol. FEMS Microbiol. Lett., 2004, 230, 191-195.
75. Nosto, A.; Roccaro, A. S.; Bisignano, G.; Marino, A.; Cannatelli, M. A.; Pizzimenti, F. C.; Cioni, P. L.; Procopio, F.; Blanco, A. R. Effects of oregano, Carvacrol and thymol on Staphylococcusaureus and Staphylococcus epidermidis biofilms. J. Med. Microbiol.,2007, 56, 519-523.
76. Palaniappan, K.; Holley, R. A. Use of natural antimicrobials toincrease antibiotic susceptibility of drug resistant bacteria. Int. J. Food Microbiol., 2010, 140, 164-168.
77. Butt, M. S.; Sultan, M. T.; Butt, M. S.; Iqbal, J. Garlic: nature'sprotection against physiological threats. Crit. Rev. Food Sci. Nutr.,2009, 49, 538-551.
78. Rivlin, R. S. Historical perspective on the use of garlic. J. Nutr.,2001, 131(3s), 951S-954S.
79. Cavalitto, J. C.; Bailey, J. H. Allicin, the antibacterial principle ofAllium sativum. I. Isolation, physical properties and antibacterialaction. J. Am. Chem. Soc., 1944, 66, 1950-1951.
80. Ankri, S.; Mirelman, D. Antimicrobial properties of allicin fromgarlic. Microb. Infect., 1999, 1, 125-129.
81. Cutler, R. R.; Wilson, P. Antibacterial activity of a new, stable,aqueous extract of allicin against methicillin-resistant Staphylococcusaureus. Br. J. Biomd. Sci., 2004, 61, 71-74.
82. Beuchat, L. R. Control of foodborne pathogens and spoilage microorganismsby naturally occurring antimicrobials. In: Microbialfood contamination, 2nd ed. Wilson, C. L., Ed. CRC Press: BocaRaton, FL, 2008, pp. 319-345.
83. Feldberg, R. S.; Chang, S. C.; Kotic, A. N. In vitro mechanism ofinhibition of bacterial cell growth by allicin. Antimicrob. AgentsChemother., 1988, 32, 1763-1768.
84. Fujisawa, H.; Watanabe, K.; Suma, K.; Origuchi, K.; Matsufuji, H.; Seki, T.; Ariga, T. Antibacterial potential of garlic-derived allicinand its cancellation by sulfhydryl compounds. Biosci. Biotechnol. Biochem., 2009, 73, 1948-1955.
85. Mandalari, G.; Bennett, R. N.; Bisignano, G.; Trombetta, D.; Saija, A.; Faulds, C. B.; Gasson, M. J.; Narbad, A. Antimicrobial activityof flavonoids extracted from bergamot (Citrus bergamia Risso)peel, a byproduct of the essential oil industry. J. Appl. Microbiol.,2007, 103, 2056-2064.
86. Cushnie, T. P. T.; Lamb, A. J. Antimicrobial activity of flavonoids. Int. J. Antimicrob. Agents., 2005, 26, 343-356.
87. Fisher, K.; Phillips, C. A. The effect of lemon, orange and bergamotessential oils and their components on the survival of Campylobacterjejuni, Escherichia coli O157, Listeria monocytogenes,Bacillus cereus and Staphylococcus aureus in vitro and in food systems. J. Appl. Microbiol., 2006, 101(6), 1232-1240.
88. Hirai, I.; Okuno, M.; Katsuma, R.; Arita, N.; Tachibana, M.; Yamamoto,Y. Characterisation of anti-Staphylococcus aureus activityof quercetin. Int. J. Food Sci. Technol., 2010, 45, 1250-1254.
89. Mattana, C. M.; Satorres, S. E.; Sosa, A.; Fusco, M.; Alcaraz, L. E. Antibacterial activity of extracts of Acacia aroma against methicillin-resistant and methicillin-sensitive Staphylococcus. Brazilian J. Microbiol., 2010, 41, 581-587.
90. Hsieh, P-C.; Mau, J. -L.; Huang, S. -H. Antimicrobial effect of variouscombinations of plant extracts. Food Microbiol., 2001, 18, 35-43.
91. Sato, Y.; Suzaki, S.; Nishikawa, T.; Kihara, M.; Shibata, H.; Higuti,T. Phytochemical flavones isolated from Scutellaria barbataand antibacterial activity against methicillin-resistant Staphylococcusaureus. J. Enthnopharmacol., 2000, 72, 483-488.
92. Cox, S. D.; Mann, C. M.; Markham, J. L.; Bell, H. C.; Gustafson, J. E.; Warmington, J. R.; Wyllie, S. G. The mode of antimicrobial actionof the essential oil of Melaleuca alternifolia (tea tree oil). J. Appl. Bacteriol., 2000, 88, 170-175.
93. Vigil, A. L. Z.; Palou, E.; Alzamora, S. M. Naturally occurringcompounds-plant sources. In: Antimicrobials in foods. Davison, P. M.; Sofos, J. N.; Branen, A. L., Eds. CRC Press: Boca Raton, FL,2001, pp. 429-451.
94. Guinoiseau, E.; Luciani, A.; Rossi, P. G.; Quilichini, Y.; Ternengo, S.; Bradesi, P.; Berti, L. Cellular effects induced by Inula graveolensand Santolina corsica essential oils on Staphylococcus aureus. Eur. J. Clin. Microbiol. Infect. Dis., 2010, 29, 873-879.
95. Smith-Palmer, A.; Stewart, J.; Fyfe, L. Antimicrobial properties ofplant essential oils and essences against five important foodbornepathogens. Lett. Appl. Microbiol., 1998, 26, 118-122.
96. Fisher, K.; Phillips, C. The mechanism of action of a citrus oilblend against Enterococcus faecium and Enterococcus faecalis. J. Appl. Microbiol., 2009, 106, 1343-1349.
97. Prindle, R. F.; Wright, E. S. Phenolic compounds. In: Disinfection,sterilization and preservation, Block, S. S., Ed. Lea & Febiger:Philadelphia, 1977, pp. 219-251.
98. Holley, R. A.; Patel, D. Improvement in shelf-life and safety ofperishable foods by plant essential oils and smoke antimicrobials. Food Microbiol., 2005, 22, 273-292.
99. Sikkema, J.; De Bont, J. A. M.; Poolman, B. Interactions of cyclichydrocarbons with biological membranes. J. Biol. Chem., 1994,269, 8022-8028.
100. Ultee, A.; Bennik, M. H. J.; Moezelaar, R. The phenolic hydroxylgroup of carvacrol is essential for action against the food-bornepathogen Bacillus cereus. Appl. Environ. Microbiol., 2002, 68,1561-1568.
101. Carson, C. F.; Riley, T. V. Antimicrobial activity of the majorcomponents of the essential oil of Melaleuca alternifolia. J. Appl. Bacteriol., 1995, 78, 264-269.
102. Tassou, C. C.; Drosinos, E. H.; Nychas, G. -J. E. Effects of essentialoil from mint (Mentha piperita) on Salmonella enteritidis andListeria monocytogenes in model food system at 4oC and 10oC. J. Appl. Bacteriol., 1995, 78, 593-600.
103. Juven B. J.; Kanner, J.; Schved, F.; Weisslowicz, H. Factors thatinteract with the antibacterial action of thyme essential oil and itsactive constituents. J. Appl. Bacteriol., 1994, 76, 626-631.
104. Sivropoulou, A.; Papanikolaou, E.; Nikolaou, C.; Kokkini, S.; Lanaras, T.; Arsenakis, M. Antimicrobial and cytotoxic activities ofOriganum essential oils. J. Agric. Food Chem., 1996,44, 1202-1205.
105. Sivropoulou, A.; Kokkini, S.; Lanaras, T.; Arsenakis, M. Antimicrobialactivity of mint essential oils. J. Agric. Food Chem., 1995,43, 2384-2388.
106. Scannell, A. G. M.; Hill, C.; Buckley, D. J.; Arendt, E. K. Determinationof the influence of organic acids and nisin on shelf-life andmicrobiological safety aspects of fresh pork sausage. J. Appl. Microbiol.,1997, 83, 407-412.
107. Eifert, J. D.; Hackney, C. R.; Pierson, M. D.; Duncan, S. E.; Eigel, W. N. Acetic, lactic and hydrochloric acid effects on Staphylococcusaureus 196E growth based on a predictive model. J. Food Sci.,1997, 62, 174-178.
108. Lund, B. M.; Eklund, T. Control of pH and use of organic acids. In:The Microbiological Safety and Quality of Food, Lund, B. M.,Baird-Parker, T. C.; Gould, G. W., Eds. Aspen Publishers: Maryland,2000, pp. 738-758.
109. Russell, A. D. Another explanation for the toxicity of fermentationacids at low pH - anion accumulation versus uncoupling. J. Appl. Bacteriol.,1992, 73, 363-370.
110. Samelis, J.; Sofos, J. N. Organic acids. In: Natural antimicrobialsfor the minimal processing of foods, Roller, S., Ed. CRC Press:Boca Raton, FL, 2003, pp. 98-132.
111. Coroller, L.; Guerrot, V.; Huchet, V.; Marc, Y. L.; Mafart, P.; Sohier, D.; Thuault, D. Modelling the influence of single acid andmixture on bacterial growth. Int. J. Food Microbiol., 2005, 100,167-178.
112. Greer, G. G.; Dilts, B. D. Factors affecting the susceptibility ofmeatborne pathogens and spoilage bacteria to organic acids. FoodRes. Int., 1992, 25, 355-364.
113. Dubal, Z. B.; Paturkar, A. M.; Waskar, V. S.; Zende, R. J.; Latha, C.; Rawool, D. B.; Kadam, M. M. Effect of food grade organic acidson inoculated S. aureus, L. monocytogenes, E. coli and S. Typhimuriumin sheep/goat meat stored at refrigeration temperature. Meat Sci., 2004, 66, 817-821.
114. Kussendrager, K. D.; van Hooijdionk, A. C. M. Lactoperoxidase:physico-chemical properties, occurrence, mechanism of action andapplications. Brit. J. Nutr., 2000, 84 (suppl. 1), S19-S25.
115. Moshynskyy, I.; Jiang, M.; Fontaine, M. C.; Perez-Casal, J.; Babiuk, L. A.; Potter, A. A. Characterization of a bovine lactoferrinbinding protein of Streptococcus uberis. Microb. Pathog. 2003, 35,203-215.
116. Naidu, A. S. Antimicrobials from animals. In: Natural antimicrobialsfor the minimal processing of foods. Roller, S., Ed. CRC Press:Boca Raton, FL, 2003, pp. 133-157.
117. Korhonen, H.; Marnila, P.; Gill, H. S. Milk immunoglobulins andcomplement factors. Br. J. Nutr., 2000, 84(Suppl. 1), S75-S80.
118. Naidu, A. S.; Andersson, M.; Forsgren, A. Identification of a humanlactoferrin-binding protein in Staphylococcus aureus. J. Med. Microbiol., 1992, 36, 177-183.
119. Baker, E. N.; Baker, H. M. Molecular structure, binding propertiesand dynamics of lactoferrin. Cell. Mol. Life Sci., 2005, 62, 2531-2539.
120. Lacasse, P.; Lauzon, K.; Diarra, M. S.; Petitclerc, D. Utilization oflactoferrin to fight antibiotic-resistant mammary gland pathogens. J. Anim. Sci.,2008, 86, 66-71.
121. Bellamy, W.; Takase, M.; Yamauchi, K.; Wakabayashi, H.; Kawase, K.; Tomita, M. Identification of the bactericidal domain oflactoferrin. Biochim. Biophys. Acta., 1992, 1121, 130-136.
122. Murdock, C. A.; Matthews, K. R. Antibacterial activity of pepsindigestedlactoferrin on foodborne pathogens in buffered broth systemsand ultra-high temperature milk with EDTA. J. Appl. Microbiol.,2002, 93, 850-856.
123. Aguila A.; Herrera, A. G.; Morrison, D.; Cosgrove, B.; Perojo, A.; Montesinos, I.; Pérez, J.; Sierra, G.; Gemmell, C. G.; Brock, J. H. Bacteriostatic activity of human lactoferrin against Staphylococcusaureus is a function of its iron-binding properties and is not influencedby antibiotic resistance. FEMS Immunol. Med. Microbiol.,2001, 31, 145-152.
124. Diarra, M. S.; Petitclerc, D.; Lacasse, P. Effect of lactoferrin incombination with penicillin on the morphology and the physiologyof Staphylococcus aureus isolated from bovine mastitis. J. DairySci., 2002, 85, 1141-1149.
125. Petitclerc, D.; Lauzon, K.; Cochu, A.; Ster, C.; Diarra, M. S.; Lacasse, P. Efficacy of a lactoferrin-penicillin combination to treat β-lactam-resistant Staphylococcus aureus mastitis. J. Dairy Sci.,2007, 90, 2778-2787.
126. Naidu, A. S.; Anderson, M.; Miedzobrodzki, J.; Forsgren, A.; Watts, J. L. Bovine lactoferrin receptors in Staphylococcus aureusisolated from bovine mastitis. J. Diary Sci., 1991, 74, 1218-1226.
127. Ibrahim, H. R.; Iwamori, E.; Sugimoto, Y.; Aoki, T. Identificationof a distinct antibacterial domain within the N-lobe of ovotransferrin. Biochim. Biophys. Acta., 1998, 1401, 289-303.
128. Ibrahim, H. R.; Sugimoto, Y.; Aoki, T. Ovotransferrin antimicrobialpeptide (OTAP-92) kills bacteria through a membrane damagemechanism. Biochim. Biophys. Acta., 2000, 1523, 196-205.
129. Ko, K. Y.; Mendonca, A. F.; Ahn, D. U. Effect of ethylenediaminetetraacetateand lysozyme on the antimicrobial activity ofovotransferrin against Listeria monocytogenes. Poult Sci., 2008, 87,1649-1658.
130. Wellman-Labadie, O.; Picman, J.; Hincke, M. T. Comparativeantibacterial activity of avian egg white protein extracts. Br. PoultrySci., 2008, 49, 125-132.
131. Seol, K. H.; Lim, D. G.; Jang, A.; Jo, C.; Lee, M. Antimicrobialeffect of kappa-carrageenan-based edible film containing ovotransferrinin fresh chicken breast stored at 5 degrees C. Meat Sci., 2009,83, 479-483.
132. Bosch, E. H.; Van Doorne, H.; De Vries, S. The lactoperoxidasesystem: the influence of iodide and the chemical and antimicrobialstability over the period of about 18 months. J. Appl. Microbiol.,2000, 89, 215-224.
133. Kennedy, M.; O'Rourke, A. -L.; McLay, J.; Simmonds, R. Use of aground beef model to assess the effect of the lactoperoxidase systemon the growth of Escherichia coli O157:H7, Listeria monocytogenesand Staphylococcus aureus in red meat. Int. J. Food Microbiol.,2000, 57, 147-158.
134. Elliot, R. M.; McLay, J. C.; Kennedy, M. J.; Simmonds, R. S. Inhibitionof foodborne bacteria by the lactoperoxidase system in a beefcube system. Int. J. Food Microbiol., 2004, 91, 73-81.
135. McLay, J. C.; Kennedy, M. J.; O'Rourke, A. -L.; Elliot, R. M.; Simmonds, R. S. Inhibition of bacterial foodborne pathogens by thelactoperoxidase system in combination with monolaurin. Int. J. Food Microbiol., 2002, 73, 1-9.
136. Nelson, C. A.; Roof, R. W.; McCourt, D. W.; Unanue, E. R. Identification of the naturally processed form of hen egg whitelysozyme bound to the murine major histocompatibility complexclass II molecule I-Ak. Proc. Natl. Acad. Sci., 1992, 89, 7380-7383.
137. Ibrahim, H. R.; Higashiguchi, S.; Juneja, L. R.; Kim, M.; Yamamoto, T. A structural phase of heat-denatured lysozyme with novelantimicrobial action. J. Agric. Food Chem., 1996, 44, 1416-1423.
138. Cisani, G.; Varaldo, P. E.; Grazi, G.; Soro, R. High-level potentiationof lysostaphin anti-staphylococcal activity by lysozyme. Antimicrob. Agents. Chemother., 1982, 21, 531-535.
139. Amiri, S.; Ramezani, R.; Aminlari, M. Antibacterial activity ofdextran-conjugated lysozyme against Escherichia coli and Staphylococcusaureus in cheese curd. J. Food Prot., 2008, 71, 411-415.
140. Ogra, S. S.; Ogra, P. L. Immunologic aspects of human colostrumand milk. I. Distribution characteristics and concentrations of immunoglobulinsat different times after the onset of lactation. J. Pediatr.,1978, 92, 546-549.
141. Leslie, G. A.; Clem, L. W. Phylogeny of immunoglobulin structureand function. 3. Immunoglobulins of the chicken. J. Exp. Med.,1969, 130, 1337-1352.
142. Chamow, S. M.; Ashkenazi, A. Immunoadhesins: principles andapplications. Trend. Biotech., 1996, 14, 52-60.
143. Davies, D. R.; Chacko, S. Antibody structure. Acc. Chem. Res.,1993, 26, 421-427.
144. Delves, P. J.; Roitt, I. M. The immune system-second of two parts. N Engl. J. Med., 2000, 343, 108-117.
145. Schopfer, K.; Douglas, S. D.; Wilkinson, B. J. Immunoglobulin Eantibodies against Staphylococcus aureus cell walls in the sera ofpatients with hyperimmunoglobulinemia E and recurrent staphylococcalinfection. Inf. Immun., 1980, 27, 563-568.
146. King, B. F.; Wilkinson, B. J. Binding of human immunoglobulin Gto protein A in encapsulated Staphylococcus aureus. Inf. Immun.,1981, 33, 666-672.
147. Guidry, A. J.; Berning, L. M.; Hambleton, C. N. Opsonization ofStaphylococcus aureus by bovine immunoglobulin isotypes. J. Dairy Sci., 1993, 76, 1285-1289.
148. Gorter, A.; Hiemstra, P. S.; Leijh, P. C. J.; van der Sluys, M. E.; van den Barselaar, M. T.; van Es, L. A.; Daha, M. R. IgA- and secretoryIgA-opsonized S. aureus induce a respiratory burst andphagocytosis by polymorphonuclear leucocytes. Immunol., 1987,61, 303-309.
149. Vernachio, J. H.; Bayer, A. S.; Ames, B.; Bryant, D.; Prater, B. D.; Syribeys, P. J.; Gogovits, E. L.; Patti, J. M. Human immunoglobulinG recognizing fibrinogen-binding surface proteins is protectiveagainst both Staphylococcus aureus and Staphylococcus epidermidisinfections in vivo. Antimicrob. Agents Chemotherap., 2006,50, 511-518.
150. Naidu, A. S.; Bidlack, W. R.; Clemens, R. A. Probiotic spectra oflactic acid bacteria (LAB). Crit. Rev. Food Sci. Nutr., 1999, 39, 13-126.
151. Yanagisawa, T.; Lee, J. T.; Wu, H. C.; Kawakami, M. Relationshipof protein structure of isoleucyl-tRNA synthetase with pseudomonicacid resistance of Escherichia coli. A proposed mode of actionof pseudomonic acid as an inhibitor of isoleucyl-tRNA synthetase. J. Biol. Chem. 1994, 269, 24304-24309.
152. Jones, P. G.; Sura, T.; Harris, M.; Strother A. Mupirocin resistancein clinical isolates of Staphylococcus aureus. Infect. Control Hosp. Epidemiol. 2003, 24, 300-301.
153. Cookson, B. D. The emergence of mupirocin resistance: a challengetoinfection control and antibiotic prescribing practice. J. Antimicrob. Chemother., 1998, 41, 11-18.
154. Chaves, F.; García-Martínez, J.; de Miguel, S.; Otero J. R. Molecular characterization of resistance to mupirocin in methicillin-susceptible and -resistant isolates of Staphylococcus aureusfrom nasal samples. J. Clin. Microbiol., 2004, 42, 822-824.
155. Walker, E. S.; Vasquez, J. E.; Dula, R.; Bullock, H.; Sarubbi, F. A. Mupirocin-resistant, methicillin-resistant Staphylococcus aureus:does mupirocin remain effective? Infect. Control Hosp. Epidemiol.,2003, 24, 342-346.
156. Semret, M.; Miller, M. A. Topical mupirocin for eradication ofMRSA colonization with mupirocin-resistant strains. Infect. ControlHosp. Epidemiol., 2001, 9, 578-580.
157. Davies, J.; Gilbert, W.; Gorini, L. Streptomycin, suppression, andthe code. Biochem., 1964, 51, 883-890.
158. Finken, M.; Kirschner, P.; Meier, A.; Wrede, A.; Bottger, E. C. Molecular basis of streptomycin resistance in Mycobacterium tuberculosis:alterations of the ribosomal protein S12 gene and pointmutations withina functional 16S ribosomal RNA pseudoknot. Mol. Microbiol., 1993,9, 1239-1246.
159. Nordstrom, K.; Lindberg, M. Effects of streptomycin and novobiocinon Staphylococcus aureus gene expression. J Bacteriol.,1978,133, 614-620.
160. Uwaezuoke, J. C.; Aririatu, L. E. A survey of antibiotic resistantStaphylococcus aureus strains from clinical sources in Owerri. J. Appl. Sci. Environ. Mgt., 2004, 8, 67-69.
161. Rosenwald, A. J.; Lincoln, R. E. Streptomycin inhibition of elaborationof staphylococcal enterotoxic protein. J. Bacteriol., 1966, 92,279-280.
162. Kondo, S.; Ikeda, Y.; Hattori, S.; Hamada, M.; Takeuchi, T. Susceptibilityof methicillin-resistant Staphylococcus aureus to variousantibiotics. Classification by aminoglycoside-modifying enzymesand antibiotics active against MRSA. Jpn. J. Antibiot., 1991, 44,1211-1215.
163. Severina, E.; Severin, A.; Tomasz, A. Antibacterial efficacy ofnisin against multidrug-resistant Gram-positive pathogens. J. Antimicrob. Chemother., 1998, 41, 341-347.
164. van de Ven, F. J.; Van den Hooven, H. W.; Konings, R. N.; Hilbers,C. W. NMR studies of lantibiotics: the structure of nisin inaqueous solution. Eur. J. Biochem., 1991, 202, 1181-1186.
165. Wang, X.; Liu, Y.; Xie, B.; Shi, X.; Zhou, J.; Zhang, H. Effect ofnisin on the growth of Staphylococcus aureus determined by a microcalorimetricmethod. Mol. Nutr. Food Res., 2005, 9, 350-354.
166. Abee, T.; Rombouts, F. M.; Hugenholtz, J.; Guihard, G.; Letellier, L. Mode of action of nisin Z against Listeria monocytogenes ScottA grown at high and low temperatures. Appl. Environ Microbiol.,1994, 60, 1962-1968.
167. Breukink, E. A lesson in efficient killing from two-componentlantibiotics. Molecular Microbiol., 2006, 61, 271-273.
168. Thomas, L. V.; Delves-Groughton, J. Nisin. In: Antimicrobials infoods. Davidson, P. M.,; Sofos, J. N.; Branen, A. L., Eds. CRCPress: Boca Raton, FL, 2005, pp. 237-274.
169. Brumfitt, W.; Salton, M. R. J.; Hamilton-Miller, J. M. T. Nisin, alone and combined with peptidoglycan-modulating antibiotics:activity against methicillin-resistant Staphylococcus aureus andvancomycin-resistant enterococci. J. Antimicrob. Chemother.,2002, 50, 731-734.
170. Fowler, G. G. The potential of nisin. Food Manufact., 1979, 54, 57-59.
171. Gregory, M. E.; Henry, K. M.; Kon, S. K. Nutritive properties offreshly prepared and stored evaporated milks manufactured by anormal commercial procedure or by reduced thermal processes inthe presence of nisin. J. Dairy Red., 1964, 31,113-119.
172. Heinemann, B.; Voris, L.; Stumbo, C. R. Use of nisin in processingfood products. Food Technol., 1965, 19, 592-596.
173. Ogden, K. Nisin: a bacteriocin with a potential use in brewing. J. Inst. Brewing, 1986, 92, 379-383.
174. Chung, K-T.; Dickson, J. S.; Crouse, J. D. Effects of nisin on growthof bacteria attached to meat. J. Food Protect., 1989, 55, 1329-1333.
175. Jay, J. M. Antimicrobial properties of diacetyl. Appl. Environ. Microbiol., 1982, 44, 525-532.
176. Bowles, B. L.; Juneja, V. K. Inhibition of foodborne bacterialpathogens by naturally occurring food additives. J. Food Safety,1998, 18, 101-112.
177. Lanciotti, R.; Patrignani, F.; Bagnolini, F.; Guerzoni, M. E.; Gardini, F. Evaluation of diacetyl antimicrobial activity against Escherichiacoli. Listeria monocytogenes and Staphylococcus aureus. Food Microbiol., 2003, 20, 537-543.
178. Bowles, B. L.; Sackitey, S. K.; William, A. C. Inhibitory effect offlavour compounds on Staphylococcus aureus WRRC B124. J. Food Safety, 1995, 15, 337-347.
179. Kulshrestha, D. C.; Marth, E. H. Inhibition of bacteria by somevolatile and nonvolatile compounds associated with milk. III. Stapylococcus aureus. J. Milk Food Technol., 1974, 37, 545-550.
180. Novick, R. P. Combating impervious bugs. Science, 2008, 319, 910-11.
181. Benowitz, A. B.; Hoover, J. L.; Payne, D. J. Antibacterial drugdiscovery in the age of resistance. Microbe, 2010, 5, 390-396.
182. Spellberg, B.; Powers, J. H.; Brass, E. P.; Miller, L. G.; Edwards, Jr. J. E. Trends in antimicrobial drug development: implications forthe future. Clin. Infect. Dis., 2004, 38, 1279-1286.
183. Overybye, K. M.; Barrett, J. Antibiotics: where did we go wrong? Drug Discov. Today 2005, 10, 45-52.
184. McChesney, J. D.; Venkataraman, S. K.; Henri, J. T. Plant naturalproducts: Back to the future or into extinction? Phytochemistry, 2007, 68, 2015-2022.
185. Patwardhan, B.; Mashelkar, R. A. Traditional medicine-inspiredapproaches to drug discovery: can Ayurveda show the way forward? Drug Dis. Today, 2009, 14, 804-811.
186. Hibbard, J. S.; Combined antimicrobial therapy-can we outsmart themicrobes? Microbe, 2007, 2, 271.
187. Chang, S. T.; Chen, P. I.; Chang, S. C. Antibacterial activity of leafessential oils and their constituents from Cinnamomum Osmophloeum. J. Ethnopharm., 2001, 77, 123-127.
188. Hammer, K. A.; Carson, C. F.; Riley, T. V. Antimicrobial activityof essential oils and other plant extracts. J. Appl. Microbiol., 1999,86, 985-990.
189. Campo, J. D.; Amiot, M. -J.; Nguyen-The, C. Antimicrobial effectof rosemary extracts. J. Food Prot., 2000, 63, 1359-1368.
190. Cosentino, S.; Tuberoso, C. I. G.; Pisano, B.; Satta, M.; Mascia, V.; Arzedi, E.; Palmas, F. In-vitro antimicrobial activity and chemicalcomposition of Sardinian Thymus essential oils. Lett. Appl. Microbiol.,1999, 29, 130-135.