Advances in immunology: The immune system (Second of two parts)

New England Journal of Medicine

Volumn 343, Issue 2, 2000, Pages 108-117

  Delves, Peter J ^a   Roitt, Ivan M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN SPECIFICITY; CELL PROTECTION; EFFECTOR CELL; EPITHELIUM CELL; HELPER CELL; IMMUNE RESPONSE; IMMUNOLOGY; LYMPHOCYTE; LYMPHOID TISSUE; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE ACTIVATION; ANIMAL; ANTIBODY PRODUCTION; CELLULAR IMMUNITY; HUMAN; IMMUNE SYSTEM; IMMUNITY; MOUSE; MOUSE MUTANT; PHYSIOLOGY; TRANSGENIC ANIMAL;

ANTIBODY;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; ANTIBODIES; ANTIBODY FORMATION; HUMANS; IMMUNE SYSTEM; IMMUNITY; IMMUNITY, CELLULAR; LYMPHOCYTES; LYMPHOID TISSUE; MICE; MICE, KNOCKOUT;

EID: 0034644009     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200007133430207     Document Type: Review

References (63)

1. Pabst R, Westermann J, Binns RM. Lymphocyte trafficking. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 3. London: Academic Press, 1998:1616-20.
2. McGhee JR. Mucosal-associated lymphoid tissue. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 3. London: Academic Press, 1998:1774-80.
3. Pringault E, ed. M cell development and function in physiology and disease. Semin Immunol 1999;11:155-224.
4. Beagley KW, Husband AJ. Intraepithelial lymphocytes: origins, distribution, and function. Crit Rev Immunol 1998;18:237-54.
5. Barrett TA, Bluestone JA. Development of TCR gamma delta iIELs. Semin Immunol 1995;7:299-305.
6. Brandtzaeg P, Farstan IN, Haraldsen G. Regional specialization in the mucosal immune system: primed cells do not always home along the same track. Immunol Today 1999;20:267-77.
7. Wu HY, Russell MW. Induction of mucosal and systemic immune responses by intranasal immunization using recombinant cholera toxic B subunit as an adjuvant. Vaccine 1998;16:286-92.
8. Klavinskis LS, Barnfield C, Gao L, Parker S. Intranasal immunization with plasmid DNA-lipid complexes elicits mucosal immunity in the female genital and rectal tracts. J Immunol 1999;162:254-62.
9. Young AJ. The physiology of lymphocyte migration through the single lymph node in vivo. Semin Immunol 1999;11:73-83.
10. Rossiter H, Alon R, Kupper TS. Selectins, T-cell rolling and inflammation. Mol Med Today 1997;3:214-22.
11. Parham P, ed. The anatomy of antigen-specific immune responses. Immunol Rev 1997;156:5-209.
12. Kelsoe G. V(D)J hypermutation and receptor revision: coloring outside the lines. Curr Opin Immunol 1999;11:70-5.
13. Tarlinton D. Germinal centers: form and function. Curr Opin Immunol 1998;10:245-51.
14. Sheriff S. Antibody-antigen complexes, three-dimensional structures. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 1. London: Academic Press, 1998:159-63.
15. Karlsen AE, Dyrberg T. Molecular mimicry between non-self, modified self and self in autoimmunity. Semin Immunol 1998;10:25-34.
16. Friedman H, Rose NR, Bendinelli M, eds. Microorganisms and autoimmune diseases. New York: Plenum, 1996.
17. Mond JJ, Lees A, Snapper CM. T cell-independent antigens type 2. Annu Rev Immunol 1995;13:655-92.
18. Zubler RH. Antigens, T dependent and independent. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 1. London: Academic Press, 1998:214-8.
19. Pisetsky DS. The immunologic properties of DNA. J Immunol 1996; 156:421-3.
20. Wagner H. Bacterial CpG DNA activates immune cells to signal infectious danger. Adv Immunol 1999;73:329-68.
21. Vanderlugt CJ, Miller SD. Epitope spreading. Curr Opin Immunol 1996;8:831-6.
22. Fairchild PJ, Pope H, Wraith DC. The nature of cryptic epitopes within the self-antigen myelin basic protein. Int Immunol 1996;8:1035-43.
23. Gapin L, Bravo de Alba Y, Casrouge A, Cabaniols JP, Kourilsky P, Kannellopoulos J. Antigen presentation by dendritic cells focuses T cell responses against immunodominant peptides: studies in the hen egg-white lysozyme (HEL) model. J Immunol 1998;160:1555-64.
24. Cox NJ, Fukuda K. Influenza. Infect Dis Clin North Am 1998;12:27-38.
25. Tunnacliffe A. CD3. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 1. London: Academic Press, 1998:465-8.
26. Kurosaki T. Genetic analysis of B cell antigen receptor signaling. Annu Rev Immunol 1999;17:555-92.
27. Lenschow DJ, Walunas TL, Bluestone JA. CD28/B7 system of T cell costimulation. Annu Rev Immunol 1996;14:233-58.
28. Grewal IS, Flavell RA. CD40 and CD154 in cell-mediated immunity. Annu Rev Immunol 1998;16:111-35.
29. Holter W, Schwarz M, Cerwenka A, Knapp W. The role of CD2 as a regulator of human T-cell cytokine production. Immunol Rev 1996;153: 107-22.
30. van Kooten C, Banchereau J. Functions of CD40 on B cells, dendritic cells and other cells. Curr Opin Immunol 1997;9:330-7.
31. Sayegh MH, Turka LA. The role of T-cell costimulatory activation pathways in transplant rejection. N Engl J Med 1998;338:1813-21.
32. Biancone L, Cantaluppi V, Camussi G. CD40-CD154 interaction in experimental and human disease. Int J Mol Med 1999;3:343-53.
33. Justement LB. The role of CD45 in signal transduction. Adv Immunol 1997;66:1-65.
34. Joseph SB, Miner KT, Croft M. Augmentation of naive, Th1 and Th2 effector CD4 responses by IL-6, IL-1 and TNF. Eur J Immunol 1998;28: 277-89.
35. Mosmann TR. Properties and functions of interleukin-10. Adv Immunol 1994;56:1-26.
36. Letterio JJ, Roberts AB. Regulation of immune responses by TGF-beta. Annu Rev Immunol 1998;16:137-61.
37. Bluestone JA. Is CTLA-4 a master switch for peripheral T cell tolerance? J Immunol 1997;158:1989-93.
38. van de Winkel JGJ, Capcl PJA, eds. Human IgG Fc receptors. Austin, Tex.: R.G. Landes, 1996.
39. Daëron M. Fc receptor biology. Annu Rev Immunol 1997;15:203-34.
40. Mosmann TR, Sad S The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 1996;17:138-46.
41. Gately MK, Renzetti LM, Magram J, et al. The interleukin-12/interleukin-12-receptor system: role in normal and pathologic immune responses. Annu Rev Immunol 1998;16:495-521.
42. Grunig G, Corry DB, Leach MW, Seymour BW, Kurup VP, Rennick DM. Interleukin-10 is a natural suppressor of cytokine production and inflammation in a murine model of allergic bronchopulmonary aspergillosis. J Exp Med 1997;185:1089-99.
43. Podack ER. Functional significance of two cytolytic pathways of cytotoxic T lymphocytes. I Leukoc Biol 1995;57:548-52.
44. Mosmann TR, Li L, Sad S. Functions of CD8 T-cell subsets secreting different cytokine patterns. Semin Immunol 1997;9:87-92.
45. Hahn S, Gehri R, Erb P. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol Rev 1995;146:57-79.
46. + T-cells. J Immunol 1997;159:2091-9.
47. Wang B, Simpson SJ, Hollander GA, Terhorst C. Development and function of T lymphocytes and natural killer cells after bone marrow transplantation of severely immunodeficient mice. Immunol Rev 1997;157:53-60.
48. Burdin N, Kronenberg M. CD1-mediated immune responses to glycolipids. Curr Opin Immunol 1999;11:326-31.
49. Burton DR. Immunoglobulin, functions. In: Delves PJ, Roitt IM, eds. Encyclopedia of immunology. 2nd ed. Vol. 3. London: Academic Press, 1998:1315-9.
50. Raghavan M, Bjorkman PJ. Fc receptors and their interactions with immunoglobulins. Annu Rev Cell Dev Biol 1996;12:181-220.
51. Cao D, Boxer LA, Petty HR. Deposition of reactive oxygen metabolites onto and within living tumor cells during neutrophil-mediated antibody-dependent cellular cytotoxicity. J Cell Physiol 1993;156:428-36.
52. Krajci P, Kvale D, Brandtzaeg P. Cloning, chromosomal localization, and linkage analysis of the gene encoding human transmembrane secretory component (the poly-Ig receptor). Adv Exp Med Biol 1995;371A:617-23.
53. Ghetie V, Ward ES. FcRn: the MHC class I-related receptor that is more than an IgG transporter. Immunol Today 1997;18:592-8.
54. Parham P, ed. Transgenic and knockout models of human disease. Immunol Rev 1999;169:5-302.
55. Falcone M, Sarvetnick N. The effect of local production of cytokines in the pathogcnesis of insulin-dependent diabetes mellitus. Clin Immunol 1999;90:2-9.
56. Akkaraju S, Canaan K, Goodnow CC. Self-reactive B cells are not eliminated or inactivated by autoantigen expressed on thyroid epithelial cell. J Exp Med 1997;186:2005-12.
57. Wang H, Shlomchik MJ. High affinity rheumatoid factor transgenic B cells are eliminated in normal mice. J Immunol 1997;159:1125-34.
58. Opelz G. Efficacy of rejection prophylaxis with OKT3 in renal transplantation. Transplantation 1995;60:1220-4.
59. Goding JW. Monoclonal antibodies: principles and practice: production and application of monoclonal antibodies in cell biology, biochemistry and immunology. 3rd ed. San Diego, Calif.: Academic Press, 1996.
60. Powers DB, Marks JD. Monovalent phagc display of Fab and scFV fusions. In: Chamow SM, Ashkenazi A, eds. Antibody fusion proteins. New York: Wiley-Liss, 1999:151-88.
61. McCafferty J, Hogenboom H, Chiswell D, eds. Antibody engineering: a practical approach. Oxford, England: IRL Press, 1996.
62. Reiter Y, Pastan I. Antibody engineering of recombinant Fv immunotoxins for improved targeting of cancer: disulfide-stabilized Fv immunotoxins. Clin Cancer Res 1996;2:245-52.
63. van de Winkel JG, Bast B, de Gast GC. Immunotherapeutic potential of bispecific antibodies. Immunol Today 1997;18:562-4.