Natural products synthesis: Enabling tools to penetrate nature's secrets of bioqenesis and biomechanism

Journal of Organic Chemistry

Volumn 76, Issue 11, 2011, Pages 4221-4259

  Williams, Robert M ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL SYNTHESIS; COMPLEX MOLECULES; ENABLING TOOLS; NATURAL PRODUCTS; NATURALLY OCCURRING; SECONDARY METABOLITES; SELECTED EXAMPLES; SYNTHETIC TECHNOLOGY; TOTAL SYNTHESIS;

METABOLITES;

BIOSYNTHESIS;

1 ACETYL 8 CARBAMOYLOXYMETHYL 3,9 EPOXY 5 FORMYL 1A,2,3,8,9,9A HEXAHYDRO 9 HYDROXY 7 METHOXY 1H AZIRINO[2,3 C][1]BENZAZOCINE ACETATE; 1 ACETYL 8ALPHA (CARBAMOYLOXYMETHYL) 3,9 EPOXY 5 FORMYL 1,1A,2,8,9,9A OCTAHYDROAZIRINO[2,3 C][1]BENZAZOCINE 7,9 DIOL ACETATE; 4 FORMYL 6,9 DIHYDROXY 14 OXA 1,11 DIAZATETRACYCLO[7.4.1.0 2,7 0 10,12]TETRADECA 2,4,6 TRIEN 8 YLMETHYLCARBAMATE; AMINO ACID DERIVATIVE; ANTINEOPLASTIC AGENT; ASPERPARALINE; BICOZAMYCIN; BREVIANAMIDE A; BREVIANAMIDE B; BREVIANAMIDE E; CYLINDROSPERMOPSIN; HISTONE DEACETYLASE INHIBITOR; INDOLE ALKALOID; JORUMYCIN; MALBRANCHEAMIDE B; MITOMYCIN C; NATURAL PRODUCT; NOTOAMIDE D; PACLITAXEL; PARAHERQUAMIDE; PARAHERQUAMIDE A; PARAHERQUAMIDE B; RENIERAMYCIN G; SPIROTRYPROSTATIN A; SPIROTRYPROSTATIN B; STEPHACIDIN A; TETRAHYDROISOQUINOLINE DERIVATIVE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VERSICOLAMIDE B; VM 55599;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ASPERGILLUS; ASYMMETRIC SYNTHESIS; BIOGENESIS; CYCLIZATION; CYCLOADDITION; DIELS ALDER REACTION; DRUG SYNTHESIS; HUMAN; MICHAEL ADDITION; NONHUMAN; OXIDATION REDUCTION REACTION; PENICILLIUM; REVIEW; STEREOCHEMISTRY; VASCULAR DISEASE; VASCULAR LEAK SYNDROME;

ANIMALS; BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; HISTONE DEACETYLASE INHIBITORS; HUMANS; ORGANIC CHEMICALS;

EID: 79958763837     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/Jo2003693     Document Type: Review

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140. Onishi, T.; Sebahar, P. R; Williams, R M. Org. Lett. 2003, 5, 3135-3137.
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144. DeMong, D. E.; Williams, R M. Tetrahedron Lett. 2001, 42 3529-3532.
145. DeMong, D. E.; Williams, R. M. J. Am. Chem. Soc. 2003, 125 8561-8565.
146. Jain, R. P.; Williams, R. M. Tetrahedron 2001, 57, 6505-6509.
147. Jain, R. P.; Williams, R M. Tetrahedron Lett. 2001, 42, 4437-4440.
148. Jain, R P.; Abrecht, B. K.; DeMong, D. E.; Williams, R M. Org. Lett. 2001, 24, 4287-4289.
149. Jain, R. P.; Williams, R M. J. Org. Chem. 2002, 67, 6361-6365.
150. Lane, J. W.; Chen, Y.; Williams, R M. J. Am. Chem. Soc. 2005, 127, 12684-12690.
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152. (b) Looper, R E.; Runnegar, M. T. C.; Williams, R. M. Tetrahedron 2006, 62, 4549-4562.
153. Looper, R E.; Williams, R. M. Angew. Chem., Int. Ed. 2004, 43, 2930-2933.
154. Looper, R E.; Runnegar, M. T. C.; Williams, R. M. Angew. Chem., Int. Ed. 2005, 44, 3879-3881.
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