Asymmetric total syntheses of (-)-jorumycin, (-)-renieramycin G, 3-epi-jorumycin, and 3-epi-renieramycin G

Journal of the American Chemical Society

Volumn 127, Issue 36, 2005, Pages 12684-12690

  Lane, Jonathan W ^a   Chen, Yuyin ^a   Williams, Robert M ^a  

^a UNIVERSITY OF COLORADO CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOLS; ANTIBIOTICS; SYNTHESIS (CHEMICAL); TOXICITY;

5-BENZYLOXY-2,4- DIMETHOXY-3-METHYL-BENZYL ALCOHOL; ANTITUMOR ANTIBIOTICS; C-3 EPI-PENTACYCLIC FRAMEWORK; STRUCTURE ACTIVITY RELATIONSHIP (SAR);

AROMATIC COMPOUNDS;

3 EPIJORUMYCIN; 3 EPIRENIERAMYCIN G; ANTINEOPLASTIC ANTIBIOTIC; JORUMYCIN; RENIERAMYCIN E; RENIERAMYCIN G; RENIERAMYCIN M; SAFRAMYCIN A; SAFRAMYCIN B; SAFRAMYCIN S; TETRAHYDROISOQUINOLINE DERIVATIVE; TRABECTEDIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CHEMICAL STRUCTURE; CRYSTALLIZATION; CYCLIZATION; DNA ALKYLATION; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION;

ANTIBIOTICS, ANTINEOPLASTIC; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR CONFORMATION; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDROISOQUINOLINES;

EID: 24744469211     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0535918     Document Type: Article

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