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Volumn 36, Issue 20, 1997, Pages 2190-2195

Biosynthesis of Taxol

Author keywords

Antitumor agents; Biosynthesis; Enzymes; Isotopic labeling; Taxol

Indexed keywords


EID: 0030725045     PISSN: 05700833     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.199721901     Document Type: Review
Times cited : (12)

References (49)
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    • a) Taxol is now a registered trademark of Bristol-Myers-Squibb; the generic name is paclitaxel; taxotère is a registered trademark of Rhône-Poulenc Rorer; its generic name is docetaxel. Because of the greater familiarity of the words taxol and taxotère, only these are used in the text in lieu of the corresponding generic names;
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    • note
    • b) There are other microtubuli-stabilizing compounds which, however, are not cytostatics. Therefore the simple equation depolymerization inhibitor = cytotoxic compound is questionable.
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    • c) Horizontal gene transfer may also have been performed the other way around, or could have even developed co-evolutively. However, since taxoids are typical plant products, the direction favored here seems to be most likely;
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.