Evidence for a structural motif in toxins and interleukin-2 that may be responsible for binding to endothelial cells and initiating vascular leak syndrome

Proceedings of the National Academy of Sciences of the United States of America

Volumn 96, Issue 7, 1999, Pages 3957-3962

  Baluna, Roxana ^a   Rizo, Josep ^b   Gordon, Brian E ^c   Ghetie, Victor ^a   Vitetta, Ellen S ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c CAROLINAS MEDICAL CENTER   (United States)

Author keywords

Cytokine; Disintegrin; Immunotoxin; Integrins

Indexed keywords

IMMUNOGLOBULIN G; IMMUNOTOXIN; INTERLEUKIN 2; PSEUDOMONAS EXOTOXIN; RICIN;

AMINO ACID SEQUENCE; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; DRUG STRUCTURE; DRUG SYNTHESIS; EDEMA; ENDOTHELIUM CELL; EXTRAVASATION; GENE DELETION; HUMAN; HUMAN TISSUE; IMMUNOTHERAPY; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; VASCULAR DISEASE;

ADP RIBOSE TRANSFERASES; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL TOXINS; BINDING SITES; CAPILLARY LEAK SYNDROME; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; EXOTOXINS; FIBRONECTINS; HUMANS; IMMUNOGLOBULIN G; IMMUNOTOXINS; INTERLEUKIN-2; MICE; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; RICIN; STRUCTURE-ACTIVITY RELATIONSHIP; UMBILICAL VEINS; VIRULENCE FACTORS;

BACTERIA (MICROORGANISMS); PSEUDOMONAS; PSEUDOMONAS EXOTOXIN;

EID: 0033616693     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.96.7.3957     Document Type: Article

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