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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 24, 2001, Pages 13595-13600

Taxol biosynthesis: Taxane 13α-hydroxylase is a cytochrome P450-dependent monooxygenase

(4) Jennewein, Stefan a Rithner, Christopher D b Williams, Robert M b Croteau, Rodney B a

a WASHINGTON STATE UNIVERSITY (United States)

b Department of Environmental and Radiological Health Sciences (United States)

Author keywords

Paclitaxel; Taxa 4(20),11(12) dien 5 ,13 diol; Taxus cuspidata; Yew

Indexed keywords

CYTOCHROME P450 OXYGENASE; PACLITAXEL; TAXA 4(20),11(12) DIEN 5ALPHA OL; TAXANE 13ALPHA HYDROXYLASE; TAXANE DERIVATIVE; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE;

ARTICLE; CATALYSIS; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ANALYSIS; ENZYME SPECIFICITY; LEPIDOPTERA; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OXYGENATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; TAXUS; YEAST;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL LINE; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; GENE EXPRESSION; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; PACLITAXEL; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; SPODOPTERA; TAXUS;

CUSPIDATA; LEPIDOPTERA; SPODOPTERA; TAXUS; TAXUS CUSPIDATA; UNIDENTIFIED BACULOVIRUS;

EID: 0035923612 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.251539398 Document Type: Article

Times cited : (202)

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