Cytochrome P450 taxadiene 5α-hydroxylase, a mechanistically unusual monooxygenase catalyzing the first oxygenation step of taxol biosynthesis

Chemistry and Biology

Volumn 11, Issue 3, 2004, Pages 379-387

  Jennewein, Stefan ^a   Long, Robert M ^a   Williams, Robert M ^b   Croteau, Rodney ^a  

^a WASHINGTON STATE UNIVERSITY   (United States)

^b Department of Ecosystem Science and Sustainability   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALKENE; CYTOCHROME P450; DITERPENE; ISOMERASE; MIXED FUNCTION OXIDASE; OXYGENASE; PACLITAXEL; TAXA 4(5),11(12)DIENE; TAXA-4(5),11(12)DIENE; TAXOID;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION REACTION; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; TAXUS;

ALKENES; AMINO ACID SEQUENCE; CATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; DITERPENES; ISOMERASES; KINETICS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; OXIDATION-REDUCTION; OXYGENASES; PACLITAXEL; SACCHAROMYCES CEREVISIAE; SEQUENCE ALIGNMENT; TAXOIDS; TAXUS;

INSECTA; INSERTION SEQUENCES; SACCHAROMYCES; SACCHAROMYCES CEREVISIAE; TAXUS;

EID: 2642518854     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2004.02.022     Document Type: Article

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