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Proceedings of the National Academy of Sciences of the United States of America

Volumn 98, Issue 4, 2001, Pages 1501-1506

Molecular cloning of a cytochrome P450 taxane 10β-hydroxylase cDNA from Taxus and functional expression in yeast

(4) Schoendorf, Anne a Rithner, Christopher D b Williams, Robert M b Croteau, Rodney B a

a WASHINGTON STATE UNIVERSITY (United States)

b Immunology and Pathology (United States)

Author keywords

Paclitaxel; Taxadien 5 acetoxy 10 ol; Taxadien 5 yl acetate; Taxol biosynthesis; Taxus cuspidata

Indexed keywords

COMPLEMENTARY DNA; CYTOCHROME P450; OXYGENASE; PACLITAXEL; TAXANE DERIVATIVE; TAXOID;

ARTICLE; CHROMATOGRAPHY; CYCLIZATION; DRUG ACETYLATION; DRUG SYNTHESIS; ENZYME ACTIVITY; HYDROXYLATION; MOLECULAR CLONING; NONHUMAN; OXYGENATION; PRIORITY JOURNAL; REACTION ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; SPECTROPHOTOMETRY; TAXUS; YEAST;

BASE SEQUENCE; BRIDGED COMPOUNDS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; PLANTS; SACCHAROMYCES CEREVISIAE; TAXOIDS;

CUSPIDATA; TAXUS; TAXUS CUSPIDATA;

EID: 0035852639 PISSN: 00278424 EISSN: None Source Type: Journal
DOI: 10.1073/pnas.98.4.1501 Document Type: Article

Times cited : (167)

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