Asperparaline a, a new paralytic alkaloid from Aspergillus japonicus JV-23

Tetrahedron Letters

Volumn 38, Issue 32, 1997, Pages 5655-5658

  Hayashi, Hideo ^a   Nishimoto, Yukifumi ^a   Nozaki, Hiroshi ^b  

^a Osaka Prefecture University   (Japan)

^b OKAYAMA UNIVERSITY OF SCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOID; ASPERGALINE A; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; ASPERGILLUS; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG TOXICITY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PARALYSIS; SILKWORM; X RAY CRYSTALLOGRAPHY;

ANIMALIA; ASPERGILLUS; ASPERGILLUS JAPONICUS; BOMBYX MORI;

EID: 0030761748     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)01231-8     Document Type: Article

References (6)

1. Identification of a strain JV-23 was carried out at Centraalbureau voor Schimmelcultures, the Netherland.
2. 13C-NMRsee Table.
3. max<120.1 ° were collected at 23 °C in the ω-2θ scan mode with a Rigaku AFC7R diffractometer (λ(CuKα)-1.54178 Å). Of the 1699 reflections collected, 1543 were judged to be observed after correction for Lorentz and polarization effect. The structure was determined by direct methods (SAPI91). Full-matrix least-squares refinement, with anisotropic temperature factors for the non-hydrogen atoms and Isotropic factors for the hydrogen atoms, converged to a final R factor of 0.045 for the 1543 reflections.
4. Yamazaki, M., Okuyama, E., Kobayashi, M., and Inoue, H., Tetrahedron Lett. 1981, 22, 135-136.
5. Whyte, A. C., Gloer, J. B., Wicklow, D. T., and Dowd, P. F., J. Nat. Prod. 1996, 59, 1093-1095.
6. Prange, T., Billion, M., Vuilhorgne, M., Pascard, C., Polonsky, J., and Moreau, S., Tetrahedron Lett. 1981, 22, 1977-1981.