-
1
-
-
0023838208
-
Antitumor activity and hematotoxicity of a new, substituted dihydrobenzoxazine, FK973, in mice
-
Shimomura, K., Manda, T., Mukumoto, S., Masuda, K., Nakamura, T., Mizota, T., Matsumoto, S., Nishigaki, F., Oku, T., Mori, J. and Shibayama, F. Antitumor activity and hematotoxicity of a new, substituted dihydrobenzoxazine, FK973, in mice. Cancer Res., 48, 1166-1172 (1988).
-
(1988)
Cancer Res.
, vol.48
, pp. 1166-1172
-
-
Shimomura, K.1
Manda, T.2
Mukumoto, S.3
Masuda, K.4
Nakamura, T.5
Mizota, T.6
Matsumoto, S.7
Nishigaki, F.8
Oku, T.9
Mori, J.10
Shibayama, F.11
-
2
-
-
0023185381
-
A new antitumor antibiotic, FR-900482 (I). Taxonomic studies on the producing strain: A new species of genus Streptomyces
-
Iwami, M., Kiyoto, S., Terano, H., Kohsaka, M., Aoki, H. and Imanaka, H. A new antitumor antibiotic, FR-900482 (I). Taxonomic studies on the producing strain: a new species of genus Streptomyces. J. Antibiot. (Tokyo), 40, 589-593 (1987).
-
(1987)
J. Antibiot. (Tokyo)
, vol.40
, pp. 589-593
-
-
Iwami, M.1
Kiyoto, S.2
Terano, H.3
Kohsaka, M.4
Aoki, H.5
Imanaka, H.6
-
3
-
-
0023185382
-
A new antitumor antibiotic, FR-900482 (II). Production, isolation, characterization and biological activity
-
Kiyoto, S., Shibata, T., Yamashita, M., Komori, T., Okuhara, M., Terano, H., Kohsaka, M. and Aoki, H. A new antitumor antibiotic, FR-900482 (II). Production, isolation, characterization and biological activity. J. Antibiot. (Tokyo), 40, 594-599 (1987).
-
(1987)
J. Antibiot. (Tokyo)
, vol.40
, pp. 594-599
-
-
Kiyoto, S.1
Shibata, T.2
Yamashita, M.3
Komori, T.4
Okuhara, M.5
Terano, H.6
Kohsaka, M.7
Aoki, H.8
-
4
-
-
0023213894
-
A new antitumor antibiotic, FR-900482 (III). Antitumor activity in transplantable experimental tumors
-
Shimomura, K., Hirai, O., Mizota, T., Matsumoto, S., Mori, J., Shibayama, F. and Kikuchi, H. A new antitumor antibiotic, FR-900482 (III). Antitumor activity in transplantable experimental tumors. J. Antibiot. (Tokyo), 40, 600-606 (1987).
-
(1987)
J. Antibiot. (Tokyo)
, vol.40
, pp. 600-606
-
-
Shimomura, K.1
Hirai, O.2
Mizota, T.3
Matsumoto, S.4
Mori, J.5
Shibayama, F.6
Kikuchi, H.7
-
5
-
-
1642266808
-
Phase I clinical and pharmacokinetic study of FK973
-
Majima, H., Hasegawa, K., Fukuoka, M., Furuse, K., Wakui, A., Furue, H., Masaoka, T., Hattori, T., Taguchi, T., Ogura, T. and Niitani, H. Phase I clinical and pharmacokinetic study of FK973. Proc. Am. Soc. Clin. Oncol., 9, 78 (1990).
-
(1990)
Proc. Am. Soc. Clin. Oncol.
, vol.9
, pp. 78
-
-
Majima, H.1
Hasegawa, K.2
Fukuoka, M.3
Furuse, K.4
Wakui, A.5
Furue, H.6
Masaoka, T.7
Hattori, T.8
Taguchi, T.9
Ogura, T.10
Niitani, H.11
-
6
-
-
0026343341
-
Phase I trial of FK973: Description of a delayed vascular leak syndrome
-
Pazdur, R., Ho, D. H., Daugherty, K., Bradner, W. T., Krakoff, I. H. and Raber, M. N. Phase I trial of FK973: description of a delayed vascular leak syndrome. Invest. New Drugs, 9, 377-382 (1991).
-
(1991)
Invest. New Drugs
, vol.9
, pp. 377-382
-
-
Pazdur, R.1
Ho, D.H.2
Daugherty, K.3
Bradner, W.T.4
Krakoff, I.H.5
Raber, M.N.6
-
7
-
-
0031979227
-
FK317; a novel substituted dihydrobenzoxazine with potent antitumor activity and without inducing vascular leak syndrome
-
Naoe, Y., Inami, M., Matsumoto, S., Nishigaki, F., Tsujimoto, S., Kawamura, I., Miyayasu, K., Manda, T. and Shimomura, K. FK317; a novel substituted dihydrobenzoxazine with potent antitumor activity and without inducing vascular leak syndrome. Cancer Chemother. Pharmacol., 42, 31-36 (1998).
-
(1998)
Cancer Chemother. Pharmacol.
, vol.42
, pp. 31-36
-
-
Naoe, Y.1
Inami, M.2
Matsumoto, S.3
Nishigaki, F.4
Tsujimoto, S.5
Kawamura, I.6
Miyayasu, K.7
Manda, T.8
Shimomura, K.9
-
8
-
-
0018949428
-
Prognostic effect of weight loss prior to chemotherapy in cancer patients
-
DeWys, W. D., Begg, C., Lavin, P. T., Band, P. R., Bennett, J. M., Bertino, J. R., Cohen, M. H., Douglass, H. O., Engstrom, P. F., Ezdinli, E. Z., Horton, J., Johnson, G. J., Moertel, C. G., Oken, M. M., Perlia, C., Rosenbaum, C., Silverstein, M. N., Skeel, R. T., Sponzo, R. W. and Tormey, D. C. Prognostic effect of weight loss prior to chemotherapy in cancer patients. Am. J. Med., 69, 491-497 (1980).
-
(1980)
Am. J. Med.
, vol.69
, pp. 491-497
-
-
DeWys, W.D.1
Begg, C.2
Lavin, P.T.3
Band, P.R.4
Bennett, J.M.5
Bertino, J.R.6
Cohen, M.H.7
Douglass, H.O.8
Engstrom, P.F.9
Ezdinli, E.Z.10
Horton, J.11
Johnson, G.J.12
Moertel, C.G.13
Oken, M.M.14
Perlia, C.15
Rosenbaum, C.16
Silverstein, M.N.17
Skeel, R.T.18
Sponzo, R.W.19
Tormey, D.C.20
more..
-
9
-
-
0021934493
-
Tumor-host metabolic interaction and cachexia
-
Lazo, P. A. Tumor-host metabolic interaction and cachexia. FEBS Lett., 187, 189-192 (1985).
-
(1985)
FEBS Lett.
, vol.187
, pp. 189-192
-
-
Lazo, P.A.1
-
10
-
-
0026181767
-
Common symptoms in patients with advanced cancer
-
Curtis, E. B., Krech, R. and Walsh, T. D. Common symptoms in patients with advanced cancer. J. Palliat. Care, 7, 25-29 (1991).
-
(1991)
J. Palliat. Care
, vol.7
, pp. 25-29
-
-
Curtis, E.B.1
Krech, R.2
Walsh, T.D.3
-
12
-
-
0016696542
-
Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure
-
Corbett, T. H., Griswold, D. P., Jr., Robert, B. J., Peckham, J. C. and Schabel, F. M., Jr. Tumor induction relationships in development of transplantable cancers of the colon in mice for chemotherapy assays, with a note on carcinogen structure. Cancer Res., 35, 2434-2439 (1975).
-
(1975)
Cancer Res.
, vol.35
, pp. 2434-2439
-
-
Corbett, T.H.1
Griswold Jr., D.P.2
Robert, B.J.3
Peckham, J.C.4
Schabel Jr., F.M.5
-
13
-
-
0025263860
-
Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice
-
Tanaka, Y., Eda, H., Tanaka, T., Udagawa, T., Ishikawa, T., Horii, I., Ishitsuka, H., Kataoka, T. and Taguchi, T. Experimental cancer cachexia induced by transplantable colon 26 adenocarcinoma in mice. Cancer Res., 50, 2290-2295 (1990).
-
(1990)
Cancer Res.
, vol.50
, pp. 2290-2295
-
-
Tanaka, Y.1
Eda, H.2
Tanaka, T.3
Udagawa, T.4
Ishikawa, T.5
Horii, I.6
Ishitsuka, H.7
Kataoka, T.8
Taguchi, T.9
-
14
-
-
0019351587
-
Current results of the screening program at the Division of Cancer Treatment, National Cancer Institute
-
Goldin, A., Venditti, J. M., Macdonald, J. S., Muggia, F. M., Henney, J. E. and Devita, V. T., Jr. Current results of the screening program at the Division of Cancer Treatment, National Cancer Institute. Eur. J. Cancer, 17, 129-142 (1981).
-
(1981)
Eur. J. Cancer
, vol.17
, pp. 129-142
-
-
Goldin, A.1
Venditti, J.M.2
Macdonald, J.S.3
Muggia, F.M.4
Henney, J.E.5
Devita Jr., V.T.6
-
15
-
-
0024363349
-
Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses
-
Tashiro, T., Inaba, M., Kobayashi, T., Sakurai, Y., Maruo, K., Ohnishi, Y., Ueyama, Y. and Nomura, T. Responsiveness of human lung cancer/nude mouse to antitumor agents in a model using clinically equivalent doses. Cancer Chemother. Pharmacol., 24, 187-192 (1989).
-
(1989)
Cancer Chemother. Pharmacol.
, vol.24
, pp. 187-192
-
-
Tashiro, T.1
Inaba, M.2
Kobayashi, T.3
Sakurai, Y.4
Maruo, K.5
Ohnishi, Y.6
Ueyama, Y.7
Nomura, T.8
-
16
-
-
0026689535
-
Evidence for the involvement of interleukin 6 in experimental cancer cachexia
-
Strassmann, G., Fong, M., Kenney, J. S. and Jacob, C. O. Evidence for the involvement of interleukin 6 in experimental cancer cachexia. J. Clin. Invest., 89, 1681-1684 (1992).
-
(1992)
J. Clin. Invest.
, vol.89
, pp. 1681-1684
-
-
Strassmann, G.1
Fong, M.2
Kenney, J.S.3
Jacob, C.O.4
-
17
-
-
0026532492
-
Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia
-
Strassmann, G., Jacob, C. O., Evans, R., Beall, D. and Fong, M. Mechanisms of experimental cancer cachexia. Interaction between mononuclear phagocytes and colon-26 carcinoma and its relevance to IL-6-mediated cancer cachexia. J. Immunol., 148, 3674-3678 (1992).
-
(1992)
J. Immunol.
, vol.148
, pp. 3674-3678
-
-
Strassmann, G.1
Jacob, C.O.2
Evans, R.3
Beall, D.4
Fong, M.5
-
18
-
-
0027196193
-
Mechanisms of experimental cancer cachexia: Local involvement of IL-1 in colon-26 tumor
-
Strassmann, G., Masui, Y., Chizzonite, R. and Fong, M. Mechanisms of experimental cancer cachexia: local involvement of IL-1 in colon-26 tumor. J. Immunol., 150, 2341-2345 (1993).
-
(1993)
J. Immunol.
, vol.150
, pp. 2341-2345
-
-
Strassmann, G.1
Masui, Y.2
Chizzonite, R.3
Fong, M.4
-
19
-
-
0031895855
-
Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice
-
Yamamoto, N., Kawamura, I., Nishigaki, F., Tsujimoto, S., Naoe, Y., Inami, M., Lacey, E., Manda, T. and Shimomura, K. Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice. Anticancer Res., 18, 139-144 (1998).
-
(1998)
Anticancer Res.
, vol.18
, pp. 139-144
-
-
Yamamoto, N.1
Kawamura, I.2
Nishigaki, F.3
Tsujimoto, S.4
Naoe, Y.5
Inami, M.6
Lacey, E.7
Manda, T.8
Shimomura, K.9
-
20
-
-
84920320702
-
Injection of oligonucleotides to NFκB binding site specifically inhibited cachexia in a mouse tumor model
-
in press
-
Kawamura, I., Morishita, R., Tomita, N., Lacey, E., Aketa, M., Tsujimoto, S., Manda, T., Tomoi, M., Kida, I., Higaki, J., Kaneda, Y., Shimomura, K. and Ogihara, T. Injection of oligonucleotides to NFκB binding site specifically inhibited cachexia in a mouse tumor model. Gene Ther., 5 (1998), in press.
-
(1998)
Gene Ther.
, vol.5
-
-
Kawamura, I.1
Morishita, R.2
Tomita, N.3
Lacey, E.4
Aketa, M.5
Tsujimoto, S.6
Manda, T.7
Tomoi, M.8
Kida, I.9
Higaki, J.10
Kaneda, Y.11
Shimomura, K.12
Ogihara, T.13
-
21
-
-
0032448967
-
FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice
-
Naoe, Y., Inami, M., Matsumoto, S., Takagaki, S., Fujiwara, T., Yamazaki, S., Kawamura, I., Nishigaki, F., Tsujimoto, S., Manda T. and Shimomura, K. FK317, a novel substituted dihydrobenzoxazine, exhibits potent antitumor activity against human tumor xenografts in nude mice. Jpn. J. Cancer Res., 89, 1306-1317 (1998).
-
(1998)
Jpn. J. Cancer Res.
, vol.89
, pp. 1306-1317
-
-
Naoe, Y.1
Inami, M.2
Matsumoto, S.3
Takagaki, S.4
Fujiwara, T.5
Yamazaki, S.6
Kawamura, I.7
Nishigaki, F.8
Tsujimoto, S.9
Manda, T.10
Shimomura, K.11
|