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0001595852
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Otera, J. Chem. Rev. 1993, 93, 1449-1470. The isothiocyanate catalyst pictured below was used: Equation presented
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(b) Otera, J. Chem. Rev. 1993, 93, 1449-1470. The isothiocyanate catalyst pictured below was used: Equation presented
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33
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0000692328
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34
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84858094703
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The E/Z configuration of oxindole-bound olefin in 5 and its derivatives is not known, but presumed to be as depicted based on known trends of α,β-unsaturated amides.
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The E/Z configuration of oxindole-bound olefin in 5 and its derivatives is not known, but presumed to be as depicted based on known trends of α,β-unsaturated amides.
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36
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34547163974
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The formation of 18 (12-epi-2) can be attributed to the basicity of the reaction conditions. This stereocenter has been shown to be labile, e.g., ref 4e.
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The formation of 18 (12-epi-2) can be attributed to the basicity of the reaction conditions. This stereocenter has been shown to be labile, e.g., ref 4e.
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37
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34547193289
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The structure of the nucleophile generated by energy-minimized Chem3D calculations.
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The structure of the nucleophile generated by energy-minimized Chem3D calculations.
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