The effect of grapefruit juice on drug disposition

Expert Opinion on Drug Metabolism and Toxicology

Volumn 7, Issue 3, 2011, Pages 267-286

  Hanley, Michael J ^a   Cancalon, Paul ^b   Widmer, Wilbur W ^c   Greenblatt, David J ^a  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Florida Department of Citrus   (United States)

^c U S DEPARTMENT OF AGRICULTURE   (United States)

Author keywords

CYP3A; drug fruit juice interactions; flavonoids; furanocoumarins; grapefruit; OATP; P glycoprotein

Indexed keywords

ANTIDIABETIC AGENT; ANTIHISTAMINIC AGENT; ANTIINFECTIVE AGENT; ANTINEOPLASTIC AGENT; CAFFEINE; CARDIOVASCULAR AGENT; CENTRAL NERVOUS SYSTEM AGENTS; CHLORZOXAZONE; CISAPRIDE; COUMARIN DERIVATIVE; CYTOCHROME P450; CYTOCHROME P450 3A; DEXTROMETHORPHAN; DRUG METABOLIZING ENZYME; ESTERASE; FLAVONOID; GLYCOPROTEIN P; HORMONE; IMMUNOSUPPRESSIVE AGENT; MONTELUKAST; OPIATE; ORGANIC ANION TRANSPORTER; PROTON PUMP INHIBITOR; QUERCETIN; SCOPOLAMINE; SILDENAFIL; STEROID; SULFOTRANSFERASE; THEOPHYLLINE; UNINDEXED DRUG;

AREA UNDER THE CURVE; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG DISPOSITION; DRUG HYDROXYLATION; DRUG METABOLISM; FOOD COMPOSITION; FOOD DRUG INTERACTION; GRAPEFRUIT JUICE; HUMAN; INTESTINE CELL; LIVER MICROSOME METABOLISM; MEDLINE; NONHUMAN; REVIEW; ULTRAVIOLET RADIATION;

ANIMALS; BEVERAGES; CITRUS PARADISI; FOOD-DRUG INTERACTIONS; HUMANS; PHARMACOKINETICS;

CITRUS X PARADISI;

EID: 79951887829     PISSN: 17425255     EISSN: None     Source Type: Journal    
DOI: 10.1517/17425255.2011.553189     Document Type: Review

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