Identification of 6′,7′-dihydroxybergamottin, a cytochrome P450 inhibitor, in grapefruit juice

Drug Metabolism and Disposition

Volumn 24, Issue 12, 1996, Pages 1287-1290

  Edwards, David J ^a   Bellevue III, Frank H ^a   Woster, Patrick M ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6',7' DIHYDROXYBERGAMOTTIN; AURANTIIN; CYCLOSPORIN; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; FELODIPINE; FUROCOUMARIN DERIVATIVE; KETOCONAZOLE; MIDAZOLAM; NIFEDIPINE; NITRENDIPINE; TERFENADINE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DRUG ISOLATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME INHIBITION; FRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INTRAVENOUS DRUG ADMINISTRATION; LIVER MICROSOME; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BEVERAGES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, THIN LAYER; CITRUS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; METHYLENE CHLORIDE; MICROSOMES, LIVER; OXIDOREDUCTASES, N-DEMETHYLATING; PSORALENS; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; CITRUS X PARADISI;

EID: 0030482468     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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