Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4

British Journal of Pharmacology

Volumn 130, Issue 6, 2000, Pages 1369-1377

  Ohnishi, Ayako ^a   Matsuo, Hirotami ^a   Yamada, Shiho ^a   Takanaga, Hitomi ^a   Morimoto, Satoshi ^a   Shoyama, Yukihiro ^a   Ohtani, Hisakazu ^a   Sawada, Yasufumi ^a  

^a KYUSHU UNIVERSITY   (Japan)

Author keywords

CYP3A4; DHBG; Furanocoumarins; GFJ component; P gp; VBL transport

Indexed keywords

ACETIC ACID ETHYL ESTER; BERGAMOTTIN; BERGAPTEN; BERGAPTOL; CYCLOSPORIN A; CYTOCHROME P450 3A4; CYTOCHROME P450 INHIBITOR; FC 726; FUROCOUMARIN DERIVATIVE; TRITIUM; UNCLASSIFIED DRUG; VINBLASTINE;

ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; DRUG TRANSPORT; DRUG UPTAKE; ENZYME ACTIVITY; FRUIT JUICE; HUMAN; HUMAN CELL; ISOTOPE LABELING; PRIORITY JOURNAL;

EID: 0033913305     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0703433     Document Type: Article

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