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Volumn 52, Issue 2, 1997, Pages 139-145

Effects of grapefruit juice ingestion - Pharmacokinetics and haemodynamics of intravenously and orally administered felodipine in healthy men

Author keywords

Dietary interaction; Felodipine; Flavonoids; grapefruit juice; pharmacodynamics; pharmacokinetics

Indexed keywords

4 (2,3 DICHLOROPHENYL) 2,6 DIMETHYL 3,5 PYRIDINEDICARBOXYLIC ACID ETHYL METHYL ESTER; DRUG METABOLITE; FELODIPINE; WATER;

EID: 0031001463     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050263     Document Type: Article
Times cited : (162)

References (29)
  • 1
    • 0028828376 scopus 로고
    • Relationship between time of intake of grapefruit juice and its effects on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects
    • Lundahl J, Regårdh CG, Edgar B, Johnsson G (1995) Relationship between time of intake of grapefruit juice and its effects on pharmacokinetics and pharmacodynamics of felodipine in healthy subjects. Eur J Clin Pharmacol 49: 61-67
    • (1995) Eur J Clin Pharmacol , vol.49 , pp. 61-67
    • Lundahl, J.1    Regårdh, C.G.2    Edgar, B.3    Johnsson, G.4
  • 2
    • 0023588109 scopus 로고
    • Identification of glucocorticoid-inducible cytochrome P-450 in the intestinal mucosa of rat and man
    • Watkins P, Wrighton S, Schuetz E, Molowa D, Guzelian P (1987) Identification of glucocorticoid-inducible cytochrome P-450 in the intestinal mucosa of rat and man. J Clin Invest 80: 1029-1036
    • (1987) J Clin Invest , vol.80 , pp. 1029-1036
    • Watkins, P.1    Wrighton, S.2    Schuetz, E.3    Molowa, D.4    Guzelian, P.5
  • 3
    • 0024593072 scopus 로고
    • Characterization of human microsomal cytochrome P-450 enzymes
    • Guengerich FP (1989) Characterization of human microsomal cytochrome P-450 enzymes. Ann Rev Pharmacol Toxicol 29: 241-264
    • (1989) Ann Rev Pharmacol Toxicol , vol.29 , pp. 241-264
    • Guengerich, F.P.1
  • 4
    • 0025344378 scopus 로고
    • Cytochrome P450 isoenzymes, epoxide, hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues
    • De Waziers I, Cugnenc PH, Yang CS, Leroux JP, Beaune PH (1990) Cytochrome P450 isoenzymes, epoxide, hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues. J Pharmacol Exp Ther 253: 387-394
    • (1990) J Pharmacol Exp Ther , vol.253 , pp. 387-394
    • De Waziers, I.1    Cugnenc, P.H.2    Yang, C.S.3    Leroux, J.P.4    Beaune, P.H.5
  • 5
    • 0026464616 scopus 로고
    • Identification of rifampicin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB (1992) Identification of rifampicin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 90: 1871-1878
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 6
  • 11
    • 0023907328 scopus 로고
    • Nisoldipine: Kinetics and effects on blood pressure and heart rate in patients with liver cirrhosis after intravenous and oral administration
    • Van Harten J, Van Brummelen P, Wilson JHP, Lodewijks MTM, Breimer DD (1988) Nisoldipine: kinetics and effects on blood pressure and heart rate in patients with liver cirrhosis after intravenous and oral administration. Eur J Clin Pharmacol 34: 387-394
    • (1988) Eur J Clin Pharmacol , vol.34 , pp. 387-394
    • Van Harten, J.1    Van Brummelen, P.2    Wilson, J.H.P.3    Lodewijks, M.T.M.4    Breimer, D.D.5
  • 12
    • 0021672555 scopus 로고
    • Determination of felodipine in plasma by capillary gas chromatography with electron capture detection
    • Ahnoff (1984) Determination of felodipine in plasma by capillary gas chromatography with electron capture detection. J Pharm Biomed Analysis 2: 519-526
    • (1984) J Pharm Biomed Analysis , vol.2 , pp. 519-526
    • Ahnoff1
  • 13
    • 0028820208 scopus 로고    scopus 로고
    • Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine
    • Wu C-Y, Benet L, Herbert M, Gupta S, Rowland M, Gomez D, Wacher V (1996) Differentiation of absorption and first-pass gut and hepatic metabolism in humans: Studies with cyclosporine. Clin Pharmacol Ther 56: 492-497
    • (1996) Clin Pharmacol Ther , vol.56 , pp. 492-497
    • Wu, C.-Y.1    Benet, L.2    Herbert, M.3    Gupta, S.4    Rowland, M.5    Gomez, D.6    Wacher, V.7
  • 14
    • 0023182481 scopus 로고
    • Pharmacokinetic and pharamacodynamic studies of felodipine in healthy subjects after various single. oral and intravenous doses
    • Edgar B, Regårdh CG, Lundborg P, Romare S, Nyberg G, Rönn O (1987) Pharmacokinetic and pharamacodynamic studies of felodipine in healthy subjects after various single. oral and intravenous doses. Biopharma Drug Dispos 8: 235 248
    • (1987) Biopharma Drug Dispos , vol.8 , pp. 235248
    • Edgar, B.1    Regårdh, C.G.2    Lundborg, P.3    Romare, S.4    Nyberg, G.5    Rönn, O.6
  • 17
  • 18
    • 7144219747 scopus 로고
    • Implication for clinical dosage management of steady-state cylosporine a and metabolite pharmacokinetics in renal patients
    • San Diego
    • Proppe D, Hoch O, Visser K, Maclean AJ (1995) Implication for clinical dosage management of steady-state cylosporine a and metabolite pharmacokinetics in renal patients. Abstract of the ASCPT meeting, San Diego, PII-112: 191
    • (1995) Abstract of the ASCPT Meeting , vol.PII-112 , pp. 191
    • Proppe, D.1    Hoch, O.2    Visser, K.3    Maclean, A.J.4
  • 21
    • 0028641539 scopus 로고
    • Inhibition of 17-beta-estradiol by grapefruit juice in ovariectomized women
    • Schubert W, Cullberg G, Edgar B, Hedner T (1994) Inhibition of 17-beta-estradiol by grapefruit juice in ovariectomized women. Maturitas 20: 155-163
    • (1994) Maturitas , vol.20 , pp. 155-163
    • Schubert, W.1    Cullberg, G.2    Edgar, B.3    Hedner, T.4
  • 23
    • 0013521181 scopus 로고
    • Pharmacokinetics and cardiac effects of terfenadine in poor metabolizers receiving terfenadine concomitant grapefruit juice
    • San Diego.
    • Honig P, Wortham D, Lazarev A, Cantilena LR (1995) Pharmacokinetics and cardiac effects of terfenadine in poor metabolizers receiving terfenadine concomitant grapefruit juice. Abstract of the ASCPT meeting, San Diego. PII-87: 185
    • (1995) Abstract of the ASCPT Meeting , vol.PII-87 , pp. 185
    • Honig, P.1    Wortham, D.2    Lazarev, A.3    Cantilena, L.R.4
  • 24
    • 0027510377 scopus 로고
    • Inhibitory effect of grapefruit juice and its bitter principal, naringenin. on CYP1A2 dependent metabolism of caffeine in man
    • Fuhr U, Klittich K, Staib H (1993) Inhibitory effect of grapefruit juice and its bitter principal, naringenin. on CYP1A2 dependent metabolism of caffeine in man. Br J Clin Pharmacol 35: 431-436
    • (1993) Br J Clin Pharmacol , vol.35 , pp. 431-436
    • Fuhr, U.1    Klittich, K.2    Staib, H.3
  • 25
    • 0028218139 scopus 로고
    • Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers
    • Merkel U, Sigusch H, Hoffmann A (1994) Grapefruit juice inhibits 7-hydroxylation of coumarin in healthy volunteers. Eur J Clin Pharmacol 46: 175-177
    • (1994) Eur J Clin Pharmacol , vol.46 , pp. 175-177
    • Merkel, U.1    Sigusch, H.2    Hoffmann, A.3
  • 26
    • 0021239476 scopus 로고
    • Imipramine-cimetidine interaction: Impairment of clearance and enhanced absolute bioavailability
    • Abernethy D, Greenblatt D, Shader R (1984) Imipramine-cimetidine interaction: Impairment of clearance and enhanced absolute bioavailability. J Pharm Exp Ther 3: 702-705
    • (1984) J Pharm Exp Ther , vol.3 , pp. 702-705
    • Abernethy, D.1    Greenblatt, D.2    Shader, R.3
  • 28
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme M, Warbasse L, Edwards D (1995) Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharm Ther 57: 485-491
    • (1995) Clin Pharm Ther , vol.57 , pp. 485-491
    • Ducharme, M.1    Warbasse, L.2    Edwards, D.3
  • 29
    • 0025613077 scopus 로고
    • Pharmacokinetics and haemodynamics and diuretic natriuretic effects of felodipine administered as an extended-release tablet
    • Hasselgren B, Rönn O, Edgar B, Johansson P, Wall B (1990) Pharmacokinetics and haemodynamics and diuretic natriuretic effects of felodipine administered as an extended-release tablet. Card Drug Ther 4: 1495-1500
    • (1990) Card Drug Ther , vol.4 , pp. 1495-1500
    • Hasselgren, B.1    Rönn, O.2    Edgar, B.3    Johansson, P.4    Wall, B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.