Grapefruit juice increases oral nimodipine bioavailability

International Journal of Clinical Pharmacology and Therapeutics

Volumn 36, Issue 3, 1998, Pages 126-132

  Fuhr, U ^a   Maier Bruggemann A ^b   Blume, H ^c   Muck W ^c   Unger, S ^c   Kuhlmann, J ^c   Huschka, C ^b   Zaigler, M ^a   Rietbrock, S ^a   Staib, A M ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c BAYER AG   (Germany)

Author keywords

CYP3A4; Cytochrome P450; Grapefruit juice; Naringenin; Naringin; Nimodipine; Pharmacokinetic interaction

Indexed keywords

CALCIUM CHANNEL BLOCKING AGENT; DIHYDROPYRIDINE DERIVATIVE; NIMODIPINE;

AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CROSSOVER PROCEDURE; DRUG BIOAVAILABILITY; FRUIT JUICE; HUMAN; HUMAN EXPERIMENT; MALE; ORAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ADULT; ANALYSIS OF VARIANCE; ANTIOXIDANTS; AREA UNDER CURVE; BEVERAGES; BIOLOGICAL AVAILABILITY; CALCIUM CHANNEL BLOCKERS; CHROMATOGRAPHY, GAS; CITRUS; CONFIDENCE INTERVALS; CROSS-OVER STUDIES; FLAVANONES; FLAVONOIDS; FOOD-DRUG INTERACTIONS; HEMODYNAMIC PROCESSES; HUMANS; MALE; NIMODIPINE; REFERENCE VALUES; WATER;

EID: 2642682403     PISSN: 09461965     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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