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Volumn 87, Issue 4, 2008, Pages 863-871

Further characterization of a furanocoumarin-free grapefruit juice on drug disposition: Studies with cyclosporine

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOSPORIN; FUROCOUMARIN DERIVATIVE; GLYCOPROTEIN P INHIBITOR;

EID: 42249088111     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/87.4.863     Document Type: Article
Times cited : (50)

References (47)
  • 2
    • 0242469224 scopus 로고    scopus 로고
    • The effects of fruit juices on drug disposition: A new model for drug interactions
    • Dresser GK, Bailey DG. The effects of fruit juices on drug disposition: a new model for drug interactions. Eur J Clin Invest 2003;33:10-6.
    • (2003) Eur J Clin Invest , vol.33 , pp. 10-16
    • Dresser, G.K.1    Bailey, D.G.2
  • 3
    • 23644436684 scopus 로고    scopus 로고
    • Undesirable effects of citrus juice on the pharmacokinetics of drugs: Focus on recent studies
    • Saito M, Hirata-Koizumi M, Matsumoto M, Urano T, Hasegawa R. Undesirable effects of citrus juice on the pharmacokinetics of drugs: focus on recent studies. Drug Saf 2005;28:677-94.
    • (2005) Drug Saf , vol.28 , pp. 677-694
    • Saito, M.1    Hirata-Koizumi, M.2    Matsumoto, M.3    Urano, T.4    Hasegawa, R.5
  • 4
    • 34249875093 scopus 로고    scopus 로고
    • Clinical relevance of the small intestine as an organ of drug elimination: Drug-fruit juice interactions. Expert Opin Drug Metab
    • Paine MF, Oberlies NH. Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions. Expert Opin Drug Metab Toxicol 2007;3:67-80.
    • (2007) Toxicol , vol.3 , pp. 67-80
    • Paine, M.F.1    Oberlies, N.H.2
  • 5
    • 0026464616 scopus 로고
    • Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
    • Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992;90:1871-8.
    • (1992) J Clin Invest , vol.90 , pp. 1871-1878
    • Kolars, J.C.1    Schmiedlin-Ren, P.2    Schuetz, J.D.3    Fang, C.4    Watkins, P.B.5
  • 6
    • 0031445547 scopus 로고    scopus 로고
    • Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism
    • Paine MF, Khalighi M, Fisher JM, et al. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. J Pharmacol Exp Ther 1997;283:1552-62.
    • (1997) J Pharmacol Exp Ther , vol.283 , pp. 1552-1562
    • Paine, M.F.1    Khalighi, M.2    Fisher, J.M.3
  • 7
    • 0030982634 scopus 로고    scopus 로고
    • Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression
    • Lown KS, Bailey DG, Fontana RJ, et al. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. J Clin Invest 1997;99:2545-53.
    • (1997) J Clin Invest , vol.99 , pp. 2545-2553
    • Lown, K.S.1    Bailey, D.G.2    Fontana, R.J.3
  • 8
    • 0030868487 scopus 로고    scopus 로고
    • Specific CYP3A4 inhibitors in grapefruit juice: Furocoumarin dimers as components of drug interaction
    • Fukuda K, Ohta T, Oshima Y, Ohashi N, Yoshikawa M, Yamazoe Y. Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction. Pharmacogenetics 1997;7:391-6.
    • (1997) Pharmacogenetics , vol.7 , pp. 391-396
    • Fukuda, K.1    Ohta, T.2    Oshima, Y.3    Ohashi, N.4    Yoshikawa, M.5    Yamazoe, Y.6
  • 9
    • 0030696487 scopus 로고    scopus 로고
    • Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins
    • Schmiedlin-Ren P, Edwards DJ, Fitzsimmons ME, et al. Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins. Drug Metab Dispos 1997;25:1228-33.
    • (1997) Drug Metab Dispos , vol.25 , pp. 1228-1233
    • Schmiedlin-Ren, P.1    Edwards, D.J.2    Fitzsimmons, M.E.3
  • 11
    • 0342868292 scopus 로고    scopus 로고
    • Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity
    • Guo LQ, Fukuda K, Ohta T, Yamazoe Y. Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity. Drug Metab Dispos 2000;28:766-71.
    • (2000) Drug Metab Dispos , vol.28 , pp. 766-771
    • Guo, L.Q.1    Fukuda, K.2    Ohta, T.3    Yamazoe, Y.4
  • 12
  • 13
    • 4644267926 scopus 로고    scopus 로고
    • Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties
    • Paine MF, Criss AB, Watkins PB. Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties. Drug Metab Dispos 2004;32:1146-53.
    • (2004) Drug Metab Dispos , vol.32 , pp. 1146-1153
    • Paine, M.F.1    Criss, A.B.2    Watkins, P.B.3
  • 14
    • 0034948448 scopus 로고    scopus 로고
    • Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats
    • Mohri K, Uesawa Y. Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats. Pharm Res 2001;18:177-82.
    • (2001) Pharm Res , vol.18 , pp. 177-182
    • Mohri, K.1    Uesawa, Y.2
  • 16
    • 33745159659 scopus 로고    scopus 로고
    • A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction
    • Paine MF, Widmer WW, Hart HL, et al. A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction. Am J Clin Nutr 2006;83:1097-105.
    • (2006) Am J Clin Nutr , vol.83 , pp. 1097-1105
    • Paine, M.F.1    Widmer, W.W.2    Hart, H.L.3
  • 19
    • 0028963036 scopus 로고
    • Effect of grapefruit juice on blood cyclosporin concentration
    • Yee GC, Stanley DL, Pessa LJ, et al. Effect of grapefruit juice on blood cyclosporin concentration. Lancet 1995;345:955-6.
    • (1995) Lancet , vol.345 , pp. 955-956
    • Yee, G.C.1    Stanley, D.L.2    Pessa, L.J.3
  • 20
    • 0029055363 scopus 로고
    • Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
    • Ducharme MP, Warbasse LH, Edwards DJ. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharmacol Ther 1995;57:485-91.
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 485-491
    • Ducharme, M.P.1    Warbasse, L.H.2    Edwards, D.J.3
  • 21
    • 0029890499 scopus 로고    scopus 로고
    • Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients
    • Min DI, Ku YM, Perry PJ, et al. Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients. Transplantation 1996;62:123-5.
    • (1996) Transplantation , vol.62 , pp. 123-125
    • Min, D.I.1    Ku, Y.M.2    Perry, P.J.3
  • 22
    • 0031784578 scopus 로고    scopus 로고
    • Effect of grapefruit juice on the pharmacokinetics of microemulsion cyclosporine and its metabolite in healthy volunteers: Does the formulation difference matter?
    • Ku YM, Min DI, Flanigan M. Effect of grapefruit juice on the pharmacokinetics of microemulsion cyclosporine and its metabolite in healthy volunteers: does the formulation difference matter? J Clin Pharmacol 1998;38:959-65.
    • (1998) J Clin Pharmacol , vol.38 , pp. 959-965
    • Ku, Y.M.1    Min, D.I.2    Flanigan, M.3
  • 24
    • 0032763895 scopus 로고    scopus 로고
    • Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities
    • Dantzig AH, Shepard RL, Law KL, et al. Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities J Pharmacol Exp Ther 1999;290:854-62.
    • (1999) J Pharmacol Exp Ther , vol.290 , pp. 854-862
    • Dantzig, A.H.1    Shepard, R.L.2    Law, K.L.3
  • 25
    • 1342323340 scopus 로고    scopus 로고
    • Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir
    • Mouly SJ, Paine MF, Watkins PB. Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir. J Pharmacol Exp Ther 2004;308:941-8.
    • (2004) J Pharmacol Exp Ther , vol.308 , pp. 941-948
    • Mouly, S.J.1    Paine, M.F.2    Watkins, P.B.3
  • 27
    • 14344258321 scopus 로고    scopus 로고
    • Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition
    • Paine MF, Criss AB, Watkins PB. Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition. J Pharmacol Exp Ther 2005;312:1151-60.
    • (2005) J Pharmacol Exp Ther , vol.312 , pp. 1151-1160
    • Paine, M.F.1    Criss, A.B.2    Watkins, P.B.3
  • 28
    • 0038665209 scopus 로고
    • Use of a simple solvent optimization program to improve separation of limonin in citrus juices
    • Shaw PE. Use of a simple solvent optimization program to improve separation of limonin in citrus juices. J Chromatogr Sci 1986;24:364-6.
    • (1986) J Chromatogr Sci , vol.24 , pp. 364-366
    • Shaw, P.E.1
  • 29
    • 0040485348 scopus 로고    scopus 로고
    • Analysis of limonin and flavonoids in citrus juices and byproduct extracts by direct injection and in-line samples clean-up
    • Berhow MA, Hasegawa S, Manners GD, eds, Washington, DC: American Chemical Society
    • Widmer WW, Haun C. Analysis of limonin and flavonoids in citrus juices and byproduct extracts by direct injection and in-line samples clean-up. In: Berhow MA, Hasegawa S, Manners GD, eds. Citrus limonoids, functional chemicals in agriculture and food. Washington, DC: American Chemical Society, 2000:60-72.
    • (2000) Citrus limonoids, functional chemicals in agriculture and food , pp. 60-72
    • Widmer, W.W.1    Haun, C.2
  • 30
    • 23744447225 scopus 로고    scopus 로고
    • One tangerine/grapefruit hybrid (tangelo) contains trace amounts of furanocoumarins at a level too low to be associated with grapefruit/drug interactions
    • Widmer W. One tangerine/grapefruit hybrid (tangelo) contains trace amounts of furanocoumarins at a level too low to be associated with grapefruit/drug interactions. J Food Sci 2005;70:C419-22.
    • (2005) J Food Sci , vol.70
    • Widmer, W.1
  • 31
    • 0001435704 scopus 로고
    • Characterization of orange juice (Citrus sinensis) by polymethoxylated flavones
    • Ooghe WC, Ooghe SJ, Detavernier CM, Huyghebaert A. Characterization of orange juice (Citrus sinensis) by polymethoxylated flavones. J Agric Food Chem 1992;42:2191-5.
    • (1992) J Agric Food Chem , vol.42 , pp. 2191-2195
    • Ooghe, W.C.1    Ooghe, S.J.2    Detavernier, C.M.3    Huyghebaert, A.4
  • 32
    • 0024085610 scopus 로고
    • C-18 solid-phase isolation and high-performance liquid-chromatography ultraviolet diode-array determination of fully methoxylated flavones in citrus juices
    • Sendra JM, Navarro JL, Izquierdo L. C-18 solid-phase isolation and high-performance liquid-chromatography ultraviolet diode-array determination of fully methoxylated flavones in citrus juices. J Chromatogr Sci 1988;26:443-8.
    • (1988) J Chromatogr Sci , vol.26 , pp. 443-448
    • Sendra, J.M.1    Navarro, J.L.2    Izquierdo, L.3
  • 33
    • 0033913305 scopus 로고    scopus 로고
    • Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4
    • Ohnishi A, Matsuo H, Yamada S, et al. Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4. Br J Pharmacol 2000;130:1369-77.
    • (2000) Br J Pharmacol , vol.130 , pp. 1369-1377
    • Ohnishi, A.1    Matsuo, H.2    Yamada, S.3
  • 34
    • 0034029597 scopus 로고    scopus 로고
    • Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4
    • Takanaga H, Ohnishi A, Yamada S, et al. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol Exp Ther 2000;293:230-6.
    • (2000) J Pharmacol Exp Ther , vol.293 , pp. 230-236
    • Takanaga, H.1    Ohnishi, A.2    Yamada, S.3
  • 35
    • 34247257725 scopus 로고    scopus 로고
    • Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells
    • Mertens-Talcott SU, De Castro WV, Manthey JA, Derendorf H, Butterweck V. Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells. J Agric Food Chem 2007;55:2563-8.
    • (2007) J Agric Food Chem , vol.55 , pp. 2563-2568
    • Mertens-Talcott, S.U.1    De Castro, W.V.2    Manthey, J.A.3    Derendorf, H.4    Butterweck, V.5
  • 36
    • 0742289647 scopus 로고    scopus 로고
    • Food-drug interaction: Grapefruit juice augments drug bioavailability - mechanism, extent and relevance
    • Dahan A, Altman H. Food-drug interaction: grapefruit juice augments drug bioavailability - mechanism, extent and relevance. Eur J Clin Nutr 2004;58:1-9.
    • (2004) Eur J Clin Nutr , vol.58 , pp. 1-9
    • Dahan, A.1    Altman, H.2
  • 37
    • 0035145184 scopus 로고    scopus 로고
    • Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients
    • Bistrup C, Nielsen FT, Jeppesen UE, Dieperink H. Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients. Nephrol Dial Transplant 2001;16:373-7.
    • (2001) Nephrol Dial Transplant , vol.16 , pp. 373-377
    • Bistrup, C.1    Nielsen, F.T.2    Jeppesen, U.E.3    Dieperink, H.4
  • 38
    • 10844279077 scopus 로고    scopus 로고
    • Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux
    • Honda Y, Ushigome F, Koyabu N, et al. Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. Br J Pharmacol 2004;143:856-64.
    • (2004) Br J Pharmacol , vol.143 , pp. 856-864
    • Honda, Y.1    Ushigome, F.2    Koyabu, N.3
  • 39
    • 35348973560 scopus 로고    scopus 로고
    • Grapefruit juice-drug interactions: Grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells
    • de Castro WV, Mertens-Talcott S, Derendorf H, Butterweck V. Grapefruit juice-drug interactions: grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells. J Pharm Sci 2007;96:2808-17.
    • (2007) J Pharm Sci , vol.96 , pp. 2808-2817
    • de Castro, W.V.1    Mertens-Talcott, S.2    Derendorf, H.3    Butterweck, V.4
  • 40
    • 1442321728 scopus 로고    scopus 로고
    • 6′,7′- Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein
    • Edwards DJ, Fitzsimmons ME, Schuetz EG, et al. 6′,7′- Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein. Clin Pharmacol Ther 1999;65:237-44.
    • (1999) Clin Pharmacol Ther , vol.65 , pp. 237-244
    • Edwards, D.J.1    Fitzsimmons, M.E.2    Schuetz, E.G.3
  • 41
    • 0036159433 scopus 로고    scopus 로고
    • Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
    • Dresser GK, Bailey DG, Leake BF, et al. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin Pharmacol Ther 2002;71:11-20.
    • (2002) Clin Pharmacol Ther , vol.71 , pp. 11-20
    • Dresser, G.K.1    Bailey, D.G.2    Leake, B.F.3
  • 42
    • 15344340313 scopus 로고    scopus 로고
    • Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B
    • Satoh H, Yamashita F, Tsujimoto M, et al. Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2005;33:518-23.
    • (2005) Drug Metab Dispos , vol.33 , pp. 518-523
    • Satoh, H.1    Yamashita, F.2    Tsujimoto, M.3
  • 43
    • 33947420519 scopus 로고    scopus 로고
    • Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
    • Bailey DG, Dresser GK, Leake BF, Kim RB. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin Pharmacol Ther 2007;81:495-502.
    • (2007) Clin Pharmacol Ther , vol.81 , pp. 495-502
    • Bailey, D.G.1    Dresser, G.K.2    Leake, B.F.3    Kim, R.B.4
  • 44
    • 0035145127 scopus 로고    scopus 로고
    • Seville orange juice-felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins
    • Malhotra S, Bailey DG, Paine MF, Watkins PB. Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther 2001;69:14-23.
    • (2001) Clin Pharmacol Ther , vol.69 , pp. 14-23
    • Malhotra, S.1    Bailey, D.G.2    Paine, M.F.3    Watkins, P.B.4
  • 45
    • 1642352670 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of cyclosporine: 20 years of progress
    • Kahan BD. Therapeutic drug monitoring of cyclosporine: 20 years of progress. Transplant Proc 2004;36(suppl):378S-91S.
    • (2004) Transplant Proc , vol.36 , Issue.SUPPL.
    • Kahan, B.D.1
  • 46
    • 28844459455 scopus 로고    scopus 로고
    • Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5
    • Mouly SJ, Matheny C, Paine MF, et al. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Clin Pharmacol Ther 2005;78:605-18.
    • (2005) Clin Pharmacol Ther , vol.78 , pp. 605-618
    • Mouly, S.J.1    Matheny, C.2    Paine, M.F.3


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