-
2
-
-
0242469224
-
The effects of fruit juices on drug disposition: A new model for drug interactions
-
Dresser GK, Bailey DG. The effects of fruit juices on drug disposition: a new model for drug interactions. Eur J Clin Invest 2003;33:10-6.
-
(2003)
Eur J Clin Invest
, vol.33
, pp. 10-16
-
-
Dresser, G.K.1
Bailey, D.G.2
-
3
-
-
23644436684
-
Undesirable effects of citrus juice on the pharmacokinetics of drugs: Focus on recent studies
-
Saito M, Hirata-Koizumi M, Matsumoto M, Urano T, Hasegawa R. Undesirable effects of citrus juice on the pharmacokinetics of drugs: focus on recent studies. Drug Saf 2005;28:677-94.
-
(2005)
Drug Saf
, vol.28
, pp. 677-694
-
-
Saito, M.1
Hirata-Koizumi, M.2
Matsumoto, M.3
Urano, T.4
Hasegawa, R.5
-
4
-
-
34249875093
-
Clinical relevance of the small intestine as an organ of drug elimination: Drug-fruit juice interactions. Expert Opin Drug Metab
-
Paine MF, Oberlies NH. Clinical relevance of the small intestine as an organ of drug elimination: drug-fruit juice interactions. Expert Opin Drug Metab Toxicol 2007;3:67-80.
-
(2007)
Toxicol
, vol.3
, pp. 67-80
-
-
Paine, M.F.1
Oberlies, N.H.2
-
5
-
-
0026464616
-
Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes
-
Kolars JC, Schmiedlin-Ren P, Schuetz JD, Fang C, Watkins PB. Identification of rifampin-inducible P450IIIA4 (CYP3A4) in human small bowel enterocytes. J Clin Invest 1992;90:1871-8.
-
(1992)
J Clin Invest
, vol.90
, pp. 1871-1878
-
-
Kolars, J.C.1
Schmiedlin-Ren, P.2
Schuetz, J.D.3
Fang, C.4
Watkins, P.B.5
-
6
-
-
0031445547
-
Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism
-
Paine MF, Khalighi M, Fisher JM, et al. Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. J Pharmacol Exp Ther 1997;283:1552-62.
-
(1997)
J Pharmacol Exp Ther
, vol.283
, pp. 1552-1562
-
-
Paine, M.F.1
Khalighi, M.2
Fisher, J.M.3
-
7
-
-
0030982634
-
Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression
-
Lown KS, Bailey DG, Fontana RJ, et al. Grapefruit juice increases felodipine oral availability in humans by decreasing intestinal CYP3A protein expression. J Clin Invest 1997;99:2545-53.
-
(1997)
J Clin Invest
, vol.99
, pp. 2545-2553
-
-
Lown, K.S.1
Bailey, D.G.2
Fontana, R.J.3
-
8
-
-
0030868487
-
Specific CYP3A4 inhibitors in grapefruit juice: Furocoumarin dimers as components of drug interaction
-
Fukuda K, Ohta T, Oshima Y, Ohashi N, Yoshikawa M, Yamazoe Y. Specific CYP3A4 inhibitors in grapefruit juice: furocoumarin dimers as components of drug interaction. Pharmacogenetics 1997;7:391-6.
-
(1997)
Pharmacogenetics
, vol.7
, pp. 391-396
-
-
Fukuda, K.1
Ohta, T.2
Oshima, Y.3
Ohashi, N.4
Yoshikawa, M.5
Yamazoe, Y.6
-
9
-
-
0030696487
-
Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins
-
Schmiedlin-Ren P, Edwards DJ, Fitzsimmons ME, et al. Mechanisms of enhanced oral availability of CYP3A4 substrates by grapefruit constituents. Decreased enterocyte CYP3A4 concentration and mechanism-based inactivation by furanocoumarins. Drug Metab Dispos 1997;25:1228-33.
-
(1997)
Drug Metab Dispos
, vol.25
, pp. 1228-1233
-
-
Schmiedlin-Ren, P.1
Edwards, D.J.2
Fitzsimmons, M.E.3
-
10
-
-
0031947562
-
Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice
-
He K, Iyer KR, Hayes RN, Sinz MW, Woolf TF, Hollenberg PF. Inactivation of cytochrome P450 3A4 by bergamottin, a component of grapefruit juice. Chem Res Toxicol 1998;11:252-9.
-
(1998)
Chem Res Toxicol
, vol.11
, pp. 252-259
-
-
He, K.1
Iyer, K.R.2
Hayes, R.N.3
Sinz, M.W.4
Woolf, T.F.5
Hollenberg, P.F.6
-
11
-
-
0342868292
-
Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity
-
Guo LQ, Fukuda K, Ohta T, Yamazoe Y. Role of furanocoumarin derivatives on grapefruit juice-mediated inhibition of human CYP3A activity. Drug Metab Dispos 2000;28:766-71.
-
(2000)
Drug Metab Dispos
, vol.28
, pp. 766-771
-
-
Guo, L.Q.1
Fukuda, K.2
Ohta, T.3
Yamazoe, Y.4
-
12
-
-
0034660149
-
Inhibition selectivity of grapefruit juice components on human cytochromes P450
-
Tassaneeyakul W, Guo LQ, Fukuda K, Ohta T, Yamazoe Y. Inhibition selectivity of grapefruit juice components on human cytochromes P450. Arch Biochem Biophys 2000;378:356-63.
-
(2000)
Arch Biochem Biophys
, vol.378
, pp. 356-363
-
-
Tassaneeyakul, W.1
Guo, L.Q.2
Fukuda, K.3
Ohta, T.4
Yamazoe, Y.5
-
13
-
-
4644267926
-
Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties
-
Paine MF, Criss AB, Watkins PB. Two major grapefruit juice components differ in intestinal CYP3A4 inhibition kinetic and binding properties. Drug Metab Dispos 2004;32:1146-53.
-
(2004)
Drug Metab Dispos
, vol.32
, pp. 1146-1153
-
-
Paine, M.F.1
Criss, A.B.2
Watkins, P.B.3
-
14
-
-
0034948448
-
Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats
-
Mohri K, Uesawa Y. Effects of furanocoumarin derivatives in grapefruit juice on nifedipine pharmacokinetics in rats. Pharm Res 2001;18:177-82.
-
(2001)
Pharm Res
, vol.18
, pp. 177-182
-
-
Mohri, K.1
Uesawa, Y.2
-
15
-
-
0036146639
-
The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs
-
Sahi J, Reyner EL, Bauman JN, Gueneva-Boucheva K, Burleigh JE, Thomas VH. The effect of bergamottin on diazepam plasma levels and P450 enzymes in beagle dogs. Drug Metab Dispos 2002;30:135-40.
-
(2002)
Drug Metab Dispos
, vol.30
, pp. 135-140
-
-
Sahi, J.1
Reyner, E.L.2
Bauman, J.N.3
Gueneva-Boucheva, K.4
Burleigh, J.E.5
Thomas, V.H.6
-
16
-
-
33745159659
-
A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction
-
Paine MF, Widmer WW, Hart HL, et al. A furanocoumarin-free grapefruit juice establishes furanocoumarins as the mediators of the grapefruit juice-felodipine interaction. Am J Clin Nutr 2006;83:1097-105.
-
(2006)
Am J Clin Nutr
, vol.83
, pp. 1097-1105
-
-
Paine, M.F.1
Widmer, W.W.2
Hart, H.L.3
-
17
-
-
0023447098
-
Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues
-
Thiebaut F, Tsuruo T, Hamada H, Gottesman MM, Pastan I, Willingham MC. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues. Proc Natl Acad Sci U S A 1987;84:7735-8.
-
(1987)
Proc Natl Acad Sci U S A
, vol.84
, pp. 7735-7738
-
-
Thiebaut, F.1
Tsuruo, T.2
Hamada, H.3
Gottesman, M.M.4
Pastan, I.5
Willingham, M.C.6
-
19
-
-
0028963036
-
Effect of grapefruit juice on blood cyclosporin concentration
-
Yee GC, Stanley DL, Pessa LJ, et al. Effect of grapefruit juice on blood cyclosporin concentration. Lancet 1995;345:955-6.
-
(1995)
Lancet
, vol.345
, pp. 955-956
-
-
Yee, G.C.1
Stanley, D.L.2
Pessa, L.J.3
-
20
-
-
0029055363
-
Disposition of intravenous and oral cyclosporine after administration with grapefruit juice
-
Ducharme MP, Warbasse LH, Edwards DJ. Disposition of intravenous and oral cyclosporine after administration with grapefruit juice. Clin Pharmacol Ther 1995;57:485-91.
-
(1995)
Clin Pharmacol Ther
, vol.57
, pp. 485-491
-
-
Ducharme, M.P.1
Warbasse, L.H.2
Edwards, D.J.3
-
21
-
-
0029890499
-
Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients
-
Min DI, Ku YM, Perry PJ, et al. Effect of grapefruit juice on cyclosporine pharmacokinetics in renal transplant patients. Transplantation 1996;62:123-5.
-
(1996)
Transplantation
, vol.62
, pp. 123-125
-
-
Min, D.I.1
Ku, Y.M.2
Perry, P.J.3
-
22
-
-
0031784578
-
Effect of grapefruit juice on the pharmacokinetics of microemulsion cyclosporine and its metabolite in healthy volunteers: Does the formulation difference matter?
-
Ku YM, Min DI, Flanigan M. Effect of grapefruit juice on the pharmacokinetics of microemulsion cyclosporine and its metabolite in healthy volunteers: does the formulation difference matter? J Clin Pharmacol 1998;38:959-65.
-
(1998)
J Clin Pharmacol
, vol.38
, pp. 959-965
-
-
Ku, Y.M.1
Min, D.I.2
Flanigan, M.3
-
23
-
-
0036790551
-
Intake of grapefruit juice alters the metabolic pattern of cyclosporin A in renal transplant recipients
-
Hermann M, Asberg A, Reubsaet JL, Sather S, Berg KJ, Christensen H. Intake of grapefruit juice alters the metabolic pattern of cyclosporin A in renal transplant recipients. Int J Clin Pharmacol Ther 2002;40:451-6.
-
(2002)
Int J Clin Pharmacol Ther
, vol.40
, pp. 451-456
-
-
Hermann, M.1
Asberg, A.2
Reubsaet, J.L.3
Sather, S.4
Berg, K.J.5
Christensen, H.6
-
24
-
-
0032763895
-
Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities
-
Dantzig AH, Shepard RL, Law KL, et al. Selectivity of the multidrug resistance modulator, LY335979, for P-glycoprotein and effect on cytochrome P-450 activities J Pharmacol Exp Ther 1999;290:854-62.
-
(1999)
J Pharmacol Exp Ther
, vol.290
, pp. 854-862
-
-
Dantzig, A.H.1
Shepard, R.L.2
Law, K.L.3
-
25
-
-
1342323340
-
Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir
-
Mouly SJ, Paine MF, Watkins PB. Contributions of CYP3A4, P-glycoprotein, and serum protein binding to the intestinal first-pass extraction of saquinavir. J Pharmacol Exp Ther 2004;308:941-8.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 941-948
-
-
Mouly, S.J.1
Paine, M.F.2
Watkins, P.B.3
-
27
-
-
14344258321
-
Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition
-
Paine MF, Criss AB, Watkins PB. Two major grapefruit juice components differ in time to onset of intestinal CYP3A4 inhibition. J Pharmacol Exp Ther 2005;312:1151-60.
-
(2005)
J Pharmacol Exp Ther
, vol.312
, pp. 1151-1160
-
-
Paine, M.F.1
Criss, A.B.2
Watkins, P.B.3
-
28
-
-
0038665209
-
Use of a simple solvent optimization program to improve separation of limonin in citrus juices
-
Shaw PE. Use of a simple solvent optimization program to improve separation of limonin in citrus juices. J Chromatogr Sci 1986;24:364-6.
-
(1986)
J Chromatogr Sci
, vol.24
, pp. 364-366
-
-
Shaw, P.E.1
-
29
-
-
0040485348
-
Analysis of limonin and flavonoids in citrus juices and byproduct extracts by direct injection and in-line samples clean-up
-
Berhow MA, Hasegawa S, Manners GD, eds, Washington, DC: American Chemical Society
-
Widmer WW, Haun C. Analysis of limonin and flavonoids in citrus juices and byproduct extracts by direct injection and in-line samples clean-up. In: Berhow MA, Hasegawa S, Manners GD, eds. Citrus limonoids, functional chemicals in agriculture and food. Washington, DC: American Chemical Society, 2000:60-72.
-
(2000)
Citrus limonoids, functional chemicals in agriculture and food
, pp. 60-72
-
-
Widmer, W.W.1
Haun, C.2
-
30
-
-
23744447225
-
One tangerine/grapefruit hybrid (tangelo) contains trace amounts of furanocoumarins at a level too low to be associated with grapefruit/drug interactions
-
Widmer W. One tangerine/grapefruit hybrid (tangelo) contains trace amounts of furanocoumarins at a level too low to be associated with grapefruit/drug interactions. J Food Sci 2005;70:C419-22.
-
(2005)
J Food Sci
, vol.70
-
-
Widmer, W.1
-
32
-
-
0024085610
-
C-18 solid-phase isolation and high-performance liquid-chromatography ultraviolet diode-array determination of fully methoxylated flavones in citrus juices
-
Sendra JM, Navarro JL, Izquierdo L. C-18 solid-phase isolation and high-performance liquid-chromatography ultraviolet diode-array determination of fully methoxylated flavones in citrus juices. J Chromatogr Sci 1988;26:443-8.
-
(1988)
J Chromatogr Sci
, vol.26
, pp. 443-448
-
-
Sendra, J.M.1
Navarro, J.L.2
Izquierdo, L.3
-
33
-
-
0033913305
-
Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4
-
Ohnishi A, Matsuo H, Yamada S, et al. Effect of furanocoumarin derivatives in grapefruit juice on the uptake of vinblastine by Caco-2 cells and on the activity of cytochrome P450 3A4. Br J Pharmacol 2000;130:1369-77.
-
(2000)
Br J Pharmacol
, vol.130
, pp. 1369-1377
-
-
Ohnishi, A.1
Matsuo, H.2
Yamada, S.3
-
34
-
-
0034029597
-
Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4
-
Takanaga H, Ohnishi A, Yamada S, et al. Polymethoxylated flavones in orange juice are inhibitors of P-glycoprotein but not cytochrome P450 3A4. J Pharmacol Exp Ther 2000;293:230-6.
-
(2000)
J Pharmacol Exp Ther
, vol.293
, pp. 230-236
-
-
Takanaga, H.1
Ohnishi, A.2
Yamada, S.3
-
35
-
-
34247257725
-
Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells
-
Mertens-Talcott SU, De Castro WV, Manthey JA, Derendorf H, Butterweck V. Polymethoxylated flavones and other phenolic derivates from citrus in their inhibitory effects on P-glycoprotein-mediated transport of talinolol in Caco-2 cells. J Agric Food Chem 2007;55:2563-8.
-
(2007)
J Agric Food Chem
, vol.55
, pp. 2563-2568
-
-
Mertens-Talcott, S.U.1
De Castro, W.V.2
Manthey, J.A.3
Derendorf, H.4
Butterweck, V.5
-
36
-
-
0742289647
-
Food-drug interaction: Grapefruit juice augments drug bioavailability - mechanism, extent and relevance
-
Dahan A, Altman H. Food-drug interaction: grapefruit juice augments drug bioavailability - mechanism, extent and relevance. Eur J Clin Nutr 2004;58:1-9.
-
(2004)
Eur J Clin Nutr
, vol.58
, pp. 1-9
-
-
Dahan, A.1
Altman, H.2
-
37
-
-
0035145184
-
Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients
-
Bistrup C, Nielsen FT, Jeppesen UE, Dieperink H. Effect of grapefruit juice on Sandimmun Neoral absorption among stable renal allograft recipients. Nephrol Dial Transplant 2001;16:373-7.
-
(2001)
Nephrol Dial Transplant
, vol.16
, pp. 373-377
-
-
Bistrup, C.1
Nielsen, F.T.2
Jeppesen, U.E.3
Dieperink, H.4
-
38
-
-
10844279077
-
Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux
-
Honda Y, Ushigome F, Koyabu N, et al. Effects of grapefruit juice and orange juice components on P-glycoprotein- and MRP2-mediated drug efflux. Br J Pharmacol 2004;143:856-64.
-
(2004)
Br J Pharmacol
, vol.143
, pp. 856-864
-
-
Honda, Y.1
Ushigome, F.2
Koyabu, N.3
-
39
-
-
35348973560
-
Grapefruit juice-drug interactions: Grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells
-
de Castro WV, Mertens-Talcott S, Derendorf H, Butterweck V. Grapefruit juice-drug interactions: grapefruit juice and its components inhibit P-glycoprotein (ABCB1) mediated transport of talinolol in Caco-2 cells. J Pharm Sci 2007;96:2808-17.
-
(2007)
J Pharm Sci
, vol.96
, pp. 2808-2817
-
-
de Castro, W.V.1
Mertens-Talcott, S.2
Derendorf, H.3
Butterweck, V.4
-
40
-
-
1442321728
-
6′,7′- Dihydroxybergamottin in grapefruit juice and Seville orange juice: Effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein
-
Edwards DJ, Fitzsimmons ME, Schuetz EG, et al. 6′,7′- Dihydroxybergamottin in grapefruit juice and Seville orange juice: effects on cyclosporine disposition, enterocyte CYP3A4, and P-glycoprotein. Clin Pharmacol Ther 1999;65:237-44.
-
(1999)
Clin Pharmacol Ther
, vol.65
, pp. 237-244
-
-
Edwards, D.J.1
Fitzsimmons, M.E.2
Schuetz, E.G.3
-
41
-
-
0036159433
-
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
-
Dresser GK, Bailey DG, Leake BF, et al. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin Pharmacol Ther 2002;71:11-20.
-
(2002)
Clin Pharmacol Ther
, vol.71
, pp. 11-20
-
-
Dresser, G.K.1
Bailey, D.G.2
Leake, B.F.3
-
42
-
-
15344340313
-
Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B
-
Satoh H, Yamashita F, Tsujimoto M, et al. Citrus juices inhibit the function of human organic anion-transporting polypeptide OATP-B. Drug Metab Dispos 2005;33:518-23.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 518-523
-
-
Satoh, H.1
Yamashita, F.2
Tsujimoto, M.3
-
43
-
-
33947420519
-
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice
-
Bailey DG, Dresser GK, Leake BF, Kim RB. Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice. Clin Pharmacol Ther 2007;81:495-502.
-
(2007)
Clin Pharmacol Ther
, vol.81
, pp. 495-502
-
-
Bailey, D.G.1
Dresser, G.K.2
Leake, B.F.3
Kim, R.B.4
-
44
-
-
0035145127
-
Seville orange juice-felodipine interaction: Comparison with dilute grapefruit juice and involvement of furocoumarins
-
Malhotra S, Bailey DG, Paine MF, Watkins PB. Seville orange juice-felodipine interaction: comparison with dilute grapefruit juice and involvement of furocoumarins. Clin Pharmacol Ther 2001;69:14-23.
-
(2001)
Clin Pharmacol Ther
, vol.69
, pp. 14-23
-
-
Malhotra, S.1
Bailey, D.G.2
Paine, M.F.3
Watkins, P.B.4
-
45
-
-
1642352670
-
Therapeutic drug monitoring of cyclosporine: 20 years of progress
-
Kahan BD. Therapeutic drug monitoring of cyclosporine: 20 years of progress. Transplant Proc 2004;36(suppl):378S-91S.
-
(2004)
Transplant Proc
, vol.36
, Issue.SUPPL.
-
-
Kahan, B.D.1
-
46
-
-
28844459455
-
Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5
-
Mouly SJ, Matheny C, Paine MF, et al. Variation in oral clearance of saquinavir is predicted by CYP3A5*1 genotype but not by enterocyte content of cytochrome P450 3A5. Clin Pharmacol Ther 2005;78:605-18.
-
(2005)
Clin Pharmacol Ther
, vol.78
, pp. 605-618
-
-
Mouly, S.J.1
Matheny, C.2
Paine, M.F.3
-
47
-
-
0031908050
-
Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man
-
Kupferschmidt HH, Fattinger KE, Ha HR, Follath F, Krahenbuhl S. Grapefruit juice enhances the bioavailability of the HIV protease inhibitor saquinavir in man. Br J Clin Pharmacol 1998;45:355-9.
-
(1998)
Br J Clin Pharmacol
, vol.45
, pp. 355-359
-
-
Kupferschmidt, H.H.1
Fattinger, K.E.2
Ha, H.R.3
Follath, F.4
Krahenbuhl, S.5
|