Grapefruit juice alters terfenadine pharmacokinetics, resulting in prolongation of repolarization on the electrocardiogram

Clinical Pharmacology and Therapeutics

Volumn 59, Issue 4, 1996, Pages 383-388

  Benton, Robert E ^b   Honig, Peter K ^b   Zamani, Kaveh ^b   Cantilena, Louis R ^b   Woosley, Raymond L ^a  

^a GEORGETOWN UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

DRUG METABOLITE; TERFENADINE;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; ELECTROCARDIOGRAM; FEMALE; FOOD DRUG INTERACTION; FRUIT JUICE; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; ORAL DRUG ADMINISTRATION; PHARMACODYNAMICS; PRIORITY JOURNAL; QT INTERVAL; RANDOMIZED CONTROLLED TRIAL; REPOLARIZATION;

ADULT; BEVERAGES; BIOLOGICAL AVAILABILITY; CITRUS; ELECTROCARDIOGRAPHY; FEMALE; HEART CONDUCTION SYSTEM; HISTAMINE H1 ANTAGONISTS; HUMANS; MALE; PROSPECTIVE STUDIES; TERFENADINE; TIME FACTORS;

EID: 0030012246     PISSN: 00099236     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-9236(96)90105-8     Document Type: Article

References (20)

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