메뉴 건너뛰기




Volumn 27, Issue 21, 2007, Pages 7683-7692

Essential role of endothelial Smad4 in vascular remodeling and integrity

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOPOIETIN; CONNEXIN 43; CRE RECOMBINASE; SMAD4 PROTEIN;

EID: 35648947847     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00577-07     Document Type: Article
Times cited : (100)

References (50)
  • 1
    • 17144362541 scopus 로고    scopus 로고
    • Preferential activity of Tie2 promoter in arteriolar endothelium
    • Anghelina, M., L. Moldovan, and N. I. Moldovan. 2005. Preferential activity of Tie2 promoter in arteriolar endothelium. J. Cell Mol. Med. 9:113-121.
    • (2005) J. Cell Mol. Med , vol.9 , pp. 113-121
    • Anghelina, M.1    Moldovan, L.2    Moldovan, N.I.3
  • 2
    • 0001505189 scopus 로고
    • An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes
    • Antonelli-Orlidge, A., K. B. Saunders, S. R. Smith, and P. A. D'Amore. 1989. An activated form of transforming growth factor beta is produced by cocultures of endothelial cells and pericytes. Proc. Natl. Acad. Sci. USA 86:4544-4548.
    • (1989) Proc. Natl. Acad. Sci. USA , vol.86 , pp. 4544-4548
    • Antonelli-Orlidge, A.1    Saunders, K.B.2    Smith, S.R.3    D'Amore, P.A.4
  • 3
    • 4444320851 scopus 로고    scopus 로고
    • Heart valve development: Endothelial cell signaling and differentiation
    • Armstrong, E. J., and J. Bischoff. 2004. Heart valve development: endothelial cell signaling and differentiation. Circ. Res. 95:459-470.
    • (2004) Circ. Res , vol.95 , pp. 459-470
    • Armstrong, E.J.1    Bischoff, J.2
  • 4
    • 25444463573 scopus 로고    scopus 로고
    • Endothelial/pericyte interactions
    • Armulik, A., A. Abramsson, and C. Betsholtz. 2005. Endothelial/pericyte interactions. Circ. Res. 97:512-523.
    • (2005) Circ. Res , vol.97 , pp. 512-523
    • Armulik, A.1    Abramsson, A.2    Betsholtz, C.3
  • 5
    • 12344255297 scopus 로고    scopus 로고
    • Defective paracrine signaling by TGFβ in yolk sac vasculature of endoglin mutant mice: A paradigm for hereditary haemorrhagic telangiectasia
    • Carvalho, R. L., L. Jonker, M. J. Goumans, J. Larsson, P. Bouwman, S. Karlsson, P. T. Dijke, H. M. Arthur, and C. L. Mummery. 2004. Defective paracrine signaling by TGFβ in yolk sac vasculature of endoglin mutant mice: a paradigm for hereditary haemorrhagic telangiectasia. Development 131:6237-6247.
    • (2004) Development , vol.131 , pp. 6237-6247
    • Carvalho, R.L.1    Jonker, L.2    Goumans, M.J.3    Larsson, J.4    Bouwman, P.5    Karlsson, S.6    Dijke, P.T.7    Arthur, H.M.8    Mummery, C.L.9
  • 6
    • 0032101178 scopus 로고    scopus 로고
    • Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene
    • Dennler, S., S. Itoh, D. Vivien, P. ten Dijke, S. Huet, and J. M. Gauthier. 1998. Direct binding of Smad3 and Smad4 to critical TGFβ-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene. EMBO J. 17:3091-3100.
    • (1998) EMBO J , vol.17 , pp. 3091-3100
    • Dennler, S.1    Itoh, S.2    Vivien, D.3    ten Dijke, P.4    Huet, S.5    Gauthier, J.M.6
  • 7
    • 0029074681 scopus 로고
    • Defective hematopoiesis and vasculogenesis in transforming growth factor-β1 knockout mice
    • Dickson, M. C., J. S. Martin, F. M. Cousins, A. B. Kulkarni, S. Karlsson, and R. J. Akhurst. 1995. Defective hematopoiesis and vasculogenesis in transforming growth factor-β1 knockout mice. Development 121:1845-1854.
    • (1995) Development , vol.121 , pp. 1845-1854
    • Dickson, M.C.1    Martin, J.S.2    Cousins, F.M.3    Kulkarni, A.B.4    Karlsson, S.5    Akhurst, R.J.6
  • 8
    • 33344477298 scopus 로고    scopus 로고
    • Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling
    • Eklund, L., and B. R. Olsen. 2006. Tie receptors and their angiopoietin ligands are context-dependent regulators of vascular remodeling. Exp. Cell Res. 312:630-641.
    • (2006) Exp. Cell Res , vol.312 , pp. 630-641
    • Eklund, L.1    Olsen, B.R.2
  • 9
    • 30144432172 scopus 로고    scopus 로고
    • Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors
    • Ema, M., S. Takahashi, and J. Rossant. 2006. Deletion of the selection cassette, but not cis-acting elements, in targeted Flk1-lacZ allele reveals Flk1 expression in multipotent mesodermal progenitors. Blood 107:111-117.
    • (2006) Blood , vol.107 , pp. 111-117
    • Ema, M.1    Takahashi, S.2    Rossant, J.3
  • 12
    • 0037007226 scopus 로고    scopus 로고
    • Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
    • Goumans, M. J., G. Valdimarsdottir, S. Itoh, A. Rosendahl, P. Sideras, and P. ten Dijke. 2002. Balancing the activation state of the endothelium via two distinct TGF-β type I receptors. EMBO J. 21:1743-1753.
    • (2002) EMBO J , vol.21 , pp. 1743-1753
    • Goumans, M.J.1    Valdimarsdottir, G.2    Itoh, S.3    Rosendahl, A.4    Sideras, P.5    ten Dijke, P.6
  • 13
    • 0034695506 scopus 로고    scopus 로고
    • OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
    • Hata, A., J. Seoane, G. Lagna, E. Montalvo, A. Hemmati-Brivanlou, and J. Massague. 2000. OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100:229-240.
    • (2000) Cell , vol.100 , pp. 229-240
    • Hata, A.1    Seoane, J.2    Lagna, G.3    Montalvo, E.4    Hemmati-Brivanlou, A.5    Massague, J.6
  • 14
    • 0031811772 scopus 로고    scopus 로고
    • Isolation and characterization of endothelial progenitor cells from mouse embryos
    • Hatzopoulos, A. K., J. Folkman, E. Vasile, G. K. Eiselen, and R. D. Rosenberg. 1998. Isolation and characterization of endothelial progenitor cells from mouse embryos. Development 125:1457-1468.
    • (1998) Development , vol.125 , pp. 1457-1468
    • Hatzopoulos, A.K.1    Folkman, J.2    Vasile, E.3    Eiselen, G.K.4    Rosenberg, R.D.5
  • 15
    • 0042917501 scopus 로고    scopus 로고
    • Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation
    • Hirschi, K. K., J. M. Burt, K. D. Hirschi, and C. Dai. 2003. Gap junction communication mediates transforming growth factor-beta activation and endothelial-induced mural cell differentiation. Circ. Res. 93:429-437.
    • (2003) Circ. Res , vol.93 , pp. 429-437
    • Hirschi, K.K.1    Burt, J.M.2    Hirschi, K.D.3    Dai, C.4
  • 16
    • 0032482202 scopus 로고    scopus 로고
    • PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate
    • Hirschi, K. K., S. A. Rohovsky, and P. A. D'Amore. 1998. PDGF, TGF-beta, and heterotypic cell-cell interactions mediate endothelial cell-induced recruitment of 10T1/2 cells and their differentiation to a smooth muscle fate. J. Cell Biol. 141:805-814.
    • (1998) J. Cell Biol , vol.141 , pp. 805-814
    • Hirschi, K.K.1    Rohovsky, S.A.2    D'Amore, P.A.3
  • 17
    • 0033104505 scopus 로고    scopus 로고
    • TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway
    • Hocevar, B. A., T. L. Brown, and P. H. Howe. 1999. TGF-beta induces fibronectin synthesis through a c-Jun N-terminal kinase-dependent, Smad4-independent pathway. EMBO J. 18:1345-1356.
    • (1999) EMBO J , vol.18 , pp. 1345-1356
    • Hocevar, B.A.1    Brown, T.L.2    Howe, P.H.3
  • 20
    • 0035168133 scopus 로고    scopus 로고
    • Inhibition of endothelial wound repair by dominant negative connexin inhibitors
    • Kwak, B. R., M. S. Pepper, D. B. Gros, and P. Meda. 2001. Inhibition of endothelial wound repair by dominant negative connexin inhibitors. Mol. Biol. Cell 12:831-845.
    • (2001) Mol. Biol. Cell , vol.12 , pp. 831-845
    • Kwak, B.R.1    Pepper, M.S.2    Gros, D.B.3    Meda, P.4
  • 21
    • 1842855648 scopus 로고    scopus 로고
    • TGF-beta1 induces an accumulation of connexin43 in a lysosomal compartment in endothelial cells
    • Larson, D. M., T. G. Christensen, G. D. Sagar, and E. C. Beyer. 2001. TGF-beta1 induces an accumulation of connexin43 in a lysosomal compartment in endothelial cells. Endothelium 8:255-260.
    • (2001) Endothelium , vol.8 , pp. 255-260
    • Larson, D.M.1    Christensen, T.G.2    Sagar, G.D.3    Beyer, E.C.4
  • 26
    • 24944569595 scopus 로고    scopus 로고
    • Endothelial cell-specific expression of Cre recombinase in transgenic mice
    • Li, W. L., X. Cheng, X. H. Tan, J. S. Zhang, Y. S. Sun, L. Chen, and X. Yang. 2005. Endothelial cell-specific expression of Cre recombinase in transgenic mice. Yi Chuan Xue Bao 32:909-915.
    • (2005) Yi Chuan Xue Bao , vol.32 , pp. 909-915
    • Li, W.L.1    Cheng, X.2    Tan, X.H.3    Zhang, J.S.4    Sun, Y.S.5    Chen, L.6    Yang, X.7
  • 28
    • 0032547764 scopus 로고    scopus 로고
    • Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia
    • Mandriota, S. J., and M. S. Pepper. 1998. Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia. Circ. Res. 83:852-859.
    • (1998) Circ. Res , vol.83 , pp. 852-859
    • Mandriota, S.J.1    Pepper, M.S.2
  • 32
    • 0030579203 scopus 로고    scopus 로고
    • TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis
    • Oshima, M., H. Oshima, and M. M. Taketo. 1996. TGF-beta receptor type II deficiency results in defects of yolk sac hematopoiesis and vasculogenesis. Dev. Biol. 179:297-302.
    • (1996) Dev. Biol , vol.179 , pp. 297-302
    • Oshima, M.1    Oshima, H.2    Taketo, M.M.3
  • 33
    • 0036888627 scopus 로고    scopus 로고
    • Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells
    • Ota, T., M. Fujii, T. Sugizaki, M. Ishii, K. Miyazawa, H. Aburatani, and K. Miyazono. 2002. Targets of transcriptional regulation by two distinct type I receptors for transforming growth factor-beta in human umbilical vein endothelial cells. J. Cell Physiol. 193:299-318.
    • (2002) J. Cell Physiol , vol.193 , pp. 299-318
    • Ota, T.1    Fujii, M.2    Sugizaki, T.3    Ishii, M.4    Miyazawa, K.5    Aburatani, H.6    Miyazono, K.7
  • 34
    • 33749379585 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation
    • Park, C., K. Lavine, Y. Mishina, C. X. Deng, D. M. Ornitz, and K. Choi. 2006. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development 133:3473-3484.
    • (2006) Development , vol.133 , pp. 3473-3484
    • Park, C.1    Lavine, K.2    Mishina, Y.3    Deng, C.X.4    Ornitz, D.M.5    Choi, K.6
  • 35
    • 14944377120 scopus 로고    scopus 로고
    • The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism
    • Scharpfenecker, M., U. Fiedler, Y. Reiss, and H. G. Augustin. 2005. The Tie-2 ligand angiopoietin-2 destabilizes quiescent endothelium through an internal autocrine loop mechanism. J. Cell Sci. 118:771-780.
    • (2005) J. Cell Sci , vol.118 , pp. 771-780
    • Scharpfenecker, M.1    Fiedler, U.2    Reiss, Y.3    Augustin, H.G.4
  • 38
    • 0141752813 scopus 로고    scopus 로고
    • Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling
    • Seki, T., J. Yun, and S. P. Oh. 2003. Arterial endothelium-specific activin receptor-like kinase 1 expression suggests its role in arterialization and vascular remodeling. Circ. Res. 93:682-689.
    • (2003) Circ. Res , vol.93 , pp. 682-689
    • Seki, T.1    Yun, J.2    Oh, S.P.3
  • 39
    • 0032923739 scopus 로고    scopus 로고
    • Generalized lacZ expression with the ROSA26 Cre reporter strain
    • Soriano, P. 1999. Generalized lacZ expression with the ROSA26 Cre reporter strain. Nat. Genet. 21:70-71.
    • (1999) Nat. Genet , vol.21 , pp. 70-71
    • Soriano, P.1
  • 40
    • 18844457634 scopus 로고    scopus 로고
    • Disruption of Smad5 gene induces mitochondria-dependent apoptosis in cardiomyocytes
    • Sun, Y., J. Zhou, X. Liao, Y. Lu, C. Deng, P. Huang, Q. Chen, and X. Yang. 2005. Disruption of Smad5 gene induces mitochondria-dependent apoptosis in cardiomyocytes. Exp. Cell Res. 306:85-93.
    • (2005) Exp. Cell Res , vol.306 , pp. 85-93
    • Sun, Y.1    Zhou, J.2    Liao, X.3    Lu, Y.4    Deng, C.5    Huang, P.6    Chen, Q.7    Yang, X.8
  • 41
    • 33644748673 scopus 로고    scopus 로고
    • pVHL function is essential for endothelial extracellular matrix deposition
    • Tang, N., F. Mack, V. H. Haase, M. C. Simon, and R. S. Johnson. 2006. pVHL function is essential for endothelial extracellular matrix deposition. Mol. Cell. Biol. 26:2519-2530.
    • (2006) Mol. Cell. Biol , vol.26 , pp. 2519-2530
    • Tang, N.1    Mack, F.2    Haase, V.H.3    Simon, M.C.4    Johnson, R.S.5
  • 42
    • 0034595653 scopus 로고    scopus 로고
    • Induction of platelet-derived growth factor B-chain expression by transforming growth factor-beta involves transactivation by Smads
    • Taylor, L. M., and L. M. Khachigian. 2000. Induction of platelet-derived growth factor B-chain expression by transforming growth factor-beta involves transactivation by Smads. J. Biol. Chem. 275:16709-16716.
    • (2000) J. Biol. Chem , vol.275 , pp. 16709-16716
    • Taylor, L.M.1    Khachigian, L.M.2
  • 43
    • 2342488852 scopus 로고    scopus 로고
    • New insights into TGF-β-Smad signaling
    • ten Dijke, P., and C. S. Hill. 2004. New insights into TGF-β-Smad signaling. Trends Biochem. Sci. 29:265-273.
    • (2004) Trends Biochem. Sci , vol.29 , pp. 265-273
    • ten Dijke, P.1    Hill, C.S.2
  • 44
    • 0037513430 scopus 로고    scopus 로고
    • Role of Smad4 on TGF-β-induced extracellular matrix stimulation in mesangial cells
    • Tsuchida, K., Y. Zhu, S. Siva, S. R. Dunn, and K. Sharma. 2003. Role of Smad4 on TGF-β-induced extracellular matrix stimulation in mesangial cells. Kidney Int. 63:2000-2009.
    • (2003) Kidney Int , vol.63 , pp. 2000-2009
    • Tsuchida, K.1    Zhu, Y.2    Siva, S.3    Dunn, S.R.4    Sharma, K.5
  • 46
    • 0037159280 scopus 로고    scopus 로고
    • Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells
    • Valdimarsdottir, G., M. J. Goumans, A. Rosendahl, M. Brugman, S. Itoh, F. Lebrin, P. Sideras, and P. ten Dijke. 2002. Stimulation of Id1 expression by bone morphogenetic protein is sufficient and necessary for bone morphogenetic protein-induced activation of endothelial cells. Circulation 106:2263-2270.
    • (2002) Circulation , vol.106 , pp. 2263-2270
    • Valdimarsdottir, G.1    Goumans, M.J.2    Rosendahl, A.3    Brugman, M.4    Itoh, S.5    Lebrin, F.6    Sideras, P.7    ten Dijke, P.8
  • 47
    • 31744451275 scopus 로고    scopus 로고
    • Distinct regulation of gene expression in human endothelial cells by TGF-β and its receptors
    • Wu, X., J. Ma, J. D. Han, N. Wang, and Y. G. Chen. 2006. Distinct regulation of gene expression in human endothelial cells by TGF-β and its receptors. Microvasc. Res. 71:12-19.
    • (2006) Microvasc. Res , vol.71 , pp. 12-19
    • Wu, X.1    Ma, J.2    Han, J.D.3    Wang, N.4    Chen, Y.G.5
  • 49
    • 0036193069 scopus 로고    scopus 로고
    • Generation of Smad4/Dpc4 conditional knockout mice
    • Yang, X., C. Li, P. L. Herrera, and C. X. Deng. 2002. Generation of Smad4/Dpc4 conditional knockout mice. Genesis 32:80-81.
    • (2002) Genesis , vol.32 , pp. 80-81
    • Yang, X.1    Li, C.2    Herrera, P.L.3    Deng, C.X.4
  • 50
    • 0032584068 scopus 로고    scopus 로고
    • The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice
    • Yang, X., C. Li, X. Xu, and C. Deng. 1998. The tumor suppressor SMAD4/DPC4 is essential for epiblast proliferation and mesoderm induction in mice. Proc. Natl. Acad. Sci. USA 95:3667-3672.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3667-3672
    • Yang, X.1    Li, C.2    Xu, X.3    Deng, C.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.