메뉴 건너뛰기




Volumn 291, Issue 5, 2006, Pages

BMP-dependent activation of caspase-9 and caspase-8 mediates apoptosis in pulmonary artery smooth muscle cells

Author keywords

Bone morphogenetic protein receptor type II; Smad; Transforming growth factor

Indexed keywords

BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN RECEPTOR; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; MUTANT PROTEIN; OSTEOGENIC PROTEIN 1; PROTEIN BCL 2;

EID: 33751074163     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00180.2006     Document Type: Article
Times cited : (60)

References (44)
  • 1
    • 20444501324 scopus 로고    scopus 로고
    • Lessons learned from cancer may help in the treatment of pulmonary hypertension
    • Adnot S. Lessons learned from cancer may help in the treatment of pulmonary hypertension. J Clin Invest 115: 1461-1463, 2005.
    • (2005) J Clin Invest , vol.115 , pp. 1461-1463
    • Adnot, S.1
  • 2
    • 0030058085 scopus 로고    scopus 로고
    • Tumor-specific expression and alternate splicing of messenger ribonucleic acid encoding activin/transforming growth factor-beta receptors in human pituitary adenomas
    • Alexander JM, Bikkal HA, Zervas NT, Laws ER Jr, Klibanski A. Tumor-specific expression and alternate splicing of messenger ribonucleic acid encoding activin/transforming growth factor-beta receptors in human pituitary adenomas. J Clin Endocrinol Metab 81: 783-790, 1996.
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 783-790
    • Alexander, J.M.1    Bikkal, H.A.2    Zervas, N.T.3    Laws Jr., E.R.4    Klibanski, A.5
  • 5
    • 3042710723 scopus 로고    scopus 로고
    • Induction of Bax and activation of caspases during β-sitosterol- mediated apoptosis in human colon cancer cells
    • Choi YH, Kong KR, Kim YA, Jung KO, Kil JH, Rhee SH, Park KY. Induction of Bax and activation of caspases during β-sitosterol-mediated apoptosis in human colon cancer cells. Int J Oncol 23: 1657-1662, 2003.
    • (2003) Int J Oncol , vol.23 , pp. 1657-1662
    • Choi, Y.H.1    Kong, K.R.2    Kim, Y.A.3    Jung, K.O.4    Kil, J.H.5    Rhee, S.H.6    Park, K.Y.7
  • 6
    • 0036716281 scopus 로고    scopus 로고
    • The Bcl2 family: Regulators of the cellular life-or-death switch
    • Cory S, Adams JM. The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647-656, 2002.
    • (2002) Nat Rev Cancer , vol.2 , pp. 647-656
    • Cory, S.1    Adams, J.M.2
  • 7
    • 0034126770 scopus 로고    scopus 로고
    • Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor
    • Cowan KN, Heilbut A, Humpl T, Lam C, Ito S, Rabinovitch M. Complete reversal of fatal pulmonary hypertension in rats by a serine elastase inhibitor. Nat Med 6: 698-702, 2000.
    • (2000) Nat Med , vol.6 , pp. 698-702
    • Cowan, K.N.1    Heilbut, A.2    Humpl, T.3    Lam, C.4    Ito, S.5    Rabinovitch, M.6
  • 8
    • 0842281645 scopus 로고    scopus 로고
    • Cell death: Critical control points
    • Danial NN, Korsmeyer SJ. Cell death: critical control points. Cell 116: 205-219, 2004.
    • (2004) Cell , vol.116 , pp. 205-219
    • Danial, N.N.1    Korsmeyer, S.J.2
  • 9
    • 0034074899 scopus 로고    scopus 로고
    • Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro
    • Dorai H, Vukicevic S, Sampath TK. Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro. J Cell Physiol 184: 37-45, 2000.
    • (2000) J Cell Physiol , vol.184 , pp. 37-45
    • Dorai, H.1    Vukicevic, S.2    Sampath, T.K.3
  • 11
    • 0027373733 scopus 로고
    • The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans larva development
    • Estevez M, Attisano L, Wrana JL, Albert PS, Massagué J, Riddle DL. The daf-4 gene encodes a bone morphogenetic protein receptor controlling C. elegans larva development. Nature 365: 644-649, 1993.
    • (1993) Nature , vol.365 , pp. 644-649
    • Estevez, M.1    Attisano, L.2    Wrana, J.L.3    Albert, P.S.4    Massagué, J.5    Riddle, D.L.6
  • 13
    • 0034695506 scopus 로고    scopus 로고
    • OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways
    • Hata A, Seoane J, Lagna G, Montalvo E, Hemmati-Brivanlou A, Massague J. OAZ uses distinct DNA- and protein-binding zinc fingers in separate BMP-Smad and Olf signaling pathways. Cell 100: 229-240, 2000.
    • (2000) Cell , vol.100 , pp. 229-240
    • Hata, A.1    Seoane, J.2    Lagna, G.3    Montalvo, E.4    Hemmati-Brivanlou, A.5    Massague, J.6
  • 14
    • 0035800764 scopus 로고    scopus 로고
    • Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway
    • Hay E, Lemonnier J, Fromigue O, Marie PJ. Bone morphogenetic protein-2 promotes osteoblast apoptosis through a Smad-independent, protein kinase C-dependent signaling pathway. J Biol Chem 276: 29028-29036, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 29028-29036
    • Hay, E.1    Lemonnier, J.2    Fromigue, O.3    Marie, P.J.4
  • 15
    • 0029737070 scopus 로고    scopus 로고
    • Bone morphogenetic proteins: Multifunctional regulators of vertebrate development
    • Hogan BLM. Bone morphogenetic proteins: multifunctional regulators of vertebrate development. Genes Dev 10: 1580-1594, 1996.
    • (1996) Genes Dev , vol.10 , pp. 1580-1594
    • Hogan, B.L.M.1
  • 16
    • 0028866028 scopus 로고
    • Truncated type II receptor for BMP-4 induces secondary axial structures in Xenopus embryos
    • Ishikawa T, Yoshioka H, Ohuchi H, Noji S, Nohno T. Truncated type II receptor for BMP-4 induces secondary axial structures in Xenopus embryos. Biochem Biophys Res Commun 216: 26-33, 1995.
    • (1995) Biochem Biophys Res Commun , vol.216 , pp. 26-33
    • Ishikawa, T.1    Yoshioka, H.2    Ohuchi, H.3    Noji, S.4    Nohno, T.5
  • 17
    • 0037837819 scopus 로고    scopus 로고
    • Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor β1 in the regulation of vascular smooth muscle cell phenotype
    • King KE, Iyemere VP, Weissberg PL, Shanahan CM. Kruppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor β1 in the regulation of vascular smooth muscle cell phenotype. J Biol Chem 278: 11661-11669, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 11661-11669
    • King, K.E.1    Iyemere, V.P.2    Weissberg, P.L.3    Shanahan, C.M.4
  • 18
    • 33646187368 scopus 로고    scopus 로고
    • OAZ regulates BMP signaling through SMAD6 activation
    • Ku M, Howard S, Ni W, Lagna G, Hata A. OAZ regulates BMP signaling through SMAD6 activation. J Biol Chem 281: 5277-5287, 2006.
    • (2006) J Biol Chem , vol.281 , pp. 5277-5287
    • Ku, M.1    Howard, S.2    Ni, W.3    Lagna, G.4    Hata, A.5
  • 19
    • 23344444858 scopus 로고    scopus 로고
    • Positive and negative regulation of the transforming growth factor β/activin target gene goosecoid by the TFII-I family of transcription factors
    • Ku MC, Sokol SY, Wu J, Tussie-Luna MI, Roy AL, Hata A. Positive and negative regulation of the transforming growth factor β/activin target gene goosecoid by the TFII-I family of transcription factors. Mol Cell Biol 25: 7144-7157, 2005.
    • (2005) Mol Cell Biol , vol.25 , pp. 7144-7157
    • Ku, M.C.1    Sokol, S.Y.2    Wu, J.3    Tussie-Luna, M.I.4    Roy, A.L.5    Hata, A.6
  • 20
    • 11244313831 scopus 로고    scopus 로고
    • Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis
    • Lee-Hoeflich ST, Causing CG, Podkowa M, Zhao X, Wrana JL, Attisano L. Activation of LIMK1 by binding to the BMP receptor, BMPRII, regulates BMP-dependent dendritogenesis. EMBO J 23: 4792-4801, 2004.
    • (2004) EMBO J , vol.23 , pp. 4792-4801
    • Lee-Hoeflich, S.T.1    Causing, C.G.2    Podkowa, M.3    Zhao, X.4    Wrana, J.L.5    Attisano, L.6
  • 24
    • 0348013127 scopus 로고    scopus 로고
    • Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension
    • Machado RD, Rudarakanchana N, Atkinson C, Flanagan JA, Harrison R, Morrell NW, Trembath RC. Functional interaction between BMPR-II and Tctex-1, a light chain of Dynein, is isoform-specific and disrupted by mutations underlying primary pulmonary hypertension. Hum Mol Genet 12: 3277-3286, 2003.
    • (2003) Hum Mol Genet , vol.12 , pp. 3277-3286
    • Machado, R.D.1    Rudarakanchana, N.2    Atkinson, C.3    Flanagan, J.A.4    Harrison, R.5    Morrell, N.W.6    Trembath, R.C.7
  • 25
    • 0032475884 scopus 로고    scopus 로고
    • Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2
    • Macias-Silva M, Hoodless PA, Tang SJ, Buchwald M, Wrana JL. Specific activation of Smad1 signaling pathways by the BMP7 type I receptor, ALK2. J Biol Chem 273: 25628-25636, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 25628-25636
    • Macias-Silva, M.1    Hoodless, P.A.2    Tang, S.J.3    Buchwald, M.4    Wrana, J.L.5
  • 26
    • 4043164852 scopus 로고    scopus 로고
    • Molecular biology of primary pulmonary hypertension
    • Mandegar M, Thistlethwaite PA, Yuan JX. Molecular biology of primary pulmonary hypertension. Cardiol Clin 22: 417-429, 2004.
    • (2004) Cardiol Clin , vol.22 , pp. 417-429
    • Mandegar, M.1    Thistlethwaite, P.A.2    Yuan, J.X.3
  • 27
  • 30
    • 28744450250 scopus 로고    scopus 로고
    • Pathobiology of pulmonary arterial hypertension
    • Naeije R, Rondelet B. Pathobiology of pulmonary arterial hypertension. Bull Mem Acad R Med Belg 159: 219-226, 2004.
    • (2004) Bull Mem Acad R Med Belg , vol.159 , pp. 219-226
    • Naeije, R.1    Rondelet, B.2
  • 32
    • 0031671673 scopus 로고    scopus 로고
    • Elastase and unexplained pulmonary hypertension
    • Rabinovitch M. Elastase and unexplained pulmonary hypertension. Chest 114: 213S-224S, 1998.
    • (1998) Chest , vol.114
    • Rabinovitch, M.1
  • 34
    • 0030934358 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of pulmonary vascular remodeling
    • Stenmark KR, Mecham RP. Cellular and molecular mechanisms of pulmonary vascular remodeling. Annu Rev Physiol 59: 89-144, 1997.
    • (1997) Annu Rev Physiol , vol.59 , pp. 89-144
    • Stenmark, K.R.1    Mecham, R.P.2
  • 35
    • 33644865928 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: Implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension
    • Teichert-Kuliszewska K, Kutryk MJ, Kuliszewski MA, Karoubi G, Courtman DW, Zucco L, Granton J, Stewart DJ. Bone morphogenetic protein receptor-2 signaling promotes pulmonary arterial endothelial cell survival: implications for loss-of-function mutations in the pathogenesis of pulmonary hypertension. Circ Res 98: 209-217, 2006.
    • (2006) Circ Res , vol.98 , pp. 209-217
    • Teichert-Kuliszewska, K.1    Kutryk, M.J.2    Kuliszewski, M.A.3    Karoubi, G.4    Courtman, D.W.5    Zucco, L.6    Granton, J.7    Stewart, D.J.8
  • 39
    • 27644572195 scopus 로고    scopus 로고
    • Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: Implication for a role in pulmonary arterial hypertension
    • Wong WK, Knowles JA, Morse JH. Bone morphogenetic protein receptor type II C-terminus interacts with c-Src: implication for a role in pulmonary arterial hypertension. Am J Respir Cell Mol Biol 33: 438-446, 2005.
    • (2005) Am J Respir Cell Mol Biol , vol.33 , pp. 438-446
    • Wong, W.K.1    Knowles, J.A.2    Morse, J.H.3
  • 41
    • 0033652983 scopus 로고    scopus 로고
    • Detection of multiple bone morphogenetic protein messenger ribonucleic acids and their signal transducer, Smad1, during mouse decidualization
    • Ying Y, Zhao GQ. Detection of multiple bone morphogenetic protein messenger ribonucleic acids and their signal transducer, Smad1, during mouse decidualization. Biol Reprod 63: 1781-1786, 2000.
    • (2000) Biol Reprod , vol.63 , pp. 1781-1786
    • Ying, Y.1    Zhao, G.Q.2
  • 42
    • 21644447416 scopus 로고    scopus 로고
    • Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells
    • Yu PB, Beppu H, Kawai N, Li E, Bloch KD. Bone morphogenetic protein (BMP) type II receptor deletion reveals BMP ligand-specific gain of signaling in pulmonary artery smooth muscle cells. J Biol Chem 280: 24443-24450, 2005.
    • (2005) J Biol Chem , vol.280 , pp. 24443-24450
    • Yu, P.B.1    Beppu, H.2    Kawai, N.3    Li, E.4    Bloch, K.D.5
  • 44
    • 0030955344 scopus 로고    scopus 로고
    • Distinct roles of type I BMP receptors in the formation and differentiation of cartilage
    • Zou H, Wieser R, Massagué J, Niswander L. Distinct roles of type I BMP receptors in the formation and differentiation of cartilage. Genes Dev 11: 2191-2203, 1997.
    • (1997) Genes Dev , vol.11 , pp. 2191-2203
    • Zou, H.1    Wieser, R.2    Massagué, J.3    Niswander, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.