Endoglin, an ancillary TGFβ receptor, is required for extraembryonic angiogenesis and plays a key role in heart development

Developmental Biology

Volumn 217, Issue 1, 2000, Pages 42-53

  Arthur, H M ^a   Ure, J ^c   Smith, A J H ^c   Renforth, G ^a   Wilson, D I ^a   Torsney, E ^a,d   Charlton, R ^d   Parums, D V ^d   Jowett, T ^a   Marchuk, D A ^e   Burn, J ^a   Diamond, A G ^b  

^a School of Biochemistry and Genetics   (United Kingdom)

^b NEWCASTLE UNIVERSITY   (United Kingdom)

^c UNIVERSITY OF EDINBURGH   (United Kingdom)

^d FREEMAN HOSPITAL   (United Kingdom)

^e DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Angioigenesis; Cardiogenesis; Endoglin; Haematopoiesis; HHT; TGF

Indexed keywords

ENDOGLIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; LEUKOCYTE ANTIGEN; PRIMER DNA; VASCULAR CELL ADHESION MOLECULE 1;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONGENITAL BLOOD VESSEL MALFORMATION; EMBRYO; EMBRYO DEVELOPMENT; HEART DEVELOPMENT; HEMATOPOIESIS; KNOCKOUT GENE; MEMBRANE BINDING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RENDU OSLER WEBER DISEASE; SIGNAL TRANSDUCTION; ANIMAL; C57BL MOUSE; GENETICS; HEART; HETEROZYGOTE; LETHAL GENE; METABOLISM; MOUSE MUTANT; NUCLEOTIDE SEQUENCE; PATHOPHYSIOLOGY; PHYSIOLOGY; PRENATAL DEVELOPMENT; STOP CODON; VASCULAR ENDOTHELIUM;

ANIMALIA; MAMMALIA;

ANIMALS; ANTIGENS, CD; BASE SEQUENCE; CODON, TERMINATOR; DNA PRIMERS; ENDOTHELIUM, VASCULAR; GENES, LETHAL; HEART; HEMATOPOIESIS; HETEROZYGOTE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEOVASCULARIZATION, PHYSIOLOGIC; RECEPTORS, CELL SURFACE; TELANGIECTASIA, HEREDITARY HEMORRHAGIC; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0033621804     PISSN: 00121606     EISSN: None     Source Type: Journal    
DOI: 10.1006/dbio.1999.9534     Document Type: Article

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