Age-dependent endothelial nitric oxide synthase uncoupling in pulmonary arteries of endoglin heterozygous mice

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 297, Issue 6, 2009, Pages

  Belik, J ^a,b   Jerkic, M ^a,b   McIntyre, B A S ^a,b   Pan, J ^a,b   Leen, J ^a   Yu, L X ^a,c   Henkelman, R M ^a,c   Toporsian, M ^d   Letarte, M ^a,b  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

Author keywords

Hereditary hemorrhagic telangiectasia; Lung; Newborn; Pulmonary vascular resistance

Indexed keywords

ACETYLCHOLINE; COPPER ZINC SUPEROXIDE DISMUTASE; ENDOGLIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; MANGANESE SUPEROXIDE DISMUTASE; N(G) NITROARGININE METHYL ESTER; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4;

ADULT ANIMAL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; LUNG PARENCHYMA; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; VASODILATATION;

AGING; ANIMALS; ANIMALS, NEWBORN; BIOMECHANICS; ENDOTHELIAL CELLS; HETEROZYGOTE; HSP90 HEAT-SHOCK PROTEINS; HYDROGEN PEROXIDE; IMMUNOPRECIPITATION; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG; MICE; NADPH OXIDASE; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ARTERY; SUPEROXIDE DISMUTASE; TOMOGRAPHY, X-RAY COMPUTED; VASODILATION;

EID: 71949131399     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00168.2009     Document Type: Article

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