Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice

Circulation Research

Volumn 98, Issue 6, 2006, Pages 818-827

  Long, Lu ^a   MacLean, Margaret R ^b   Jeffery, Trina K ^a   Morecroft, Ian ^b   Yang, Xudong ^a   Rudarakanchana, Nung ^a   Southwood, Mark ^a   James, Victoria ^c   Trembath, Richard C ^c   Morrell, Nicholas W ^a,d  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d ADDENBROOKE S HOSPITAL   (United Kingdom)

Author keywords

Bone morphogenetic protein; Pulmonary arterial hypertension; Serotonin

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; MITOGEN ACTIVATED PROTEIN KINASE 1; SEROTONIN; SEROTONIN 1 RECEPTOR; SEROTONIN 2 RECEPTOR; BMP2 PROTEIN, MOUSE; BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN RECEPTOR 2; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; SEROTONIN RECEPTOR; SEROTONIN TRANSPORTER; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BMPR2 GENE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DNA SYNTHESIS; ENVIRONMENTAL FACTOR; GENE; GENE MUTATION; GENETIC SUSCEPTIBILITY; HYPOXIA; LUNG ARTERY PRESSURE; LUNG BLOOD FLOW; LUNG HEMODYNAMICS; LUNG VASCULAR RESISTANCE; MOUSE; NONHUMAN; PENETRANCE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; ANIMAL; ANOXIA; C57BL MOUSE; CELL CULTURE; CELL PROLIFERATION; DRUG EFFECT; GENETICS; LUNG; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PULMONARY ARTERY; SIGNAL TRANSDUCTION; VASOCONSTRICTION;

ANIMALS; ANOXIA; BONE MORPHOGENETIC PROTEIN RECEPTORS, TYPE II; BONE MORPHOGENETIC PROTEINS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE SUSCEPTIBILITY; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HYPERTENSION, PULMONARY; LUNG; MALE; MICE; MICE, INBRED C57BL; PULMONARY ARTERY; RECEPTORS, SEROTONIN; RNA, MESSENGER; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SIGNAL TRANSDUCTION; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; VASOCONSTRICTION;

EID: 33645751955     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000215809.47923.fd     Document Type: Article

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