-
1
-
-
0023902842
-
Mutants of Caenorhabditis elegans that form dauer-like larvae
-
Albert, P.S. and Riddle, D.L. 1988. Mutants of Caenorhabditis elegans that form dauer-like larvae. Dev. Biol. 126: 270-293.
-
(1988)
Dev. Biol
, vol.126
, pp. 270-293
-
-
Albert, P.S.1
Riddle, D.L.2
-
2
-
-
38649105202
-
Regulation of ceramide biosynthesis by TOR complex 2
-
Aronova, S., Wedaman, K., Aronov, P.A., Fontes, K., Ramos, K., Hammock, B.D., and Powers, T. 2008. Regulation of ceramide biosynthesis by TOR complex 2. Cell Metab. 7: 148-158.
-
(2008)
Cell Metab
, vol.7
, pp. 148-158
-
-
Aronova, S.1
Wedaman, K.2
Aronov, P.A.3
Fontes, K.4
Ramos, K.5
Hammock, B.D.6
Powers, T.7
-
3
-
-
0037448528
-
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
-
Ashrafi, K., Chang, F.Y., Watts, J.L., Fraser, A.G., Kamath, R.S., Ahringer, J., and Ruvkun, G. 2003. Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes. Nature 421: 268-272.
-
(2003)
Nature
, vol.421
, pp. 268-272
-
-
Ashrafi, K.1
Chang, F.Y.2
Watts, J.L.3
Fraser, A.G.4
Kamath, R.S.5
Ahringer, J.6
Ruvkun, G.7
-
4
-
-
0043270437
-
Food transport in the C. elegans pharynx
-
Avery, L. and Shtonda, B.B. 2003. Food transport in the C. elegans pharynx. J. Exp. Biol. 206: 2441-2457.
-
(2003)
J. Exp. Biol
, vol.206
, pp. 2441-2457
-
-
Avery, L.1
Shtonda, B.B.2
-
5
-
-
54849426651
-
Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy
-
Bentzinger, C.F., Romanino, K., Cloetta, D., Lin, S., Mascarenhas, J.B., Oliveri, F., Xia, J., Casanova, E., Costa, C.F., Brink, M., et al. 2008. Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy. Cell Metab. 8: 411-424.
-
(2008)
Cell Metab
, vol.8
, pp. 411-424
-
-
Bentzinger, C.F.1
Romanino, K.2
Cloetta, D.3
Lin, S.4
Mascarenhas, J.B.5
Oliveri, F.6
Xia, J.7
Casanova, E.8
Costa, C.F.9
Brink, M.10
-
6
-
-
34047095297
-
The two TORCs and Akt
-
Bhaskar, P.T. and Hay, N. 2007. The two TORCs and Akt. Dev. Cell 12: 487-502.
-
(2007)
Dev. Cell
, vol.12
, pp. 487-502
-
-
Bhaskar, P.T.1
Hay, N.2
-
7
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. elegans
-
Bishop, N.A. and Guarente, L. 2007. Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447: 545-549.
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
8
-
-
0035135841
-
Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a)
-
Brunet, A., Park, J., Tran, H., Hu, L.S., Hemmings, B.A., and Greenberg, M.E. 2001. Protein kinase SGK mediates survival signals by phosphorylating the forkhead transcription factor FKHRL1 (FOXO3a). Mol. Cell. Biol. 21: 952-965.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 952-965
-
-
Brunet, A.1
Park, J.2
Tran, H.3
Hu, L.S.4
Hemmings, B.A.5
Greenberg, M.E.6
-
9
-
-
0036712770
-
Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure
-
Busjahn, A., Aydin, A., Uhlmann, R., Krasko, C., Bahring, S., Szelestei, T., Feng, Y., Dahm, S., Sharma, A.M., Luft, F.C., et al. 2002. Serum- and glucocorticoid-regulated kinase (SGK1) gene and blood pressure. Hypertension 40: 256-260.
-
(2002)
Hypertension
, vol.40
, pp. 256-260
-
-
Busjahn, A.1
Aydin, A.2
Uhlmann, R.3
Krasko, C.4
Bahring, S.5
Szelestei, T.6
Feng, Y.7
Dahm, S.8
Sharma, A.M.9
Luft, F.C.10
-
10
-
-
47949125486
-
The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C
-
Facchinetti, V., Ouyang, W., Wei, H., Soto, N., Lazorchak, A., Gould, C., Lowry, C., Newton, A.C., Mao, Y., Miao, R.Q., et al. 2008. The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C. EMBO J. 27: 1932-1943.
-
(2008)
EMBO J
, vol.27
, pp. 1932-1943
-
-
Facchinetti, V.1
Ouyang, W.2
Wei, H.3
Soto, N.4
Lazorchak, A.5
Gould, C.6
Lowry, C.7
Newton, A.C.8
Mao, Y.9
Miao, R.Q.10
-
12
-
-
33748471980
-
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s
-
Frias, M.A., Thoreen, C.C., Jaffe, J.D., Schroder, W., Sculley, T., Carr, S.A., and Sabatini, D.M. 2006. mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. Curr. Biol. 16: 1865-1870.
-
(2006)
Curr. Biol
, vol.16
, pp. 1865-1870
-
-
Frias, M.A.1
Thoreen, C.C.2
Jaffe, J.D.3
Schroder, W.4
Sculley, T.5
Carr, S.A.6
Sabatini, D.M.7
-
13
-
-
58649092475
-
mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1)
-
Garcia-Martinez, J.M. and Alessi, D.R. 2008. mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). Biochem. J. 416: 375-385.
-
(2008)
Biochem. J
, vol.416
, pp. 375-385
-
-
Garcia-Martinez, J.M.1
Alessi, D.R.2
-
14
-
-
33751348056
-
Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα, but not S6K1
-
Guertin, D.A., Stevens, D.M., Thoreen, C.C., Burds, A.A., Kalaany, N.Y., Moffat, J., Brown, M., Fitzgerald, K.J., and Sabatini, D.M. 2006. Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCα, but not S6K1. Dev. Cell 11: 859-871.
-
(2006)
Dev. Cell
, vol.11
, pp. 859-871
-
-
Guertin, D.A.1
Stevens, D.M.2
Thoreen, C.C.3
Burds, A.A.4
Kalaany, N.Y.5
Moffat, J.6
Brown, M.7
Fitzgerald, K.J.8
Sabatini, D.M.9
-
15
-
-
11144355021
-
-
Hertweck, M., Gobel, C., and Baumeister, R. 2004. C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev. Cell 6: 577-588.
-
Hertweck, M., Gobel, C., and Baumeister, R. 2004. C. elegans SGK-1 is the critical component in the Akt/PKB kinase complex to control stress response and life span. Dev. Cell 6: 577-588.
-
-
-
-
16
-
-
28844434558
-
mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes
-
Hresko, R.C. and Mueckler, M. 2005. mTOR.RICTOR is the Ser473 kinase for Akt/protein kinase B in 3T3-L1 adipocytes. J. Biol. Chem. 280: 40406-40416.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 40406-40416
-
-
Hresko, R.C.1
Mueckler, M.2
-
17
-
-
38449105152
-
-
Hu P.J. 2007. Dauer. In WormBook (ed. The C. elegans Research Community), WormBook. doi: 10.1895/wormbook.1.144.1 http://www.wormbook.org.
-
Hu P.J. 2007. Dauer. In WormBook (ed. The C. elegans Research Community), WormBook. doi: 10.1895/wormbook.1.144.1 http://www.wormbook.org.
-
-
-
-
18
-
-
4544311861
-
The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span
-
Jia, K., Chen, D., and Riddle, D.L. 2004. The TOR pathway interacts with the insulin signaling pathway to regulate C. elegans larval development, metabolism and life span. Development 131: 3897-3906.
-
(2004)
Development
, vol.131
, pp. 3897-3906
-
-
Jia, K.1
Chen, D.2
Riddle, D.L.3
-
19
-
-
23344448223
-
Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization
-
Kamada, Y., Fujioka, Y., Suzuki, N.N., Inagaki, F., Wullschleger, S., Loewith, R., Hall, M.N., and Ohsumi, Y. 2005. Tor2 directly phosphorylates the AGC kinase Ypk2 to regulate actin polarization. Mol. Cell. Biol. 25: 7239-7248.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 7239-7248
-
-
Kamada, Y.1
Fujioka, Y.2
Suzuki, N.N.3
Inagaki, F.4
Wullschleger, S.5
Loewith, R.6
Hall, M.N.7
Ohsumi, Y.8
-
20
-
-
0038725897
-
Genome-wide RNAi screening in Caenorhabditis elegans
-
Kamath, R.S. and Ahringer, J. 2003. Genome-wide RNAi screening in Caenorhabditis elegans. Methods 30: 313-321.
-
(2003)
Methods
, vol.30
, pp. 313-321
-
-
Kamath, R.S.1
Ahringer, J.2
-
21
-
-
0037448540
-
Systematic functional analysis of the Caeno-rhabditis elegans genome using RNAi
-
Kamath, R.S., Fraser, A.G., Dong, Y., Poulin, G., Durbin, R., Gotta, M., Kanapin, A., Le Bot, N., Moreno, S., Sohrmann, M., et al. 2003. Systematic functional analysis of the Caeno-rhabditis elegans genome using RNAi. Nature 421: 231-237.
-
(2003)
Nature
, vol.421
, pp. 231-237
-
-
Kamath, R.S.1
Fraser, A.G.2
Dong, Y.3
Poulin, G.4
Durbin, R.5
Gotta, M.6
Kanapin, A.7
Le Bot, N.8
Moreno, S.9
Sohrmann, M.10
-
22
-
-
0030813398
-
daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
-
Kimura, K.D., Tissenbaum, H.A., Liu, Y., and Ruvkun, G. 1997. daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
-
(1997)
Science
, vol.277
, pp. 942-946
-
-
Kimura, K.D.1
Tissenbaum, H.A.2
Liu, Y.3
Ruvkun, G.4
-
23
-
-
37549000623
-
Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity
-
Kumar, A., Harris, T.E., Keller, S.R., Choi, K.M., Magnuson, M.A., and Lawrence, Jr., J.C. 2008. Muscle-specific deletion of rictor impairs insulin-stimulated glucose transport and enhances basal glycogen synthase activity. Mol. Cell. Biol. 28: 61-70.
-
(2008)
Mol. Cell. Biol
, vol.28
, pp. 61-70
-
-
Kumar, A.1
Harris, T.E.2
Keller, S.R.3
Choi, K.M.4
Magnuson, M.A.5
Lawrence Jr., J.C.6
-
24
-
-
0035856598
-
Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms
-
doi:10.1126/stke.2001.108.re17
-
Lang, F. and Cohen, P. 2001. Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms. Sci. STKE 2001: RE17. doi:10.1126/stke.2001.108.re17.
-
(2001)
Sci. STKE
, vol.2001
-
-
Lang, F.1
Cohen, P.2
-
25
-
-
33749500123
-
Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms
-
Lang, F., Bohmer, C., Palmada, M., Seebohm, G., Strutz-Seebohm, N., and Vallon, V. 2006. (Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms. Physiol. Rev. 86: 1151-1178.
-
(2006)
Physiol. Rev
, vol.86
, pp. 1151-1178
-
-
Lang, F.1
Bohmer, C.2
Palmada, M.3
Seebohm, G.4
Strutz-Seebohm, N.5
Vallon, V.6
-
26
-
-
34247869955
-
Discrete functions of rictor and raptor in cell growth regulation in Drosophila
-
Lee, G. and Chung, J. 2007. Discrete functions of rictor and raptor in cell growth regulation in Drosophila. Biochem. Biophys. Res. Commun. 357: 1154-1159.
-
(2007)
Biochem. Biophys. Res. Commun
, vol.357
, pp. 1154-1159
-
-
Lee, G.1
Chung, J.2
-
27
-
-
0345447590
-
Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
-
Libina, N., Berman, J.R., and Kenyon, C. 2003. Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115: 489-502.
-
(2003)
Cell
, vol.115
, pp. 489-502
-
-
Libina, N.1
Berman, J.R.2
Kenyon, C.3
-
28
-
-
0037015269
-
TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation
-
Long, X., Spycher, C., Han, Z.S., Rose, A.M., Muller, F., and Avruch, J. 2002. TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. Curr. Biol. 12: 1448-1461.
-
(2002)
Curr. Biol
, vol.12
, pp. 1448-1461
-
-
Long, X.1
Spycher, C.2
Han, Z.S.3
Rose, A.M.4
Muller, F.5
Avruch, J.6
-
29
-
-
0042322370
-
TOR action in mammalian cells and in Caenorhabditis elegans
-
Long, X., Muller, F., and Avruch, J. 2004. TOR action in mammalian cells and in Caenorhabditis elegans. Curr. Top. Microbiol. Immunol. 279: 115-138.
-
(2004)
Curr. Top. Microbiol. Immunol
, vol.279
, pp. 115-138
-
-
Long, X.1
Muller, F.2
Avruch, J.3
-
30
-
-
33644616841
-
Polygenic control of Caenorhabditis elegans fat storage
-
Mak, H.Y., Nelson, L.S., Basson, M., Johnson, C.D., and Ruvkun, G. 2006. Polygenic control of Caenorhabditis elegans fat storage. Nat. Genet. 38: 363-368.
-
(2006)
Nat. Genet
, vol.38
, pp. 363-368
-
-
Mak, H.Y.1
Nelson, L.S.2
Basson, M.3
Johnson, C.D.4
Ruvkun, G.5
-
31
-
-
4344646478
-
Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development
-
McCormick, J.A., Feng, Y., Dawson, K., Behne, M.J., Yu, B., Wang, J., Wyatt, A.W., Henke, G., Grahammer, F., Mauro, T.M., et al. 2004. Targeted disruption of the protein kinase SGK3/CISK impairs postnatal hair follicle development. Mol. Biol. Cell 15: 4278-4288.
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 4278-4288
-
-
McCormick, J.A.1
Feng, Y.2
Dawson, K.3
Behne, M.J.4
Yu, B.5
Wang, J.6
Wyatt, A.W.7
Henke, G.8
Grahammer, F.9
Mauro, T.M.10
-
32
-
-
4344632329
-
Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans
-
Meissner, B., Boll, M., Daniel, H., and Baumeister, R. 2004. Deletion of the intestinal peptide transporter affects insulin and TOR signaling in Caenorhabditis elegans. J. Biol. Chem. 279: 36739-36745.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 36739-36745
-
-
Meissner, B.1
Boll, M.2
Daniel, H.3
Baumeister, R.4
-
33
-
-
0029768753
-
A phos-phatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
-
Morris, J.Z., Tissenbaum, H.A., and Ruvkun, G. 1996. A phos-phatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans. Nature 382: 536-539.
-
(1996)
Nature
, vol.382
, pp. 536-539
-
-
Morris, J.Z.1
Tissenbaum, H.A.2
Ruvkun, G.3
-
34
-
-
0032238299
-
The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway
-
Ogg, S. and Ruvkun, G. 1998. The C. elegans PTEN homolog, DAF-18, acts in the insulin receptor-like metabolic signaling pathway. Mol. Cell 2: 887-893.
-
(1998)
Mol. Cell
, vol.2
, pp. 887-893
-
-
Ogg, S.1
Ruvkun, G.2
-
35
-
-
0030659557
-
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
-
Ogg,S.,Paradis,S.,Gottlieb,S.,Patterson,G.I.,Lee,L.,Tissenbaum, H.A., and Ruvkun, G. 1997. The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389: 994-999.
-
(1997)
Nature
, vol.389
, pp. 994-999
-
-
Ogg, S.1
Paradis, S.2
Gottlieb, S.3
Patterson, G.I.4
Lee, L.5
Tissenbaum, H.A.6
Ruvkun, G.7
-
36
-
-
0032529189
-
Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor
-
Paradis, S. and Ruvkun, G. 1998. Caenorhabditis elegans Akt/PKB transduces insulin receptor-like signals from AGE-1 PI3 kinase to the DAF-16 transcription factor. Genes & Dev. 12: 2488-2498.
-
(1998)
Genes & Dev
, vol.12
, pp. 2488-2498
-
-
Paradis, S.1
Ruvkun, G.2
-
37
-
-
0033151613
-
A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans
-
Paradis, S., Ailion, M., Toker, A., Thomas, J.H., and Ruvkun, G. 1999. A PDK1 homolog is necessary and sufficient to transduce AGE-1 PI3 kinase signals that regulate diapause in Caenorhabditis elegans. Genes & Dev. 13: 1438-1452.
-
(1999)
Genes & Dev
, vol.13
, pp. 1438-1452
-
-
Paradis, S.1
Ailion, M.2
Toker, A.3
Thomas, J.H.4
Ruvkun, G.5
-
38
-
-
0033151832
-
Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway
-
Park, J., Leong, M.L., Buse, P., Maiyar, A.C., Firestone, G.L., and Hemmings, B.A. 1999. Serum and glucocorticoid-inducible kinase (SGK) is a target of the PI 3-kinase-stimulated signaling pathway. EMBO J. 18: 3024-3033.
-
(1999)
EMBO J
, vol.18
, pp. 3024-3033
-
-
Park, J.1
Leong, M.L.2
Buse, P.3
Maiyar, A.C.4
Firestone, G.L.5
Hemmings, B.A.6
-
39
-
-
34347210090
-
Identification of Protor as a novel Rictor-binding component of mTOR complex-2
-
Pearce, L.R., Huang, X., Boudeau, J., Pawlowski, R., Wullschleger, S., Deak, M., Ibrahim, A.F., Gourlay, R., Ma gnuson, M.A., and Alessi, D.R. 2007. Identification of Protor as a novel Rictor-binding component of mTOR complex-2. Biochem. J. 405: 513-522.
-
(2007)
Biochem. J
, vol.405
, pp. 513-522
-
-
Pearce, L.R.1
Huang, X.2
Boudeau, J.3
Pawlowski, R.4
Wullschleger, S.5
Deak, M.6
Ibrahim, A.F.7
Gourlay, R.8
Ma gnuson, M.A.9
Alessi, D.R.10
-
40
-
-
50049117073
-
A 13C isotope labeling strategy reveals the influence of insulin signaling on lipo-genesis in C. elegans
-
Perez, C.L. and Van Gilst, M.R. 2008. A 13C isotope labeling strategy reveals the influence of insulin signaling on lipo-genesis in C. elegans. Cell Metab. 8: 266-274.
-
(2008)
Cell Metab
, vol.8
, pp. 266-274
-
-
Perez, C.L.1
Van Gilst, M.R.2
-
41
-
-
17844377864
-
Insulin signaling in the central nervous system: A critical role in metabolic homeostasis and disease from C. elegans to humans
-
Porte Jr., D. Baskin, D.G., and Schwartz, M.W. 2005. Insulin signaling in the central nervous system: A critical role in metabolic homeostasis and disease from C. elegans to humans. Diabetes 54: 1264-1276.
-
(2005)
Diabetes
, vol.54
, pp. 1264-1276
-
-
Porte Jr., D.1
Baskin, D.G.2
Schwartz, M.W.3
-
42
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak, Y., Peterson, T.R., Shaul, Y.D., Lindquist, R.A., Thoreen, C.C., Bar-Peled, L., and Sabatini, D.M. 2008. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science 320: 1496-1501.
-
(2008)
Science
, vol.320
, pp. 1496-1501
-
-
Sancak, Y.1
Peterson, T.R.2
Shaul, Y.D.3
Lindquist, R.A.4
Thoreen, C.C.5
Bar-Peled, L.6
Sabatini, D.M.7
-
43
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov, D.D., Ali, S.M., Kim, D.H., Guertin, D.A., Latek, R.R., Erdjument-Bromage, H., Tempst, P., and Sabatini, D.M. 2004. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr. Biol. 14: 1296-1302.
-
(2004)
Curr. Biol
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
44
-
-
27544500981
-
Growing roles for the mTOR pathway
-
Sarbassov,D.D.,Ali,S.M.,and Sabatini,D.M.2005a.Growing roles for the mTOR pathway. Curr. Opin. Cell Biol. 17: 596-603.
-
(2005)
Curr. Opin. Cell Biol
, vol.17
, pp. 596-603
-
-
Sarbassov, D.D.1
Ali, S.M.2
Sabatini, D.M.3
-
45
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
Sarbassov, D.D., Guertin, D.A., Ali, S.M., and Sabatini, D.M. 2005b. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307: 1098-1101.
-
(2005)
Science
, vol.307
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
46
-
-
0030479340
-
TOR2 is required for organization of the actin cytoskeleton in yeast
-
Schmidt, A., Kunz, J., and Hall, M.N. 1996. TOR2 is required for organization of the actin cytoskeleton in yeast. Proc. Natl. Acad. Sci. 93: 13780-13785.
-
(1996)
Proc. Natl. Acad. Sci
, vol.93
, pp. 13780-13785
-
-
Schmidt, A.1
Kunz, J.2
Hall, M.N.3
-
47
-
-
33748950810
-
Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability
-
Shiota, C., Woo, J.T., Lindner, J., Shelton, K.D., and Magnuson, M.A. 2006. Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev. Cell 11: 583-589.
-
(2006)
Dev. Cell
, vol.11
, pp. 583-589
-
-
Shiota, C.1
Woo, J.T.2
Lindner, J.3
Shelton, K.D.4
Magnuson, M.A.5
-
48
-
-
31544457058
-
Dietary choice behavior in Caenorhabditis elegans
-
Shtonda, B.B. and Avery, L. 2006. Dietary choice behavior in Caenorhabditis elegans. J. Exp. Biol. 209: 89-102.
-
(2006)
J. Exp. Biol
, vol.209
, pp. 89-102
-
-
Shtonda, B.B.1
Avery, L.2
-
49
-
-
0035823625
-
Distinct transcriptional profiles of adipogenesis in vivo and in vitro
-
Soukas, A., Socci, N.D., Saatkamp, B.D., Novelli, S., and Friedman, J.M. 2001. Distinct transcriptional profiles of adipogenesis in vivo and in vitro. J. Biol. Chem. 276: 34167-34174.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 34167-34174
-
-
Soukas, A.1
Socci, N.D.2
Saatkamp, B.D.3
Novelli, S.4
Friedman, J.M.5
-
50
-
-
33746506061
-
The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation
-
Tabuchi, M., Audhya, A., Parsons, A.B., Boone, C., and Emr, S.D. 2006. The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Mol. Cell. Biol. 26: 5861-5875.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 5861-5875
-
-
Tabuchi, M.1
Audhya, A.2
Parsons, A.B.3
Boone, C.4
Emr, S.D.5
-
51
-
-
40849118472
-
Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans
-
Tullet, J.M., Hertweck, M., An, J.H., Baker, J., Hwang, J.Y., Liu, S., Oliveira, R.P., Baumeister, R., and Blackwell, T.K. 2008. Direct inhibition of the longevity-promoting factor SKN-1 by insulin-like signaling in C. elegans. Cell 132: 1025-1038.
-
(2008)
Cell
, vol.132
, pp. 1025-1038
-
-
Tullet, J.M.1
Hertweck, M.2
An, J.H.3
Baker, J.4
Hwang, J.Y.5
Liu, S.6
Oliveira, R.P.7
Baumeister, R.8
Blackwell, T.K.9
-
52
-
-
0642367846
-
Genetics: Influence of TOR kinase on lifespan in C. elegans
-
doi: 10.1038/426620a
-
Vellai, T., Takacs-Vellai, K., Zhang, Y., Kovacs, A.L., Orosz, L., and Muller, F. 2003. Genetics: Influence of TOR kinase on lifespan in C. elegans. Nature 426: 620. doi: 10.1038/426620a.
-
(2003)
Nature
, vol.426
, pp. 620
-
-
Vellai, T.1
Takacs-Vellai, K.2
Zhang, Y.3
Kovacs, A.L.4
Orosz, L.5
Muller, F.6
-
53
-
-
33751431218
-
The trifecta of aging in Caeno-rhabditis elegans
-
Wolff, S. and Dillin, A. 2006. The trifecta of aging in Caeno-rhabditis elegans. Exp. Gerontol. 41: 894-903.
-
(2006)
Exp. Gerontol
, vol.41
, pp. 894-903
-
-
Wolff, S.1
Dillin, A.2
-
54
-
-
0034613164
-
Regulation of C. elegans life-span by insulinlike signaling in the nervous system
-
Wolkow, C.A., Kimura, K.D., Lee, M.S., and Ruvkun, G. 2000. Regulation of C. elegans life-span by insulinlike signaling in the nervous system. Science 290: 147-150.
-
(2000)
Science
, vol.290
, pp. 147-150
-
-
Wolkow, C.A.1
Kimura, K.D.2
Lee, M.S.3
Ruvkun, G.4
-
55
-
-
33751079895
-
Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity
-
Yang, Q., Inoki, K., Ikenoue, T., and Guan, K.L. 2006. Identification of Sin1 as an essential TORC2 component required for complex formation and kinase activity. Genes & Dev. 20: 2820-2832.
-
(2006)
Genes & Dev
, vol.20
, pp. 2820-2832
-
-
Yang, Q.1
Inoki, K.2
Ikenoue, T.3
Guan, K.L.4
|