Protein homeostasis and aging: Taking care of proteins from the cradle to the grave

Journals of Gerontology - Series A Biological Sciences and Medical Sciences

Volumn 64, Issue 2, 2009, Pages 167-170

  Morimoto, Richard I ^a   Cuervo, Ana M ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

Cellular homeostasis; Chaperones; Proteases; Protein degradation; Protein folding; Proteotoxicity

Indexed keywords

CHAPERONE; FLUORESCENT DYE; PROTEIN; PROTEOME; PROTEASOME;

ADAPTATION; AGING; ALZHEIMER DISEASE; CELL AGING; CELL FUNCTION; CELL STRESS; CELL TYPE; CONFERENCE PAPER; CYTOSOL; CYTOSTASIS; CYTOTOXICITY; DEGENERATIVE DISEASE; ENDOPLASMIC RETICULUM STRESS; ENVIRONMENTAL FACTOR; HOMEOSTASIS; HUMAN; MOLECULAR MECHANICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; OXIDATION; PARKINSON DISEASE; PATHOGENESIS; PHENOTYPE; PHOTOSTIMULATION; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ASSEMBLY; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN PROCESSING; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTEOMICS; REGULATORY MECHANISM; ADULT; AGE; AGED; LONGEVITY; METABOLISM; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; REVIEW; RISK FACTOR;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ALZHEIMER DISEASE; CELL AGING; HOMEOSTASIS; HUMANS; LONGEVITY; NEURODEGENERATIVE DISEASES; OXIDATIVE STRESS; PARKINSON DISEASE; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN FOLDING; PROTEINS; RISK FACTORS;

EID: 64949099855     PISSN: 10795006     EISSN: None     Source Type: Journal    
DOI: 10.1093/gerona/gln071     Document Type: Conference Paper

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