-
1
-
-
0031019855
-
Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression
-
DOI 10.1038/385260a0
-
Hardingham, G. E.; Chawla, S.; Johnson, C. M. Bading, H. Distinct functions of nuclear and cytoplasmic calcium in the control of gene expression. Nature 1997, 385, 260-265. (Pubitemid 27043726)
-
(1997)
Nature
, vol.385
, Issue.6613
, pp. 260-265
-
-
Hardingham, G.E.1
Chawla, S.2
Johnson, C.M.3
Bading, H.4
-
2
-
-
0033858553
-
Transcription-dependent neuronal plasticity the nuclear calcium hypothesis
-
Bading, H. Transcription-dependent neuronal plasticity the nuclear calcium hypothesis. Eur. J. Biochem. 2000, 267, 5280-5283.
-
(2000)
Eur. J. Biochem.
, vol.267
, pp. 5280-5283
-
-
Bading, H.1
-
3
-
-
0035949578
-
Calcium regulation of neuronal gene expression
-
DOI 10.1073/pnas.191352298
-
West, A. E.; Chen, W. G.; Dalva, M. B.; Dolmetsch, R. E.; Kornhauser, J. M.; Shaywitz, A. J.; Takasu, M. A.; Tao, X.; M. E. Greenberg. Calcium regulation of neuronal gene expression. Proc. Natl. Acad. Sci. USA 2001, 98, 11024-11031. (Pubitemid 32928677)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.20
, pp. 11024-11031
-
-
West, A.E.1
Chen, W.G.2
Dalva, M.B.3
Dolmetsch, R.E.4
Kornhauser, J.M.5
Shaywitz, A.J.6
Takasu, M.A.7
Tao, X.8
Greenberg, M.E.9
-
4
-
-
0036902175
-
The contribution of intracellular calcium stores to mEPSCs recorded in layer II neurones of rat barrel cortex
-
DOI 10.1113/jphysiol.2002.022103
-
Simkus, C. R.; Stricker, C. The contribution of intracellular calcium stores to mEPSCs recorded in layer II neurones of rat barrel cortex. J. Physiol. 2002, 545, 521-535. (Pubitemid 36004386)
-
(2002)
Journal of Physiology
, vol.545
, Issue.2
, pp. 521-535
-
-
Simkus, C.R.L.1
Stricker, C.2
-
5
-
-
7444229746
-
Calcium release from presynaptic ryanodine-sensitive stores is required for long-term depression at hippocampal CA3-CA3 pyramidal neuron synapses
-
DOI 10.1523/JNEUROSCI.5583-03.2004
-
Unni, V. K.; Zakharenko, S. S.; Zablow, L.; DeCostanzo, A. J.; Siegelbaum, S. A. Calcium release from presynaptic ryanodine-sensitive stores is required for long-term depression at hippocampal CA3-CA3 pyramidal neuron synapses. J. Neurosci. 2004, 24, 9612-9622. (Pubitemid 39441515)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.43
, pp. 9612-9622
-
-
Unni, V.K.1
Zakharenko, S.S.2
Zablow, L.3
DeCostanzo, A.J.4
Siegelbaum, S.A.5
-
7
-
-
22244471714
-
2+ release modulates synaptic transmission in hippocampal neurons
-
DOI 10.1016/j.molbrainres.2004.12.018
-
2+ release modulates synaptic transmission in hippocampal neurons. Brain Res. Mol. Brain Res. 2005, 135, 232-248. (Pubitemid 40602415)
-
(2005)
Molecular Brain Research
, vol.135
, Issue.1-2
, pp. 232-248
-
-
Kelly, P.T.1
MacKinnon II, R.L.2
Dietz, R.V.3
Maher, B.J.4
Wang, J.5
-
8
-
-
22544446151
-
Presynaptic ryanodine receptors are required for normal quantal size at the Caenorhabditis elegans neuromuscular junction
-
DOI 10.1523/JNEUROSCI.1730-05.2005
-
Liu, Q.; Chen, B.; Yankova, M.; Morest, D. K.; Maryon, E.; Hand, A. R.; Nonet, M. L.; Wang, Z. W. Presynaptic ryanodine receptors are required for normal quantal size at the Caenorhabditis elegans neuromuscular junction. J. Neurosci. 2005, 25, 6745-6754. (Pubitemid 41023142)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.29
, pp. 6745-6754
-
-
Liu, Q.1
Chen, B.2
Yankova, M.3
Morest, D.K.4
Maryon, E.5
Hand, A.R.6
Nonet, M.L.7
Wang, Z.-W.8
-
9
-
-
32544438897
-
Synaptic transmission mediated by internal calcium stores in rod photoreceptors
-
DOI 10.1523/JNEUROSCI.3895-05.2006
-
Suryanarayanan, A.; Slaughter, M. M. Synaptic transmission mediated by internal calcium stores in rod photoreceptors. J. Neurosci. 2006, 26, 1759-1766. (Pubitemid 43236988)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.6
, pp. 1759-1766
-
-
Suryanarayanan, A.1
Slaughter, M.M.2
-
10
-
-
45649084538
-
Calcium release via activation of presynaptic IP3 receptors contributes to kainate-induced IPSC facilitation in rat neocortex
-
Mathew, S. S.; Hablitz, J. J. Calcium release via activation of presynaptic IP3 receptors contributes to kainate-induced IPSC facilitation in rat neocortex. Neuropharmacology 2008, 55, 106-116.
-
(2008)
Neuropharmacology
, vol.55
, pp. 106-116
-
-
Mathew, S.S.1
Hablitz, J.J.2
-
11
-
-
0033059445
-
Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and β-amyloid pathologies
-
DOI 10.1016/S0306-4522(99)00042-1, PII S0306452299000421
-
Kelliher, M.; Fastbom, J.; Cowburn, R. F.; Bonkale, W.; Ohm, T. G.; Ravid, R.; Sorrentino, V.; O'Neill, C. Alterations in the ryanodine receptor calcium release channel correlate with Alzheimer's disease neurofibrillary and beta-amyloid pathologies. Neuroscience 1999, 92, 499-513. (Pubitemid 29268039)
-
(1999)
Neuroscience
, vol.92
, Issue.2
, pp. 499-513
-
-
Kelliher, M.1
Fastbom, J.2
Cowburn, R.F.3
Bonkale, W.4
Ohm, T.G.5
Ravid, R.6
Sorrentino, V.7
O'Neill, C.8
-
12
-
-
4444302167
-
Deranged neuronal calcium signaling and Huntington disease
-
DOI 10.1016/j.bbrc.2004.08.035, PII S0006291X04017735
-
Bezprozvanny, I.; Hayden, M. R. Deranged neuronal calcium signaling and Huntington disease. Biochem. Biophys. Res. Commun. 2004, 322, 1310-1317. (Pubitemid 39164659)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.322
, Issue.4
, pp. 1310-1317
-
-
Bezprozvanny, I.1
Hayden, M.R.2
-
14
-
-
24644460177
-
2+ release in the 3xTg-AD mouse model of Alzheimer's disease
-
DOI 10.1111/j.1471-4159.2005.03332.x
-
2+ release in the 3xTg-AD mouse model of Alzheimer's disease. J. Neurochem. 2005, 94, 1711-1718. (Pubitemid 41324651)
-
(2005)
Journal of Neurochemistry
, vol.94
, Issue.6
, pp. 1711-1718
-
-
Smith, I.F.1
Hitt, B.2
Green, K.N.3
Oddo, S.4
LaFerla, F.M.5
-
15
-
-
14044264256
-
2+ signalling and apoptosis of medium spiny neurons in Huntington's disease
-
DOI 10.1073/pnas.0409402102
-
2+ signaling and apoptosis of medium spiny neurons in Huntington's disease. Proc. Natl. Acad. Sci. USA 2005, 102, 2602-2607. (Pubitemid 40279423)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.7
, pp. 2602-2607
-
-
Tang, T.-S.1
Slow, E.2
Lupu, V.3
Stavrovskaya, I.G.4
Sugimori, M.5
Llinas, R.6
Kristal, B.S.7
Hayden, M.R.8
Bezprozvanny, I.9
-
16
-
-
33747195017
-
An endoplasmic-reticulum-specific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity
-
DOI 10.1016/j.nbd.2006.05.011, PII S0969996106001331
-
Ferreiro, E.; Resende, R.; Costa, R.; Oliveira, C. R.; Pereira, C. M. An endoplasmic-reticulumspecific apoptotic pathway is involved in prion and amyloid-beta peptides neurotoxicity. Neurobiol. Dis. 2006, 23, 669-678. (Pubitemid 44234104)
-
(2006)
Neurobiology of Disease
, vol.23
, Issue.3
, pp. 669-678
-
-
Ferreiro, E.1
Resende, R.2
Costa, R.3
Oliveira, C.R.4
Pereira, C.M.F.5
-
17
-
-
33646886822
-
2+ content in presenilin double knock-out cells
-
DOI 10.1016/j.ceca.2006.03.005, PII S0143416006000510
-
2+ content in presenilin double knock-out cells. Cell Calcium. 2006, 40, 41-51. (Pubitemid 43785820)
-
(2006)
Cell Calcium
, vol.40
, Issue.1
, pp. 41-51
-
-
Kasri, N.N.1
Kocks, S.L.2
Verbert, L.3
Hebert, S.S.4
Callewaert, G.5
Parys, J.B.6
Missiaen, L.7
De Smedt, H.8
-
18
-
-
33846018429
-
Amyloid-β-(1- 42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice
-
DOI 10.1074/jbc.M606736200
-
Supnet, C.; Grant, J.; Kong, H.; Westaway, D.; Mayne, M. Amyloid-beta-(1-42) increases ryanodine receptor-3 expression and function in neurons of TgCRND8 mice. J. Biol. Chem. 2006, 281, 38440-38447. (Pubitemid 46041967)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.50
, pp. 38440-38447
-
-
Supnet, C.1
Grant, J.2
Kong, H.3
Westaway, D.4
Mayne, M.5
-
19
-
-
0023521088
-
Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains
-
Stokes, C. E.; Hawthorne, J. N. Reduced phosphoinositide concentrations in anterior temporal cortex of Alzheimer-diseased brains. J. Neurochem. 1987, 48, 1018-1021.
-
(1987)
J. Neurochem.
, vol.48
, pp. 1018-1021
-
-
Stokes, C.E.1
Hawthorne, J.N.2
-
20
-
-
0023823738
-
Decreased brain [3H]inositol 1,4,5-trisphosphate binding in Alzheimer's disease
-
Young, L. T.; Kish, S. J.; Li, P. P.; Warsh, J. J. Decreased brain [3H]inositol 1,4,5-trisphosphate binding in Alzheimer's disease. Neurosci. Lett. 1988, 94, 198-202.
-
(1988)
Neurosci. Lett.
, vol.94
, pp. 198-202
-
-
Young, L.T.1
Kish, S.J.2
Li, P.P.3
Warsh, J.J.4
-
21
-
-
0027132379
-
Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease
-
Ferrari-DiLeo, G.; Flynn, D. D. Diminished muscarinic receptor-stimulated [3H]-PIP2 hydrolysis in Alzheimer's disease. Life Sci. 1993, 53, 439-444. (Pubitemid 2019042)
-
(1993)
Life Sciences
, vol.53
, Issue.25
, pp. 439-444
-
-
Ferrari-DiLeo, G.1
Flynn, D.D.2
-
22
-
-
0028027552
-
Cholinergic and serotonergic stimulation of phosphoinostide hydrolysis is decreased in Alzheimer's disease
-
DOI 10.1016/0024-3205(94)00379-3
-
Crews, F. T.; Kurian, P.; Freund, G. Cholinergic and serotonergic stimulation of phosphoinositide hydrolysis is decreased in Alzheimer's disease. Life Sci 1994, 55, 1993-2002. (Pubitemid 24372588)
-
(1994)
Life Sciences
, vol.55
, Issue.25-26
, pp. 1993-2002
-
-
Crews, F.T.1
Kurian, P.2
Freund, G.3
-
23
-
-
0028978364
-
Diminished [3H]inositol (1, 4, 5) P3 but not [3H]inositol (1, 3, 4, 5) P4 binding in Alzheimer's disease brain
-
Garlind, A.; Cowburn, R. F.; Forsell, C.; Ravid, R.; Winblad, B.; Fowler, C. J. Diminished [3H]inositol (1, 4, 5) P3 but not [3H]inositol (1, 3, 4, 5) P4 binding in Alzheimer's disease brain. Brain Res. 1995, 681, 160-166.
-
(1995)
Brain Res.
, vol.681
, pp. 160-166
-
-
Garlind, A.1
Cowburn, R.F.2
Forsell, C.3
Ravid, R.4
Winblad, B.5
Fowler, C.J.6
-
24
-
-
0032526841
-
Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology
-
DOI 10.1016/S0006-8993(98)00347-3, PII S0006899398003473
-
Kurumatani, T.; Fastbom, J.; Bonkale, W. L.; Bogdanovic, N.; Winblad, B.; Ohm, T. G.; Cowburn, R. F. Loss of inositol 1,4,5-trisphosphate receptor sites and decreased PKC levels correlate with staging of Alzheimer's disease neurofibrillary pathology. Brain Res. 1998, 796, 209-221. (Pubitemid 28343250)
-
(1998)
Brain Research
, vol.796
, Issue.1-2
, pp. 209-211
-
-
Kurumatani, T.1
Fastbom, J.2
Bonkale, W.L.3
Bogdanovic, N.4
Winblad, B.5
Ohm, T.G.6
Cowburn, R.F.7
-
25
-
-
50249135503
-
Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease
-
Bezprozvanny, I.; Mattson, M. P. Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease. Trends Neurosci. 2008, 31, 454-463.
-
(2008)
Trends Neurosci.
, vol.31
, pp. 454-463
-
-
Bezprozvanny, I.1
Mattson, M.P.2
-
26
-
-
0034674730
-
Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons
-
DOI 10.1074/jbc.M000040200
-
Chan, S. L.; Mayne, M.; Holden, C. P.; Geiger, J. D.; Mattson, M. P. Presenilin-1 mutations increase levels of ryanodine receptors and calcium release in PC12 cells and cortical neurons. J. Biol. Chem. 2000, 275, 18195-18200. (Pubitemid 30414771)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.24
, pp. 18195-18200
-
-
Chan, S.L.1
Mayne, M.2
Holden, C.P.3
Geiger, J.D.4
Mattson, M.P.5
-
27
-
-
35748954015
-
The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity
-
DOI 10.1016/j.biocel.2007.06.023, PII S135727250700218X
-
Rybalchenko, V.; Hwang, S. Y.; Rybalchenko, N.; Koulen, P. The cytosolic N-terminus of presenilin-1 potentiates mouse ryanodine receptor single channel activity. Int. J. Biochem. Cell Biol. 2008, 40, 84-97. (Pubitemid 350052661)
-
(2008)
International Journal of Biochemistry and Cell Biology
, vol.40
, Issue.1
, pp. 84-97
-
-
Rybalchenko, V.1
Hwang, S.-Y.2
Rybalchenko, N.3
Koulen, P.4
-
28
-
-
53549084850
-
The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein-protein interaction
-
Hayrapetyan, V.; Rybalchenko, V.; Rybalchenko, N.; Koulen, P. The N-terminus of presenilin-2 increases single channel activity of brain ryanodine receptors through direct protein-protein interaction. Cell Calcium 2008, 44, 507-518.
-
(2008)
Cell. Calcium.
, vol.44
, pp. 507-518
-
-
Hayrapetyan, V.1
Rybalchenko, V.2
Rybalchenko, N.3
Koulen, P.4
-
29
-
-
34247621471
-
Enhanced ryanodine-mediated calcium release in mutant PS1-expressing Alzheimer's mouse models
-
DOI 10.1196/annals.1379.025, Imaging and the Aging Brain
-
Stutzmann, G. E.; Smith, I.; Caccamo, A.; Oddo, S.; Parker, I.; Laferla, F. Enhanced ryanodinemediated calcium release in mutant PS1-expressing Alzheimer's mouse models. Ann. NY Acad. Sci. 2007, 1097, 265-277. (Pubitemid 47084900)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1097
, pp. 265-277
-
-
Stutzmann, G.E.1
Smith, I.2
Caccamo, A.3
Oddo, S.4
Parker, I.5
Laferla, F.6
-
30
-
-
30744470170
-
PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release
-
Lee, S. Y.; Hwang, D. Y.; Kim, Y. K.; Lee, J. W.; Shin, I. C.; Oh, K. W.; Lee, M. K.; Lim, J. S.; Yoon, D. Y.; Hwang, S. J.; Hong, J. T. PS2 mutation increases neuronal cell vulnerability to neurotoxicants through activation of caspase-3 by enhancing of ryanodine receptor-mediated calcium release. FASEB J. 2006, 20, 151-153.
-
(2006)
FASEB J.
, vol.20
, pp. 151-153
-
-
Lee, S.Y.1
Hwang, D.Y.2
Kim, Y.K.3
Lee, J.W.4
Shin, I.C.5
Oh, K.W.6
Lee, M.K.7
Lim, J.S.8
Yoon, D.Y.9
Hwang, S.J.10
Hong, J.T.11
-
31
-
-
0032704888
-
Presenilin-2 mutations modulate amplitude and kinetics of inositol 1,4,5-trisphosphate-mediated calcium signals
-
Leissring, M. A.; Parker, I.; LaFerla, F. M. Presenilin-2 mutations modulate amplitude and kinetics of inositol 1,4,5-trisphosphate-mediated calcium signals. J. Biol. Chem. 1999, 274, 32535-32538. (Pubitemid 129535275)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.46
, pp. 32535-32538
-
-
Leissring, M.A.1
Parker, I.2
LaFerla, F.M.3
-
32
-
-
45249117227
-
2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating
-
2+ disruption in Alzheimer's disease by presenilin regulation of InsP3 receptor channel gating. Neuron 2008, 58, 871-883.
-
(2008)
Neuron
, vol.58
, pp. 871-883
-
-
Cheung, K.H.1
Shineman, D.2
Muller, M.3
Cardenas, C.4
Mei, L.5
Yang, J.6
Tomita, T.7
Iwatsubo, T.8
Lee, V.M.9
Foskett, J.K.10
-
33
-
-
5444231258
-
Huntingtin processing in pathogenesis of Huntington disease
-
Qin, Z. H.; Gu, Z. L. Huntingtin processing in pathogenesis of Huntington disease. Acta Pharmacol. Sin. 2004, 25, 1243-1249. (Pubitemid 39361794)
-
(2004)
Acta Pharmacologica Sinica
, vol.25
, Issue.10
, pp. 1243-1249
-
-
Qin, Z.-H.1
Gu, Z.-L.2
-
34
-
-
58849103904
-
Targeting oxidative stress for neuroprotection
-
Linseman, D. A. Targeting oxidative stress for neuroprotection. Antioxid. Redox. Signal 2009, 11, 421-424.
-
(2009)
Antioxid. Redox. Signal
, vol.11
, pp. 421-424
-
-
Linseman, D.A.1
-
35
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
DOI 10.1016/0092-8674(93)90585-E
-
The Huntington's Disease Collaborative Research Group. A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72, 971-983. (Pubitemid 23110238)
-
(1993)
Cell
, vol.72
, Issue.6
, pp. 971-983
-
-
MacDonald, M.E.1
Ambrose, C.M.2
Duyao, M.P.3
Myers, R.H.4
Lin, C.5
Srinidhi, L.6
Barnes, G.7
Taylor, S.A.8
James, M.9
Groot, N.10
MacFarlane, H.11
Jenkins, B.12
Anderson, M.A.13
Wexler, N.S.14
Gusella, J.F.15
Bates, G.P.16
Baxendale, S.17
Hummerich, H.18
Kirby, S.19
-
36
-
-
0041963057
-
Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1,4,5) triphosphate receptor type 1
-
DOI 10.1016/S0896-6273(03)00366-0
-
Tang, T. S.; Tu, H.; Chan, E. Y.; Maximov, A.; Wang, Z.; Wellington, C. L.; Hayden, M. R.; Bezprozvanny, I. Huntingtin and huntingtin-associated protein 1 influence neuronal calcium signaling mediated by inositol-(1, 4, 5) triphosphate receptor type 1. Neuron 2003, 39, 227-239. (Pubitemid 36897546)
-
(2003)
Neuron
, vol.39
, Issue.2
, pp. 227-239
-
-
Tang, T.-S.1
Tu, H.2
Chan, E.Y.W.3
Maximov, A.4
Wang, Z.5
Wellington, C.L.6
Hayden, M.R.7
Bezprozvanny, I.8
-
37
-
-
59649118434
-
Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model
-
Tang, T. S.; Guo, C.; Wang, H.; Chen, X.; Bezprozvanny, I. Neuroprotective effects of inositol 1,4,5-trisphosphate receptor C-terminal fragment in a Huntington's disease mouse model. J. Neurosci. 2009, 29, 1257-1266.
-
(2009)
J. Neurosci.
, vol.29
, pp. 1257-1266
-
-
Tang, T.S.1
Guo, C.2
Wang, H.3
Chen, X.4
Bezprozvanny, I.5
-
38
-
-
0037101835
-
Dysregulation of gene expression in the R6/2 model of polyglutamine disease: Parallel changes in muscle and brain
-
Luthi-Carter, R.; Hanson, S. A.; Strand, A. D.; Bergstrom, D. A.; Chun, W.; Peters, N. L.; Woods, A. M.; Chan, E. Y.; Kooperberg, C.; Krainc, D.; Young, A. B.; Tapscott, S. J.; Olson, J. M. Dysregulation of gene expression in the R6/2 model of polyglutamine disease: parallel changes in muscle and brain. Hum. Mol. Genet. 2002, 11, 1911-1926.
-
(2002)
Hum. Mol. Genet.
, vol.11
, pp. 1911-1926
-
-
Luthi-Carter, R.1
Hanson, S.A.2
Strand, A.D.3
Bergstrom, D.A.4
Chun, W.5
Peters, N.L.6
Woods, A.M.7
Chan, E.Y.8
Kooperberg, C.9
Krainc, D.10
Young, A.B.11
Tapscott, S.J.12
Olson, J.M.13
-
39
-
-
65649103331
-
Pathophysiology of neurodegeneration in familial amyotrophic lateral sclerosis
-
Vucic, S.; Kiernan, M. C. Pathophysiology of neurodegeneration in familial amyotrophic lateral sclerosis. Curr. Mol. Med. 2009, 9, 255-272.
-
(2009)
Curr. Mol. Med.
, vol.9
, pp. 255-272
-
-
Vucic, S.1
Kiernan, M.C.2
-
40
-
-
33644829010
-
Calcium signaling pathways mediating synaptic potentiation triggered by amyotrophic lateral sclerosis IgG in motor nerve terminals
-
Pagani, M. R.; Reisin, R. C.; Uchitel, O. D. Calcium signaling pathways mediating synaptic potentiation triggered by amyotrophic lateral sclerosis IgG in motor nerve terminals. J. Neurosci. 2006, 26, 2661-2672.
-
(2006)
J. Neurosci.
, vol.26
, pp. 2661-2672
-
-
Pagani, M.R.1
Reisin, R.C.2
Uchitel, O.D.3
-
42
-
-
4544386279
-
Neuroprotection against ischemic/hypoxic brain damage: Blockers of ionotropic glutamate receptor and voltage sensitive calcium channels
-
DOI 10.2174/1389450043345209
-
Schurr, A. Neuroprotection against ischemic/hypoxic brain damage: Blockers of ionotropic glutamate receptor and voltage sensitive calcium channels. Curr. Drug Targets 2004, 5, 603-618. (Pubitemid 39242869)
-
(2004)
Current Drug Targets
, vol.5
, Issue.7
, pp. 603-618
-
-
Schurr, A.1
-
43
-
-
38849139200
-
Calcium channelopathies: Voltage-gated calcium channels
-
Adams, P. J.; Snutch, T. P. Calcium channelopathies: Voltage-gated calcium channels. Subcell Biochem. 2007, 45, 215-251.
-
(2007)
Subcell Biochem.
, vol.45
, pp. 215-251
-
-
Adams, P.J.1
Snutch, T.P.2
-
44
-
-
0029810979
-
Functional coupling between ryanodine receptors and L-type calcium channels in neurons
-
DOI 10.1038/382719a0
-
Chavis, P.; Fagni, L.; Lansman, J. B.; Bockaert, J. Functional coupling between ryanodine receptors and L-type calcium channels in neurons. Nature 1996, 382, 719-722. (Pubitemid 26282178)
-
(1996)
Nature
, vol.382
, Issue.6593
, pp. 719-722
-
-
Chavis, P.1
Fagni, L.2
Lansman, J.B.3
Bockaert, J.4
-
45
-
-
0035868325
-
Molecular interaction of dihydropyridine receptors with type-1 ryanodine receptors in rat brain
-
DOI 10.1042/0264-6021:3540597
-
Mouton, J.; Marty, I.; Villaz, M.; Feltz, A.; Maulet, Y. Molecular interaction of dihydropyridine receptors with type-1 ryanodine receptors in rat brain. Biochem. J. 2001, 354, 597-603. (Pubitemid 32269723)
-
(2001)
Biochemical Journal
, vol.354
, Issue.3
, pp. 597-603
-
-
Mouton, J.1
Marty, I.2
Villaz, M.3
Feltz, A.4
Maulet, Y.5
-
46
-
-
0030497661
-
Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage
-
DOI 10.1016/S0028-3908(96)00104-9, PII S0028390896001049
-
Krieglstein, J.; Lippert, K.; Poch, G. Apparent independent action of nimodipine and glutamate antagonists to protect cultured neurons against glutamate-induced damage. Neuropharmacology 1996, 35, 1737-1742. (Pubitemid 27090792)
-
(1996)
Neuropharmacology
, vol.35
, Issue.12
, pp. 1737-1742
-
-
Krieglstein, J.1
Lippert, K.2
Poch, G.3
-
47
-
-
0031564645
-
Identification of calcium channels involved in neuronal injury in rat hippocampal slices subjected to oxygen and glucose deprivation
-
DOI 10.1016/S0006-8993(96)01385-6, PII S0006899396013856
-
Small, D. L.; Monette, R.; Buchan, A. M.; Morley, P. Identification of calcium channels involved in neuronal injury in rat hippocampal slices subjected to oxygen and glucose deprivation. Brain Res. 1997, 753, 209-218. (Pubitemid 27151865)
-
(1997)
Brain Research
, vol.753
, Issue.2
, pp. 209-218
-
-
Small, D.L.1
Monette, R.2
Buchan, A.M.3
Morley, P.4
-
48
-
-
0024579338
-
Improvement of cortical perfusion, intracellular pH, and electrocorticography by nimodipine during transient focal cerebral ischemia
-
Tally, P. W.; Sundt, T. M.; Anderson, R. E. Improvement of cortical perfusion, intracellular pH, and electrocorticography by nimodipine during transient focal cerebral ischemia. Neurosurgery 1989, 24, 80-87.
-
(1989)
Neurosurgery
, vol.24
, pp. 80-87
-
-
Tally, P.W.1
Sundt, T.M.2
Anderson, R.E.3
-
49
-
-
0025663403
-
Diverse mechanisms of neuronal protection by nimodipine in experimental rabbit brain ischemia
-
Lazarewicz, J. W.; Pluta, R.; Puka, M.; Salinska, E. Diverse mechanisms of neuronal protection by nimodipine in experimental rabbit brain ischemia. Stroke 1990, 21, IV108-110.
-
(1990)
Stroke
, vol.21
-
-
Lazarewicz, J.W.1
Pluta, R.2
Puka, M.3
Salinska, E.4
-
50
-
-
0025793975
-
The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis
-
Ohta, S.; Smith, M. L.; Siesjo, B. K. The effect of a dihydropyridine calcium antagonist (isradipine) on selective neuronal necrosis. J. Neurol. Sci. 1991, 103, 109-115.
-
(1991)
J. Neurol. Sci.
, vol.103
, pp. 109-115
-
-
Ohta, S.1
Smith, M.L.2
Siesjo, B.K.3
-
51
-
-
0028853701
-
2+ antagonist nimodipine, influence of aging and developmental drug treatment
-
2+ antagonist nimodipine, influence of aging and developmental drug treatment. Neurodegeneration 1995, 4, 307-314.
-
(1995)
Neurodegeneration
, vol.4
, pp. 307-314
-
-
Luiten, P.G.1
Douma, B.R.2
Van Der Zee, E.A.3
Nyakas, C.4
-
52
-
-
0031266451
-
Effects of Isradipine, an L-Type Calcium Channel Blocker on Permanent and Transient Focal Cerebral Ischemia in Spontaneously Hypertensive Rats
-
Campbell, C. A.; Mackay, K. B.; Patel, S.; King, P. D.; Stretton, J. L.; Hadingham, S. J.; Hamilton, T. C. Effects of isradipine, an L-type calcium channel blocker on permanent and transient focal cerebral ischemia in spontaneously hypertensive rats. Exp. Neurol. 1997, 148, 45-50. (Pubitemid 127445113)
-
(1997)
Experimental Neurology
, vol.148
, Issue.1
, pp. 45-50
-
-
Campbell, C.A.1
Mackay, K.B.2
Patel, S.3
King, P.D.4
Stretton, J.L.5
Hadingham, S.J.6
Hamilton, T.C.7
-
53
-
-
0030700570
-
Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model
-
Kittaka, M.; Giannotta, S. L.; Zelman, V.; Correale, J. D.; DeGiorgio, C. M.; Weiss, M. H.; Zlokovic, B. V. Attenuation of brain injury and reduction of neuron-specific enolase by nicardipine in systemic circulation following focal ischemia and reperfusion in a rat model. J. Neurosurg. 1997, 87, 731-737. (Pubitemid 27454592)
-
(1997)
Journal of Neurosurgery
, vol.87
, Issue.5
, pp. 731-737
-
-
Kittaka, M.1
Giannotta, S.L.2
Zelman, V.3
Correale, J.D.4
DeGiorgio, C.M.5
Weiss, M.H.6
Zlokovic, B.V.7
-
54
-
-
0030784933
-
Neuroprotection by the novel calcium antagonist PCA50938, nimodipine and flunarizine, in gerbil global brain ischemia
-
DOI 10.1016/S0006-8993(97)00838-X, PII S000689939700838X
-
Zapater, P.; Moreno, J.; Horga, J. F. Neuroprotection by the novel calcium antagonist PCA50938, nimodipine and flunarizine, in gerbil global brain ischemia. Brain Res. 1997, 772, 57-62. (Pubitemid 27501683)
-
(1997)
Brain Research
, vol.772
, Issue.1-2
, pp. 57-62
-
-
Zapater, P.1
Moreno, J.2
Horga, J.F.3
-
55
-
-
0032966764
-
Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia
-
DOI 10.1159/000028294
-
Chandra, S.; White, R. F.; Everding, D.; Feuerstein, G. Z.; Coatney, R. W.; Sarkar, S. K.; Barone, F. C. Use of diffusion-weighted MRI and neurological deficit scores to demonstrate beneficial effects of isradipine in a rat model of focal ischemia. Pharmacology 1999, 58, 292-299. (Pubitemid 29206184)
-
(1999)
Pharmacology
, vol.58
, Issue.6
, pp. 292-299
-
-
Chandra, S.1
White, R.F.2
Everding, D.3
Feuerstein, G.Z.4
Coatney, R.W.5
Sarkar, S.K.6
Barone, F.C.7
-
56
-
-
0034792905
-
Nimodipine in animal model experiments of focal cerebral ischemia: A systematic review
-
Horn, J.; de Haan, R. J.; Vermeulen, M.; Luiten, P. G.; Limburg, M. Nimodipine in animal model experiments of focal cerebral ischemia: A systematic review. Stroke 2001, 32, 2433-2438. (Pubitemid 32954819)
-
(2001)
Stroke
, vol.32
, Issue.10
, pp. 2433-2438
-
-
Horn, J.1
De Haan, R.J.2
Vermeulen, M.3
Luiten, P.G.M.4
Limburg, M.5
-
57
-
-
2542424800
-
Treatment with nicardipine protects brain in an animal model of hypertension-induced damage
-
DOI 10.1081/CEH-120034139
-
Amenta, F.; Tomassoni, D. Treatment with Nicardipine Protects Brain in an Animal Model of Hypertension-Induced Damage. Clin. Exp. Hypertens. 2004, 26, 351-361. (Pubitemid 38691116)
-
(2004)
Clinical and Experimental Hypertension
, vol.26
, Issue.4
, pp. 351-361
-
-
Amenta, F.1
Tomassoni, D.2
-
58
-
-
0028886705
-
Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia
-
Bailey, S. J.; Wood, N. I.; Samson, N. A.; Rothaul, A. L.; Roberts, J. C.; King, P. D.; Hamilton, T. C.; Harrison, D. C.; Hunter, A. J. Failure of isradipine to reduce infarct size in mouse, gerbil, and rat models of cerebral ischemia. Stroke 1995, 26, 2177-2183.
-
(1995)
Stroke
, vol.26
, pp. 2177-2183
-
-
Bailey, S.J.1
Wood, N.I.2
Samson, N.A.3
Rothaul, A.L.4
Roberts, J.C.5
King, P.D.6
Hamilton, T.C.7
Harrison, D.C.8
Hunter, A.J.9
-
59
-
-
48849089052
-
Neuroprotection for ischemic stroke: Past, present and future
-
Ginsberg, M. D. Neuroprotection for ischemic stroke: Past, present and future. Neuropharmacology 2008, 55, 363-389.
-
(2008)
Neuropharmacology
, vol.55
, pp. 363-389
-
-
Ginsberg, M.D.1
-
60
-
-
0242694942
-
Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation
-
Stevens, T. R.; Krueger, S. R.; Fitzsimonds, R. M.; Picciotto, M. R. Neuroprotection by nicotine in mouse primary cortical cultures involves activation of calcineurin and L-type calcium channel inactivation. J. Neurosci. 2003, 23, 10093-10099.
-
(2003)
J. Neurosci.
, vol.23
, pp. 10093-10099
-
-
Stevens, T.R.1
Krueger, S.R.2
Fitzsimonds, R.M.3
Picciotto, M.R.4
-
61
-
-
0035144882
-
Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons
-
Brewer, L. D.; Thibault, V.; Chen, K. C.; Langub, M. C.; Landfield, P. W.; Porter, N. M. Vitamin D hormone confers neuroprotection in parallel with downregulation of L-type calcium channel expression in hippocampal neurons. J. Neurosci. 2001, 21, 98-108. (Pubitemid 32098731)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.1
, pp. 98-108
-
-
Brewer, L.D.1
Thibault, V.2
Chen, K.-C.3
Langub, M.C.4
Landfield, P.W.5
Porter, N.M.6
-
62
-
-
70350654526
-
Phoneutria spider toxins block ischemia-induced glutamate release, neuronal death, and loss of neurotransmission in hippocampus
-
Pinheiro, A. C.; da Silva, A. J.; Prado, M. A.; Cordeiro, M. D.; Richardson, M.; Batista, M. C.; de Castro Junior, C. J.; Massensini, A. R.; Guatimosim, C.; Romano-Silva, M. A.; Kushmerick, C.; Gomez, M. V. Phoneutria spider toxins block ischemia-induced glutamate release, neuronal death, and loss of neurotransmission in hippocampus. Hippocampus 2009, 19, 1123-1129.
-
(2009)
Hippocampus
, vol.19
, pp. 1123-1129
-
-
Pinheiro, A.C.1
Da Silva, A.J.2
Prado, M.A.3
Cordeiro, M.D.4
Richardson, M.5
Batista, M.C.6
De Castro Jr., C.C.7
Massensini, A.R.8
Guatimosim, C.9
Romano-Silva, M.A.10
Kushmerick, C.11
Gomez, M.V.12
-
63
-
-
33746911210
-
Neuroprotective effect on brain injury by neurotoxins from the spider Phoneutria nigriventer
-
DOI 10.1016/j.neuint.2006.04.009, PII S0197018606001732
-
Pinheiro, A. C. N.; Gomez, R. S.; Massensini, A. R.; Cordeiro, M. N.; Richardson, M.; Romano-Silva, M. A.; Prado, M. A. M.; Marco, L. D.; Gomez, M. V. Neuroprotective effect on brain injury by neurotoxins from the spider Phoneutria nigriventer. Neurochem. Int. 2006, 49, 543-547. (Pubitemid 44192597)
-
(2006)
Neurochemistry International
, vol.49
, Issue.5
, pp. 543-547
-
-
Pinheiro, A.C.N.1
Gomez, R.S.2
Massensini, A.R.3
Cordeiro, M.N.4
Richardson, M.5
Romano-Silva, M.A.6
Prado, M.A.M.7
Marco, L.D.8
Gomez, M.V.9
-
64
-
-
49449083916
-
New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties
-
León, R.; Ríos, C.d.l.; Marco-Contelles, J.; Huertas, O.; Barril, X.; Javier Luque, F.; López, M. G.; García, A. G.; Villarroya, M. New tacrine-dihydropyridine hybrids that inhibit acetylcholinesterase, calcium entry, and exhibit neuroprotection properties. Bioorg. Medicinal Chem. 2008, 16, 7759-7769.
-
(2008)
Bioorg. Medicinal Chem.
, vol.16
, pp. 7759-7769
-
-
León, R.1
Ríos, C.2
Marco-Contelles, J.3
Huertas, O.4
Barril, X.5
Luque, J.F.6
López, M.G.7
García, A.G.8
Villarroya, M.9
-
65
-
-
0042536473
-
Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity
-
DOI 10.1016/S0143-4160(03)00141-6
-
Arundine, M.; Tymianski, M. Molecular mechanisms of calcium-dependent neurodegeneration in excitotoxicity. Cell Calcium 2003, 34, 325-337. (Pubitemid 37021228)
-
(2003)
Cell Calcium
, vol.34
, Issue.4-5
, pp. 325-337
-
-
Arundine, M.1
Tymianski, M.2
-
66
-
-
13544268511
-
N-methyl-D-aspartate receptor subtypes: Multiple roles in excitotoxicity and neurological disease
-
Waxman, E. A.; Lynch, D. R. N-methyl-D-aspartate receptor subtypes: Multiple roles in excitotoxicity and neurological disease. Neuroscientist 2005, 11, 37-49.
-
(2005)
Neuroscientist
, vol.11
, pp. 37-49
-
-
Waxman, E.A.1
Lynch, D.R.2
-
67
-
-
34249085665
-
NMDA and AMPA receptors: old channels, new tricks
-
DOI 10.1016/j.tins.2007.03.012, PII S016622360700077X
-
Rao, V. R.; Finkbeiner, S. NMDA and AMPA receptors: Old channels, new tricks. Trends Neurosci. 2007, 30, 284-291. (Pubitemid 46802833)
-
(2007)
Trends in Neurosciences
, vol.30
, Issue.6
, pp. 284-291
-
-
Rao, V.R.1
Finkbeiner, S.2
-
68
-
-
0028327506
-
Stimulation of NMDA receptors activates calpain in cultured hippocampal slices
-
DOI 10.1016/0304-3940(94)91049-9
-
del Cerro, S.; Arai, A.; Kessler, M.; Bahr, B. A.; Vanderklish, P.; Rivera, S.; Lynch, G. Stimulation of NMDA receptors activates calpain in cultured hippocampal slices. Neurosci. Lett. 1994, 167, 149-152. (Pubitemid 24077661)
-
(1994)
Neuroscience Letters
, vol.167
, Issue.1-2
, pp. 149-152
-
-
Del Cerro, S.1
Arai, A.2
Kessler, M.3
Bahr, B.A.4
Vanderklish, P.5
Rivera, S.6
Lynch, G.7
-
69
-
-
48949120457
-
Glutamatergic calcium dynamics and deregulation of rat retinal ganglion cells
-
Hartwick, A. T.; Hamilton, C. M.; Baldridge, W. H. Glutamatergic calcium dynamics and deregulation of rat retinal ganglion cells. J. Physiol. 2008, 586, 3425-3446.
-
(2008)
J. Physiol.
, vol.586
, pp. 3425-3446
-
-
Hartwick, A.T.1
Hamilton, C.M.2
Baldridge, W.H.3
-
70
-
-
70349103713
-
Memantine: A review of its use in moderate to severe Alzheimer's disease
-
McKeage, K. Memantine: A review of its use in moderate to severe Alzheimer's disease. CNS Drugs 2009, 23, 881-897.
-
(2009)
CNS Drugs
, vol.23
, pp. 881-897
-
-
McKeage, K.1
-
71
-
-
77950350271
-
Memantine: A review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias
-
Thomas, S. J.; Grossberg, G. T. Memantine: A review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias. Clin. Interv. Aging. 2009, 4, 367-377.
-
(2009)
Clin. Interv. Aging
, vol.4
, pp. 367-377
-
-
Thomas, S.J.1
Grossberg, G.T.2
-
72
-
-
0029098659
-
Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
-
Kornau, H. C.; Schenker, L. T.; Kennedy, M. B.; Seeburg, P. H. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 1995, 269, 1737-1740.
-
(1995)
Science
, vol.269
, pp. 1737-1740
-
-
Kornau, H.C.1
Schenker, L.T.2
Kennedy, M.B.3
Seeburg, P.H.4
-
73
-
-
0030200438
-
Heteromultimerization and NMDA receptor-clustering activity of Chapsyn- 110, a member of the PSD-95 family of proteins
-
DOI 10.1016/S0896-6273(00)80284-6
-
Kim, E.; Cho, K. O.; Rothschild, A.; Sheng, M. Heteromultimerization and NMDA receptorclustering activity of Chapsyn-110, a member of the PSD-95 family of proteins. Neuron 1996, 17, 103-113. (Pubitemid 26251595)
-
(1996)
Neuron
, vol.17
, Issue.1
, pp. 103-113
-
-
Kim, E.1
Cho, K.-O.2
Rothschild, A.3
Sheng, M.4
-
74
-
-
0029946167
-
Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
-
Niethammer, M.; Kim, E.; Sheng, M. Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases. J. Neurosci. 1996, 16, 2157-2163. (Pubitemid 26154327)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.7
, pp. 2157-2163
-
-
Niethammer, M.1
Kim, E.2
Sheng, M.3
-
75
-
-
0030900558
-
GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
-
DOI 10.1038/386279a0
-
Dong, H.; O'Brien, R. J.; Fung, E. T.; Lanahan, A. A.; Worley, P. F.; Huganir, R. L. GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors. Nature 1997, 386, 279-284. (Pubitemid 27142513)
-
(1997)
Nature
, vol.386
, Issue.6622
, pp. 279-284
-
-
Dong, H.1
O'Brien, R.J.2
Fung, E.T.3
Lanahan, A.A.4
Worley, P.F.5
Huganir, R.L.6
-
76
-
-
0343729350
-
Loss of postsynaptic GABA(A) receptor clustering in gephyrin-deficient mice
-
Kneussel, M.; Brandstatter, J. H.; Laube, B.; Stahl, S.; Muller, U.; Betz, H. Loss of postsynaptic GABA (A) receptor clustering in gephyrin-deficient mice. J. Neurosci. 1999, 19, 9289-9297. (Pubitemid 30228082)
-
(1999)
Journal of Neuroscience
, vol.19
, Issue.21
, pp. 9289-9297
-
-
Kneussel, M.1
Brandstatter, J.H.2
Laube, B.3
Stahl, S.4
Muller, U.5
Betz, H.6
-
77
-
-
0032907948
-
Clustering of AMPA receptors by the synaptic PD domain-containing protein PICK1
-
DOI 10.1016/S0896-6273(00)80689-3
-
Xia, J.; Zhang, X.; Staudinger, J.; Huganir, R. L. Clustering of AMPA receptors by the synaptic PDZ domain-containing protein PICK1. Neuron 1999, 22, 179-187. (Pubitemid 29070104)
-
(1999)
Neuron
, vol.22
, Issue.1
, pp. 179-187
-
-
Xia, J.1
Zhang, X.2
Staudinger, J.3
Huganir, R.L.4
-
78
-
-
0034523581
-
PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKC-dependent regulation of AMPA receptors at hippocampal synapses
-
DOI 10.1016/S0896-6273(00)00160-4
-
Daw, M. I.; Chittajallu, R.; Bortolotto, Z. A.; Dev, K. K.; Duprat, F.; Henley, J. M.; Collingridge, G. L.; Isaac, J. T. PDZ proteins interacting with C-terminal GluR2/3 are involved in a PKCdependent regulation of AMPA receptors at hippocampal synapses. Neuron 2000, 28, 873-886. (Pubitemid 32038078)
-
(2000)
Neuron
, vol.28
, Issue.3
, pp. 873-886
-
-
Daw, M.I.1
Chittajallu, R.2
Bortolotto, Z.A.3
Dev, K.K.4
Duprat, F.5
Henley, J.M.6
Collingridge, G.L.7
Isaac, J.T.R.8
-
79
-
-
0035083006
-
Enrichment of N-methyl-D-aspartate NR1 splice variants and synaptic proteins in rat postsynaptic densities
-
Al-Hallaq, R. A.; Yasuda, R. P.; Wolfe, B. B. Enrichment of N-methyl-D-aspartate NR1 splice variants and synaptic proteins in rat postsynaptic densities. J. Neurochem. 2001, 77, 110-119.
-
(2001)
J. Neurochem.
, vol.77
, pp. 110-119
-
-
Al-Hallaq, R.A.1
Yasuda, R.P.2
Wolfe, B.B.3
-
80
-
-
0037456522
-
Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP
-
DOI 10.1016/S0896-6273(02)01191-1
-
Hirbec, H.; Francis, J. C.; Lauri, S. E.; Braithwaite, S. P.; Coussen, F.; Mulle, C.; Dev, K. K.; Coutinho, V.; Meyer, G.; Isaac, J. T.; Collingridge, G. L.; Henley, J. M. Rapid and differential regulation of AMPA and kainate receptors at hippocampal mossy fibre synapses by PICK1 and GRIP. Neuron 2003, 37, 625-638. (Pubitemid 36262984)
-
(2003)
Neuron
, vol.37
, Issue.4
, pp. 625-638
-
-
Hirbec, H.1
Francis, J.C.2
Lauri, S.E.3
Braithwaite, S.P.4
Coussen, F.5
Mulle, C.6
Dev, K.K.7
Couthino, V.8
Meyer, G.9
Isaac, J.T.R.10
Collingridge, G.L.11
Henley, J.M.12
-
81
-
-
0038794104
-
Synapse-associated protein-97 isoform-specific regulation of surface AMPA receptors and synaptic function in cultured neurons
-
Rumbaugh, G.; Sia, G. M.; Garner, C. C.; Huganir, R. L. Synapse-associated protein-97 isoformspecific regulation of surface AMPA receptors and synaptic function in cultured neurons. J. Neurosci. 2003, 23, 4567-4576. (Pubitemid 36706187)
-
(2003)
Journal of Neuroscience
, vol.23
, Issue.11
, pp. 4567-4576
-
-
Rumbaugh, G.1
Sia, G.-M.2
Garner, C.C.3
Huganir, R.L.4
-
82
-
-
15444362199
-
Calcium-permeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF
-
DOI 10.1016/j.neuron.2005.02.026
-
Gardner, S. M.; Takamiya, K.; Xia, J.; Suh, J. G.; Johnson, R.; Yu, S.; Huganir, R. L. Calciumpermeable AMPA receptor plasticity is mediated by subunit-specific interactions with PICK1 and NSF. Neuron 2005, 45, 903-915. (Pubitemid 40395268)
-
(2005)
Neuron
, vol.45
, Issue.6
, pp. 903-915
-
-
Gardner, S.M.1
Takamiya, K.2
Xia, J.3
Suh, J.-G.4
Johnson, R.5
Yu, S.6
Huganir, R.L.7
-
83
-
-
25144522326
-
PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking
-
DOI 10.1038/sj.emboj.7600801, PII 7600801
-
Hanley, J. G.; Henley, J. M. PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking. EMBO J. 2005, 24, 3266-3278. (Pubitemid 41348701)
-
(2005)
EMBO Journal
, vol.24
, Issue.18
, pp. 3266-3278
-
-
Hanley, J.G.1
Henley, J.M.2
-
84
-
-
22844449702
-
2+ permeability of AMPARs at cerebellar synapses
-
2+ permeability of AMPARs at cerebellar synapses. Nat. Neurosci. 2005, 8, 768-775.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 768-775
-
-
Liu, S.J.1
Cull-Candy, S.G.2
-
85
-
-
35548956067
-
The role of the PDZ protein GIPC in regulating NMDA receptor trafficking
-
DOI 10.1523/JNEUROSCI.3252-07.2007
-
Yi, Z.; Petralia, R. S.; Fu, Z.; Swanwick, C. C.; Wang, Y. X.; Prybylowski, K.; Sans, N.; Vicini, S.; Wenthold, R. J. The role of the PDZ protein GIPC in regulating NMDA receptor trafficking. J. Neurosci. 2007, 27, 11663-11675. (Pubitemid 350006895)
-
(2007)
Journal of Neuroscience
, vol.27
, Issue.43
, pp. 11663-11675
-
-
Yi, Z.1
Petralia, R.S.2
Fu, Z.3
Swanwick, C.C.4
Wang, Y.-X.5
Prybylowski, K.6
Sans, N.7
Vicini, S.8
Wenthold, R.J.9
-
86
-
-
0027232729
-
Kainate elicits elevated nuclear calcium signals in retinal neurons via calcium-induced calcium release
-
Kocsis, J. D.; Rand, M. N.; Chen, B.; Waxman, S. G.; Pourcho, R. Kainate elicits elevated nuclear calcium signals in retinal neurons via calcium-induced calcium release. Brain Res. 1993, 616, 273-282. (Pubitemid 23200056)
-
(1993)
Brain Research
, vol.616
, Issue.1-2
, pp. 273-282
-
-
Kocsis, J.D.1
Rand, M.N.2
Chen, B.3
Waxman, S.G.4
Pourcho, R.5
-
87
-
-
0031905889
-
N-methyl-D-aspartate receptor-mediated, calcium-induced calcium release in rat dentate gyrus/CA4 in vivo
-
DOI 10.1002/(SICI)1097-4547(19980101)51:1<76::AID-JNR8>3.0.CO;2-I
-
Lazarewicz, J. W.; Rybkowski, W.; Sadowski, M.; Ziembowicz, A.; Alaraj, M.; Wegiel, J.; Wisniewski, H. M. N-methyl-D-aspartate receptor-mediated, calcium-induced calcium release in rat dentate gyrus/CA4 in vivo. J. Neurosci. Res. 1998, 51, 76-84. (Pubitemid 28063150)
-
(1998)
Journal of Neuroscience Research
, vol.51
, Issue.1
, pp. 76-84
-
-
Lazarewicz, J.W.1
Rybkowski, W.2
Sadowski, M.3
Ziembowicz, A.4
Alaraj, M.5
Wegiel, J.6
Wisniewski, H.M.7
-
88
-
-
0032930964
-
Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines
-
DOI 10.1016/S0896-6273(00)80683-2
-
Emptage, N.; Bliss, T. V.; Fine, A. Single synaptic events evoke NMDA receptor-mediated release of calcium from internal stores in hippocampal dendritic spines. Neuron 1999, 22, 115-124. (Pubitemid 29070098)
-
(1999)
Neuron
, vol.22
, Issue.1
, pp. 115-124
-
-
Emptage, N.1
Bliss, T.V.P.2
Fine, A.3
-
89
-
-
0037198591
-
Age-dependent occurrence of synchronized population oscillation suggestive of a developing functional coupling between NMDA and ryanodine receptors in the neocortex
-
DOI 10.1016/S0165-3806(02)00352-8, PII S0165380602003528
-
Yoshimura, H.; Sugai, T.; Onoda, N.; Segami, N.; Kato, N. Age-dependent occurrence of synchronized population oscillation suggestive of a developing functional coupling between NMDA and ryanodine receptors in the neocortex. Brain Res. Dev. Brain. Res. 2002, 136, 63-68. (Pubitemid 34556985)
-
(2002)
Developmental Brain Research
, vol.136
, Issue.1
, pp. 63-68
-
-
Yoshimura, H.1
Sugai, T.2
Onoda, N.3
Segami, N.4
Kato, N.5
-
90
-
-
10344242039
-
Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 is regulated by actin filaments and 4.1N in neuronal dendrites
-
DOI 10.1074/jbc.M408364200
-
Fukatsu, K.; Bannai, H.; Zhang, S.; Nakamura, H.; Inoue, T.; Mikoshiba, K. Lateral diffusion of inositol 1,4,5-trisphosphate receptor type 1 is regulated by actin filaments and 4.1N in neuronal dendrites. J. Biol. Chem. 2004, 279, 48976-48982. (Pubitemid 39625779)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.47
, pp. 48976-48982
-
-
Fukatsu, K.1
Bannai, H.2
Zhang, S.3
Nakamura, H.4
Inoue, T.5
Mikoshiba, K.6
-
91
-
-
0036678723
-
Endoplasmic reticulum calcium release is modulated by actin polymerization
-
Wang, Y.; Mattson, M. P.; Furukawa, K. Endoplasmic reticulum calcium release is modulated by actin polymerization. J. Neurochem. 2002, 82, 945-952.
-
(2002)
J. Neurochem.
, vol.82
, pp. 945-952
-
-
Wang, Y.1
Mattson, M.P.2
Furukawa, K.3
-
93
-
-
58149518066
-
The actin cytoskeleton differentially regulates NG115-401L cell ryanodine receptor and inositol 1,4,5-trisphosphate receptor induced calcium signaling pathways
-
Bose, D. D.; Thomas, D. W. The actin cytoskeleton differentially regulates NG115-401L cell ryanodine receptor and inositol 1,4,5-trisphosphate receptor induced calcium signaling pathways. Biochem. Biophys. Res. Commun. 2009, 379, 594-599.
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.379
, pp. 594-599
-
-
Bose, D.D.1
Thomas, D.W.2
-
94
-
-
0032054473
-
Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: Differential attachment of NMDA versus AMPA receptors
-
Allison, D. W.; Gelfand, V. I.; Spector, I.; Craig, A. M. Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: Differential attachment of NMDA versus AMPA receptors. J. Neurosci. 1998, 18, 2423-2436.
-
(1998)
J. Neurosci.
, vol.18
, pp. 2423-2436
-
-
Allison, D.W.1
Gelfand, V.I.2
Spector, I.3
Craig, A.M.4
-
95
-
-
0035503064
-
Regulation of NMDA receptor activity by F-actin and myosin light chain kinase
-
Lei, S.; Czerwinska, E.; Czerwinski, W.; Walsh, M. P.; MacDonald, J. F. Regulation of NMDA receptor activity by F-actin and myosin light chain kinase. J. Neurosci. 2001, 21, 8464-8472.
-
(2001)
J. Neurosci.
, vol.21
, pp. 8464-8472
-
-
Lei, S.1
Czerwinska, E.2
Czerwinski, W.3
Walsh, M.P.4
MacDonald, J.F.5
-
96
-
-
0034004473
-
Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity
-
Sattler, R.; Xiong, Z.; Lu, W. Y.; MacDonald, J. F.; Tymianski, M. Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity. J. Neurosci. 2000, 20, 22-33.
-
(2000)
J. Neurosci.
, vol.20
, pp. 22-33
-
-
Sattler, R.1
Xiong, Z.2
Lu, W.Y.3
MacDonald, J.F.4
Tymianski, M.5
-
97
-
-
0037130451
-
Subunit-specific NMDA receptor trafficking to synapses
-
Barria, A.; Malinow, R. Subunit-specific NMDA receptor trafficking to synapses. Neuron 2002, 35, 345-353.
-
(2002)
Neuron
, vol.35
, pp. 345-353
-
-
Barria, A.1
Malinow, R.2
-
98
-
-
23044445669
-
Regulation of NMDA receptor trafficking by amyloid-beta
-
Snyder, E. M.; Nong, Y.; Almeida, C. G.; Paul, S.; Moran, T.; Choi, E. Y.; Nairn, A. C.; Salter, M. W.; Lombroso, P. J.; Gouras, G. K.; Greengard, P. Regulation of NMDA receptor trafficking by amyloid-beta. Nat. Neurosci. 2005, 8, 1051-1058.
-
(2005)
Nat. Neurosci.
, vol.8
, pp. 1051-1058
-
-
Snyder, E.M.1
Nong, Y.2
Almeida, C.G.3
Paul, S.4
Moran, T.5
Choi, E.Y.6
Nairn, A.C.7
Salter, M.W.8
Lombroso, P.J.9
Gouras, G.K.10
Greengard, P.11
-
99
-
-
26944467176
-
Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses
-
Almeida, C. G.; Tampellini, D.; Takahashi, R. H.; Greengard, P.; Lin, M. T.; Snyder, E. M.; Gouras, G. K. Beta-amyloid accumulation in APP mutant neurons reduces PSD-95 and GluR1 in synapses. Neurobiol. Dis. 2005, 20, 187-198.
-
(2005)
Neurobiol. Dis.
, vol.20
, pp. 187-198
-
-
Almeida, C.G.1
Tampellini, D.2
Takahashi, R.H.3
Greengard, P.4
Lin, M.T.5
Snyder, E.M.6
Gouras, G.K.7
-
100
-
-
33845883324
-
Synapse-specific regulation of AMPA receptor function by PSD-95
-
Beique, J. C.; Lin, D. T.; Kang, M. G.; Aizawa, H.; Takamiya, K.; Huganir, R. L. Synapse-specific regulation of AMPA receptor function by PSD-95. Proc. Natl. Acad. Sci. USA 2006, 103, 19535-19540.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 19535-19540
-
-
Beique, J.C.1
Lin, D.T.2
Kang, M.G.3
Aizawa, H.4
Takamiya, K.5
Huganir, R.L.6
-
101
-
-
12144271690
-
The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death
-
Cao, J.; Viholainen, J. I.; Dart, C.; Warwick, H. K.; Leyland, M. L.; Courtney, M. J. The PSD95-nNOS interface: A target for inhibition of excitotoxic p38 stress-activated protein kinase activation and cell death. J. Cell Biol. 2005, 168, 117-126.
-
(2005)
J. Cell. Biol.
, vol.168
, pp. 117-126
-
-
Cao, J.1
Viholainen, J.I.2
Dart, C.3
Warwick, H.K.4
Leyland, M.L.5
Courtney, M.J.6
-
102
-
-
0033546347
-
Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
-
Sattler, R.; Xiong, Z.; Lu, W. Y.; Hafner, M.; MacDonald, J. F.; Tymianski, M. Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 1999, 284, 1845-1848.
-
(1999)
Science
, vol.284
, pp. 1845-1848
-
-
Sattler, R.1
Xiong, Z.2
Lu, W.Y.3
Hafner, M.4
MacDonald, J.F.5
Tymianski, M.6
-
103
-
-
33947314641
-
Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway
-
Shankar, G. M.; Bloodgood, B. L.; Townsend, M.; Walsh, D. M.; Selkoe, D. J.; Sabatini, B. L. Natural oligomers of the Alzheimer amyloid-beta protein induce reversible synapse loss by modulating an NMDA-type glutamate receptor-dependent signaling pathway. J. Neurosci. 2007, 27, 2866-2875.
-
(2007)
J. Neurosci.
, vol.27
, pp. 2866-2875
-
-
Shankar, G.M.1
Bloodgood, B.L.2
Townsend, M.3
Walsh, D.M.4
Selkoe, D.J.5
Sabatini, B.L.6
-
104
-
-
33845411954
-
AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss
-
Hsieh, H.; Boehm, J.; Sato, C.; Iwatsubo, T.; Tomita, T.; Sisodia, S.; Malinow, R. AMPAR removal underlies Abeta-induced synaptic depression and dendritic spine loss. Neuron 2006, 52, 831-843.
-
(2006)
Neuron
, vol.52
, pp. 831-843
-
-
Hsieh, H.1
Boehm, J.2
Sato, C.3
Iwatsubo, T.4
Tomita, T.5
Sisodia, S.6
Malinow, R.7
-
105
-
-
0344672942
-
APP processing and synaptic function
-
Kamenetz, F.; Tomita, T.; Hsieh, H.; Seabrook, G.; Borchelt, D.; Iwatsubo, T.; Sisodia, S.; Malinow, R. APP processing and synaptic function. Neuron 2003, 37, 925-937.
-
(2003)
Neuron
, vol.37
, pp. 925-937
-
-
Kamenetz, F.1
Tomita, T.2
Hsieh, H.3
Seabrook, G.4
Borchelt, D.5
Iwatsubo, T.6
Sisodia, S.7
Malinow, R.8
-
106
-
-
70449729604
-
PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma
-
Bell, J. D.; Park, E.; Ai, J.; Baker, A. J. PICK1-mediated GluR2 endocytosis contributes to cellular injury after neuronal trauma. Cell Death Differ. 2009, 16, 1665-1680.
-
(2009)
Cell. Death Differ.
, vol.16
, pp. 1665-1680
-
-
Bell, J.D.1
Park, E.2
Ai, J.3
Baker, A.J.4
-
107
-
-
0028296276
-
Modulation of muscarinic cholinoceptorstimulated inositol 1,4,5-trisphosphate accumulation by N-methyl-D-aspartate in neonatal rat cerebral cortex
-
Challis, R. A.; Mistry, R.; Gray, D. W.; Nahorski, S. R. Modulation of muscarinic cholinoceptorstimulated inositol 1,4,5-trisphosphate accumulation by N-methyl-D-aspartate in neonatal rat cerebral cortex. Neuropharmacology 1994, 33, 15-25.
-
(1994)
Neuropharmacology
, vol.33
, pp. 15-25
-
-
Challis, R.A.1
Mistry, R.2
Gray, D.W.3
Nahorski, S.R.4
-
108
-
-
9844238709
-
2+ oscillation in cultured rat frontal cortical neurons
-
2+ oscillation in cultured rat frontal cortical neurons. J. Neural. Transm. 1997, 104, 811-824.
-
(1997)
J. Neural. Transm.
, vol.104
, pp. 811-824
-
-
Hayashi, T.1
Kagaya, A.2
Takebayashi, M.3
Oyamada, T.4
Inagaki, M.5
Tawara, Y.6
Yokota, N.7
Horiguchi, J.8
Su, T.P.9
Yamawaki, S.10
-
109
-
-
3042561726
-
NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons
-
Young, K. W.; Garro, M. A.; Challiss, R. A.; Nahorski, S. R. NMDA-receptor regulation of muscarinic-receptor stimulated inositol 1,4,5-trisphosphate production and protein kinase C activation in single cerebellar granule neurons. J. Neurochem. 2004, 89, 1537-1546.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1537-1546
-
-
Young, K.W.1
Garro, M.A.2
Challiss, R.A.3
Nahorski, S.R.4
-
110
-
-
30444440163
-
NMDA receptor-mediated epileptiform persistent activity requires calcium release from intracellular stores in prefrontal neurons
-
Gao, W. J.; Goldman-Rakic, P. S. NMDA receptor-mediated epileptiform persistent activity requires calcium release from intracellular stores in prefrontal neurons. Exp. Neurol. 2006, 197, 495-504.
-
(2006)
Exp. Neurol.
, vol.197
, pp. 495-504
-
-
Gao, W.J.1
Goldman-Rakic, P.S.2
-
111
-
-
0026071055
-
Inositol trisphosphate receptor: Phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles
-
Ferris, C. D.; Huganir, R. L.; Bredt, D. S.; Cameron, A. M.; Snyder, S. H. Inositol trisphosphate receptor: Phosphorylation by protein kinase C and calcium calmodulin-dependent protein kinases in reconstituted lipid vesicles. Proc Natl. Acad. Sci. USA 1991, 88, 2232-2235.
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 2232-2235
-
-
Ferris, C.D.1
Huganir, R.L.2
Bredt, D.S.3
Cameron, A.M.4
Snyder, S.H.5
-
112
-
-
0026089312
-
Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation
-
Takasago, T.; Imagawa, T.; Furukawa, K.; Ogurusu, T.; Shigekawa, M. Regulation of the cardiac ryanodine receptor by protein kinase-dependent phosphorylation. J. Biochem. 1991, 109, 163-170.
-
(1991)
J. Biochem.
, vol.109
, pp. 163-170
-
-
Takasago, T.1
Imagawa, T.2
Furukawa, K.3
Ogurusu, T.4
Shigekawa, M.5
-
113
-
-
0028089680
-
Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from skeletal muscle
-
Hain, J.; Nath, S.; Mayrleitner, M.; Fleischer, S.; Schindler, H. Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from skeletal muscle. Biophys. J. 1994, 67, 1823-1833.
-
(1994)
Biophys. J.
, vol.67
, pp. 1823-1833
-
-
Hain, J.1
Nath, S.2
Mayrleitner, M.3
Fleischer, S.4
Schindler, H.5
-
114
-
-
0030915445
-
Transforming growth factor-beta1 inhibits type I inositol 1,4,5-trisphosphate receptor expression and enhances its phosphorylation in mesangial cells
-
Sharma, K.; Wang, L.; Zhu, Y.; Bokkala, S.; Joseph, S. K. Transforming growth factor-beta1 inhibits type I inositol 1,4,5-trisphosphate receptor expression and enhances its phosphorylation in mesangial cells. J. Biol. Chem. 1997, 272, 14617-14623.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 14617-14623
-
-
Sharma, K.1
Wang, L.2
Zhu, Y.3
Bokkala, S.4
Joseph, S.K.5
-
115
-
-
0007191908
-
Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells
-
Wojcikiewicz, R. J.; Luo, S. G. Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells. J. Biol. Chem. 1998, 273, 5670-5677.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 5670-5677
-
-
Wojcikiewicz, R.J.1
Luo, S.G.2
-
117
-
-
2942529018
-
Regulation of the phosphorylation of the inositol 1,4,5-trisphosphate receptor by protein kinase C
-
DOI 10.1016/j.bbrc.2004.05.071, PII S0006291X04010630
-
Vermassen, E.; Fissore, R. A.; Nadif Kasri, N.; Vanderheyden, V.; Callewaert, G.; Missiaen, L.; Parys, J. B.; De Smedt, H. Regulation of the phosphorylation of the inositol 1,4,5-trisphosphate receptor by protein kinase C. Biochem. Biophys. Res. Commun. 2004, 319, 888-893. (Pubitemid 38739404)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.319
, Issue.3
, pp. 888-893
-
-
Vermassen, E.1
Fissore, R.A.2
Kasri, N.N.3
Vanderheyden, V.4
Callewaert, G.5
Missiaen, L.6
Parys, J.B.7
Smedt, H.D.8
-
118
-
-
3042763171
-
2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor
-
2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circ. Res. 2004, 94, e61-e70.
-
(2004)
Circ. Res.
, vol.94
-
-
Wehrens, X.H.1
Lehnart, S.E.2
Reiken, S.R.3
Marks, A.R.4
-
119
-
-
33747882331
-
Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase
-
DOI 10.1016/j.bbrc.2006.07.208, PII S0006291X06017669
-
Bai, G. R.; Yang, L. H.; Huang, X. Y.; Sun, F. Z. Inositol 1,4,5-trisphosphate receptor type 1 phosphorylation and regulation by extracellular signal-regulated kinase. Biochem. Biophys. Res. Commun. 2006, 348, 1319-1327. (Pubitemid 44291346)
-
(2006)
Biochemical and Biophysical Research Communications
, vol.348
, Issue.4
, pp. 1319-1327
-
-
Bai, G.-R.1
Yang, L.-H.2
Huang, X.-Y.3
Sun, F.-Z.4
-
120
-
-
33645642577
-
Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors
-
DOI 10.1074/jbc.M509262200
-
Khan, M. T.; Wagner, L., 2nd; Yule, D. I.; Bhanumathy, C.; Joseph, S. K. Akt kinase phosphorylation of inositol 1,4,5-trisphosphate receptors. J. Biol. Chem. 2006, 281, 3731-3737. (Pubitemid 43845991)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.6
, pp. 3731-3737
-
-
Khan, M.T.1
Wagner II, L.2
Yule, D.I.3
Bhanumathy, C.4
Joseph, S.K.5
-
121
-
-
33748795034
-
ERK binds, phosphorylates InsP3 type 1 receptor and regulates intracellular calcium dynamics in DT40 cells
-
Yang, L. H.; Bai, G. R.; Huang, X. Y.; Sun, F. Z. ERK binds, phosphorylates InsP3 type 1 receptor and regulates intracellular calcium dynamics in DT40 cells. Biochem. Biophys. Res. Commun. 2006, 349, 1339-1344.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.349
, pp. 1339-1344
-
-
Yang, L.H.1
Bai, G.R.2
Huang, X.Y.3
Sun, F.Z.4
-
122
-
-
33947406460
-
2+ in pancreatoma AR4-2J cells
-
DOI 10.1677/JOE-06-0179
-
2+in pancreatoma AR4-2J cells. J. Endocrinol. 2007, 192, 659-668. (Pubitemid 46455968)
-
(2007)
Journal of Endocrinology
, vol.192
, Issue.3
, pp. 659-668
-
-
Arguin, G.1
Regimbald-Dumas, Y.2
Fregeau, M.-O.3
Caron, A.Z.4
Guillemette, G.5
-
123
-
-
33947416509
-
Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells
-
DOI 10.1016/j.ceca.2007.01.002, PII S0143416007000085
-
Caron, A. Z.; Chaloux, B.; Arguin, G.; Guillemette, G. Protein kinase C decreases the apparent affinity of the inositol 1,4,5-trisphosphate receptor type 3 in RINm5F cells. Cell Calcium. 2007, 42, 323-331. (Pubitemid 47074403)
-
(2007)
Cell Calcium
, vol.42
, Issue.3
, pp. 323-331
-
-
Caron, A.Z.1
Chaloux, B.2
Arguin, G.3
Guillemette, G.4
-
124
-
-
38549095165
-
Progesterone potentiates IP (3) -mediated calcium signaling through Akt/PKB
-
Koulen, P.; Madry, C.; Duncan, R. S.; Hwang, J. Y.; Nixon, E.; McClung, N.; Gregg, E. V.; Singh, M. Progesterone potentiates IP (3) -mediated calcium signaling through Akt/PKB. Cell Physiol. Biochem. 2008, 21, 161-172.
-
(2008)
Cell. Physiol. Biochem.
, vol.21
, pp. 161-172
-
-
Koulen, P.1
Madry, C.2
Duncan, R.S.3
Hwang, J.Y.4
Nixon, E.5
McClung, N.6
Gregg, E.V.7
Singh, M.8
-
125
-
-
61449169005
-
Progesterone potentiates calcium release through IP3 receptors by an Akt-mediated mechanism in hippocampal neurons
-
Hwang, J. Y.; Duncan, R. S.; Madry, C.; Singh, M.; Koulen, P. Progesterone potentiates calcium release through IP3 receptors by an Akt-mediated mechanism in hippocampal neurons. Cell Calcium 2009, 45, 233-242.
-
(2009)
Cell. Calcium.
, vol.45
, pp. 233-242
-
-
Hwang, J.Y.1
Duncan, R.S.2
Madry, C.3
Singh, M.4
Koulen, P.5
-
126
-
-
18544393408
-
Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins
-
Xiao, B.; Tu, J. C.; Petralia, R. S.; Yuan, J. P.; Doan, A.; Breder, C. D.; Ruggiero, A.; Lanahan, A. A.; Wenthold, R. J.; Worley, P. F. Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of homer-related, synaptic proteins. Neuron 1998, 21, 707-716.
-
(1998)
Neuron
, vol.21
, pp. 707-716
-
-
Xiao, B.1
Tu, J.C.2
Petralia, R.S.3
Yuan, J.P.4
Doan, A.5
Breder, C.D.6
Ruggiero, A.7
Lanahan, A.A.8
Wenthold, R.J.9
Worley, P.F.10
-
127
-
-
0033165926
-
Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin
-
Naisbitt, S.; Kim, E.; Tu, J. C.; Xiao, B.; Sala, C.; Valtschanoff, J.; Weinberg, R. J.; Worley, P. F.; Sheng, M. Shank, a novel family of postsynaptic density proteins that binds to the NMDA receptor/PSD-95/GKAP complex and cortactin. Neuron 1999, 23, 569-582.
-
(1999)
Neuron
, vol.23
, pp. 569-582
-
-
Naisbitt, S.1
Kim, E.2
Tu, J.C.3
Xiao, B.4
Sala, C.5
Valtschanoff, J.6
Weinberg, R.J.7
Worley, P.F.8
Sheng, M.9
-
128
-
-
0033166537
-
Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins
-
Tu, J. C.; Xiao, B.; Naisbitt, S.; Yuan, J. P.; Petralia, R. S.; Brakeman, P.; Doan, A.; Aakalu, V. K.; Lanahan, A. A.; Sheng, M.; Worley, P. F. Coupling of mGluR/Homer and PSD-95 complexes by the Shank family of postsynaptic density proteins. Neuron 1999, 23, 583-592.
-
(1999)
Neuron
, vol.23
, pp. 583-592
-
-
Tu, J.C.1
Xiao, B.2
Naisbitt, S.3
Yuan, J.P.4
Petralia, R.S.5
Brakeman, P.6
Doan, A.7
Aakalu, V.K.8
Lanahan, A.A.9
Sheng, M.10
Worley, P.F.11
-
129
-
-
0034879863
-
Regulation of dendritic spine morphology and synaptic function by Shank and Homer
-
DOI 10.1016/S0896-6273(01)00339-7
-
Sala, C.; Piech, V.; Wilson, N. R.; Passafaro, M.; Liu, G.; Sheng, M. Regulation of dendritic spine morphology and synaptic function by Shank and Homer. Neuron 2001, 31, 115-130. (Pubitemid 32757093)
-
(2001)
Neuron
, vol.31
, Issue.1
, pp. 115-130
-
-
Sala, C.1
Piech, V.2
Wilson, N.R.3
Passafaro, M.4
Liu, G.5
Sheng, M.6
-
130
-
-
0023062991
-
G proteins: Transducers of receptor-generated signals
-
Gilman, A. G. G proteins: Transducers of receptor-generated signals. Annu. Rev. Biochem. 1987, 56, 615-649.
-
(1987)
Annu. Rev. Biochem.
, vol.56
, pp. 615-649
-
-
Gilman, A.G.1
-
131
-
-
0025834532
-
Diversity of G proteins in signal transduction
-
Simon, M. I.; Strathmann, M. P.; Gautam, N. Diversity of G proteins in signal transduction. Science 1991, 252, 802-808.
-
(1991)
Science
, vol.252
, pp. 802-808
-
-
Simon, M.I.1
Strathmann, M.P.2
Gautam, N.3
-
132
-
-
66249144426
-
The structure and function of G-proteincoupled receptors
-
Rosenbaum, D. M.; Rasmussen, S. G.; Kobilka, B. K. The structure and function of G-proteincoupled receptors. Nature 2009, 459, 356-363.
-
(2009)
Nature
, vol.459
, pp. 356-363
-
-
Rosenbaum, D.M.1
Rasmussen, S.G.2
Kobilka, B.K.3
-
133
-
-
37549016836
-
Heterotrimeric G protein activation by G-protein-coupled receptors
-
Oldham, W. M.; Hamm, H. E. Heterotrimeric G protein activation by G-protein-coupled receptors. Nat. Rev. Mol. Cell Biol. 2008, 9, 60-71.
-
(2008)
Nat. Rev. Mol. Cell. Biol.
, vol.9
, pp. 60-71
-
-
Oldham, W.M.1
Hamm, H.E.2
-
134
-
-
34547157646
-
Siderovski, Receptor-mediated activation of heterotrimeric Gproteins: Current structural insights
-
Johnston, C. A.; Siderovski, D. P. Siderovski, Receptor-mediated activation of heterotrimeric Gproteins: Current structural insights. Mol. Pharmacol. 2007, 72, 219-230.
-
(2007)
Mol. Pharmacol.
, vol.72
, pp. 219-230
-
-
Johnston, C.A.1
Siderovski, D.P.2
-
135
-
-
60149088035
-
Functions and Regulatory Mechanisms of Gq-Signaling Pathways
-
Mizuno, N.; Itoh, H. Functions and Regulatory Mechanisms of Gq-Signaling Pathways. Neurosignals 2009, 17, 42-54.
-
(2009)
Neurosignals
, vol.17
, pp. 42-54
-
-
Mizuno, N.1
Itoh, H.2
-
136
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane, W. A.; Hanus, L.; Breuer, A.; Pertwee, R. G.; Stevenson, L. A.; Griffin, G.; Gibson, D.; Mandelbaum, A.; Etinger, A.; Mechoulam, R. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science 1992, 258, 1946-1949.
-
(1992)
Science
, vol.258
, pp. 1946-1949
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
Pertwee, R.G.4
Stevenson, L.A.5
Griffin, G.6
Gibson, D.7
Mandelbaum, A.8
Etinger, A.9
Mechoulam, R.10
-
137
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam, R.; Ben-Shabat, S.; Hanus, L.; Ligumsky, M.; Kaminski, N. E.; Schatz, A. R.; Gopher, A.; Almog, S.; Martin, B. R.; Compton, D. R.; Pertwee, R. G.; Griffin, G.; Bayewitch, M.; Barg, J.; Vogel, Z. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 1995, 50, 83-90.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 83-90
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
Ligumsky, M.4
Kaminski, N.E.5
Schatz, A.R.6
Gopher, A.7
Almog, S.8
Martin, B.R.9
Compton, D.R.10
Pertwee, R.G.11
Griffin, G.12
Bayewitch, M.13
Barg, J.14
Vogel, Z.15
-
138
-
-
0028970517
-
2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain
-
Sugiura, T.; Kondo, S.; Sukagawa, A.; Nakane, S.; Shinoda, A.; Itoh, K.; Yamashita, A.; Waku, K. 2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain. Biochem. Biophys. Res. Commun. 1995, 215, 89-97.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 89-97
-
-
Sugiura, T.1
Kondo, S.2
Sukagawa, A.3
Nakane, S.4
Shinoda, A.5
Itoh, K.6
Yamashita, A.7
Waku, K.8
-
139
-
-
70349339642
-
Novel endogenous peptide agonists of cannabinoid receptors
-
Gomes, I.; Grushko, J. S.; Golebiewska, U.; Hoogendoorn, S.; Gupta, A.; Heimann, A. S.; Ferro, E. S.; Scarlata, S.; Fricker, L. D.; Devi, L. A. Novel endogenous peptide agonists of cannabinoid receptors. FASEB J. 2009, 23, 3020-3029.
-
(2009)
FASEB J.
, vol.23
, pp. 3020-3029
-
-
Gomes, I.1
Grushko, J.S.2
Golebiewska, U.3
Hoogendoorn, S.4
Gupta, A.5
Heimann, A.S.6
Ferro, E.S.7
Scarlata, S.8
Fricker, L.D.9
Devi, L.A.10
-
140
-
-
0021722983
-
Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes
-
Howlett, A. C.; Fleming, R. M. Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes. Mol. Pharmacol. 1984, 26, 532-538.
-
(1984)
Mol. Pharmacol.
, vol.26
, pp. 532-538
-
-
Howlett, A.C.1
Fleming, R.M.2
-
141
-
-
18444376760
-
International Union of Pharmacology. XXVII. Classification of cannabinoid receptors
-
DOI 10.1124/pr.54.2.161
-
Howlett, A. C.; Barth, F.; Bonner, T. I.; Cabral, G.; Casellas, P.; Devane, W. A.; Felder, C. C.; Herkenham, M.; Mackie, K.; Martin, B. R.; Mechoulam, R.; Pertwee, R. G. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol. Rev. 2002, 54, 161-202. (Pubitemid 34575709)
-
(2002)
Pharmacological Reviews
, vol.54
, Issue.2
, pp. 161-202
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
Cabral, G.4
Casellas, P.5
Devane, W.A.6
Felder, C.C.7
Herkenham, M.8
Mackie, K.9
Martin, B.R.10
Mechoulam, R.11
Pertwee, R.G.12
-
142
-
-
0030746408
-
Cannabinoids inhibit n- and p/q-type calcium channels in cultured rat hippocampal neurons
-
Twitchell, W.; Brown, S.; Mackie, K. Cannabinoids inhibit N-and P/Q-type calcium channels in cultured rat hippocampal neurons. J. Neurophysiol. 1997, 78, 43-50. (Pubitemid 27318909)
-
(1997)
Journal of Neurophysiology
, vol.78
, Issue.1
, pp. 43-50
-
-
Twitchell, W.1
Brown, S.2
Mackie, K.3
-
143
-
-
0026603679
-
Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells
-
Mackie, K.; Hille, B. Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells. Proc. Natl. Acad. Sci. USA 1992, 89, 3825-3829.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 3825-3829
-
-
Mackie, K.1
Hille, B.2
-
144
-
-
0027185227
-
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
-
Felder, C. C.; Briley, E. M.; Axelrod, J.; Simpson, J. T.; Mackie, K.; Devane, W. A. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. USA 1993, 90, 7656-7660.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7656-7660
-
-
Felder, C.C.1
Briley, E.M.2
Axelrod, J.3
Simpson, J.T.4
Mackie, K.5
Devane, W.A.6
-
145
-
-
33749648816
-
Cannabinoid receptor-mediated inhibition of calcium signaling in rat retinal ganglion cells
-
Lalonde, M. R.; Jollimore, C. A.; Stevens, K.; Barnes, S.; Kelly, M. E. Cannabinoid receptormediated inhibition of calcium signaling in rat retinal ganglion cells. Mol. Vis. 2006, 12, 1160-1166. (Pubitemid 44538153)
-
(2006)
Molecular Vision
, vol.12
, pp. 1160-1166
-
-
Lalonde, M.R.1
Jollimore, C.A.B.2
Stevens, K.3
Barnes, S.4
Kelly, M.E.M.5
-
146
-
-
30044435435
-
The cannabinoid agonist WIN55, 212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins
-
Lauckner, J. E.; Hille, B.; Mackie, K. The cannabinoid agonist WIN55, 212-2 increases intracellular calcium via CB1 receptor coupling to Gq/11 G proteins. Proc. Natl. Acad. Sci. USA 2005, 102, 19144-19149.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 19144-19149
-
-
Lauckner, J.E.1
Hille, B.2
Mackie, K.3
-
147
-
-
0035979606
-
1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity
-
DOI 10.1016/S0304-3940(01)02065-1, PII S0304394001020651
-
Abood, M. E.; Rizvi, G.; Sallapudi, N.; McAllister, S. D. Activation of the CB1 cannabinoid receptor protects cultured mouse spinal neurons against excitotoxicity. Neurosci. Lett. 2001, 309, 197-201. (Pubitemid 32763173)
-
(2001)
Neuroscience Letters
, vol.309
, Issue.3
, pp. 197-201
-
-
Abood, M.E.1
Rizvi, G.2
Sallapudi, N.3
McAllister, S.D.4
-
148
-
-
33846066404
-
Thayer, Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity
-
Gilbert, G. L.; Kim, H. J.; Waataja, J. J.; Thayer, S. A. Thayer, Delta9-tetrahydrocannabinol protects hippocampal neurons from excitotoxicity. Brain Res. 2007, 1128, 61-69.
-
(2007)
Brain Res.
, vol.1128
, pp. 61-69
-
-
Gilbert, G.L.1
Kim, H.J.2
Waataja, J.J.3
Thayer, S.A.4
-
149
-
-
0031914157
-
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission
-
Hampson, A. J.; Bornheim, L. M.; Scanziani, M.; Yost, C. S.; Gray, A. T.; Hansen, B. M.; Leonoudakis, D. J.; Bickler, P. E. Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J. Neurochem. 1998, 70, 671-676. (Pubitemid 28079356)
-
(1998)
Journal of Neurochemistry
, vol.70
, Issue.2
, pp. 671-676
-
-
Hampson, A.J.1
Bornheim, L.M.2
Scanziani, M.3
Yost, C.S.4
Gray, A.T.5
Hansen, B.M.6
Leonoudakis, D.J.7
Bickler, P.E.8
-
150
-
-
0031706164
-
Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity
-
Shen, M.; Thayer, S. A. Thayer, Cannabinoid receptor agonists protect cultured rat hippocampal neurons from excitotoxicity. Mol. Pharmacol. 1998, 54, 459-462. (Pubitemid 28442938)
-
(1998)
Molecular Pharmacology
, vol.54
, Issue.3
, pp. 459-462
-
-
Shen, M.1
Thayer, S.A.2
-
151
-
-
73349099368
-
Signaling pathways from CB1 receptor activation to inhibition of NMDA-mediated calcium influx and neurotoxicity in dorsal root ganglion neurons
-
Liu, Q.; Bhat, M.; Bowen, W. D.; Cheng, J. Signaling pathways from CB1 receptor activation to inhibition of NMDA-mediated calcium influx and neurotoxicity in dorsal root ganglion neurons. J. Pharmacol. Exp. Ther. 2009, 331, 1062-1070.
-
(2009)
J. Pharmacol. Exp. Ther.
, vol.331
, pp. 1062-1070
-
-
Liu, Q.1
Bhat, M.2
Bowen, W.D.3
Cheng, J.4
-
152
-
-
0029937282
-
Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures
-
Shen, M.; Piser, T. M.; Seybold, V. S.; Thayer, S. A. Cannabinoid receptor agonists inhibit glutamatergic synaptic transmission in rat hippocampal cultures. J. Neurosci. 1996, 16, 4322-4334. (Pubitemid 26243028)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.14
, pp. 4322-4334
-
-
Shen, M.1
Piser, T.M.2
Seybold, V.S.3
Thayer, S.A.4
-
153
-
-
33644837127
-
Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity
-
DOI 10.1124/mol.105.016428
-
Kim, S. H.; Won, S. J.; Mao, X. O.; Jin, K.; Greenberg, D. A. Molecular mechanisms of cannabinoid protection from neuronal excitotoxicity. Mol. Pharmacol. 2006, 69, 691-696. (Pubitemid 43363843)
-
(2006)
Molecular Pharmacology
, vol.69
, Issue.3
, pp. 691-696
-
-
Sun, H.K.1
Seok, J.W.2
Xiao, O.M.3
Jin, K.4
Greenberg, D.A.5
-
154
-
-
19444373244
-
Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores
-
DOI 10.1016/j.neuropharm.2005.01.005, PII S0028390805000316
-
Zhuang, S. Y.; Bridges, D.; Grigorenko, E.; McCloud, S.; Boon, A.; Hampson, R. E.; Deadwyler, S. A. Cannabinoids produce neuroprotection by reducing intracellular calcium release from ryanodine-sensitive stores. Neuropharmacology 2005, 48, 1086-1096. (Pubitemid 40725981)
-
(2005)
Neuropharmacology
, vol.48
, Issue.8 SPEC. ISS.
, pp. 1086-1096
-
-
Zhuang, S.-Y.1
Bridges, D.2
Grigorenko, E.3
McCloud, S.4
Boon, A.5
Hampson, R.E.6
Deadwyler, S.A.7
-
155
-
-
0036023927
-
The impact of ocular blood flow in glaucoma
-
Flammer, J.; Orgul, S.; Costa, V. P.; Orzalesi, N.; Krieglstein, G. K.; Serra, L. M.; Renard, J. P.; Stefansson, E. The impact of ocular blood flow in glaucoma. Prog. Retin. Eye Res. 2002, 21, 359-393.
-
(2002)
Prog. Retin. Eye Res.
, vol.21
, pp. 359-393
-
-
Flammer, J.1
Orgul, S.2
Costa, V.P.3
Orzalesi, N.4
Krieglstein, G.K.5
Serra, L.M.6
Renard, J.P.7
Stefansson, E.8
-
156
-
-
77950354281
-
Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension
-
Galanopoulos, A.; Goldberg, I. Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension. Clin. Ophthalmol. 2009, 3, 117-122.
-
(2009)
Clin. Ophthalmol.
, vol.3
, pp. 117-122
-
-
Galanopoulos, A.1
Goldberg, I.2
-
157
-
-
0035198185
-
Alpha(2) -Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia
-
Donello, J. E.; Padillo, E. U.; Webster, M. L.; Wheeler, L. A.; Gil, D. W. alpha (2) -Adrenoceptor agonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischemia. J. Pharmacol. Exp. Ther. 2001, 296, 216-223.
-
(2001)
J. Pharmacol. Exp. Ther.
, vol.296
, pp. 216-223
-
-
Donello, J.E.1
Padillo, E.U.2
Webster, M.L.3
Wheeler, L.A.4
Gil, D.W.5
-
158
-
-
0036322780
-
Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina
-
Baptiste, D. C.; Hartwick, A. T.; Jollimore, C. A.; Baldridge, W. H.; Chauhan, B. C.; Tremblay, F.; Kelly, M. E. Comparison of the neuroprotective effects of adrenoceptor drugs in retinal cell culture and intact retina. Invest. Ophthalmol. Vis. Sci. 2002, 43, 2666-2676.
-
(2002)
Invest. Ophthalmol. Vis. Sci.
, vol.43
, pp. 2666-2676
-
-
Baptiste, D.C.1
Hartwick, A.T.2
Jollimore, C.A.3
Baldridge, W.H.4
Chauhan, B.C.5
Tremblay, F.6
Kelly, M.E.7
-
159
-
-
0037182095
-
Synaptic distribution of ionotropic glutamate receptors in the inner plexiform layer of the primate retina
-
DOI 10.1002/cne.10220
-
Grunert, U.; Haverkamp, S.; Fletcher, E. L.; Wassle, H. Synaptic distribution of ionotropic glutamate receptors in the inner plexiform layer of the primate retina. J. Comp. Neurol. 2002, 447, 138-151. (Pubitemid 34457375)
-
(2002)
Journal of Comparative Neurology
, vol.447
, Issue.2
, pp. 138-151
-
-
Grunert, U.1
Haverkamp, S.2
Fletcher, E.L.3
Wassle, H.4
-
160
-
-
0043194100
-
Inner retinal neurons display differential responses to N-methyl-D-aspartate receptor activation
-
DOI 10.1002/cne.10830
-
Sun, D.; Rait, J. L.; Kalloniatis, M. Inner retinal neurons display differential responses to Nmethyl-D-aspartate receptor activation. J. Comp. Neurol. 2003, 465, 38-56. (Pubitemid 37075679)
-
(2003)
Journal of Comparative Neurology
, vol.465
, Issue.1
, pp. 38-56
-
-
Sun, D.1
Rait, J.L.2
Kalloniatis, M.3
-
161
-
-
0029915446
-
Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma
-
Dreyer, E. B.; Zurakowski, D.; Schumer, R. A.; Podos, S. M.; Lipton, S. A. Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch. Ophthalmol. 1996, 114, 299-305.
-
(1996)
Arch. Ophthalmol.
, vol.114
, pp. 299-305
-
-
Dreyer, E.B.1
Zurakowski, D.2
Schumer, R.A.3
Podos, S.M.4
Lipton, S.A.5
-
162
-
-
0026636199
-
Glutamate release in experimental ischaemia of the retina: An approach using microdialysis
-
Louzada-Junior, P.; Dias, J. J.; Santos, W. F.; Lachat, J. J.; Bradford, H. F.; Coutinho-Netto, J. Glutamate release in experimental ischaemia of the retina: An approach using microdialysis. J. Neurochem. 1992, 59, 358-363.
-
(1992)
J. Neurochem.
, vol.59
, pp. 358-363
-
-
Louzada-Junior, P.1
Dias, J.J.2
Santos, W.F.3
Lachat, J.J.4
Bradford, H.F.5
Coutinho-Netto, J.6
-
163
-
-
0027972715
-
Effects of ischaemia on neurotransmitter release from the isolated retina
-
Neal, M. J.; Cunningham, J. R.; Hutson, P. H.; Hogg, J. Effects of ischaemia on neurotransmitter release from the isolated retina. J. Neurochem. 1994, 62, 1025-1033.
-
(1994)
J. Neurochem.
, vol.62
, pp. 1025-1033
-
-
Neal, M.J.1
Cunningham, J.R.2
Hutson, P.H.3
Hogg, J.4
-
164
-
-
0029796092
-
Disturbances in the distribution of neurotransmitters in the rat retina after ischemia
-
Perlman, J. I.; McCole, S. M.; Pulluru, P.; Chang, C. J.; Lam, T. T.; Tso, M. O. Disturbances in the distribution of neurotransmitters in the rat retina after ischemia. Curr. Eye Res. 1996, 15, 589-596.
-
(1996)
Curr. Eye Res.
, vol.15
, pp. 589-596
-
-
Perlman, J.I.1
McCole, S.M.2
Pulluru, P.3
Chang, C.J.4
Lam, T.T.5
Tso, M.O.6
-
165
-
-
34250626907
-
Low dose ketamine: A therapeutic and research tool to explore N-methyl-Daspartate (NMDA) receptor-mediated plasticity in pain pathways
-
Chizh, B. A. Low dose ketamine: A therapeutic and research tool to explore N-methyl-Daspartate (NMDA) receptor-mediated plasticity in pain pathways. J. Psychopharmacol. 2007, 21, 259-271.
-
(2007)
J. Psychopharmacol.
, vol.21
, pp. 259-271
-
-
Chizh, B.A.1
-
166
-
-
34247635705
-
The NMDA receptor as a therapeutic target in major depressive disorder
-
Pittenger, C.; Sanacora, G.; Krystal, J. H. The NMDA receptor as a therapeutic target in major depressive disorder. CNS Neurol. Disord. Drug Targets 2007, 6, 101-115.
-
(2007)
CNS Neurol. Disord. Drug Targets
, vol.6
, pp. 101-115
-
-
Pittenger, C.1
Sanacora, G.2
Krystal, J.H.3
-
167
-
-
0034766994
-
Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey
-
discussion S285-S286
-
Hare, W.; WoldeMussie, E.; Lai, R.; Ton, H.; Ruiz, G.; Feldmann, B.; Wijono, M.; Chun, T.; Wheeler, L. Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey. Surv. Ophthalmol. 2001, 45 (Suppl. 3), S284-S289; discussion S285-S286.
-
(2001)
Surv. Ophthalmol.
, vol.45
, Issue.3 SUPPL.
-
-
Hare, W.1
WoldeMussie, E.2
Lai, R.3
Ton, H.4
Ruiz, G.5
Feldmann, B.6
Wijono, M.7
Chun, T.8
Wheeler, L.9
-
168
-
-
0345072185
-
Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia
-
Lagreze, W. A.; Knorle, R.; Bach, M.; Feuerstein, T. J. Memantine is neuroprotective in a rat model of pressure-induced retinal ischemia. Invest. Ophthalmol. Vis. Sci. 1998, 39, 1063-1066.
-
(1998)
Invest. Ophthalmol. Vis. Sci.
, vol.39
, pp. 1063-1066
-
-
Lagreze, W.A.1
Knorle, R.2
Bach, M.3
Feuerstein, T.J.4
-
169
-
-
0033038186
-
Memantine reduces alterations to the mammalian retina, in situ, induced by ischemia
-
Osborne, N. N. Memantine reduces alterations to the mammalian retina, in situ, induced by ischemia. Vis. Neurosci. 1999, 16, 45-52.
-
(1999)
Vis. Neurosci.
, vol.16
, pp. 45-52
-
-
Osborne, N.N.1
-
170
-
-
0036913245
-
Neuroprotective effect of memantine in different retinal injury models in rats
-
WoldeMussie, E.; Yoles, E.; Schwartz, M.; Ruiz, G.; Wheeler, L. A. Neuroprotective effect of memantine in different retinal injury models in rats. J. Glaucoma 2002, 11, 474-480.
-
(2002)
J. Glaucoma
, vol.11
, pp. 474-480
-
-
WoldeMussie, E.1
Yoles, E.2
Schwartz, M.3
Ruiz, G.4
Wheeler, L.A.5
-
171
-
-
3242879784
-
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures
-
DOI 10.1167/iovs.03-0566
-
Hare, W. A.; WoldeMussie, E.; Lai, R. K.; Ton, H.; Ruiz, G.; Chun, T.; Wheeler, L. Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, I: Functional measures. Invest. Ophthalmol. Vis. Sci. 2004, 45, 2625-2639. (Pubitemid 38998859)
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, Issue.8
, pp. 2625-2639
-
-
Hare, W.A.1
WoldeMussie, E.2
Lai, R.K.3
Ton, H.4
Ruiz, G.5
Chun, T.6
Wheeler, L.7
-
172
-
-
3242892118
-
Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures
-
DOI 10.1167/iovs.03-0567
-
Hare, W. A.; WoldeMussie, E.; Weinreb, R. N.; Ton, H.; Ruiz, G.; Wijono, M.; Feldmann, B.; Zangwill, L.; Wheeler, L. Efficacy and safety of memantine treatment for reduction of changes associated with experimental glaucoma in monkey, II: Structural measures. Invest. Ophthalmol. Vis. Sci. 2004, 45, 2640-2651. (Pubitemid 38998860)
-
(2004)
Investigative Ophthalmology and Visual Science
, vol.45
, Issue.8
, pp. 2640-2651
-
-
Hare, W.A.1
WoldeMussie, E.2
Weinreb, R.N.3
Ton, H.4
Ruiz, G.5
Wijono, M.6
Feldmann, B.7
Zangwill, L.8
Wheeler, L.9
-
173
-
-
0034754201
-
Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension
-
WoldeMussie, E.; Ruiz, G.; Wijono, M.; Wheeler, L. A. Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension. Invest. Ophthalmol. Vis. Sci. 2001, 42, 2849-2855.
-
(2001)
Invest. Ophthalmol. Vis. Sci.
, vol.42
, pp. 2849-2855
-
-
WoldeMussie, E.1
Ruiz, G.2
Wijono, M.3
Wheeler, L.A.4
-
174
-
-
20344407819
-
Human ganglion cells express the alpha-2 adrenergic receptor: Relevance to neuroprotection
-
Kalapesi, F. B.; Coroneo, M. T.; Hill, M. A. Human ganglion cells express the alpha-2 adrenergic receptor: Relevance to neuroprotection. Br. J. Ophthalmol. 2005, 89, 758-763.
-
(2005)
Br. J. Ophthalmol.
, vol.89
, pp. 758-763
-
-
Kalapesi, F.B.1
Coroneo, M.T.2
Hill, M.A.3
-
175
-
-
37749033221
-
Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension
-
Katz, L. J.; Simmons, S. T.; Craven, E. R. Efficacy and safety of brimonidine and dorzolamide for intraocular pressure lowering in glaucoma and ocular hypertension. Curr. Med. Res. Opin. 2007, 23, 2971-2983.
-
(2007)
Curr. Med. Res. Opin.
, vol.23
, pp. 2971-2983
-
-
Katz, L.J.1
Simmons, S.T.2
Craven, E.R.3
-
176
-
-
34047247369
-
Alpha2 adrenergic receptor-mediated modulation of cytosolic Ca++ signals at the inner plexiform layer of the rat retina
-
Dong, C. J.; Guo, Y.; Wheeler, L.; Hare, W. A. Alpha2 adrenergic receptor-mediated modulation of cytosolic Ca++ signals at the inner plexiform layer of the rat retina. Invest. Ophthalmol. Vis. Sci. 2007, 48, 1410-1415.
-
(2007)
Invest. Ophthalmol. Vis. Sci.
, vol.48
, pp. 1410-1415
-
-
Dong, C.J.1
Guo, Y.2
Wheeler, L.3
Hare, W.A.4
-
177
-
-
0029895790
-
Genetic evidence for involvement of multiple effector systems in alpha 2A-adrenergic receptor inhibition of stimulus-secretion coupling
-
Lakhlani, P. P.; Lovinger, D. M.; Limbird, L. E. Genetic evidence for involvement of multiple effector systems in alpha 2A-adrenergic receptor inhibition of stimulus-secretion coupling. Mol. Pharmacol. 1996, 50, 96-103.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 96-103
-
-
Lakhlani, P.P.1
Lovinger, D.M.2
Limbird, L.E.3
-
178
-
-
53449088505
-
Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity
-
Dong, C. J.; Guo, Y.; Agey, P.; Wheeler, L.; Hare, W. A. Alpha2 adrenergic modulation of NMDA receptor function as a major mechanism of RGC protection in experimental glaucoma and retinal excitotoxicity. Invest. Ophthalmol. Vis. Sci. 2008, 49, 4515-4522.
-
(2008)
Invest. Ophthalmol. Vis. Sci.
, vol.49
, pp. 4515-4522
-
-
Dong, C.J.1
Guo, Y.2
Agey, P.3
Wheeler, L.4
Hare, W.A.5
-
180
-
-
34548543758
-
Presenilinmediated signal transduction
-
Cowburn, R. F.; Popescu, B. O.; Ankarcrona, M.; Dehvari, N.; Cedazo-Minguez, A. Presenilinmediated signal transduction. Physiol. Behav. 2007, 92, 93-97.
-
(2007)
Physiol. Behav.
, vol.92
, pp. 93-97
-
-
Cowburn, R.F.1
Popescu, B.O.2
Ankarcrona, M.3
Dehvari, N.4
Cedazo-Minguez, A.5
-
181
-
-
0031017795
-
Light and electron microscopic localization of presenilin-1 in primate brain
-
Lah, J. J.; Heilman, C. J.; Nash, N. R.; Rees, H. D.; Yi, H.; Counts, S. E.; Levey, A. I. Light and electron microscopic localization of presenilin-1 in primate brain. J. Neurosci. 1997, 17, 1971-1980. (Pubitemid 27106756)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.6
, pp. 1971-1980
-
-
Lah, J.J.1
Heilman, C.J.2
Nash, N.R.3
Rees, H.D.4
Yi, H.5
Counts, S.E.6
Levey, A.I.7
-
182
-
-
10544229795
-
Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues
-
Lee, M. K.; Slunt, H. H.; Martin, L. J.; Thinakaran, G.; Kim, G.; Gandy, S. E.; Seeger, M.; Koo, E.; Price, D. L.; Sisodia, S. S. Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. J. Neurosci. 1996, 16, 7513-7525. (Pubitemid 26389690)
-
(1996)
Journal of Neuroscience
, vol.16
, Issue.23
, pp. 7513-7525
-
-
Lee, M.K.1
Slunt, H.H.2
Martin, L.J.3
Thinakaran, G.4
Kim, G.5
Gandy, S.E.6
Seeger, M.7
Koo, E.8
Price, D.L.9
Sisodia, S.S.10
-
183
-
-
15444350008
-
Presenilin-1 protein expression in familial and sporadic Alzheimer's disease
-
DOI 10.1002/ana.410410610
-
Levey, A. I.; Heilman, C. J.; Lah, J. J.; Nash, N. R.; Rees, H. D.; Wakai, M.; Mirra, S. S.; Rye, D. B.; Nochlin, D.; Bird, T. D.; Mufson, E. J. Presenilin-1 protein expression in familial and sporadic Alzheimer's disease. Ann. Neurol. 1997, 41, 742-753. (Pubitemid 27249179)
-
(1997)
Annals of Neurology
, vol.41
, Issue.6
, pp. 742-753
-
-
Levey, A.I.1
Heilman, C.J.2
Lah, J.J.3
Nash, N.R.4
Rees, H.D.5
Wakai, M.6
Mirra, S.S.7
Rye, D.B.8
Nochlin, D.9
Bird, T.D.10
Mufson, E.J.11
-
184
-
-
3342889548
-
Presenilin 1 is essential for cardiac morphogenesis
-
DOI 10.1002/dvdy.20098
-
Nakajima, M.; Moriizumi, E.; Koseki, H.; Shirasawa, T. Presenilin 1 is essential for cardiac morphogenesis. Dev. Dyn. 2004, 230, 795-799. (Pubitemid 38993879)
-
(2004)
Developmental Dynamics
, vol.230
, Issue.4
, pp. 795-799
-
-
Nakajima, M.1
Moriizumi, E.2
Koseki, H.3
Shirasawa, T.4
-
185
-
-
0030779784
-
Skeletal and CNS defects in Presenilin-1-deficient mice
-
Shen, J.; Bronson, R. T.; Chen, D. F.; Xia, W.; Selkoe, D. J.; Tonegawa, S. Skeletal and CNS defects in Presenilin-1-deficient mice. Cell 1997, 89, 629-639. (Pubitemid 27511773)
-
(1997)
Cell
, vol.89
, Issue.4
, pp. 629-639
-
-
Shen, J.1
Bronson, R.T.2
Chen, D.F.3
Xia, W.4
Selkoe, D.J.5
Tonegawa, S.6
-
186
-
-
0032728957
-
Mice lacking both presenilin genes exhibit early embryonic patterning defects
-
Donoviel, D. B.; Hadjantonakis, A. K.; Ikeda, M.; Zheng, H.; Hyslop, P. S.; Bernstein, A. Mice lacking both presenilin genes exhibit early embryonic patterning defects. Genes. Dev. 1999, 13, 2801-2810.
-
(1999)
Genes. Dev.
, vol.13
, pp. 2801-2810
-
-
Donoviel, D.B.1
Hadjantonakis, A.K.2
Ikeda, M.3
Zheng, H.4
Hyslop, P.S.5
Bernstein, A.6
-
187
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin I variants elevate aβ1- 42/1-40 ratio in vitro and in vivo
-
DOI 10.1016/S0896-6273(00)80230-5
-
Borchelt, D. R.; Thinakaran, G.; Eckman, C. B.; Lee, M. K.; Davenport, F.; Ratovitsky, T.; Prada, C. M.; Kim, G.; Seekins, S.; Yager, D.; Slunt, H. H.; Wang, R.; Seeger, M.; Levey, A. I.; Gandy, S. E.; Copeland, N. G.; Jenkins, N. A.; Price, D. L.; Younkin, S. G.; Sisodia, S. S. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo. Neuron 1996, 17, 1005-1013. (Pubitemid 26424026)
-
(1996)
Neuron
, vol.17
, Issue.5
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.-M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
188
-
-
0037183702
-
The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations
-
Cedazo-Minguez, A.; Popescu, B. O.; Ankarcrona, M.; Nishimura, T.; Cowburn, R. F. The presenilin 1 deltaE9 mutation gives enhanced basal phospholipase C activity and a resultant increase in intracellular calcium concentrations. J. Biol. Chem. 2002, 277, 36646-36655.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36646-36655
-
-
Cedazo-Minguez, A.1
Popescu, B.O.2
Ankarcrona, M.3
Nishimura, T.4
Cowburn, R.F.5
-
189
-
-
14244268498
-
Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage
-
Chyung, J. H.; Raper, D. M.; Selkoe, D. J. Gamma-secretase exists on the plasma membrane as an intact complex that accepts substrates and effects intramembrane cleavage. J. Biol. Chem. 2005, 280, 4383-4392.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 4383-4392
-
-
Chyung, J.H.1
Raper, D.M.2
Selkoe, D.J.3
-
190
-
-
0030811016
-
Hyperaccumulation of FAD-linked presenilin 1 variants in vivo
-
DOI 10.1038/nm0797-756
-
Lee, M. K.; Borchelt, D. R.; Kim, G.; Thinakaran, G.; Slunt, H. H.; Ratovitski, T.; Martin, L. J.; Kittur, A.; Gandy, S.; Levey, A. I.; Jenkins, N.; Copeland, N.; Price, D. L.; Sisodia, S. S. Hyperaccumulation of FAD-linked presenilin 1 variants in vivo. Nat. Med. 1997, 3, 756-760. (Pubitemid 27298719)
-
(1997)
Nature Medicine
, vol.3
, Issue.7
, pp. 756-760
-
-
Lee, M.K.1
Borchelt, D.R.2
Kim, G.3
Thinakaran, G.4
Slunt, H.H.5
Ratovitski, T.6
Martin, L.J.7
Kittur, A.8
Gandy, S.9
Levey, A.I.10
Jenkins, N.11
Copeland, N.12
Price, D.L.13
Sisodia, S.S.14
-
191
-
-
47749095383
-
Linking calcium to Abeta and Alzheimer's disease
-
Green, K. N.; LaFerla, F. M. Linking calcium to Abeta and Alzheimer's disease. Neuron 2008, 59, 190-194.
-
(2008)
Neuron
, vol.59
, pp. 190-194
-
-
Green, K.N.1
LaFerla, F.M.2
-
192
-
-
27444441308
-
A nine-transmembrane domain topology for presenilin 1
-
DOI 10.1074/jbc.M507217200
-
Laudon, H.; Hansson, E. M.; Melen, K.; Bergman, A.; Farmery, M. R.; Winblad, B.; Lendahl, U.; von Heijne, G.; Naslund, J. A nine-transmembrane domain topology for presenilin 1. J. Biol. Chem. 2005, 280, 35352-35360. (Pubitemid 41532724)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.42
, pp. 35352-35360
-
-
Laudon, H.1
Hansson, E.M.2
Melen, K.3
Bergman, A.4
Farmery, M.R.5
Winblad, B.6
Lendahl, U.7
Von Heijne, G.8
Naslund, J.9
-
193
-
-
15844425969
-
Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo
-
DOI 10.1016/S0896-6273(00)80291-3
-
Thinakaran, G.; Borchelt, D. R.; Lee, M. K.; Slunt, H. H.; Spitzer, L.; Kim, G.; Ratovitsky, T.; Davenport, F.; Nordstedt, C.; Seeger, M.; Hardy, J.; Levey, A. I.; Gandy, S. E.; Jenkins, N. A.; Copeland, N. G.; Price, D. L.; Sisodia, S. S. Endoproteolysis of presenilin 1 and accumulation of processed derivatives in vivo. Neuron 1996, 17, 181-190. (Pubitemid 26251602)
-
(1996)
Neuron
, vol.17
, Issue.1
, pp. 181-190
-
-
Thinakaran, G.1
Borchelt, D.R.2
Lee, M.K.3
Slunt, H.H.4
Spitzer, L.5
Kim, G.6
Ratovitsky, T.7
Davenport, F.8
Nordstedt, C.9
Seeger, M.10
Hardy, J.11
Levey, A.I.12
Gandy, S.E.13
Jenkins, N.A.14
Copeland, N.G.15
Price, D.L.16
Sisodia, S.S.17
-
194
-
-
33748746861
-
Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway
-
Spasic, D.; Tolia, A.; Dillen, K.; Baert, V.; De Strooper, B.; Vrijens, S.; Annaert, W. Presenilin-1 maintains a nine-transmembrane topology throughout the secretory pathway. J. Biol. Chem. 2006, 281, 26569-26577.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 26569-26577
-
-
Spasic, D.1
Tolia, A.2
Dillen, K.3
Baert, V.4
De Strooper, B.5
Vrijens, S.6
Annaert, W.7
-
195
-
-
0032488995
-
The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex
-
Capell, A.; Grunberg, J.; Pesold, B.; Diehlmann, A.; Citron, M.; Nixon, R.; Beyreuther, K.; Selkoe, D. J.; Haass, C. The proteolytic fragments of the Alzheimer's disease-associated presenilin-1 form heterodimers and occur as a 100-150-kDa molecular mass complex. J. Biol. Chem. 1998, 273, 3205-3211.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 3205-3211
-
-
Capell, A.1
Grunberg, J.2
Pesold, B.3
Diehlmann, A.4
Citron, M.5
Nixon, R.6
Beyreuther, K.7
Selkoe, D.J.8
Haass, C.9
-
196
-
-
0141957935
-
Alzheimer's disease proteins in cerebellar and hippocampal synapses during postnatal development and aging of the rat
-
Ribaut-Barassin, C.; Dupont, J. L.; Haeberle, A. M.; Bombarde, G.; Huber, G.; Moussaoui, S.; Mariani, J.; Bailly, Y. Alzheimer's disease proteins in cerebellar and hippocampal synapses during postnatal development and aging of the rat. Neuroscience 2003, 120, 405-423.
-
(2003)
Neuroscience
, vol.120
, pp. 405-423
-
-
Ribaut-Barassin, C.1
Dupont, J.L.2
Haeberle, A.M.3
Bombarde, G.4
Huber, G.5
Moussaoui, S.6
Mariani, J.7
Bailly, Y.8
-
197
-
-
0034657414
-
Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice
-
Leissring, M. A.; Akbari, Y.; Fanger, C. M.; Cahalan, M. D.; Mattson, M. P.; LaFerla, F. M. Capacitative calcium entry deficits and elevated luminal calcium content in mutant presenilin-1 knockin mice. J. Cell. Biol. 2000, 149, 793-798.
-
(2000)
J. Cell. Biol.
, vol.149
, pp. 793-798
-
-
Leissring, M.A.1
Akbari, Y.2
Fanger, C.M.3
Cahalan, M.D.4
Mattson, M.P.5
LaFerla, F.M.6
-
198
-
-
0034979346
-
Subcellular mechanisms of presenilinmediated enhancement of calcium signaling
-
Leissring, M. A.; LaFerla, F. M.; Callamaras, N.; Parker, I. Subcellular mechanisms of presenilinmediated enhancement of calcium signaling. Neurobiol. Dis. 2001, 8, 469-478.
-
(2001)
Neurobiol. Dis.
, vol.8
, pp. 469-478
-
-
Leissring, M.A.1
LaFerla, F.M.2
Callamaras, N.3
Parker, I.4
-
199
-
-
0034682541
-
Calsenilin reverses presenilin-mediated enhancement of calcium signaling
-
Leissring, M. A.; Yamasaki, T. R.; Wasco, W.; Buxbaum, J. D.; Parker, I.; LaFerla, F. M. Calsenilin reverses presenilin-mediated enhancement of calcium signaling. Proc. Natl. Acad. Sci. USA 2000, 97, 8590-8593.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8590-8593
-
-
Leissring, M.A.1
Yamasaki, T.R.2
Wasco, W.3
Buxbaum, J.D.4
Parker, I.5
LaFerla, F.M.6
-
200
-
-
0034652369
-
Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis
-
Mattson, M. P.; Zhu, H.; Yu, J.; Kindy, M. S. Presenilin-1 mutation increases neuronal vulnerability to focal ischemia in vivo and to hypoxia and glucose deprivation in cell culture: Involvement of perturbed calcium homeostasis. J. Neurosci. 2000, 20, 1358-1364.
-
(2000)
J. Neurosci.
, vol.20
, pp. 1358-1364
-
-
Mattson, M.P.1
Zhu, H.2
Yu, J.3
Kindy, M.S.4
-
201
-
-
34248185927
-
2+ leak function of presenilin 1
-
2+ leak function of presenilin 1. J. Clin. Invest. 2007, 117, 1230-1239.
-
(2007)
J. Clin. Invest.
, vol.117
, pp. 1230-1239
-
-
Nelson, O.1
Tu, H.2
Lei, T.3
Bentahir, M.4
De Strooper, B.5
Bezprozvanny, I.6
-
202
-
-
24644456470
-
Calcium dysregulation in Alzheimer's disease: Recent advances gained from genetically modified animals
-
Smith, I. F.; Green, K. N.; LaFerla, F. M. Calcium dysregulation in Alzheimer's disease: Recent advances gained from genetically modified animals. Cell Calcium 2005, 38, 427-437.
-
(2005)
Cell. Calcium.
, vol.38
, pp. 427-437
-
-
Smith, I.F.1
Green, K.N.2
LaFerla, F.M.3
-
203
-
-
28744456107
-
2+ signaling
-
DOI 10.1096/fj.05-3744fje
-
2+ signaling. FASEB J. 2005, 19, 2069-2071. (Pubitemid 41759768)
-
(2005)
FASEB Journal
, vol.19
, Issue.14
, pp. 2069-2071
-
-
Takeda, T.1
Asahi, M.2
Yamaguchi, O.3
Hikoso, S.4
Nakayama, H.5
Kusakari, Y.6
Kawai, M.7
Hongo, K.8
Higuchi, Y.9
Kashiwase, K.10
Watanabe, T.11
Taniike, M.12
Nakai, A.13
Nishida, K.14
Kurihara, S.15
Donoviel, D.B.16
Bernstein, A.17
Tomita, T.18
Iwatsubo, T.19
Hori, M.20
Otsu, K.21
more..
-
204
-
-
33646377385
-
Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels
-
Zatti, G.; Burgo, A.; Giacomello, M.; Barbiero, L.; Ghidoni, R.; Sinigaglia, G.; Florean, C.; Bagnoli, S.; Binetti, G.; Sorbi, S.; Pizzo, P.; Fasolato, C. Presenilin mutations linked to familial Alzheimer's disease reduce endoplasmic reticulum and Golgi apparatus calcium levels. Cell Calcium 2006, 39, 539-550.
-
(2006)
Cell. Calcium.
, vol.39
, pp. 539-550
-
-
Zatti, G.1
Burgo, A.2
Giacomello, M.3
Barbiero, L.4
Ghidoni, R.5
Sinigaglia, G.6
Florean, C.7
Bagnoli, S.8
Binetti, G.9
Sorbi, S.10
Pizzo, P.11
Fasolato, C.12
-
205
-
-
1542300766
-
2+ release from intracellular stores
-
DOI 10.1016/j.nbd.2003.11.002, PII S0969996103002390
-
2+ release from intracellular stores. Neurobiol. Dis. 2004, 15, 269-278. (Pubitemid 38296758)
-
(2004)
Neurobiology of Disease
, vol.15
, Issue.2
, pp. 269-278
-
-
Zatti, G.1
Ghidoni, R.2
Barbiero, L.3
Binetti, G.4
Pozzan, T.5
Fasolato, C.6
Pizzo, P.7
-
206
-
-
33744925947
-
Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models
-
DOI 10.1016/j.neurobiolaging.2005.04.014, PII S019745800500196X
-
Reddy, P. H.; McWeeney, S. Mapping cellular transcriptosomes in autopsied Alzheimer's disease subjects and relevant animal models. Neurobiol. Aging 2006, 27, 1060-1077. (Pubitemid 43850649)
-
(2006)
Neurobiology of Aging
, vol.27
, Issue.8
, pp. 1060-1077
-
-
Reddy, P.H.1
McWeeney, S.2
-
207
-
-
0023369739
-
Hypothesis on the regulation of cytosol calcium concentration and the aging brain
-
Khachaturian, Z. S. Hypothesis on the regulation of cytosol calcium concentration and the aging brain. Neurobiol. Aging 1987, 8, 345-346.
-
(1987)
Neurobiol. Aging
, vol.8
, pp. 345-346
-
-
Khachaturian, Z.S.1
-
208
-
-
3943092621
-
Pathways towards and away from Alzheimer's disease
-
Mattson, M. P. Pathways towards and away from Alzheimer's disease. Nature 2004, 430, 631-639.
-
(2004)
Nature
, vol.430
, pp. 631-639
-
-
Mattson, M.P.1
-
209
-
-
33845217332
-
Mutations of presenilin genes in dilated cardiomyopathy and heart failure
-
Li, D.; Parks, S. B.; Kushner, J. D.; Nauman, D.; Burgess, D.; Ludwigsen, S.; Partain, J.; Nixon, R. R.; Allen, C. N.; Irwin, R. P.; Jakobs, P. M.; Litt, M.; Hershberger, R. E. Mutations of presenilin genes in dilated cardiomyopathy and heart failure. Am. J. Hum. Genet. 2006, 79, 1030-1039.
-
(2006)
Am. J. Hum. Genet.
, vol.79
, pp. 1030-1039
-
-
Li, D.1
Parks, S.B.2
Kushner, J.D.3
Nauman, D.4
Burgess, D.5
Ludwigsen, S.6
Partain, J.7
Nixon, R.R.8
Allen, C.N.9
Irwin, R.P.10
Jakobs, P.M.11
Litt, M.12
Hershberger, R.E.13
-
210
-
-
0026624769
-
Changes in intracellular free calcium concentration during long exposures to simulated ischemia in isolated mammalian ventricular muscle
-
Lee, J. A.; Allen, D. G. Changes in intracellular free calcium concentration during long exposures to simulated ischemia in isolated mammalian ventricular muscle. Circ. Res. 1992, 71, 58-69.
-
(1992)
Circ. Res.
, vol.71
, pp. 58-69
-
-
Lee, J.A.1
Allen, D.G.2
-
211
-
-
42049108814
-
Mechanisms underlying acute protection from cardiac ischemiareperfusion injury
-
Murphy, E.; Steenbergen, C. Mechanisms underlying acute protection from cardiac ischemiareperfusion injury. Physiol. Rev. 2008, 88, 581-609.
-
(2008)
Physiol. Rev.
, vol.88
, pp. 581-609
-
-
Murphy, E.1
Steenbergen, C.2
-
212
-
-
33846506801
-
Inflammation, Proinflammatory Mediators and Myocardial Ischemia-reperfusion Injury
-
DOI 10.1016/j.hoc.2006.11.010, PII S0889858806001948, Inflamation, Hemostasis, and Blood Conservation Strategies
-
Vinten-Johansen, J.; Jiang, R.; Reeves, J. G.; Mykytenko, J.; Deneve, J.; Jobe, L. J. Inflammation, proinflammatory mediators and myocardial ischemia-reperfusion Injury. Hematol. Oncol. Clin. North Am. 2007, 21, 123-145. (Pubitemid 46156986)
-
(2007)
Hematology/Oncology Clinics of North America
, vol.21
, Issue.1
, pp. 123-145
-
-
Vinten-Johansen, J.1
Jiang, R.2
Reeves, J.G.3
Mykytenko, J.4
Deneve, J.5
Jobe, L.J.6
-
213
-
-
0037207059
-
Presenilins in the heart: Presenilin-2 expression is increased by low glucose and by hypoxia in cardiac cells
-
DOI 10.1016/S0167-0115(02)00225-2, PII S0167011502002252
-
Mohuczy, D.; Qian, K.; Phillips, M. I. Presenilins in the heart: Presenilin-2 expression is increased by low glucose and by hypoxia in cardiac cells. Regul. Pept. 2002, 110, 1-7. (Pubitemid 35439144)
-
(2002)
Regulatory Peptides
, vol.110
, Issue.1
, pp. 1-7
-
-
Mohuczy, D.1
Qian, K.2
Phillips, M.I.3
-
214
-
-
33748140720
-
2+ Leak Channels, a Function Disrupted by Familial Alzheimer's Disease-Linked Mutations
-
DOI 10.1016/j.cell.2006.06.059, PII S0092867406010257
-
2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations. Cell 2006, 126, 981-993. (Pubitemid 44310781)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 981-993
-
-
Tu, H.1
Nelson, O.2
Bezprozvanny, A.3
Wang, Z.4
Lee, S.-F.5
Hao, Y.-H.6
Serneels, L.7
De Strooper, B.8
Yu, G.9
Bezprozvanny, I.10
-
215
-
-
0034640292
-
Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor
-
DOI 10.1074/jbc.M909882199
-
Pack-Chung, E.; Meyers, M. B.; Pettingell, W. P.; Moir, R. D.; Brownawell, A. M.; Cheng, I.; Tanzi, R. E.; Kim, T. W. Presenilin 2 interacts with sorcin, a modulator of the ryanodine receptor. J. Biol. Chem. 2000, 275, 14440-14445. (Pubitemid 30339730)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.19
, pp. 14440-14445
-
-
Pack-Chung, E.1
Meyers, M.B.2
Pettingell, W.P.3
Moir, R.D.4
Brownawell, A.M.5
Cheng, I.6
Tanzi, R.E.7
Kim, T.-W.8
-
216
-
-
0028840294
-
Association of sorcin with the cardiac ryanodine receptor
-
Meyers, M. B.; Pickel, V. M.; Sheu, S. S.; Sharma, V. K.; Scotto, K. W.; Fishman, G. I. Association of sorcin with the cardiac ryanodine receptor. J. Biol. Chem. 1995, 270, 26411-26418.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 26411-26418
-
-
Meyers, M.B.1
Pickel, V.M.2
Sheu, S.S.3
Sharma, V.K.4
Scotto, K.W.5
Fishman, G.I.6
-
218
-
-
59349110743
-
Photoactivatable mCherry for high-resolution two-color fluorescence microscopy
-
Subach, F. V.; Patterson, G. H.; Manley, S.; Gillette, J. M.; Lippincott-Schwartz, J.; Verkhusha, V. V. Photoactivatable mCherry for high-resolution two-color fluorescence microscopy. Nat. Meth. 2009, 6, 153-159.
-
(2009)
Nat. Meth.
, vol.6
, pp. 153-159
-
-
Subach, F.V.1
Patterson, G.H.2
Manley, S.3
Gillette, J.M.4
Lippincott-Schwartz, J.5
Verkhusha, V.V.6
-
219
-
-
68949190920
-
Ratiometric Ca+2 measurement in human recombinant muscarinic receptor subtypes using the Flexstation scanning fluorometer
-
Gupta, S.; Singh, R. K.; Nanda, K.; Chatterjee, M.; Tiwari, A.; Sundaram, S.; Gupta, D.; Chugh, A.; Dastidar, S.; Ray, A. Ratiometric Ca+2 measurement in human recombinant muscarinic receptor subtypes using the Flexstation scanning fluorometer. J. Recept. Signal. Transduct. Res. 2009, 29, 100-106.
-
(2009)
J. Recept. Signal. Transduct. Res.
, vol.29
, pp. 100-106
-
-
Gupta, S.1
Singh, R.K.2
Nanda, K.3
Chatterjee, M.4
Tiwari, A.5
Sundaram, S.6
Gupta, D.7
Chugh, A.8
Dastidar, S.9
Ray, A.10
-
220
-
-
67349274521
-
2+ indicator-caused fluorescence artifact
-
2+ indicator-caused fluorescence artifact. Anal. Biochem. 2009, 390, 212-214.
-
(2009)
Anal. Biochem.
, vol.390
, pp. 212-214
-
-
Kukkonen, J.P.1
-
221
-
-
0009448302
-
Über den anschaulichen Inhalt der quantentheoretischen Kinematik und Mechanik
-
Heisenberg, W. Über den anschaulichen Inhalt der quantentheoretischen Kinematik und Mechanik. Z. Phys. A-Hadron. Nucl. 1927, 43, 172-198.
-
(1927)
Z. Phys. A-Hadron. Nucl.
, vol.43
, pp. 172-198
-
-
Heisenberg, W.1
-
222
-
-
44849120336
-
Genetically encoded calcium indicators
-
Mank, M.; Griesbeck, O. Genetically encoded calcium indicators. Chem. Rev 2008, 108, 1550-1564.
-
(2008)
Chem. Rev.
, vol.108
, pp. 1550-1564
-
-
Mank, M.1
Griesbeck, O.2
-
223
-
-
73349108496
-
Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
-
Tian, L.; Hires, S. A.; Mao, T.; Huber, D.; Chiappe, M. E.; Chalasani, S. H.; Petreanu, L.; Akerboom, J.; McKinney, S. A.; Schreiter, E. R.; Bargmann, C. I.; Jayaraman, V.; Svoboda, K.; Looger, L. L. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nat. Methods 2009, 6, 875-881.
-
(2009)
Nat. Methods
, vol.6
, pp. 875-881
-
-
Tian, L.1
Hires, S.A.2
Mao, T.3
Huber, D.4
Chiappe, M.E.5
Chalasani, S.H.6
Petreanu, L.7
Akerboom, J.8
McKinney, S.A.9
Schreiter, E.R.10
Bargmann, C.I.11
Jayaraman, V.12
Svoboda, K.13
Looger, L.L.14
-
224
-
-
34249945258
-
Far-field optical nanoscopy
-
Hell, S. W. Far-field optical nanoscopy. Science 2007, 316, 1153-1158.
-
(2007)
Science
, vol.316
, pp. 1153-1158
-
-
Hell, S.W.1
-
225
-
-
0242322565
-
Toward fluorescence nanoscopy
-
Hell, S. W. Toward fluorescence nanoscopy. Nat. Biotechnol. 2003, 21, 1347-1355.
-
(2003)
Nat. Biotechnol.
, vol.21
, pp. 1347-1355
-
-
Hell, S.W.1
-
227
-
-
67650762824
-
Super-resolution fluorescence microscopy
-
Huang, B.; Bates, M.; Zhuang, X. Super-resolution fluorescence microscopy. Annu. Rev. Biochem. 2009, 78, 993-1016.
-
(2009)
Annu. Rev. Biochem.
, vol.78
, pp. 993-1016
-
-
Huang, B.1
Bates, M.2
Zhuang, X.3
-
228
-
-
0028460042
-
Breaking the diffraction resolution limit by stimulated emission: Stimulated-emission-depletion fluorescence microscopy
-
Hell, S. W.; Wichmann, J. Breaking the diffraction resolution limit by stimulated emission: Stimulated-emission-depletion fluorescence microscopy. Opt. Lett. 1994, 19, 780-782.
-
(1994)
Opt. Lett.
, vol.19
, pp. 780-782
-
-
Hell, S.W.1
Wichmann, J.2
-
229
-
-
0032607671
-
Subdiffraction resolution in far-field fluorescence microscopy
-
Klar, T. A.; Hell, S. W. Subdiffraction resolution in far-field fluorescence microscopy. Opt. Lett. 1999, 24, 954-956.
-
(1999)
Opt. Lett.
, vol.24
, pp. 954-956
-
-
Klar, T.A.1
Hell, S.W.2
-
230
-
-
33845360042
-
Ultra-high resolution imaging by fluorescence photoactivation localization microscopy
-
Hess, S. T.; Girirajan, T. P.; Mason, M. D. Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. Biophys. J. 2006, 91, 4258-4272.
-
(2006)
Biophys. J.
, vol.91
, pp. 4258-4272
-
-
Hess, S.T.1
Girirajan, T.P.2
Mason, M.D.3
-
231
-
-
33747179417
-
Imaging intracellular fluorescent proteins at nanometer resolution
-
Betzig, E.; Patterson, G. H.; Sougrat, R.; Lindwasser, O. W.; Olenych, S.; Bonifacino, J. S.; Davidson, M. W.; Lippincott-Schwartz, J.; Hess, H. F. Imaging intracellular fluorescent proteins at nanometer resolution. Science 2006, 313, 1642-1645.
-
(2006)
Science
, vol.313
, pp. 1642-1645
-
-
Betzig, E.1
Patterson, G.H.2
Sougrat, R.3
Lindwasser, O.W.4
Olenych, S.5
Bonifacino, J.S.6
Davidson, M.W.7
Lippincott-Schwartz, J.8
Hess, H.F.9
-
232
-
-
0000412790
-
Method of obtaining optical sectioning by using structured light in a conventional microscope
-
Neil, M. A. A.; Juskaitis, R.; Wilson, T. Method of obtaining optical sectioning by using structured light in a conventional microscope. Opt. Lett. 1997, 22, 1905-1907.
-
(1997)
Opt. Lett.
, vol.22
, pp. 1905-1907
-
-
Neil, M.A.A.1
Juskaitis, R.2
Wilson, T.3
-
233
-
-
24944539530
-
Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution
-
Gustafsson, M. G. Nonlinear structured-illumination microscopy: Wide-field fluorescence imaging with theoretically unlimited resolution. Proc. Natl. Acad. Sci. USA 2005, 102, 13081-13086.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 13081-13086
-
-
Gustafsson, M.G.1
-
234
-
-
0013277718
-
Coherent anti-Stokes Raman spectoscopy
-
Begley, R. F.; Harvey, A. B.; Byer, R. L. Coherent anti-Stokes Raman spectoscopy. Appl. Phys. Lett. 1974, 25, 387-390.
-
(1974)
Appl. Phys. Lett.
, vol.25
, pp. 387-390
-
-
Begley, R.F.1
Harvey, A.B.2
Byer, R.L.3
-
235
-
-
0028369038
-
Confocal microscopy with an increased detection aperture: Type-B 4pi confocal microscopy
-
Hell, S. W.; Stelzer, E. H.; Lindek, S.; Confocal microscopy with an increased detection aperture: Type-B 4pi confocal microscopy. Opt. Lett. 1994, 19, 222.
-
(1994)
Opt. Lett.
, vol.19
, pp. 222
-
-
Hell, S.W.1
Stelzer, E.H.2
Lindek, S.3
-
236
-
-
33749026335
-
Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM)
-
Rust, M. J.; Bates, M.; Zhuang, X. Sub-diffraction-limit imaging by stochastic optical reconstruction microscopy (STORM). Nat. Methods 2006, 3, 793-795.
-
(2006)
Nat. Methods
, vol.3
, pp. 793-795
-
-
Rust, M.J.1
Bates, M.2
Zhuang, X.3
-
237
-
-
33846565429
-
2+ signals and neuronal death in brain ischemia
-
2+ signals and neuronal death in brain ischemia. Stroke 2007, 38, 674-676.
-
(2007)
Stroke
, vol.38
, pp. 674-676
-
-
Bano, D.1
Nicotera, P.2
-
238
-
-
61849142791
-
Calcium signaling and neurodegenerative diseases
-
Bezprozvanny, I. Calcium signaling and neurodegenerative diseases. Trends Mol. Med. 2009, 15, 89-100.
-
(2009)
Trends Mol. Med.
, vol.15
, pp. 89-100
-
-
Bezprozvanny, I.1
|