Homer regulates the association of group 1 metabotropic glutamate receptors with multivalent complexes of Homer-related, synaptic proteins

Neuron

Volumn 21, Issue 4, 1998, Pages 707-716

  Xiao, Bo ^a   Tu, Jian Cheng ^a   Petralia, Ronald S ^b   Yuan, Joseph P ^a   Doan, Andrew ^a   Breder, Christopher D ^a   Ruggiero, Alicia ^a   Lanahan, Anthony A ^a   Wenthold, Robert J ^b   Worley, Paul F ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL INSTITUTE ON DEAFNESS AND OTHER COMMUNICATION DISORDERS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR; METABOTROPIC RECEPTOR; TRANSCRIPTION FACTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CROSS LINKING; DATA BASE; DNA LIBRARY; DROSOPHILA; EVOLUTION; GENE CONTROL; GENE EXPRESSION; IMMEDIATE EARLY GENE; NONHUMAN; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; RAT; RECEPTOR BINDING;

EID: 18544393408     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(00)80588-7     Document Type: Article

References (27)

1. Aigner, L., Arber, S., Kapfhammer, J.P., Laux, T., Schneider, C., Botteri, F., Brenner, H.R., and Caroni, P. (1995). Overexpression of the neural growth-associated protein GAP-43 induces nerve sprouting in the adult nervous system of transgenic mice. Cell 83, 269-278.
2. Baude, A., Nusser, Z., Roberts, J.D., Mulvihill, E., McIlhinney, R.A., and Somogyi, P. (1993). The metabotropic glutamate receptor (mGluR1α) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction. Neuron 11, 771-787.
3. Brakeman, P.R., Lanahan, A.A., O'Brien, R., Roche, K., Barnes, C.A., Huganir, R.L., and Worley, P.P. (1997). Homer: a protein that selectively binds metabotropic glutamate receptors. Nature 386, 284-288.
4. Doyle, D.A., Lee, A., Lewis, J., Kim, E., Sheng, M., and Mackinnon, R. (1996). Crystal structures of acomplexed and peptide-free membrane protein-binding domain: molecular basis of peptide recognition by pdz. Cell 85, 1067-1076.
5. Gertler, F.B., Niebuhr, K., Reinhard, M., Wehland, J., and Soriano, P. (1996). Mena, a relative of VASP and Drosophila Enabled, is implicated in the control of microfilament dynamics. Cell 87, 227-239.
6. Gill, S.R., Schroer, T.A., Szilak, l., Steuer, E.R., Sheetz, M.P., and Cleveland, D.W. (1991). Dynactin, a conserved, ubiquitously expressed component of an activator of vesicle motility mediated by cytoplasmic dynein. J. Cell Biol. 115, 1639-1650.
7. Gordon, J.W., Chesa, P.G., Nishimura, H., Rettig, W.J., Maccari, J.E., Endo, T., Seravalli, E., Seki, T., and Silver, J. (1987). Regulation of Thy-1 gene expression in transgenic mice. Cell 50, 445-452.
8. Haffner, C., Jarchau, T., Reinhard, M., Hoppe, J., Lohmann, S.M., and Walter, U. (1995). Molecular cloning, structural analysis and functional expression of the proline-rich focal adhesion and microfilament-associated protein VASP. EMBO J. 14, 19-27.
9. Huttner, W.B., Schiebler, W., Greengard, P., and De Camilli, P. (1983). Synapsin I (protein I), a nerve terminal-specific phosphoprotein: III. its association with synaptic vesicles studied in a highly purified synaptic vesicle preparation. J. Cell Biol. 96, 1374-1388.
10. Kato, A., Ozawa, F., Saitoh, Y., Hirai, K., and Inokuchi, K. (1997). vesl, a gene encoding VASP/Ena family related protein, is upregulated during seizure, long-term potentiation and synaptogenesis. FEBS Lett. 412, 183-189.
11. Lanahan, A., Lyford, G., Stevenson, G.S., Worley, P.F., and Barnes, C.A. (1997). Selective alteration of long-term potentiation-induced transcriptional response in hippocampus of aged, memory-impaired rats. J. Neurosci. 17, 2876-2885.
12. Li, R. (1997). Bee1, a yeast protein with homology to Wiscott-Aldrich syndrome protein, is critical for the assembly of cortical actin cytoskeleton. J. Cell Biol. 136, 649-658.
13. Lupas, A. (1996). Coiled coils: new structures and new functions. Trends Biochem. Sci. 21, 375-382.
14. Lyford, G., Yamagata, K., Kaufmann, W.E., Barnes, C.A., Sanders, L.K., Copeland, N.G., Gilbert, D.J., Jenkins, N.A., Lanahan, A.A., and Worley, P.F. (1995). Arc, a growth factor and activity-regulated gene encodes a novel cytoskeleton-associated protein that is enriched in neuronal dendrites. Neuron 14, 433-445.
15. Martin, L.J., Blackstone, C.D., Huganir, R.L., and Price, D.L. (1992). Cellular localization of a metabotropic glutamate receptor in rat brain. Neuron 9, 259-270.
16. Matsubara, A., Laake, J.H., Davanger, S., Usami, S., and Ottersen, O.P. (1996). Organization of AMPA receptor subunits at a glutamate synapse: a quantitative immunogold analysis of hair cell synapses in the rat organ of Corti. J. Neurosci. 16, 4457-4467.
17. Munro, S., and Pelham, H.R. (1987). A C-terminal signal prevents secretion of luminal ER proteins. Cell 48, 899-907.
18. Park, H.T., Kang, E.K., and Bae, K.W. (1997). Light regulates Homer mRNA expression in the rat suprachiasmatic nucleus. Brain Res. Mol. Brain Res. 52, 318-322.
19. Petralia, R.S., Wang, Y.X., Singh, S., Wu, C., Shi, L., Wei, J., and Wenthold, R.J. (1997). A monoclonal antibody shows discrete cellular and subcellular localizations of mGluR1α metabotropic glutamate receptors. J. Chem. Neuroanat. 13, 77-93.
20. Ponting, C.P., and Phillips, C. (1997). Identification of Homer as a homologue of the Wiskott-Aldrich syndrome protein suggests a receptor-binding function for WH1 domains. J. Mol. Med. 75, 769-771.
21. Shaw, G., and Kamen, R. (1986). A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degredation. Cell 46, 659-667.
22. Strehler, E.E., Strehler-Page, M.A., Perriard, J.C., Periasamy, M., and Nadal-Ginard, B. (1986). Complete nucleotide and encoded amino acid sequence of a mammalian myosin heavy chain gene: evidence against intron-dependent evolution of the rod. J. Mol. Biol. 190, 291-317.
23. Symons, M., Derry, J.M., Karlak, B., Jiang, S., Lemahieu, V., McCormick, F., Francke, U., and Abo, A. (1996). Wiskott-Aldrich syndrome protein, a novel effector for the GTPase CDC42Hs, is implicated in actin polymerization. Cell 84, 723-734.
24. Tu, J.C., Xiao, B., Yuan, J., Lanahan, A., Leoffert, K., Li, M., Linden, D., and Worley, P.F. (1998). Homer binds a novel proline-rich motif and links group 1 metabotropic glutamate receptors with IPS receptors. Neuron 21, 717-726.
25. Wang, Y.X., Wenthold, R.J., Ottersen, O.P., and Petralia, R.S. (1998). Endbulb synapses in the anteroventral cochlear nucleus express a specific subset of AMPA-type glutamate receptor subunits. J. Neurosci. 18, 1148-1160.
26. Worley, P.F., Cole, A.J., Saffen, D.W., and Baraban, J.M. (1990). Transcription factor regulation in brain: focus on activity and NMDA dependent regulation. In Molecular Mechanisms of Aging, K. Beyreuther and G. Schettler, eds. (Heidelberg: Springer-Verlag), pp. 62-76.
27. Yang, J.T., Laymon, R.A., and Goldstein, L.S. (1989). A three-domain structure of kinesin heavy chain revealed by DNA sequence and microtubule binding analyses. Cell 56, 879-889.