메뉴 건너뛰기




Volumn 20, Issue 1, 2000, Pages 22-33

Distinct roles of synaptic and extrasynaptic NMDA receptors in excitotoxicity

Author keywords

Actin filament; Cortical neurons; Cytochalasin D; Excitotoxicity; Latrunculin A; NMDA receptors; Oxygen glucose deprivation

Indexed keywords

CALCIUM; CYTOCHALASIN D; F ACTIN; GLUTAMIC ACID; LATRUNCULIN A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR STIMULATING AGENT; SYNAPSE RECEPTOR;

EID: 0034004473     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.20-01-00022.2000     Document Type: Article
Times cited : (218)

References (90)
  • 1
    • 0030957787 scopus 로고    scopus 로고
    • Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins
    • Abdel-Hamid KM, Tymianski M (1997) Mechanisms and effects of intracellular calcium buffering on neuronal survival in organotypic hippocampal cultures exposed to anoxia/aglycemia or to excitotoxins. J Neurosci 17:3538-3553.
    • (1997) J Neurosci , vol.17 , pp. 3538-3553
    • Abdel-Hamid, K.M.1    Tymianski, M.2
  • 2
    • 0029074299 scopus 로고
    • Molecular aspects of tetanus and botulinum neurotoxin poisoning
    • Ahnert-Hilger G, Bigalke H (1995) Molecular aspects of tetanus and botulinum neurotoxin poisoning. Prog Neurohiol 46:83-96.
    • (1995) Prog Neurohiol , vol.46 , pp. 83-96
    • Ahnert-Hilger, G.1    Bigalke, H.2
  • 3
    • 0032054473 scopus 로고    scopus 로고
    • Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: Differential attachment of NMDA versus AMPA receptors
    • Allison DW, Gelfand VI, Spector I, Craig AM (1998) Role of actin in anchoring postsynaptic receptors in cultured hippocampal neurons: differential attachment of NMDA versus AMPA receptors. J Neurosci 18:2423-2436.
    • (1998) J Neurosci , vol.18 , pp. 2423-2436
    • Allison, D.W.1    Gelfand, V.I.2    Spector, I.3    Craig, A.M.4
  • 4
    • 0027376769 scopus 로고
    • Nonvesicular release of neurotransmitter
    • Attwell D, Barbour B, Szatkowski M (1993) Nonvesicular release of neurotransmitter. Neuron 11:401-407.
    • (1993) Neuron , vol.11 , pp. 401-407
    • Attwell, D.1    Barbour, B.2    Szatkowski, M.3
  • 5
    • 0017350927 scopus 로고
    • Rat hippocampal neurons in dispersed cell culture
    • Banker GA, Cowan WM (1977) Rat hippocampal neurons in dispersed cell culture. Brain Res 126:397-342.
    • (1977) Brain Res , vol.126 , pp. 397-1342
    • Banker, G.A.1    Cowan, W.M.2
  • 6
    • 0023134919 scopus 로고
    • Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: A presynaptic locus of action for tetanus toxin
    • Bergey GK, Bigalke H, Nelson PG (1987) Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin. J Neurophysiol 57:121-131.
    • (1987) J Neurophysiol , vol.57 , pp. 121-131
    • Bergey, G.K.1    Bigalke, H.2    Nelson, P.G.3
  • 7
    • 0031012008 scopus 로고    scopus 로고
    • Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat
    • Bernard V, Somogyi P, Bolam JP (1997) Cellular, subcellular, and subsynaptic distribution of AMPA-type glutamate receptor subunits in the neostriatum of the rat. J Neurosci 17:819-833.
    • (1997) J Neurosci , vol.17 , pp. 819-833
    • Bernard, V.1    Somogyi, P.2    Bolam, J.P.3
  • 8
    • 0029848750 scopus 로고    scopus 로고
    • Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation
    • Bonfoco E, Leist M, Zhivotovsky B, Orrenius S, Lipton SA, Nicotera P (1996) Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation. J Neurochem 67:2484-2493.
    • (1996) J Neurochem , vol.67 , pp. 2484-2493
    • Bonfoco, E.1    Leist, M.2    Zhivotovsky, B.3    Orrenius, S.4    Lipton, S.A.5    Nicotera, P.6
  • 10
    • 0029959179 scopus 로고    scopus 로고
    • Cloning and characterization of postsynaptic density 93, a nitric oxide synthasc interacting protein
    • Brenman JE, Christopherson KS, Craven SE, McGee AW, Bredt DS (1996a) Cloning and characterization of postsynaptic density 93, a nitric oxide synthasc interacting protein. J Neurosci 16:7407-7415.
    • (1996) J Neurosci , vol.16 , pp. 7407-7415
    • Brenman, J.E.1    Christopherson, K.S.2    Craven, S.E.3    McGee, A.W.4    Bredt, D.S.5
  • 13
    • 85009295914 scopus 로고    scopus 로고
    • Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans
    • Brown JI, Baker AJ, Konasiewicz SJ, Moulton RJ (1998) Clinical significance of CSF glutamate concentrations following severe traumatic brain injury in humans. J Neurotrauma 15:253-263.
    • (1998) J Neurotrauma , vol.15 , pp. 253-263
    • Brown, J.I.1    Baker, A.J.2    Konasiewicz, S.J.3    Moulton, R.J.4
  • 14
    • 0028001367 scopus 로고
    • Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids
    • Bruno VMG, Goldberg MP, Dugan LL, Giffard RG, Choi DW (1994) Neuroprotective effect of hypothermia in cortical cultures exposed to oxygen-glucose deprivation or excitatory amino acids. J Neurochem 63:1398-1406.
    • (1994) J Neurochem , vol.63 , pp. 1398-1406
    • Bruno, V.M.G.1    Goldberg, M.P.2    Dugan, L.L.3    Giffard, R.G.4    Choi, D.W.5
  • 15
    • 0026492629 scopus 로고
    • The rat brain postsynaptic density fraction contains a homolog of the Drosophia discs-large tumor suppressor protein
    • Cho KO, Hunt CA, Kennedy MB (1992) The rat brain postsynaptic density fraction contains a homolog of the Drosophia discs-large tumor suppressor protein. Neuron 9:929-942.
    • (1992) Neuron , vol.9 , pp. 929-942
    • Cho, K.O.1    Hunt, C.A.2    Kennedy, M.B.3
  • 16
    • 0023137252 scopus 로고
    • Ionic dependence of glutamate neurotoxicity
    • Choi DW (1987) Ionic dependence of glutamate neurotoxicity. J Neurosci 7:369-379.
    • (1987) J Neurosci , vol.7 , pp. 369-379
    • Choi, D.W.1
  • 17
    • 0023753142 scopus 로고
    • Calcium-mediated neurotoxicity: Relationship to specific channel types and role in ischemic damage
    • Choi DW (1988) Calcium-mediated neurotoxicity: relationship to specific channel types and role in ischemic damage. Trends Neurosci 11:465-467.
    • (1988) Trends Neurosci , vol.11 , pp. 465-467
    • Choi, D.W.1
  • 18
    • 0023870521 scopus 로고
    • Pharmacology of glutamate neurotoxicity in cortical cell culture: Attenuation by NMDA antagonists
    • Choi DW, Koh JY, Peters S (1988) Pharmacology of glutamate neurotoxicity in cortical cell culture: attenuation by NMDA antagonists. J Neurosci 8:185-196.
    • (1988) J Neurosci , vol.8 , pp. 185-196
    • Choi, D.W.1    Koh, J.Y.2    Peters, S.3
  • 19
    • 0031023896 scopus 로고    scopus 로고
    • A direct comparison of the single-channel properties of synaptic and extrasynaptic NMDA receptors
    • Clark BA, Farrant M, Cull-Candy SG (1997) A direct comparison of the single-channel properties of synaptic and extrasynaptic NMDA receptors. J Neurosci 17:107-116.
    • (1997) J Neurosci , vol.17 , pp. 107-116
    • Clark, B.A.1    Farrant, M.2    Cull-Candy, S.G.3
  • 20
    • 0017396421 scopus 로고
    • The structure of postsynaptic densities isolated from dog cerebral cortex. I. Overall morphology and protein composition
    • Cohen RS, Blomberg F, Berzins K, Siekevitz P (1977) The structure of postsynaptic densities isolated from dog cerebral cortex. I. Overall morphology and protein composition. J Cell Biol 74:181-203.
    • (1977) J Cell Biol , vol.74 , pp. 181-203
    • Cohen, R.S.1    Blomberg, F.2    Berzins, K.3    Siekevitz, P.4
  • 21
    • 0023427610 scopus 로고
    • Effects of cytochalasin and phalloidin on actin
    • Cooper JA (1987) Effects of cytochalasin and phalloidin on actin. J Cell Biol 105:1473-1478.
    • (1987) J Cell Biol , vol.105 , pp. 1473-1478
    • Cooper, J.A.1
  • 22
    • 0028574167 scopus 로고
    • Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters
    • Craig AM, Blackstone CD, Huganir RL, Banker G (1994) Selective clustering of glutamate and gamma-aminobutyric acid receptors opposite terminals releasing the corresponding neurotransmitters. Proc Natl Acad Sci USA 91:12373-12377.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 12373-12377
    • Craig, A.M.1    Blackstone, C.D.2    Huganir, R.L.3    Banker, G.4
  • 23
    • 0030061340 scopus 로고    scopus 로고
    • AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked
    • David JC, Yamada KA, Bagwe MR, Goldberg MP (1996) AMPA receptor activation is rapidly toxic to cortical astrocytes when desensitization is blocked. J Neurosci 16:200-209.
    • (1996) J Neurosci , vol.16 , pp. 200-209
    • David, J.C.1    Yamada, K.A.2    Bagwe, M.R.3    Goldberg, M.P.4
  • 25
    • 0027178135 scopus 로고
    • Mechanism of nitric oxide-mediated neurotoxicity in primary brain cultures
    • Dawson VL, Dawson TM, Bartley DA, Uhl GR, Snyder SH (1993) Mechanism of nitric oxide-mediated neurotoxicity in primary brain cultures. J Neurosci 13:2651-2661.
    • (1993) J Neurosci , vol.13 , pp. 2651-2661
    • Dawson, V.L.1    Dawson, T.M.2    Bartley, D.A.3    Uhl, G.R.4    Snyder, S.H.5
  • 26
    • 0030900558 scopus 로고    scopus 로고
    • GRIP: A synaptic PDZ domain-containing protein that interacts with AMPA receptors
    • Dong H, O'Brien RJ, Fung ET, Lanahan AA, Worley PF, Huganir RL (1997) GRIP: a synaptic PDZ domain-containing protein that interacts with AMPA receptors [see comments]. Nature 386:279-284.
    • (1997) Nature , vol.386 , pp. 279-284
    • Dong, H.1    O'Brien, R.J.2    Fung, E.T.3    Lanahan, A.A.4    Worley, P.F.5    Huganir, R.L.6
  • 27
    • 0027262604 scopus 로고
    • Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain
    • During MJ, Spencer DD (1993) Extracellular hippocampal glutamate and spontaneous seizure in the conscious human brain [see comments]. Lancet 341:1607-1610.
    • (1993) Lancet , vol.341 , pp. 1607-1610
    • During, M.J.1    Spencer, D.D.2
  • 28
    • 0031972719 scopus 로고    scopus 로고
    • Splice variant-specific interaction of the NMDA receptor subunit NRI with neuronal intermediate filaments
    • Ehlers MD, Fung ET, O'Brien R, Huganir RL (1998) Splice variant-specific interaction of the NMDA receptor subunit NRI with neuronal intermediate filaments. J Neurosci 18:720-730.
    • (1998) J Neurosci , vol.18 , pp. 720-730
    • Ehlers, M.D.1    Fung, E.T.2    O'Brien, R.3    Huganir, R.L.4
  • 29
    • 0028097733 scopus 로고
    • The quantity of calcium that appears to induce neuronal death
    • Eimerl S, Schramm M (1994) The quantity of calcium that appears to induce neuronal death. J Neurochem 62:1223-1226.
    • (1994) J Neurochem , vol.62 , pp. 1223-1226
    • Eimerl, S.1    Schramm, M.2
  • 30
    • 0031038495 scopus 로고    scopus 로고
    • Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro
    • Faddis BT, Hasbani MJ, Goldberg MP (1997) Calpain activation contributes to dendritic remodeling after brief excitotoxic injury in vitro. J Neurosci 17:951-959.
    • (1997) J Neurosci , vol.17 , pp. 951-959
    • Faddis, B.T.1    Hasbani, M.J.2    Goldberg, M.P.3
  • 31
    • 0024365739 scopus 로고
    • The role of excitatory amino acids and NMDA receptors in traumatic brain injury
    • Faden AI, Demediuk P, Panter SS, Vink P (1989) The role of excitatory amino acids and NMDA receptors in traumatic brain injury. Science 244:798-800.
    • (1989) Science , vol.244 , pp. 798-800
    • Faden, A.I.1    Demediuk, P.2    Panter, S.S.3    Vink, P.4
  • 34
    • 0030807917 scopus 로고    scopus 로고
    • The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons
    • Furukawa K, Fu W, Li Y, Witke W, Kwiatkowski DJ, Mattson MP (1997) The actin-severing protein gelsolin modulates calcium channel and NMDA receptor activities and vulnerability to excitotoxicity in hippocampal neurons. J Neurosci 17:8178-8186.
    • (1997) J Neurosci , vol.17 , pp. 8178-8186
    • Furukawa, K.1    Fu, W.2    Li, Y.3    Witke, W.4    Kwiatkowski, D.J.5    Mattson, M.P.6
  • 36
    • 0027328680 scopus 로고
    • Combined oxygen and glucose deprivation in cortical cell culture: Calcium-dependent and calcium-independent mechanisms of neuronal injury
    • Goldberg MP, Choi DW (1993) Combined oxygen and glucose deprivation in cortical cell culture: calcium-dependent and calcium-independent mechanisms of neuronal injury. J Neurosci 13:3510-3524.
    • (1993) J Neurosci , vol.13 , pp. 3510-3524
    • Goldberg, M.P.1    Choi, D.W.2
  • 37
    • 0023489906 scopus 로고
    • N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture
    • Goldberg MP, Weiss JH, Pham PC, Choi DW (1987) N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture. J Pharmacol Exp Ther 243:784-791.
    • (1987) J Pharmacol Exp Ther , vol.243 , pp. 784-791
    • Goldberg, M.P.1    Weiss, J.H.2    Pham, P.C.3    Choi, D.W.4
  • 38
    • 0029978023 scopus 로고    scopus 로고
    • Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family
    • Gomperts SN (1996) Clustering membrane proteins: it's all coming together with the PSD-95/SAP90 protein family. [Review]. Cell 84:659-662.
    • (1996) Cell , vol.84 , pp. 659-662
    • Gomperts, S.N.1
  • 39
    • 0002329664 scopus 로고
    • Rat hippocampal neurons in low density culture
    • (Banker G, Goslin K, eds). Cambridge, MA: MIT
    • Goslin K, Banker G (1991) Rat hippocampal neurons in low density culture. In: Culturing nerve cells (Banker G, Goslin K, eds), pp 251-282. Cambridge, MA: MIT.
    • (1991) Culturing Nerve Cells , pp. 251-282
    • Goslin, K.1    Banker, G.2
  • 40
    • 0032403433 scopus 로고    scopus 로고
    • Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin
    • Halpain S, Hipolito A, Saffer L (1998) Regulation of F-actin stability in dendritic spines by glutamate receptors and calcineurin. J Neurosci 18:9835-9844.
    • (1998) J Neurosci , vol.18 , pp. 9835-9844
    • Halpain, S.1    Hipolito, A.2    Saffer, L.3
  • 41
    • 0028330166 scopus 로고
    • Dendritic spines: Cellular specializations imparting both stability and flexibility to synaptic function
    • Harris KM, Kater SB (1994) Dendritic spines: cellular specializations imparting both stability and flexibility to synaptic function. [Review]. Annu Rev Neurosci 17:341-371.
    • (1994) Annu Rev Neurosci , vol.17 , pp. 341-371
    • Harris, K.M.1    Kater, S.B.2
  • 44
    • 0032531787 scopus 로고    scopus 로고
    • Spine loss and other persistent alterations of hippocampal pyramidal cell dendrites in a model of early-onset epilepsy
    • Jiang M, Lee CL, Smith KL, Swann JW (1998) Spine loss and other persistent alterations of hippocampal pyramidal cell dendrites in a model of early-onset epilepsy. J Neurosci 18:8356-8368.
    • (1998) J Neurosci , vol.18 , pp. 8356-8368
    • Jiang, M.1    Lee, C.L.2    Smith, K.L.3    Swann, J.W.4
  • 45
    • 0030858245 scopus 로고    scopus 로고
    • N-type calcium channels in the developing rat hippocampus: Subunit, complex, and regional expression
    • Jones OT, Bernstein GM, Jones EJ, Jugloff DG, Law M, Wong W, Mills LR (1997) N-Type calcium channels in the developing rat hippocampus: subunit, complex, and regional expression. J Neurosci 17:6152-6164.
    • (1997) J Neurosci , vol.17 , pp. 6152-6164
    • Jones, O.T.1    Bernstein, G.M.2    Jones, E.J.3    Jugloff, D.G.4    Law, M.5    Wong, W.6    Mills, L.R.7
  • 46
    • 0031439662 scopus 로고    scopus 로고
    • Isoform specificity in the relationship of actin to dendritic spines
    • Kaech S, Fischer M, Doll T, Matus A (1997) Isoform specificity in the relationship of actin to dendritic spines. J Neurosci 17:9565-9572.
    • (1997) J Neurosci , vol.17 , pp. 9565-9572
    • Kaech, S.1    Fischer, M.2    Doll, T.3    Matus, A.4
  • 47
    • 0031172429 scopus 로고    scopus 로고
    • The postsynaptic density at glutamatergic synapses
    • Kennedy MB (1997) The postsynaptic density at glutamatergic synapses. [Review]. Trends Neurosci 20:264-268.
    • (1997) Trends Neurosci , vol.20 , pp. 264-268
    • Kennedy, M.B.1
  • 48
    • 0031456541 scopus 로고    scopus 로고
    • Tangential synaptic distribution of NMDA and AMPA receptors in rat neocortex
    • Kharazia VN, Weinberg RJ (1997) Tangential synaptic distribution of NMDA and AMPA receptors in rat neocortex. Neurosci Lett 238:41-44.
    • (1997) Neurosci Lett , vol.238 , pp. 41-44
    • Kharazia, V.N.1    Weinberg, R.J.2
  • 49
    • 0033152432 scopus 로고    scopus 로고
    • A role of actin filament in synaptic transmission and long-term potentiation
    • Kim CH, Lisman JE (1999) A role of actin filament in synaptic transmission and long-term potentiation. J Neurosci 19:4314-4324.
    • (1999) J Neurosci , vol.19 , pp. 4314-4324
    • Kim, C.H.1    Lisman, J.E.2
  • 50
    • 0030002705 scopus 로고    scopus 로고
    • Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases
    • Kim E, Sheng M (1996) Differential K+ channel clustering activity of PSD-95 and SAP97, two related membrane-associated putative guanylate kinases. Neuropharmacology 35:993-1000.
    • (1996) Neuropharmacology , vol.35 , pp. 993-1000
    • Kim, E.1    Sheng, M.2
  • 51
    • 0020051129 scopus 로고
    • Delayed neuronal death in the gerbil hippocampus following ischemia
    • Kirino T (1982) Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res 239:57-69.
    • (1982) Brain Res , vol.239 , pp. 57-69
    • Kirino, T.1
  • 53
    • 0029098659 scopus 로고
    • Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
    • Kornau HC, Schenker LT, Kennedy MB, Seeburg PH (1995) Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269:1737-1740.
    • (1995) Science , vol.269 , pp. 1737-1740
    • Kornau, H.C.1    Schenker, L.T.2    Kennedy, M.B.3    Seeburg, P.H.4
  • 55
    • 0033360169 scopus 로고    scopus 로고
    • Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons
    • Liao D, Zhang X. O'Brien R, Ehlers MD, Huganir RL (1999) Regulation of morphological postsynaptic silent synapses in developing hippocampal neurons. Nat Neurosci 2:37-43.
    • (1999) Nat Neurosci , vol.2 , pp. 37-43
    • Liao, D.1    Zhang, X.2    O'Brien, R.3    Ehlers, M.D.4    Huganir, R.L.5
  • 56
    • 0033366541 scopus 로고    scopus 로고
    • G-protein coupled receptors regulate NMDA receptors via the sequential activation of protein kinase C and Src
    • Lu WY, Xiong ZG, Lei S, Orser BA, Browning MD, Dudek E, MacDonald JF (1999) G-protein coupled receptors regulate NMDA receptors via the sequential activation of protein kinase C and Src. Nat Neurosci 2:331-338.
    • (1999) Nat Neurosci , vol.2 , pp. 331-338
    • Lu, W.Y.1    Xiong, Z.G.2    Lei, S.3    Orser, B.A.4    Browning, M.D.5    Dudek, E.6    MacDonald, J.F.7
  • 58
    • 0026763141 scopus 로고
    • Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin
    • Monyer H, Giffard RG, Hartley DM, Dugan LL, Goldberg MP, Choi DW (1992) Oxygen or glucose deprivation-induced neuronal injury in cortical cell cultures is reduced by tetanus toxin. Neuron 8:967-973.
    • (1992) Neuron , vol.8 , pp. 967-973
    • Monyer, H.1    Giffard, R.G.2    Hartley, D.M.3    Dugan, L.L.4    Goldberg, M.P.5    Choi, D.W.6
  • 60
    • 0029946167 scopus 로고    scopus 로고
    • Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases
    • Niethammer M, Kim E, Sheng M (1996) Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases. J Neurosci 16:2157-2163.
    • (1996) J Neurosci , vol.16 , pp. 2157-2163
    • Niethammer, M.1    Kim, E.2    Sheng, M.3
  • 61
    • 0032102070 scopus 로고    scopus 로고
    • Molecular mechanisms of glutamate receptor clustering at excitatory synapses
    • O'Brien R, Lau LF, Huganir RL (1998a) Molecular mechanisms of glutamate receptor clustering at excitatory synapses. Curr Opin Neurobiol 8:364-369.
    • (1998) Curr Opin Neurobiol , vol.8 , pp. 364-369
    • O'Brien, R.1    Lau, L.F.2    Huganir, R.L.3
  • 63
    • 0030175149 scopus 로고    scopus 로고
    • Rapid alterations in dendritic morphology during sublethal hypoxia or glutamate receptor activation
    • Park JS, Bateman MC, Goldberg MP (1996) Rapid alterations in dendritic morphology during sublethal hypoxia or glutamate receptor activation. Neurobiol Dis 3:215-227.
    • (1996) Neurobiol Dis , vol.3 , pp. 215-227
    • Park, J.S.1    Bateman, M.C.2    Goldberg, M.P.3
  • 64
    • 0023390566 scopus 로고
    • Delayed hippocampal damage in humans following cardiorespiratory arrest
    • Petito CK, Feldmann E, Pulsinelli WA, Plum F (1987) Delayed hippocampal damage in humans following cardiorespiratory arrest. Neurology 37:1281-1286.
    • (1987) Neurology , vol.37 , pp. 1281-1286
    • Petito, C.K.1    Feldmann, E.2    Pulsinelli, W.A.3    Plum, F.4
  • 65
    • 0031171361 scopus 로고    scopus 로고
    • PDZ domains: Targeting signalling molecules to sub-membranous sites
    • Ponting CP, Phillips C, Davies KE, Blake DJ (1997) PDZ domains: targeting signalling molecules to sub-membranous sites. [Review]. BioEssays 19:469-479.
    • (1997) BioEssays , vol.19 , pp. 469-479
    • Ponting, C.P.1    Phillips, C.2    Davies, K.E.3    Blake, D.J.4
  • 66
    • 0030819659 scopus 로고    scopus 로고
    • Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons
    • Rao A, Craig AM (1997) Activity regulates the synaptic localization of the NMDA receptor in hippocampal neurons. Neuron 19:801-812.
    • (1997) Neuron , vol.19 , pp. 801-812
    • Rao, A.1    Craig, A.M.2
  • 67
    • 0027258451 scopus 로고
    • Calcium-induced actin depolymerization reduces NMDA channel activity
    • Rosenmund C, Westbrook GL (1993) Calcium-induced actin depolymerization reduces NMDA channel activity. Neuron 10:805-814.
    • (1993) Neuron , vol.10 , pp. 805-814
    • Rosenmund, C.1    Westbrook, G.L.2
  • 68
    • 0028965220 scopus 로고
    • Synaptic NMDA receptor channels have a low open probability
    • Rosenmund C. Feltz A, Westbrook GL (1995) Synaptic NMDA receptor channels have a low open probability. J Neurosci 15:2788-2795.
    • (1995) J Neurosci , vol.15 , pp. 2788-2795
    • Rosenmund, C.1    Feltz, A.2    Westbrook, G.L.3
  • 69
    • 0020585505 scopus 로고
    • Synaptic activity mediates death of hypoxic neurons
    • Rothman SM (1983) Synaptic activity mediates death of hypoxic neurons. Science 220:536-537.
    • (1983) Science , vol.220 , pp. 536-537
    • Rothman, S.M.1
  • 70
    • 0021125414 scopus 로고
    • Synaptic release of excitatory amino acid neuro-transmitter mediates anoxic neuronal death
    • Rothman SM (1984) Synaptic release of excitatory amino acid neuro-transmitter mediates anoxic neuronal death. J Neurosci 4:1884-1891.
    • (1984) J Neurosci , vol.4 , pp. 1884-1891
    • Rothman, S.M.1
  • 71
    • 0022620257 scopus 로고
    • Glutamate and the pathophysiology of hypoxic-ischemic brain damage
    • Rothman SM, Olney JW (1986) Glutamate and the pathophysiology of hypoxic-ischemic brain damage. Ann Neurol 19:105-111.
    • (1986) Ann Neurol , vol.19 , pp. 105-111
    • Rothman, S.M.1    Olney, J.W.2
  • 73
    • 0030887032 scopus 로고    scopus 로고
    • Determination of the time-course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified multi-well plate fluorescence scanner
    • Sattler R, Charlton MP, Hafner M, Tymianski M (1997) Determination of the time-course and extent of neurotoxicity at defined temperatures in cultured neurons using a modified multi-well plate fluorescence scanner. J Cereb Blood Flow Metab 17:455-463.
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 455-463
    • Sattler, R.1    Charlton, M.P.2    Hafner, M.3    Tymianski, M.4
  • 74
    • 0031792791 scopus 로고    scopus 로고
    • Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity
    • Sattler R, Charlton MP, Hafner M, Tymianski M (1998) Distinct influx pathways, not calcium load, determine neuronal vulnerability to calcium neurotoxicity. J Neurochem 71:2349-2364.
    • (1998) J Neurochem , vol.71 , pp. 2349-2364
    • Sattler, R.1    Charlton, M.P.2    Hafner, M.3    Tymianski, M.4
  • 75
    • 0033546347 scopus 로고    scopus 로고
    • Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein
    • Sattler R, Xiong Z, Lu WY, Hafner M, MacDonald JF, Tymianski M (1999) Specific coupling of NMDA receptor activation to nitric oxide neurotoxicity by PSD-95 protein. Science 284:1845-1848.
    • (1999) Science , vol.284 , pp. 1845-1848
    • Sattler, R.1    Xiong, Z.2    Lu, W.Y.3    Hafner, M.4    MacDonald, J.F.5    Tymianski, M.6
  • 76
    • 0030857117 scopus 로고    scopus 로고
    • N-methyl-D-aspartate evokes rapid net depolymerization of filamentous actin in cultured rat cerebellar granule cells
    • Shorte SL (1997) N-methyl-D-aspartate evokes rapid net depolymerization of filamentous actin in cultured rat cerebellar granule cells. J Neurophysiol 78:1135-1143.
    • (1997) J Neurophysiol , vol.78 , pp. 1135-1143
    • Shorte, S.L.1
  • 77
    • 0020698663 scopus 로고
    • Latrunculins: Novel marine toxins that disrupt microfilament organization in cultured cells
    • Spector I, Shochet NR, Kashman Y, Groweiss A (1983) Latrunculins: novel marine toxins that disrupt microfilament organization in cultured cells. Science 219:493-495.
    • (1983) Science , vol.219 , pp. 493-495
    • Spector, I.1    Shochet, N.R.2    Kashman, Y.3    Groweiss, A.4
  • 78
    • 0024360298 scopus 로고
    • Latrunculins-novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D
    • Spector I, Shochet NR, Blasberger D, Kashman Y (1989) Latrunculins-novel marine macrolides that disrupt microfilament organization and affect cell growth: I. Comparison with cytochalasin D. Cell Motil Cytoskel 13:127-144.
    • (1989) Cell Motil Cytoskel , vol.13 , pp. 127-144
    • Spector, I.1    Shochet, N.R.2    Blasberger, D.3    Kashman, Y.4
  • 80
    • 0028024908 scopus 로고
    • Triggering and execution of neuronal death in brain ischemia: Two phases of glutamate release by different mechanisms
    • Szatkowski M, Attwell D (1994) Triggering and execution of neuronal death in brain ischemia: two phases of glutamate release by different mechanisms. Trends Neurosci 17:359-365.
    • (1994) Trends Neurosci , vol.17 , pp. 359-365
    • Szatkowski, M.1    Attwell, D.2
  • 81
    • 0024678383 scopus 로고
    • Traumatic neuronal injury in vitro is attenuated by NMDA antagonists
    • Tecoma ES, Monyer H, Goldberg MP, Choi DW (1989) Traumatic neuronal injury in vitro is attenuated by NMDA antagonists. Neuron 2:1541-1545.
    • (1989) Neuron , vol.2 , pp. 1541-1545
    • Tecoma, E.S.1    Monyer, H.2    Goldberg, M.P.3    Choi, D.W.4
  • 82
    • 0029691578 scopus 로고    scopus 로고
    • Cytosolic calcium concentrations and cell death in vitro
    • (Siesjo BK, Wieloch T, eds). Philadelphia: Lippincott-Raven
    • Tymianski M (1996) Cytosolic calcium concentrations and cell death in vitro. In: Advances in neurology: cellular and molecular mechanisms of ischemic brain damage (Siesjo BK, Wieloch T, eds), pp 85-105. Philadelphia: Lippincott-Raven.
    • (1996) Advances in Neurology: Cellular and Molecular Mechanisms of Ischemic Brain Damage , pp. 85-105
    • Tymianski, M.1
  • 83
    • 0027497936 scopus 로고
    • Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons
    • Tymianski M, Charlton MP, Carlen PL, Tator CH (1993) Source specificity of early calcium neurotoxicity in cultured embryonic spinal neurons. J Neurosci 13:2085-2104.
    • (1993) J Neurosci , vol.13 , pp. 2085-2104
    • Tymianski, M.1    Charlton, M.P.2    Carlen, P.L.3    Tator, C.H.4
  • 84
    • 0031852221 scopus 로고    scopus 로고
    • A characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity
    • Tymianski M, Sattler R, Zabramski JM, Spetzler RF (1998) A characterization of neuroprotection from excitotoxicity by moderate and profound hypothermia in cultured cortical neurons unmasks a temperature-insensitive component of glutamate neurotoxicity. J Cereb Blood Flow Metab 18:848-867.
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 848-867
    • Tymianski, M.1    Sattler, R.2    Zabramski, J.M.3    Spetzler, R.F.4
  • 85
    • 0029977616 scopus 로고    scopus 로고
    • Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons
    • Wenthold RJ, Petralia RS, Blahos J, II, Niedzielski AS (1996) Evidence for multiple AMPA receptor complexes in hippocampal CA1/CA2 neurons. J Neurosci 16:1982-1989.
    • (1996) J Neurosci , vol.16 , pp. 1982-1989
    • Wenthold, R.J.1    Petralia, R.S.2    Blahos J. II3    Niedzielski, A.S.4
  • 86
  • 87
    • 0032519871 scopus 로고    scopus 로고
    • Differential regional expression and ultrastructural localization of a-Actinin-2, a putative NMDA receptor-anchoring protein, in rat brain
    • Wyszynski M, Kharazia V, Shanghvi R, Rao A, Beggs AH, Craig AM, Weinberg RJ, Sheng M (1998) Differential regional expression and ultrastructural localization of a-Actinin-2, a putative NMDA receptor-anchoring protein, in rat brain. J Neurosci 18:1383-1392.
    • (1998) J Neurosci , vol.18 , pp. 1383-1392
    • Wyszynski, M.1    Kharazia, V.2    Shanghvi, R.3    Rao, A.4    Beggs, A.H.5    Craig, A.M.6    Weinberg, R.J.7    Sheng, M.8
  • 88
    • 0031011668 scopus 로고    scopus 로고
    • Extracellular calcium sensed by a novel cation channel in hippocampal neurons
    • Xiong Z, Lu W, MacDonald JF (1997) Extracellular calcium sensed by a novel cation channel in hippocampal neurons. Proc Natl Acad Sci USA 94:7012-7017.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7012-7017
    • Xiong, Z.1    Lu, W.2    MacDonald, J.F.3
  • 89
    • 0029065159 scopus 로고
    • Dendritic spines as basic functional units of neuronal integration
    • Yuste R, Denk W (1995) Dendritic spines as basic functional units of neuronal integration. Nature 375:682-684.
    • (1995) Nature , vol.375 , pp. 682-684
    • Yuste, R.1    Denk, W.2
  • 90
    • 0032142987 scopus 로고    scopus 로고
    • Calmodulin mediates calcium-dependent inactivation of N-methyl-D-aspartate receptors
    • Zhang S, Ehlers MD, Bernhardt JP, Su CT, Huganir RL (1998) Calmodulin mediates calcium-dependent inactivation of N-methyl-D-aspartate receptors. Neuron 21:443-453.
    • (1998) Neuron , vol.21 , pp. 443-453
    • Zhang, S.1    Ehlers, M.D.2    Bernhardt, J.P.3    Su, C.T.4    Huganir, R.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.