Subunit-specific NMDA receptor trafficking to synapses

Neuron

Volumn 35, Issue 2, 2002, Pages 345-353

  Barria, Andres ^a   Malinow, Roberto ^a  

^a Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPA RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; RECEPTOR SUBUNIT;

AGE; ARTICLE; BRAIN NERVE CELL; BRAIN SLICE; CONTROLLED STUDY; HIPPOCAMPUS; HUMAN; HUMAN CELL; NEUROMODULATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN TRANSPORT; SYNAPSE; SYNAPTIC TRANSMISSION;

EID: 0037130451     PISSN: 08966273     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0896-6273(02)00776-6     Document Type: Article

References (54)

1. Regulation of AMPA receptor endocytosis by a signaling mechanism shared with LTD
2. Relationship between N-methyl-D-aspartate receptor NR1 splice variants and NR2 subunits
3. Control by asparagine residues of calcium permeability and magnesium blockade in the NMDA receptor
4. The C-terminal domains of the GABA(b) receptor subunits mediate intracellular trafficking but are not required for receptor signaling
5. Activity-dependent decrease in NMDA receptor responses during development of the visual cortex
6. Integrins mediate functional pre- and postsynaptic maturation at a hippocampal synapse
7. Calcium: Still center-stage in hypoxic-ischemic neuronal death
8. LTP and activity-dependent synaptogenesis: The more alike they are, the more different they become
9. A critical period for long-term potentiation at thalamocortical synapses
10. 2+ signaling requirements for long-term depression in the hippocampus
11. EphB receptors interact with NMDA receptors and regulate excitatory synapse formation
12. The glutamate receptor ion channels
13. Long-term depression at thalamocortical synapses in developing rat somatosensory cortex
14. NR2A subunit expression shortens NMDA receptor synaptic currents in developing neocortex
15. PDZ domains in synapse assembly and signalling
16. Turnover analysis of glutamate receptors identifies a rapidly degraded pool of the N-methyl-D-aspartate receptor subunit, NR1, in cultured cerebellar granule cells
17. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95
18. Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice
19. Regional and developmental heterogeneity in splicing of the rat brain NMDAR1 mRNA
20. Distinct molecular mechanisms and divergent endocytotic pathways of AMPA receptor internalization
21. Barrel cortex critical period plasticity is independent of changes in NMDA receptor subunit composition
22. Actions of ketamine, phencyclidine and MK-801 on NMDA receptor currents in cultured mouse hippocampal neurones
23. Two-photon imaging in living brain slices
24. Synaptic calcium transients in single spines indicate that NMDA receptors are not saturated
25. Functional characterization of a heteromeric NMDA receptor channel expressed from cloned cDNAs
26. Heteromeric NMDA receptors: Molecular and functional distinction of subtypes
27. Developmental and regional expression in the rat brain and functional properties of four NMDA receptors
28. Identification by mutagenesis of a Mg(2+)-block site of the NMDA receptor channel
29. Role of the carboxy-terminal region of the GluR epsilon2 subunit in synaptic localization of the NMDA receptor channel
30. Alternative splicing generates functionally distinct N-methyl-D-aspartate receptors
31. Mutagenesis reveals a role for ABP/GRIP binding to GluR2 in synaptic surface accumulation of the AMPA receptor
32. C-terminal interaction is essential for surface trafficking but not for heteromeric assembly of GABA(b) receptors
33. Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons
34. Visual experience and deprivation bidirectionally modify the composition and function of NMDA receptors in visual cortex
35. Effect of transgenic overexpression of NR2B on NMDA receptor function and synaptic plasticity in visual cortex
36. Critical PDZ interactions by GluR1 and GluR2 required at different subcellular sites
37. Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo
38. An NMDA receptor ER retention signal regulated by phosphorylation and alternative splicing
39. Ligand-gated ion channel interactions with cytoskeletal and signaling proteins
40. Pdz domains and the organization of supramolecular complexes
41. Changing subunit composition of heteromeric NMDA receptors during development of rat cortex
42. Subunit-specific rules governing ampa receptor trafficking to synapses in hippocampal pyramidal neurons
43. Dysfunctions in mice by NMDA receptor point mutations NR1(N598Q) and NR1(N598R)
44. Importance of the intracellular domain of NR2 subunits for NMDA receptor function in vivo
45. PDZ domain suppression of an ER retention signal in NMDA receptor NR1 splice variants
46. C-terminal truncation of NR2A subunits impairs synaptic but not extrasynaptic localization of NMDA receptors
47. Increased contribution of NR2A subunit to synaptic NMDA receptors in developing rat cortical neurons
48. The incorporation of NMDA receptors with a distinct subunit composition at nascent hippocampal synapses in vitro
49. A use-dependent tyrosine dephosphorylation of NMDA receptors is independent of ion flux
50. Ifenprodil discriminates subtypes of the N-methyl-D-aspartate receptor: Selectivity and mechanisms at recombinant heteromeric receptors
51. An ER retention signal explains differences in surface expression of NMDA and AMPA receptor subunits
52. Postnatal synaptic potentiation: Delivery of GluR4-containing AMPA receptors by spontaneous activity
53. Neurobiology of disease
54. Calcium- and activity-dependent synaptic plasticity