Efficacy and safety of memantine, an NMDA-type open-channel blocker, for reduction of retinal injury associated with experimental glaucoma in rat and monkey

Survey of Ophthalmology

Volumn 45, Issue 6, 2001, Pages

  Hare, William ^a   WoldeMussie, Elizabeth ^a   Lai, Ron ^a   Ton, Hau ^a   Ruiz, Guadalupe ^a   Feldmann, Barbara ^a   Wijono, Mercy ^a   Chun, Teresa ^a   Wheeler, Larry ^a  

^a ALLERGAN INC   (United States)

Author keywords

Cell death; Excitotoxicity; Glaucoma; Glutamate; Memantine; NMDA; NMDA antagonist; Retina

Indexed keywords

MEMANTINE; GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; AMINO ACID RECEPTOR BLOCKING AGENT; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; ELECTRORETINOGRAM; EVOKED VISUAL RESPONSE; GLAUCOMA; MONKEY; PARKINSON DISEASE; PRIORITY JOURNAL; RAT; RETINA GANGLION CELL; RETINA INJURY; TREATMENT OUTCOME; VISUAL SYSTEM; AMPLITUDE MODULATION; ANIMAL TISSUE; CONFERENCE PAPER; MALE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; RETINA; SPECIES DIFFERENCE; VISION; ANIMAL; CELL COUNT; CELL SURVIVAL; DRUG ANTAGONISM; ELECTRORETINOGRAPHY; INTRAOCULAR PRESSURE; LASER COAGULATION; MACACA; PATHOLOGY; REPERFUSION INJURY; SAFETY; WISTAR RAT;

ANIMALS; CELL COUNT; CELL SURVIVAL; ELECTRORETINOGRAPHY; EVOKED POTENTIALS, VISUAL; EXCITATORY AMINO ACID ANTAGONISTS; GLAUCOMA; INTRAOCULAR PRESSURE; LASER COAGULATION; MACACA FASCICULARIS; MALE; MEMANTINE; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; REPERFUSION INJURY; RETINAL GANGLION CELLS; SAFETY;

EID: 0034766994     PISSN: 00396257     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-6257(01)00200-4     Document Type: Article

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