메뉴 건너뛰기




Volumn 3, Issue 1, 2009, Pages 117-122

Clinical efficacy and neuroprotective effects of brimonidine in the management of glaucoma and ocular hypertension

Author keywords

Brimonidine; Clinical effectiveness; Neuroprotection; Tolerability

Indexed keywords

APRACLONIDINE; BENZALKONIUM CHLORIDE; BETAXOLOL; BRIMONIDINE; BRIMONIDINE PLUS TIMOLOL; CHLORINE DIOXIDE; CLONIDINE; DORZOLAMIDE; DORZOLAMIDE PLUS TIMOLOL; LATANOPROST; PURITE; TIMOLOL; UNCLASSIFIED DRUG;

EID: 77950354281     PISSN: 11775467     EISSN: 11775483     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (25)

References (60)
  • 2
    • 0029957176 scopus 로고    scopus 로고
    • Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study
    • Mitchell P, Smith W, Attebo K, et al. Prevalence of open-angle glaucoma in Australia. The Blue Mountains Eye Study. Ophthalmology. 1996;103(10):1661-9.
    • (1996) Ophthalmology , vol.103 , Issue.10 , pp. 1661-1669
    • Mitchell, P.1    Smith, W.2    Attebo, K.3
  • 3
    • 0026641023 scopus 로고
    • Prevalence of glaucoma. The Beaver Dam Eye Study
    • Klein BE, Klein R, Spinsel WE, et al. Prevalence of glaucoma. The Beaver Dam Eye Study. Ophthalmology. 1992;99:1499-504.
    • (1992) Ophthalmology , vol.99 , pp. 1499-1504
    • Klein, B.E.1    Klein, R.2    Spinsel, W.E.3
  • 4
    • 0033808223 scopus 로고    scopus 로고
    • The Advanced Glaucoma Intervention Study (AGIS):7. The relationship between control of intraocular pressure and visual field deterioration
    • The AGIS investigators
    • The AGIS investigators. The Advanced Glaucoma Intervention Study (AGIS):7. The relationship between control of intraocular pressure and visual field deterioration. Am J Ophthalol. 2000;130:429-40.
    • (2000) Am J Ophthalol , vol.130 , pp. 429-440
  • 5
    • 77953409986 scopus 로고    scopus 로고
    • Neuroprotection and Glaucoma; Current Concepts. 2002 Oxford Institiute.
    • Neuroprotection and Glaucoma; Current Concepts. 2002 Oxford Institiute.
  • 6
    • 0033044222 scopus 로고    scopus 로고
    • Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients
    • Toris CB, Camras CB, Yablonski ME. Acute versus chronic effects of brimonidine on aqueous humor dynamics in ocular hypertensive patients. Am J Ophthalmol. 1999;128(1):8-14.
    • (1999) Am J Ophthalmol , vol.128 , Issue.1 , pp. 8-14
    • Toris, C.B.1    Camras, C.B.2    Yablonski, M.E.3
  • 7
    • 0034189105 scopus 로고    scopus 로고
    • The evolving pharmacotherapeutic pro. le of brimonidine, an alpha2-adrenergic agonist, after four years of continuous use
    • Cantor LB. The evolving pharmacotherapeutic pro. le of brimonidine, an alpha2-adrenergic agonist, after four years of continuous use. Expert Opin Pharmacother. 2000;1:815-34.
    • (2000) Expert Opin Pharmacother , vol.1 , pp. 815-834
    • Cantor, L.B.1
  • 8
    • 0029774226 scopus 로고    scopus 로고
    • Development and use of brimonidine in treating acute and chronic elevations of intraocular pressure, a review of safety, efficacy, dose response and dosing studies
    • Walters TR. Development and use of brimonidine in treating acute and chronic elevations of intraocular pressure, a review of safety, efficacy, dose response and dosing studies. Surv Ophthalmol. 1996;41:S19-S26.
    • (1996) Surv Ophthalmol , vol.41
    • Walters, T.R.1
  • 9
    • 0032725983 scopus 로고    scopus 로고
    • Is neuroprotection a viable therapy for glaucoma?
    • Weinreb RN, Levin LA. Is neuroprotection a viable therapy for glaucoma? Arch Ophthalmol. 1999;117:1540-4.
    • (1999) Arch Ophthalmol , vol.117 , pp. 1540-1544
    • Weinreb, R.N.1    Levin, L.A.2
  • 10
    • 0034754862 scopus 로고    scopus 로고
    • Role of alph2adrenergic receptors in neuroprotection and glaucoma
    • Wheeler LA, Gil DW, WoldeMussie E. Role of alph2adrenergic receptors in neuroprotection and glaucoma. Surv Ophthalmol. 2001;45(Suppl 3):S290-294.
    • (2001) Surv Ophthalmol , vol.45 , Issue.SUPPL. 3
    • Wheeler, L.A.1    Gil, D.W.2    WoldeMussie, E.3
  • 11
    • 0032587014 scopus 로고    scopus 로고
    • Characterization of alpha2 adrenergic receptor subtypes in human ocular tissue. Ivest
    • Bylund DB, Chacko DM. Characterization of alpha2 adrenergic receptor subtypes in human ocular tissue. Ivest Ophthalmol Vis Sci. 1999;40:2299-306,
    • (1999) Ophthalmol Vis Sci , vol.40 , pp. 2299-2306
    • Bylund, D.B.1    Chacko, D.M.2
  • 13
    • 0035082121 scopus 로고    scopus 로고
    • Vitreous concentrations of topically applied brimonidine tartrate 0.2%
    • Kent A, Nussdorf J, David R, et al. Vitreous concentrations of topically applied brimonidine tartrate 0.2%. Ophthalmology. 2001;108:784-7.
    • (2001) Ophthalmology , vol.108 , pp. 784-787
    • Kent, A.1    Nussdorf, J.2    David, R.3
  • 14
    • 0034754201 scopus 로고    scopus 로고
    • Neuroprotection of retinal ganglion cells by brimonidine in rats with laser- induced chronic ocular hypertension
    • WoldeMussie E, Ruiz G, Wijono M, Wheeler LA. Neuroprotection of retinal ganglion cells by brimonidine in rats with laser- induced chronic ocular hypertension. Invest Ophthalmol Vis Sci. 2001:42:2849-55.
    • (2001) Invest Ophthalmol Vis Sci , vol.42 , pp. 2849-2855
    • WoldeMussie, E.1    Ruiz, G.2    Wijono, M.3    Wheeler, L.A.4
  • 15
    • 42749091665 scopus 로고    scopus 로고
    • Retinal ganglion cell neuroprortection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments
    • Hernandez M, Urcola JH, Vecino E. Retinal ganglion cell neuroprortection in a rat model of glaucoma following brimonidine, latanoprost or combined treatments. Exp Eye Res. 2008;86:798-806.
    • (2008) Exp Eye Res , vol.86 , pp. 798-806
    • Hernandez, M.1    Urcola, J.H.2    Vecino, E.3
  • 16
    • 0032904676 scopus 로고    scopus 로고
    • From the lab to the clinic: Activation of an alpha-2 agonist pathway is neuroprtoective in models of retinal and optic nerve injury
    • Wheeler LA, Lai R, WolenMussie E. From the lab to the clinic: activation of an alpha-2 agonist pathway is neuroprtoective in models of retinal and optic nerve injury. Eur J Ophthalmol. 1999;9(Suppl 1):S17-21.
    • (1999) Eur J Ophthalmol , vol.9 , Issue.SUPPL. 1
    • Wheeler, L.A.1    Lai, R.2    WolenMussie, E.3
  • 17
    • 0035198185 scopus 로고    scopus 로고
    • Alpha(2)-adrenoceptoragonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischaemia
    • Donello JE, Padillo EU, Webster ML, et al. Alpha(2)-adrenoceptoragonists inhibit vitreal glutamate and aspartate accumulation and preserve retinal function after transient ischaemia. J Pharmacol Exp Ther. 2001;296:216-23.
    • (2001) J Pharmacol Exp Ther , vol.296 , pp. 216-223
    • Donello, J.E.1    Padillo, E.U.2    Webster, M.L.3
  • 18
    • 33645174976 scopus 로고    scopus 로고
    • Alpha-2 adrenergic receptor activation by brimondine reduces neuronal apoptosis through Akt (ptrotien Kinase B) dependent new synthesis of BCL-2
    • Wheeler LA, Tatton NA, Elstner M, et al. Alpha-2 adrenergic receptor activation by brimondine reduces neuronal apoptosis through Akt (ptrotien Kinase B) dependent new synthesis of BCL-2. Invest Opthalmol Vis Sci. 2001;42:S411.
    • (2001) Invest Opthalmol Vis Sci , vol.42
    • Wheeler, L.A.1    Tatton, N.A.2    Elstner, M.3
  • 19
    • 9144241000 scopus 로고    scopus 로고
    • Randomised controlled trial comparing the effect of brimonidine and timolol on visual field loss after acute primary angle closure
    • Aung T, Oen FT, Wong HT, et al. Randomised controlled trial comparing the effect of brimonidine and timolol on visual field loss after acute primary angle closure. Br J Ophthalmol. 2004;88(1):88-94.
    • (2004) Br J Ophthalmol , vol.88 , Issue.1 , pp. 88-94
    • Aung, T.1    Oen, F.T.2    Wong, H.T.3
  • 20
    • 25844525413 scopus 로고    scopus 로고
    • Topical brimonidine reduces collateral damage caused by laser photocoagulation for choroidal neovascularization
    • Ferencz JR, Gilady G, Harel O et al. Topical brimonidine reduces collateral damage caused by laser photocoagulation for choroidal neovascularization. Graefes Arch Clin Exp Ophthalmol. 2005;243:877-80.
    • (2005) Graefes Arch Clin Exp Ophthalmol , vol.243 , pp. 877-880
    • Ferencz, J.R.1    Gilady, G.2    Harel, O.3
  • 21
    • 30544452525 scopus 로고    scopus 로고
    • Comparison of the effects of brimonidine 0.2% and timolo 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: A prospective, unmasked study
    • Dec;
    • Tsai JC, Chang HW: Comparison of the effects of brimonidine 0.2% and timolo 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: a prospective, unmasked study. J Ocul Pharmacol Ther. 2005 Dec;21(6):474-82.
    • (2005) J Ocul Pharmacol Ther , vol.21 , Issue.6 , pp. 474-482
    • Tsai, J.C.1    Chang, H.W.2
  • 22
    • 63449099637 scopus 로고    scopus 로고
    • Is there a non IOP- related effect of brimonidine on visual field progression in human glaucoma?
    • ARVO E-abstract 2298
    • Gandolfi SA, Sangermani C, Cimino L. et al. Is there a non IOP- related effect of brimonidine on visual field progression in human glaucoma? IOVS, 2004(45) ARVO E-abstract 2298.
    • IOVS , vol.2004 , Issue.45
    • Gandolfi, S.A.1    Sangermani, C.2    Cimino, L.3
  • 23
    • 0346887097 scopus 로고    scopus 로고
    • Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: A case for neuroprotection
    • Evans DW, Hosking SL, Gherghel D, Barlett JD. Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: a case for neuroprotection. Br J Ophthalmol. 2003;87(12):1463-5.
    • (2003) Br J Ophthalmol , vol.87 , Issue.12 , pp. 1463-1465
    • Evans, D.W.1    Hosking, S.L.2    Gherghel, D.3    Barlett, J.D.4
  • 24
    • 14644435009 scopus 로고    scopus 로고
    • The Low-pressure Glaucoma Treatment Study (LoGTS) Study design and baseline characteristics of enrolled patients
    • Krupin T, Liebmann JM, Greenfield DS, Rosenberg LF, Ritch R et al. The Low-pressure Glaucoma Treatment Study (LoGTS) Study design and baseline characteristics of enrolled patients. Ophthalmology. 2005;112:376-85.
    • (2005) Ophthalmology , vol.112 , pp. 376-385
    • Krupin, T.1    Liebmann, J.M.2    Greenfield, D.S.3    Rosenberg, L.F.4    Ritch, R.5
  • 25
    • 34250669130 scopus 로고    scopus 로고
    • Special consideration in low tension glaucoma
    • Krupin T. Special consideration in low tension glaucoma. Can J Ophthalmol. 2007;42:414-7
    • (2007) Can J Ophthalmol , vol.42 , pp. 414-417
    • Krupin, T.1
  • 26
    • 77953448119 scopus 로고    scopus 로고
    • Market Share Data for Australia , from IMS June 2008.
    • Market Share Data for Australia , from IMS June 2008.
  • 27
    • 0032901575 scopus 로고    scopus 로고
    • For the Brimonidine Study Groups 1 and 2. Twice-daily brimonidine tartrate 0.2% vs timolol 0.5%: 1 year results in glaucoma patients
    • Katz LJ. For the Brimonidine Study Groups 1 and 2. Twice-daily brimonidine tartrate 0.2% vs timolol 0.5%: 1 year results in glaucoma patients. Am J Ophthalmol. 1999;127:20-6.
    • (1999) Am J Ophthalmol , vol.127 , pp. 20-26
    • Katz, L.J.1
  • 28
    • 0030877607 scopus 로고    scopus 로고
    • A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension. A controlled, randomized, multicenter clinical trial
    • Schuman JS, Horwitz B Choplin NT, et al. A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension. A controlled, randomized, multicenter clinical trial. Arch Ophthalmol. 1997;115:847-52.
    • (1997) Arch Ophthalmol , vol.115 , pp. 847-852
    • Schuman, J.S.1    Horwitz, B.2    Choplin, N.T.3
  • 29
    • 0031793877 scopus 로고    scopus 로고
    • LeBlanc RP; for the Brimonidine Study Group 2. Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol given twice daily in patients with glaucoma or ocular hypertension. Ophthalmology. 1998;105:1960-7.
    • LeBlanc RP; for the Brimonidine Study Group 2. Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol given twice daily in patients with glaucoma or ocular hypertension. Ophthalmology. 1998;105:1960-7.
  • 30
    • 0033965538 scopus 로고    scopus 로고
    • Melamed S, David R; for the Brionidine Study group 2. Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: three year results. Clin Ther. 2000;22:103-11.
    • Melamed S, David R; for the Brionidine Study group 2. Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: three year results. Clin Ther. 2000;22:103-11.
  • 31
    • 0034189105 scopus 로고    scopus 로고
    • The evolving pharmacotherapeutic profile of brimonidine, an alpha 2-adrenergic agonist, after for years of continuous use
    • Cantor LB. The evolving pharmacotherapeutic profile of brimonidine, an alpha 2-adrenergic agonist, after for years of continuous use. Exp Opin Pharmcother. 2000;1(4):815-34.
    • (2000) Exp Opin Pharmcother , vol.1 , Issue.4 , pp. 815-834
    • Cantor, L.B.1
  • 32
    • 0029043908 scopus 로고
    • Betaxlol eye drops. A clinical trial of safety and efficacy
    • Goldberg I, Goldberg H. Betaxlol eye drops. A clinical trial of safety and efficacy. Aust N Z J Ophthalmol. 1995;23:17-24.
    • (1995) Aust N Z J Ophthalmol , vol.23 , pp. 17-24
    • Goldberg, I.1    Goldberg, H.2
  • 33
    • 0029971304 scopus 로고    scopus 로고
    • The safety of topical beta-blockers in glaucoma treatment
    • Goldberg I. The safety of topical beta-blockers in glaucoma treatment. Med J. Aust 1996;164:49-49.
    • (1996) Med J. Aust , vol.164 , pp. 49-49
    • Goldberg, I.1
  • 34
    • 0034442185 scopus 로고    scopus 로고
    • For the Brimonidine Outcomes Study Group 2. Comparison of the clinical success rates and quality of life of brimonidine tartrate 0.2% and betaxolol 0.25% suspension in patients with open-angle glaucoma and ocular hypertension
    • Javitt J, Goldberg I. For the Brimonidine Outcomes Study Group 2. Comparison of the clinical success rates and quality of life of brimonidine tartrate 0.2% and betaxolol 0.25% suspension in patients with open-angle glaucoma and ocular hypertension. J Glaucoma. 2000;9:398-408.
    • (2000) J Glaucoma , vol.9 , pp. 398-408
    • Javitt, J.1    Goldberg, I.2
  • 35
    • 0029731441 scopus 로고    scopus 로고
    • A comparison of the safety and efficacy of twice daily brimonidine 0.2% versus Betaxolol 0.25% in subjects with elevated intraocular pressure
    • Serle JB. A comparison of the safety and efficacy of twice daily brimonidine 0.2% versus Betaxolol 0.25% in subjects with elevated intraocular pressure. Surv Ophthalmol. 1996;41(9 suppl 1):S39-47.
    • (1996) Surv Ophthalmol , vol.41 , Issue.9 SUPPL. 1
    • Serle, J.B.1
  • 36
    • 38349183905 scopus 로고    scopus 로고
    • The efficacy and harm of prostaglandin analogues for the IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: A systematic review
    • Hodge WG, Lachaine J, Steffensen I. et al. The efficacy and harm of prostaglandin analogues for the IOP reduction in glaucoma patients compared to dorzolamide and brimonidine: a systematic review. Br J Ophthalmol. 2008;92:7-12.
    • (2008) Br J Ophthalmol , vol.92 , pp. 7-12
    • Hodge, W.G.1    Lachaine, J.2    Steffensen, I.3
  • 37
    • 1642278078 scopus 로고    scopus 로고
    • Comparison of the safety and ef. cacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension
    • Whitson JT, Henry C, Hughes B, et al. Comparison of the safety and ef. cacy of dorzolamide 2% and brimonidine 0.2% in patients with glaucoma or ocular hypertension. J Glaucoma. 2004;13:168-73.
    • (2004) J Glaucoma , vol.13 , pp. 168-173
    • Whitson, J.T.1    Henry, C.2    Hughes, B.3
  • 38
    • 0033859558 scopus 로고    scopus 로고
    • Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocularpressure
    • Stewart WC, Sharpe ED, Harbin Jr TS, et al. Brimonidine 0.2% versus dorzolamide 2% each given three times daily to reduce intraocularpressure. Am J Opthalmol. 2001;29:723-7.
    • (2001) Am J Opthalmol , vol.29 , pp. 723-727
    • Stewart, W.C.1    Sharpe, E.D.2    Harbin Jr, T.S.3
  • 39
    • 3042828863 scopus 로고    scopus 로고
    • Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension
    • Sharpe ED, Day DG, Beischel CJ, et al. Brimonidine purite 0.15% versus dorzolamide 2% each given twice daily to reduce intraocular pressure in subjects with open angle glaucoma or ocular hypertension. Br J Ophthalmol. 2004;88:953-6.
    • (2004) Br J Ophthalmol , vol.88 , pp. 953-956
    • Sharpe, E.D.1    Day, D.G.2    Beischel, C.J.3
  • 40
    • 0035010973 scopus 로고    scopus 로고
    • Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension
    • Simmons ST. Efficacy of brimonidine 0.2% and dorzolamide 2% as adjunctive therapy to beta-blockers in adult patients with glaucoma or ocular hypertension. Clin Ther. 2001;23:604-19.
    • (2001) Clin Ther , vol.23 , pp. 604-619
    • Simmons, S.T.1
  • 41
    • 0034974257 scopus 로고    scopus 로고
    • Effectiveness and safety of brimonidine as adjunctive therapy for patients with elevated intraocular pressure in a large, open label community trial
    • Lee DA, Gornbein JA. Effectiveness and safety of brimonidine as adjunctive therapy for patients with elevated intraocular pressure in a large, open label community trial. J Glaucoma. 2001;10:220-6.
    • (2001) J Glaucoma , vol.10 , pp. 220-226
    • Lee, D.A.1    Gornbein, J.A.2
  • 42
    • 16244389661 scopus 로고    scopus 로고
    • 24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects
    • Konstas AG, Karabatsas CH, Lallos N, et al. 24-hour intraocular pressures with brimonidine purite versus dorzolamide added to latanoprost in primary open-angle glaucoma subjects. Ophthalmology. 2005;112:603-8.
    • (2005) Ophthalmology , vol.112 , pp. 603-608
    • Konstas, A.G.1    Karabatsas, C.H.2    Lallos, N.3
  • 43
    • 33748596339 scopus 로고    scopus 로고
    • Twice-daily 0.2% brimonidine-0.5% timolol . xed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: A 12-month randomized trial
    • Sherwood MB, Craven ER, Chou C et al. Twice-daily 0.2% brimonidine-0.5% timolol . xed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial. Arch Ophthlmol. 2006;124:1230-8.
    • (2006) Arch Ophthlmol , vol.124 , pp. 1230-1238
    • Sherwood, M.B.1    Craven, E.R.2    Chou, C.3
  • 44
    • 0034533062 scopus 로고    scopus 로고
    • A Comparison of dorzolamide-timolol combination versus the concomitant drugs
    • Choudri S, Wand M, Shields MB. A Comparison of dorzolamide-timolol combination versus the concomitant drugs. Am J Opthalmol. 200;130:832-3.
    • Am J Opthalmol , vol.200 , Issue.130 , pp. 832-833
    • Choudri, S.1    Wand, M.2    Shields, M.B.3
  • 45
    • 0025177329 scopus 로고
    • Systemic effects of medications used to treat glaucoma
    • Everitt DE, Avorn J. Systemic effects of medications used to treat glaucoma. Ann Int Med. 1990;112:120-5.
    • (1990) Ann Int Med , vol.112 , pp. 120-125
    • Everitt, D.E.1    Avorn, J.2
  • 46
    • 0034904822 scopus 로고    scopus 로고
    • Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25% suspension in patients with elevated intraocular pressure
    • For the Alphagan/Betaxolol Clinical Success Study Group
    • Cantor LB, Hoop J, Katz LJ, et al. For the Alphagan/Betaxolol Clinical Success Study Group. Comparison of the clinical success and quality-of-life impact of brimonidine 0.2% and betaxolol 0.25% suspension in patients with elevated intraocular pressure. Clin Ther. 2001;23(7):1032-9.
    • (2001) Clin Ther , vol.23 , Issue.7 , pp. 1032-1039
    • Cantor, L.B.1    Hoop, J.2    Katz, L.J.3
  • 47
    • 0031149150 scopus 로고    scopus 로고
    • Mechanisms of adrenergic agonist induced allergy:bioactivation and antigen formation
    • Thompson CD, MacDonald TL, Garst ME, et al. Mechanisms of adrenergic agonist induced allergy:bioactivation and antigen formation. Exp Eye Res. 1997;64(5):767-73.
    • (1997) Exp Eye Res , vol.64 , Issue.5 , pp. 767-773
    • Thompson, C.D.1    MacDonald, T.L.2    Garst, M.E.3
  • 48
    • 0000559384 scopus 로고    scopus 로고
    • A retrospective examination of drug-induced allergy to Alphagan and a proposal for a new reporting system
    • Abstract 2718
    • Abelson MB, Chapin M, Batoosingh A, et al. A retrospective examination of drug-induced allergy to Alphagan and a proposal for a new reporting system. Invest Opthalmol Vis Sci. 1999;40(4):S515. Abstract 2718.
    • (1999) Invest Opthalmol Vis Sci , vol.40 , Issue.4
    • Abelson, M.B.1    Chapin, M.2    Batoosingh, A.3
  • 49
    • 1642399896 scopus 로고    scopus 로고
    • Demographic and clinical factors associated with the development of alphagan induced allergy
    • Manni G, Centofanti M, Sacchetti M, et al. Demographic and clinical factors associated with the development of alphagan induced allergy. J Glaucoma. 2004;13(2):163-7.
    • (2004) J Glaucoma , vol.13 , Issue.2 , pp. 163-167
    • Manni, G.1    Centofanti, M.2    Sacchetti, M.3
  • 50
    • 0026516506 scopus 로고
    • Preservative-free artificial tear preparations. Assessment of corneal epithelial toxic effects
    • Berdy GJ, Abelson MB, Smith IM, George MA. Preservative-free artificial tear preparations. Assessment of corneal epithelial toxic effects. Arch Ophthalmol. 1992;110:528-32.
    • (1992) Arch Ophthalmol , vol.110 , pp. 528-532
    • Berdy, G.J.1    Abelson, M.B.2    Smith, I.M.3    George, M.A.4
  • 51
    • 0035200807 scopus 로고    scopus 로고
    • Effects of common ophthalmic preservatives on ocular health
    • Noecker R. Effects of common ophthalmic preservatives on ocular health. Adv Ther. 2001;18:5.
    • (2001) Adv Ther , vol.18 , pp. 5
    • Noecker, R.1
  • 52
    • 0036220303 scopus 로고    scopus 로고
    • Twelve-month evaluation of brimonidine-purite versus brimonidine in patients with glaucoma or ocular hypertension
    • Katz LJ. Twelve-month evaluation of brimonidine-purite versus brimonidine in patients with glaucoma or ocular hypertension. J Glaucoma. 2002;11:119-26.
    • (2002) J Glaucoma , vol.11 , pp. 119-126
    • Katz, L.J.1
  • 53
    • 0037327848 scopus 로고    scopus 로고
    • A 3 month comparison of efficacy and safety of brimonidine-purite 0.15% and brimonidine 0.2% in patients with glaucoma or ocular hypertension
    • Mundorf T, Williams R, Whitcup S et al. A 3 month comparison of efficacy and safety of brimonidine-purite 0.15% and brimonidine 0.2% in patients with glaucoma or ocular hypertension. J Ocular Pharmacol Ther. 2003;19:1.
    • (2003) J Ocular Pharmacol Ther , vol.19 , pp. 1
    • Mundorf, T.1    Williams, R.2    Whitcup, S.3
  • 54
    • 0035487977 scopus 로고    scopus 로고
    • Safety and ef. cacy of brimonidine in children with glaucoma
    • Enyedi LB, Freedman SF. Safety and ef. cacy of brimonidine in children with glaucoma. J AAPOS. 2002;5(5):281-4.
    • (2002) J AAPOS , vol.5 , Issue.5 , pp. 281-284
    • Enyedi, L.B.1    Freedman, S.F.2
  • 55
    • 0141928070 scopus 로고    scopus 로고
    • Compliance barriers in glaucoma: A systematic classi. cation
    • Tsai JC, McClure CA, Ramos SE et al. Compliance barriers in glaucoma: A systematic classi. cation. J Glaucoma. 2003;12:393-8.
    • (2003) J Glaucoma , vol.12 , pp. 393-398
    • Tsai, J.C.1    McClure, C.A.2    Ramos, S.E.3
  • 56
    • 26844475953 scopus 로고    scopus 로고
    • Persistence and adherence with topical glaucoma therapy
    • Nordstrom BL, Friedman DS, Mozaffari E et al. Persistence and adherence with topical glaucoma therapy. Am J Ophthalmol. 2005;140:598-606.
    • (2005) Am J Ophthalmol , vol.140 , pp. 598-606
    • Nordstrom, B.L.1    Friedman, D.S.2    Mozaffari, E.3
  • 57
    • 53349109120 scopus 로고    scopus 로고
    • Comparison of allergy rates in glaucoma patients receiving brimonidine 0.2% monotherapy versus fixed-combination brimonidine 0.2%-timolol 0.5% therapy
    • Aug 6, Epub ahead of print
    • Motolko MA. Comparison of allergy rates in glaucoma patients receiving brimonidine 0.2% monotherapy versus fixed-combination brimonidine 0.2%-timolol 0.5% therapy. Curr Med Res Opin. 2008 Aug 6. [Epub ahead of print]
    • (2008) Curr Med Res Opin
    • Motolko, M.A.1
  • 58
    • 35848945084 scopus 로고    scopus 로고
    • Ocular Comfort of Combination Glaucoma Therapies:Brimonidine 0.2%/Timolol 0.5% Compared with Dorzolamide2%/Timolol 0.5%
    • Chan K, Testa M, McCluskey P. Ocular Comfort of Combination Glaucoma Therapies:Brimonidine 0.2%/Timolol 0.5% Compared with Dorzolamide2%/Timolol 0.5%. J Ocul Pharmacol Ther. 2007;32(4):372-6.
    • (2007) J Ocul Pharmacol Ther , vol.32 , Issue.4 , pp. 372-376
    • Chan, K.1    Testa, M.2    McCluskey, P.3
  • 59
    • 14644417266 scopus 로고    scopus 로고
    • Alphagan allergy may increase the propensity for multiple eye-drop allergy
    • Osborne SA, Montgomery DM, Morris D, McKay IC. Alphagan allergy may increase the propensity for multiple eye-drop allergy. Eye. 2005;19:129-37.
    • (2005) Eye , vol.19 , pp. 129-137
    • Osborne, S.A.1    Montgomery, D.M.2    Morris, D.3    McKay, I.C.4
  • 60
    • 34248564890 scopus 로고    scopus 로고
    • Reduced ocular allergy with fixed-combination 0.2% brimonidine- 0.5% timolol
    • Alvaroado JA. Reduced ocular allergy with fixed-combination 0.2% brimonidine- 0.5% timolol. Arch Ophthalmol. 2007;125:717.
    • (2007) Arch Ophthalmol , vol.125 , pp. 717
    • Alvaroado, J.A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.