-
1
-
-
50249180215
-
Bile acids: Chemistry, pathochemistry, biology, pathobiology, and therapeutics
-
Hofmann, A. F., and L. R. Hagey. 2008. Bile acids: chemistry, pathochemistry, biology, pathobiology, and therapeutics. Cell. Mol. Life Sci. 65: 2461-2483.
-
(2008)
Cell. Mol. Life Sci
, vol.65
, pp. 2461-2483
-
-
Hofmann, A.F.1
Hagey, L.R.2
-
2
-
-
34548572892
-
Bile acid transporters: Structure, function, regulation and pathophysiological implications
-
Alrefai, W. A., and R. K. Gill. 2007. Bile acid transporters: structure, function, regulation and pathophysiological implications. Pharm. Res. 24: 1803-1823.
-
(2007)
Pharm. Res
, vol.24
, pp. 1803-1823
-
-
Alrefai, W.A.1
Gill, R.K.2
-
3
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
Trauner, M., and J. L. Boyer. 2003. Bile salt transporters: molecular characterization, function, and regulation. Physiol. Rev. 83: 633-671.
-
(2003)
Physiol. Rev
, vol.83
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
4
-
-
70349430938
-
Bile acids: Regulation of synthesis
-
Chiang, J. Y. 2009. Bile acids: regulation of synthesis. J Lipid Res. 50: 1955-1966
-
(2009)
J Lipid Res
, vol.50
, pp. 1955-1966
-
-
Chiang, J.Y.1
-
5
-
-
48749113401
-
Targeting bile-acid signalling for metabolic diseases
-
Thomas, C., R. Pellicciari, M. Pruzanski, J. Auwerx, and K. Schoonjans. 2008. Targeting bile-acid signalling for metabolic diseases. Nat. Rev. Drug Discov. 7: 678-693.
-
(2008)
Nat. Rev. Drug Discov
, vol.7
, pp. 678-693
-
-
Thomas, C.1
Pellicciari, R.2
Pruzanski, M.3
Auwerx, J.4
Schoonjans, K.5
-
6
-
-
69449095892
-
Bile acids as regulatory molecules
-
Hylemon, P. B., H. Zhou, W. M. Pandak, S. Ren, G. Gil, and P. Dent. 2009. Bile acids as regulatory molecules. J Lipid Res. 50: 1509-1520
-
(2009)
J Lipid Res
, vol.50
, pp. 1509-1520
-
-
Hylemon, P.B.1
Zhou, H.2
Pandak, W.M.3
Ren, S.4
Gil, G.5
Dent, P.6
-
7
-
-
58249110568
-
Role of bile acids and bile acid receptors in metabolic regulation
-
Lefebvre, P., B. Cariou, F. Lien, F. Kuipers, and B. Staels. 2009. Role of bile acids and bile acid receptors in metabolic regulation. Physiol. Rev. 89: 147-191.
-
(2009)
Physiol. Rev
, vol.89
, pp. 147-191
-
-
Lefebvre, P.1
Cariou, B.2
Lien, F.3
Kuipers, F.4
Staels, B.5
-
8
-
-
33947134611
-
Bile formation and the enterohepatic circulation
-
L. R. Johnson, editor. Elsevier Academic Press, Amsterdam. Chapter 56
-
Dawson, P. A. Shneider. B. L., Hofmann A.F. 2006. Bile formation and the enterohepatic circulation. In Physiology of the Gastrointestinal Tract. L. R. Johnson, editor. Elsevier Academic Press, Amsterdam. Chapter 56: 1437-1462.
-
(2006)
Physiology of the Gastrointestinal Tract
, pp. 1437-1462
-
-
Dawson, P.A.1
Shneider, B.L.2
Hofmann, A.F.3
-
9
-
-
0014289540
-
Mechanisms for the intestinal absorption of bile acids
-
Dietschy, J. M. 1968. Mechanisms for the intestinal absorption of bile acids. J. Lipid Res. 9: 297-309.
-
(1968)
J. Lipid Res
, vol.9
, pp. 297-309
-
-
Dietschy, J.M.1
-
10
-
-
0016254128
-
Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum
-
Krag, E., and S. F. Phillips. 1974. Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum. J. Clin. Invest. 53: 1686-1694.
-
(1974)
J. Clin. Invest
, vol.53
, pp. 1686-1694
-
-
Krag, E.1
Phillips, S.F.2
-
11
-
-
0015351260
-
Characterization of the kinetics of the passive and active transport mechanisms for bile acid absorption in the small intestine and colon of the rat
-
Schiff, E. R., N. C. Small, and J. M. Dietschy. 1972. Characterization of the kinetics of the passive and active transport mechanisms for bile acid absorption in the small intestine and colon of the rat. J. Clin. Invest. 51: 1351-1362.
-
(1972)
J. Clin. Invest
, vol.51
, pp. 1351-1362
-
-
Schiff, E.R.1
Small, N.C.2
Dietschy, J.M.3
-
12
-
-
0035204295
-
Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: Application to rodents and humans
-
Hulzebos, C. V., L. Renfurm, R. H. Bandsma, H. J. Verkade, T. Boer, R. Boverhof, H. Tanaka, I. Mierau, P. J. Sauer, F. Kuipers, et al. 2001. Measurement of parameters of cholic acid kinetics in plasma using a microscale stable isotope dilution technique: application to rodents and humans. J. Lipid Res. 42: 1923-1929.
-
(2001)
J. Lipid Res
, vol.42
, pp. 1923-1929
-
-
Hulzebos, C.V.1
Renfurm, L.2
Bandsma, R.H.3
Verkade, H.J.4
Boer, T.5
Boverhof, R.6
Tanaka, H.7
Mierau, I.8
Sauer, P.J.9
Kuipers, F.10
-
13
-
-
0020679384
-
Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man
-
Hofmann, A. F., G. Molino, M. Milanese, and G. Belforte. 1983. Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man. J. Clin. Invest. 71: 1003-1022.
-
(1983)
J. Clin. Invest
, vol.71
, pp. 1003-1022
-
-
Hofmann, A.F.1
Molino, G.2
Milanese, M.3
Belforte, G.4
-
14
-
-
0027501003
-
Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans
-
Dietschy, J. M., S. D. Turley, and D. K. Spady. 1993. Role of liver in the maintenance of cholesterol and low density lipoprotein homeostasis in different animal species, including humans. J. Lipid Res. 34: 1637-1659.
-
(1993)
J. Lipid Res
, vol.34
, pp. 1637-1659
-
-
Dietschy, J.M.1
Turley, S.D.2
Spady, D.K.3
-
15
-
-
0037040184
-
Control of cholesterol turnover in the mouse
-
Dietschy, J. M., and S. D. Turley. 2002. Control of cholesterol turnover in the mouse. J. Biol. Chem. 277: 3801-3804.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 3801-3804
-
-
Dietschy, J.M.1
Turley, S.D.2
-
16
-
-
0025766414
-
Biological and medical aspects of active ileal transport of bile acids
-
Hofmann, A. F., C. D. Schteingart, and J. Lillienau. 1991. Biological and medical aspects of active ileal transport of bile acids. Ann. Med. 23: 169-175.
-
(1991)
Ann. Med
, vol.23
, pp. 169-175
-
-
Hofmann, A.F.1
Schteingart, C.D.2
Lillienau, J.3
-
17
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
Kullak-Ublick, G. A., B. Stieger, and P. J. Meier. 2004. Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology. 126: 322-342.
-
(2004)
Gastroenterology
, vol.126
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Meier, P.J.3
-
18
-
-
0028153313
-
Free concentrations of intracellular fl uorescent anions determined by cytoplasmic dialysis of isolated hepatocytes
-
Weinman, S. A., and L. M. Maglova. 1994. Free concentrations of intracellular fl uorescent anions determined by cytoplasmic dialysis of isolated hepatocytes. Am. J. Physiol. 267: G922-G931.
-
(1994)
Am. J. Physiol
, vol.267
-
-
Weinman, S.A.1
Maglova, L.M.2
-
19
-
-
0027405329
-
Hepatic taurocholate uptake is electrogenic and infl uenced by transmembrane potential difference
-
Lidofsky, S. D., J. G. Fitz, R. A. Weisiger, and B. F. Scharschmidt. 1993. Hepatic taurocholate uptake is electrogenic and infl uenced by transmembrane potential difference. Am. J. Physiol. 264: G478-G485.
-
(1993)
Am. J. Physiol
, vol.264
-
-
Lidofsky, S.D.1
Fitz, J.G.2
Weisiger, R.A.3
Scharschmidt, B.F.4
-
20
-
-
0017092068
-
Uptake of bile acids by perfused rat liver
-
Reichen, J., and G. Paumgartner. 1976. Uptake of bile acids by perfused rat liver. Am. J. Physiol. 231: 734-742.
-
(1976)
Am. J. Physiol
, vol.231
, pp. 734-742
-
-
Reichen, J.1
Paumgartner, G.2
-
22
-
-
0032422456
-
Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes
-
Kouzuki, H., H. Suzuki, K. Ito, R. Ohashi, and Y. Sugiyama. 1998. Contribution of sodium taurocholate co-transporting polypeptide to the uptake of its possible substrates into rat hepatocytes. J. Pharmacol. Exp. Ther. 286: 1043-1050.
-
(1998)
J. Pharmacol. Exp. Ther
, vol.286
, pp. 1043-1050
-
-
Kouzuki, H.1
Suzuki, H.2
Ito, K.3
Ohashi, R.4
Sugiyama, Y.5
-
23
-
-
0026529394
-
ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles
-
Stieger, B., B. O'Neill, and P. J. Meier. 1992. ATP-dependent bile-salt transport in canalicular rat liver plasma-membrane vesicles. Biochem. J. 284: 67-74.
-
(1992)
Biochem. J
, vol.284
, pp. 67-74
-
-
Stieger, B.1
O'Neill, B.2
Meier, P.J.3
-
25
-
-
0035831094
-
Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump
-
Akita, H., H. Suzuki, K. Ito, S. Kinoshita, N. Sato, H. Takikawa, and Y. Sugiyama. 2001. Characterization of bile acid transport mediated by multidrug resistance associated protein 2 and bile salt export pump. Biochim. Biophys. Acta. 1511: 7-16.
-
(2001)
Biochim. Biophys. Acta
, vol.1511
, pp. 7-16
-
-
Akita, H.1
Suzuki, H.2
Ito, K.3
Kinoshita, S.4
Sato, N.5
Takikawa, H.6
Sugiyama, Y.7
-
26
-
-
33846706434
-
The apical conjugate efflux pump ABCC2 (MRP2)
-
Nies, A. T., and D. Keppler. 2007. The apical conjugate efflux pump ABCC2 (MRP2). Pflugers Arch. 453: 643-659.
-
(2007)
Pflugers Arch
, vol.453
, pp. 643-659
-
-
Nies, A.T.1
Keppler, D.2
-
27
-
-
24944483081
-
Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice
-
Lam, P., R. Wang, and V. Ling. 2005. Bile acid transport in sister of P-glycoprotein (ABCB11) knockout mice. Biochemistry. 44: 12598-12605.
-
(2005)
Biochemistry
, vol.44
, pp. 12598-12605
-
-
Lam, P.1
Wang, R.2
Ling, V.3
-
28
-
-
33745774784
-
Role of nuclear receptors in the adaptive response to bile acids and cholestasis: Pathogenetic and therapeutic considerations
-
Zollner, G., H. U. Marschall, M. Wagner, and M. Trauner. 2006. Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations. Mol. Pharm. 3: 231-251.
-
(2006)
Mol. Pharm
, vol.3
, pp. 231-251
-
-
Zollner, G.1
Marschall, H.U.2
Wagner, M.3
Trauner, M.4
-
29
-
-
0035080391
-
Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver
-
Soroka, C. J., J. M. Lee, F. Azzaroli, and J. L. Boyer. 2001. Cellular localization and up-regulation of multidrug resistance-associated protein 3 in hepatocytes and cholangiocytes during obstructive cholestasis in rat liver. Hepatology. 33: 783-791.
-
(2001)
Hepatology
, vol.33
, pp. 783-791
-
-
Soroka, C.J.1
Lee, J.M.2
Azzaroli, F.3
Boyer, J.L.4
-
30
-
-
0034723163
-
ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3)
-
Hirohashi, T., H. Suzuki, H. Takikawa, and Y. Sugiyama. 2000. ATP-dependent transport of bile salts by rat multidrug resistance-associated protein 3 (Mrp3). J. Biol. Chem. 275: 2905-2910.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 2905-2910
-
-
Hirohashi, T.1
Suzuki, H.2
Takikawa, H.3
Sugiyama, Y.4
-
31
-
-
2542440464
-
Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice
-
Assem, M., E. G. Schuetz, M. Leggas, D. Sun, K. Yasuda, G. Reid, N. Zelcer, M. Adachi, S. Strom, R. M. Evans, et al. 2004. Interactions between hepatic Mrp4 and Sult2a as revealed by the constitutive androstane receptor and Mrp4 knockout mice. J. Biol. Chem. 279: 22250-22257.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 22250-22257
-
-
Assem, M.1
Schuetz, E.G.2
Leggas, M.3
Sun, D.4
Yasuda, K.5
Reid, G.6
Zelcer, N.7
Adachi, M.8
Strom, S.9
Evans, R.M.10
-
32
-
-
65449177586
-
High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis
-
Schaap, F. G., N. A. van der Gaag, D. J. Gouma, and P. L. Jansen. 2009. High expression of the bile salt-homeostatic hormone fibroblast growth factor 19 in the liver of patients with extrahepatic cholestasis. Hepatology. 49: 1228-1235.
-
(2009)
Hepatology
, vol.49
, pp. 1228-1235
-
-
Schaap, F.G.1
van der Gaag, N.A.2
Gouma, D.J.3
Jansen, P.L.4
-
33
-
-
33646871585
-
Upregulation of a basolateral FXR-dependent bile acid effl ux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents
-
Boyer, J. L., M. Trauner, A. Mennone, C. J. Soroka, S. Y. Cai, T. Moustafa, G. Zollner, J. Y. Lee, and N. Ballatori. 2006. Upregulation of a basolateral FXR-dependent bile acid effl ux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G1124-G1130.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Boyer, J.L.1
Trauner, M.2
Mennone, A.3
Soroka, C.J.4
Cai, S.Y.5
Moustafa, T.6
Zollner, G.7
Lee, J.Y.8
Ballatori, N.9
-
34
-
-
0042766881
-
Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane
-
Rius, M., A. T. Nies, J. Hummel-Eisenbeiss, G. Jedlitschky, and D. Keppler. 2003. Cotransport of reduced glutathione with bile salts by MRP4 (ABCC4) localized to the basolateral hepatocyte membrane. Hepatology. 38: 374-384.
-
(2003)
Hepatology
, vol.38
, pp. 374-384
-
-
Rius, M.1
Nies, A.T.2
Hummel-Eisenbeiss, J.3
Jedlitschky, G.4
Keppler, D.5
-
36
-
-
23244465392
-
Complementary stimulation of hepatobiliary transport and detoxifi cation systems by rifampicin and ursodeoxycholic acid in humans
-
Marschall, H. U., M. Wagner, G. Zollner, P. Fickert, U. Diczfalusy, J. Gumhold, D. Silbert, A. Fuchsbichler, L. Benthin, R. Grundstrom, et al. 2005. Complementary stimulation of hepatobiliary transport and detoxifi cation systems by rifampicin and ursodeoxycholic acid in humans. Gastroenterology. 129: 476-485.
-
(2005)
Gastroenterology
, vol.129
, pp. 476-485
-
-
Marschall, H.U.1
Wagner, M.2
Zollner, G.3
Fickert, P.4
Diczfalusy, U.5
Gumhold, J.6
Silbert, D.7
Fuchsbichler, A.8
Benthin, L.9
Grundstrom, R.10
-
37
-
-
0034802573
-
Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver
-
Akita, H., H. Suzuki, and Y. Sugiyama. 2001. Sinusoidal efflux of taurocholate is enhanced in Mrp2-deficient rat liver. Pharm. Res. 18: 1119-1125.
-
(2001)
Pharm. Res
, vol.18
, pp. 1119-1125
-
-
Akita, H.1
Suzuki, H.2
Sugiyama, Y.3
-
38
-
-
15444373825
-
Molecular regulation of hepatobiliary transport systems: Clinical implications for understanding and treating cholestasis
-
Trauner, M., M. Wagner, P. Fickert, and G. Zollner. 2005. Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis. J. Clin. Gastroenterol. 39: S111-S124.
-
(2005)
J. Clin. Gastroenterol
, vol.39
-
-
Trauner, M.1
Wagner, M.2
Fickert, P.3
Zollner, G.4
-
39
-
-
34547870567
-
Expression of bile acid synthesis and detoxifi cation enzymes and the alternative bile acid effl ux pump MRP4 in patients with primary biliary cirrhosis
-
Zollner, G., M. Wagner, P. Fickert, D. Silbert, J. Gumhold, K. Zatloukal, H. Denk, and M. Trauner. 2007. Expression of bile acid synthesis and detoxifi cation enzymes and the alternative bile acid effl ux pump MRP4 in patients with primary biliary cirrhosis. Liver Int. 27: 920-929.
-
(2007)
Liver Int
, vol.27
, pp. 920-929
-
-
Zollner, G.1
Wagner, M.2
Fickert, P.3
Silbert, D.4
Gumhold, J.5
Zatloukal, K.6
Denk, H.7
Trauner, M.8
-
40
-
-
34249747403
-
Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis
-
Teng, S., and M. Piquette-Miller. 2007. Hepatoprotective role of PXR activation and MRP3 in cholic acid-induced cholestasis. Br. J. Pharmacol. 151: 367-376.
-
(2007)
Br. J. Pharmacol
, vol.151
, pp. 367-376
-
-
Teng, S.1
Piquette-Miller, M.2
-
41
-
-
23344432870
-
Nuclear receptor ligands: Rational and effective therapy for chronic cholestatic liver disease?
-
Boyer, J. L. 2005. Nuclear receptor ligands: rational and effective therapy for chronic cholestatic liver disease? Gastroenterology. 129: 735-740.
-
(2005)
Gastroenterology
, vol.129
, pp. 735-740
-
-
Boyer, J.L.1
-
42
-
-
33646541411
-
Mrp4 -/- mice have an impaired cytoprotective response in obstructive cholestasis
-
Mennone, A., C. J. Soroka, S. Y. Cai, K. Harry, M. Adachi, L. Hagey, J. D. Schuetz, and J. L. Boyer. 2006. Mrp4 -/- mice have an impaired cytoprotective response in obstructive cholestasis. Hepatology. 43: 1013-1021.
-
(2006)
Hepatology
, vol.43
, pp. 1013-1021
-
-
Mennone, A.1
Soroka, C.J.2
Cai, S.Y.3
Harry, K.4
Adachi, M.5
Hagey, L.6
Schuetz, J.D.7
Boyer, J.L.8
-
43
-
-
1242317691
-
The sodium bile salt cotransport family SLC10
-
Hagenbuch, B., and P. Dawson. 2004. The sodium bile salt cotransport family SLC10. Pflugers Arch. 447: 566-570.
-
(2004)
Pflugers Arch
, vol.447
, pp. 566-570
-
-
Hagenbuch, B.1
Dawson, P.2
-
44
-
-
33645119837
-
The solute carrier family SLC10: More than a family of bile acid transporters regarding function and phylogenetic relationships
-
Geyer, J., T. Wilke, and E. Petzinger. 2006. The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships. Naunyn Schmiedebergs Arch. Pharmacol. 372: 413-431.
-
(2006)
Naunyn Schmiedebergs Arch. Pharmacol
, vol.372
, pp. 413-431
-
-
Geyer, J.1
Wilke, T.2
Petzinger, E.3
-
45
-
-
34547096264
-
Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria
-
Godoy, J. R., C. Fernandes, B. Doring, K. Beuerlein, E. Petzinger, and J. Geyer. 2007. Molecular and phylogenetic characterization of a novel putative membrane transporter (SLC10A7), conserved in vertebrates and bacteria. Eur. J. Cell Biol. 86: 445-460.
-
(2007)
Eur. J. Cell Biol
, vol.86
, pp. 445-460
-
-
Godoy, J.R.1
Fernandes, C.2
Doring, B.3
Beuerlein, K.4
Petzinger, E.5
Geyer, J.6
-
46
-
-
0029893370
-
Sinusoidal (basolateral) bile salt uptake systems of hepatocytes
-
Hagenbuch, B., and P. J. Meier. 1996. Sinusoidal (basolateral) bile salt uptake systems of hepatocytes. Semin. Liver Dis. 16: 129-136.
-
(1996)
Semin. Liver Dis
, vol.16
, pp. 129-136
-
-
Hagenbuch, B.1
Meier, P.J.2
-
47
-
-
0031392308
-
Electrogenicity of Na(+)-coupled bile acid transporters
-
Weinman, S. A. 1997. Electrogenicity of Na(+)-coupled bile acid transporters. Yale J. Biol. Med. 70: 331-340.
-
(1997)
Yale J. Biol. Med
, vol.70
, pp. 331-340
-
-
Weinman, S.A.1
-
48
-
-
0028294173
-
Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells
-
Boyer, J. L., O. C. Ng, M. Ananthanarayanan, A. F. Hofmann, C. D. Schteingart, B. Hagenbuch, B. Stieger, and P. J. Meier. 1994. Expression and characterization of a functional rat liver Na+ bile acid cotransport system in COS-7 cells. Am. J. Physiol. 266: G382-G387.
-
(1994)
Am. J. Physiol
, vol.266
-
-
Boyer, J.L.1
Ng, O.C.2
Ananthanarayanan, M.3
Hofmann, A.F.4
Schteingart, C.D.5
Hagenbuch, B.6
Stieger, B.7
Meier, P.J.8
-
49
-
-
0028231206
-
Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter
-
Hagenbuch, B., and P. J. Meier. 1994. Molecular cloning, chromosomal localization, and functional characterization of a human liver Na+/bile acid cotransporter. J. Clin. Invest. 93: 1326-1331.
-
(1994)
J. Clin. Invest
, vol.93
, pp. 1326-1331
-
-
Hagenbuch, B.1
Meier, P.J.2
-
50
-
-
0142151027
-
Substrate specifi cities of rat oatp1 and ntcp: Implications for hepatic organic anion uptake
-
Hata, S., P. Wang, N. Eftychiou, M. Ananthanarayanan, A. Batta, G. Salen, K. S. Pang, and A. W. Wolkoff. 2003. Substrate specifi cities of rat oatp1 and ntcp: implications for hepatic organic anion uptake. Am. J. Physiol. Gastrointest. Liver Physiol. 285: G829-G839.
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.285
-
-
Hata, S.1
Wang, P.2
Eftychiou, N.3
Ananthanarayanan, M.4
Batta, A.5
Salen, G.6
Pang, K.S.7
Wolkoff, A.W.8
-
51
-
-
0032822957
-
Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters
-
Kramer, W., S. Stengelin, K. H. Baringhaus, A. Enhsen, H. Heuer, W. Becker, D. Corsiero, F. Girbig, R. Noll, and C. Weyland. 1999. Substrate specificity of the ileal and the hepatic Na(+)/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters. J. Lipid Res. 40: 1604-1617.
-
(1999)
J. Lipid Res
, vol.40
, pp. 1604-1617
-
-
Kramer, W.1
Stengelin, S.2
Baringhaus, K.H.3
Enhsen, A.4
Heuer, H.5
Becker, W.6
Corsiero, D.7
Girbig, F.8
Noll, R.9
Weyland, C.10
-
52
-
-
0030000768
-
Functional characterization of the hepatic sodium-dependent taurocholate transporter stably transfected into an immortalized liver-derived cell line and V79 fibroblasts
-
Platte, H. D., W. Honscha, K. Schuh, and E. Petzinger. 1996. Functional characterization of the hepatic sodium-dependent taurocholate transporter stably transfected into an immortalized liver-derived cell line and V79 fibroblasts. Eur. J. Cell Biol. 70: 54-60.
-
(1996)
Eur. J. Cell Biol
, vol.70
, pp. 54-60
-
-
Platte, H.D.1
Honscha, W.2
Schuh, K.3
Petzinger, E.4
-
53
-
-
10844270655
-
Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump
-
Mita, S., H. Suzuki, H. Akita, B. Stieger, P. J. Meier, A. F. Hofmann, and Y. Sugiyama. 2005. Vectorial transport of bile salts across MDCK cells expressing both rat Na+-taurocholate cotransporting polypeptide and rat bile salt export pump. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G159-G167.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
-
-
Mita, S.1
Suzuki, H.2
Akita, H.3
Stieger, B.4
Meier, P.J.5
Hofmann, A.F.6
Sugiyama, Y.7
-
54
-
-
33644980997
-
Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep
-
Mita, S., H. Suzuki, H. Akita, H. Hayashi, R. Onuki, A. F. Hofmann, and Y. Sugiyama. 2006. Vectorial transport of unconjugated and conjugated bile salts by monolayers of LLC-PK1 cells doubly transfected with human NTCP and BSEP or with rat Ntcp and Bsep. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G550-G556.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Mita, S.1
Suzuki, H.2
Akita, H.3
Hayashi, H.4
Onuki, R.5
Hofmann, A.F.6
Sugiyama, Y.7
-
55
-
-
0031916146
-
Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter
-
Craddock, A. L., M. W. Love, R. W. Daniel, L. C. Kirby, H. C. Walters, M. H. Wong, and P. A. Dawson. 1998. Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter. Am. J. Physiol. 274: G157-G169.
-
(1998)
Am. J. Physiol
, vol.274
-
-
Craddock, A.L.1
Love, M.W.2
Daniel, R.W.3
Kirby, L.C.4
Walters, H.C.5
Wong, M.H.6
Dawson, P.A.7
-
56
-
-
0036238779
-
Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2
-
Meng, L. J., P. Wang, A. W. Wolkoff, R. B. Kim, R. G. Tirona, A. F. Hofmann, and K. S. Pang. 2002. Transport of the sulfated, amidated bile acid, sulfolithocholyltaurine, into rat hepatocytes is mediated by Oatp1 and Oatp2. Hepatology. 35: 1031-1040.
-
(2002)
Hepatology
, vol.35
, pp. 1031-1040
-
-
Meng, L.J.1
Wang, P.2
Wolkoff, A.W.3
Kim, R.B.4
Tirona, R.G.5
Hofmann, A.F.6
Pang, K.S.7
-
57
-
-
0030725999
-
Substrate specifi city of sinusoidal bile acid and organic anion uptake systems in rat and human liver
-
Meier, P. J., U. Eckhardt, A. Schroeder, B. Hagenbuch, and B. Stieger. 1997. Substrate specifi city of sinusoidal bile acid and organic anion uptake systems in rat and human liver. Hepatology. 26: 1667-1677.
-
(1997)
Hepatology
, vol.26
, pp. 1667-1677
-
-
Meier, P.J.1
Eckhardt, U.2
Schroeder, A.3
Hagenbuch, B.4
Stieger, B.5
-
58
-
-
0032732615
-
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity
-
Kim, R. B., B. Leake, M. Cvetkovic, M. M. Roden, J. Nadeau, A. Walubo, and G. R. Wilkinson. 1999. Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. J. Pharmacol. Exp. Ther. 291: 1204-1209.
-
(1999)
J. Pharmacol. Exp. Ther
, vol.291
, pp. 1204-1209
-
-
Kim, R.B.1
Leake, B.2
Cvetkovic, M.3
Roden, M.M.4
Nadeau, J.5
Walubo, A.6
Wilkinson, G.R.7
-
59
-
-
33747838057
-
Inhibition of bile acid transport across Na+/ taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs
-
Mita, S., H. Suzuki, H. Akita, H. Hayashi, R. Onuki, A. F. Hofmann, and Y. Sugiyama. 2006. Inhibition of bile acid transport across Na+/ taurocholate cotransporting polypeptide (SLC10A1) and bile salt export pump (ABCB 11)-coexpressing LLC-PK1 cells by cholestasis-inducing drugs. Drug Metab. Dispos. 34: 1575-1581.
-
(2006)
Drug Metab. Dispos
, vol.34
, pp. 1575-1581
-
-
Mita, S.1
Suzuki, H.2
Akita, H.3
Hayashi, H.4
Onuki, R.5
Hofmann, A.F.6
Sugiyama, Y.7
-
60
-
-
34248562942
-
Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: A mechanism for species differences in hepatotoxicity
-
Leslie, E. M., P. B. Watkins, R. B. Kim, and K. L. Brouwer. 2007. Differential inhibition of rat and human Na+-dependent taurocholate cotransporting polypeptide (NTCP/SLC10A1)by bosentan: a mechanism for species differences in hepatotoxicity. J. Pharmacol. Exp. Ther. 321: 1170-1178.
-
(2007)
J. Pharmacol. Exp. Ther
, vol.321
, pp. 1170-1178
-
-
Leslie, E.M.1
Watkins, P.B.2
Kim, R.B.3
Brouwer, K.L.4
-
61
-
-
0027397796
-
Phylogenic and ontogenic expression of hepatocellular bile acid transport
-
Boyer, J. L., B. Hagenbuch, M. Ananthanarayanan, F. Suchy, B. Stieger, and P. J. Meier. 1993. Phylogenic and ontogenic expression of hepatocellular bile acid transport. Proc. Natl. Acad. Sci. USA. 90: 435-438.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 435-438
-
-
Boyer, J.L.1
Hagenbuch, B.2
Ananthanarayanan, M.3
Suchy, F.4
Stieger, B.5
Meier, P.J.6
-
62
-
-
0029822980
-
Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes
-
Hagenbuch, B., B. F. Scharschmidt, and P. J. Meier. 1996. Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes. Biochem. J. 316: 901-904.
-
(1996)
Biochem. J
, vol.316
, pp. 901-904
-
-
Hagenbuch, B.1
Scharschmidt, B.F.2
Meier, P.J.3
-
63
-
-
0027410816
-
Na(+)- dependent bile acid transport by hepatocytes is mediated by a protein similar to microsomal epoxide hydrolase
-
Von Dippe, P., M. Amoui, C. Alves, and D. Levy. 1993. Na(+)- dependent bile acid transport by hepatocytes is mediated by a protein similar to microsomal epoxide hydrolase. Am. J. Physiol. 264: G528-G534.
-
(1993)
Am. J. Physiol
, vol.264
-
-
Von Dippe, P.1
Amoui, M.2
Alves, C.3
Levy, D.4
-
64
-
-
1342304081
-
Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition
-
Ho, R. H., B. F. Leake, R. L. Roberts, W. Lee, and R. B. Kim. 2004. Ethnicity-dependent polymorphism in Na+-taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition. J. Biol. Chem. 279: 7213-7222.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 7213-7222
-
-
Ho, R.H.1
Leake, B.F.2
Roberts, R.L.3
Lee, W.4
Kim, R.B.5
-
65
-
-
0037994064
-
Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT
-
Carlton, V. E., B. Z. Harris, E. G. Puffenberger, A. K. Batta, A. S. Knisely, D. L. Robinson, K. A. Strauss, B. L. Shneider, W. A. Lim, G. Salen, et al. 2003. Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT. Nat. Genet. 34: 91-96.
-
(2003)
Nat. Genet
, vol.34
, pp. 91-96
-
-
Carlton, V.E.1
Harris, B.Z.2
Puffenberger, E.G.3
Batta, A.K.4
Knisely, A.S.5
Robinson, D.L.6
Strauss, K.A.7
Shneider, B.L.8
Lim, W.A.9
Salen, G.10
-
66
-
-
7644230747
-
Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: A tight junction disease
-
Hadj-Rabia, S., L. Baala, P. Vabres, D. Hamel-Teillac, E. Jacquemin, M. Fabre, S. Lyonnet, Y. De Prost, A. Munnich, M. Hadchouel, et al. 2004. Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: a tight junction disease. Gastroenterology. 127: 1386-1390.
-
(2004)
Gastroenterology
, vol.127
, pp. 1386-1390
-
-
Hadj-Rabia, S.1
Baala, L.2
Vabres, P.3
Hamel-Teillac, D.4
Jacquemin, E.5
Fabre, M.6
Lyonnet, S.7
De Prost, Y.8
Munnich, A.9
Hadchouel, M.10
-
67
-
-
33847011377
-
Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration
-
Geier, A., M. Wagner, C. G. Dietrich, and M. Trauner. 2007. Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration. Biochim. Biophys. Acta. 1773: 283-308.
-
(2007)
Biochim. Biophys. Acta
, vol.1773
, pp. 283-308
-
-
Geier, A.1
Wagner, M.2
Dietrich, C.G.3
Trauner, M.4
-
68
-
-
1542724881
-
Cellular regulation of hepatic bile acid transport in health and cholestasis
-
Anwer, M. S. 2004. Cellular regulation of hepatic bile acid transport in health and cholestasis. Hepatology. 39: 581-590.
-
(2004)
Hepatology
, vol.39
, pp. 581-590
-
-
Anwer, M.S.1
-
69
-
-
15844426563
-
Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter
-
Karpen, S. J., A. Q. Sun, B. Kudish, B. Hagenbuch, P. J. Meier, M. Ananthanarayanan, and F. J. Suchy. 1996. Multiple factors regulate the rat liver basolateral sodium-dependent bile acid cotransporter gene promoter. J. Biol. Chem. 271: 15211-15221.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 15211-15221
-
-
Karpen, S.J.1
Sun, A.Q.2
Kudish, B.3
Hagenbuch, B.4
Meier, P.J.5
Ananthanarayanan, M.6
Suchy, F.J.7
-
70
-
-
0034950514
-
The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp
-
Denson, L. A., E. Sturm, W. Echevarria, T. L. Zimmerman, M. Makishima, D. J. Mangelsdorf, and S. J. Karpen. 2001. The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp. Gastroenterology. 121: 140-147.
-
(2001)
Gastroenterology
, vol.121
, pp. 140-147
-
-
Denson, L.A.1
Sturm, E.2
Echevarria, W.3
Zimmerman, T.L.4
Makishima, M.5
Mangelsdorf, D.J.6
Karpen, S.J.7
-
72
-
-
0037371120
-
Hepatocyte nuclear factor 1 alpha: A key mediator of the effect of bile acids on gene expression
-
Jung, D., and G. A. Kullak-Ublick. 2003. Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression. Hepatology. 37: 622-631.
-
(2003)
Hepatology
, vol.37
, pp. 622-631
-
-
Jung, D.1
Kullak-Ublick, G.A.2
-
73
-
-
1942423712
-
Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene
-
Jung, D., B. Hagenbuch, M. Fried, P. J. Meier, and G. A. Kullak- Ublick. 2004. Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene. Am. J. Physiol. Gastrointest. Liver Physiol. 286: G752-G761.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.286
-
-
Jung, D.1
Hagenbuch, B.2
Fried, M.3
Meier, P.J.4
Kullak- Ublick, G.A.5
-
74
-
-
0033776792
-
Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes infl uence expression of genes involved in bile acid and glucose homeostasis
-
Rausa, F. M., Y. Tan, H. Zhou, K. W. Yoo, D. B. Stolz, S. C. Watkins, R. R. Franks, T. G. Unterman, and R. H. Costa. 2000. Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes infl uence expression of genes involved in bile acid and glucose homeostasis. Mol. Cell. Biol. 20: 8264-8282.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 8264-8282
-
-
Rausa, F.M.1
Tan, Y.2
Zhou, H.3
Yoo, K.W.4
Stolz, D.B.5
Watkins, S.C.6
Franks, R.R.7
Unterman, T.G.8
Costa, R.H.9
-
75
-
-
44649202231
-
Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis
-
Lee, Y. K., D. R. Schmidt, C. L. Cummins, M. Choi, L. Peng, Y. Zhang, B. Goodwin, R. E. Hammer, D. J. Mangelsdorf, and S. A. Kliewer. 2008. Liver receptor homolog-1 regulates bile acid homeostasis but is not essential for feedback regulation of bile acid synthesis. Mol. Endocrinol. 22: 1345-1356.
-
(2008)
Mol. Endocrinol
, vol.22
, pp. 1345-1356
-
-
Lee, Y.K.1
Schmidt, D.R.2
Cummins, C.L.3
Choi, M.4
Peng, L.5
Zhang, Y.6
Goodwin, B.7
Hammer, R.E.8
Mangelsdorf, D.J.9
Kliewer, S.A.10
-
76
-
-
29444434655
-
The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism
-
Eloranta, J. J., D. Jung, and G. A. Kullak-Ublick. 2006. The human Na+-taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechanism. Mol. Endocrinol. 20: 65-79.
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 65-79
-
-
Eloranta, J.J.1
Jung, D.2
Kullak-Ublick, G.A.3
-
77
-
-
0035141324
-
Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis
-
Hayhurst, G. P., Y. H. Lee, G. Lambert, J. M. Ward, and F. J. Gonzalez. 2001. Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis. Mol. Cell. Biol. 21: 1393-1403.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 1393-1403
-
-
Hayhurst, G.P.1
Lee, Y.H.2
Lambert, G.3
Ward, J.M.4
Gonzalez, F.J.5
-
78
-
-
52449097513
-
Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene
-
Geier, A., I. V. Martin, C. G. Dietrich, N. Balasubramaniyan, S. Strauch, F. J. Suchy, C. Gartung, C. Trautwein, and M. Ananthanarayanan. 2008. Hepatocyte nuclear factor-4alpha is a central transactivator of the mouse Ntcp gene. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G226-G233.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.295
-
-
Geier, A.1
Martin, I.V.2
Dietrich, C.G.3
Balasubramaniyan, N.4
Strauch, S.5
Suchy, F.J.6
Gartung, C.7
Trautwein, C.8
Ananthanarayanan, M.9
-
79
-
-
34548747628
-
Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha
-
Dietrich, C. G., I. V. Martin, A. C. Porn, S. Voigt, C. Gartung, C. Trautwein, and A. Geier. 2007. Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha. Am. J. Physiol. Gastrointest. Liver Physiol. 293: G585-G590.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.293
-
-
Dietrich, C.G.1
Martin, I.V.2
Porn, A.C.3
Voigt, S.4
Gartung, C.5
Trautwein, C.6
Geier, A.7
-
80
-
-
0242582371
-
Resistance of SHP-null mice to bile acid-induced liver damage
-
Wang, L., Y. Han, C. S. Kim, Y. K. Lee, and D. D. Moore. 2003. Resistance of SHP-null mice to bile acid-induced liver damage. J. Biol. Chem. 278: 44475-44481.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 44475-44481
-
-
Wang, L.1
Han, Y.2
Kim, C.S.3
Lee, Y.K.4
Moore, D.D.5
-
81
-
-
49149090637
-
Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress
-
Bochkis, I. M., N. E. Rubins, P. White, E. E. Furth, J. R. Friedman, and K. H. Kaestner. 2008. Hepatocyte-specific ablation of Foxa2 alters bile acid homeostasis and results in endoplasmic reticulum stress. Nat. Med. 14: 828-836.
-
(2008)
Nat. Med
, vol.14
, pp. 828-836
-
-
Bochkis, I.M.1
Rubins, N.E.2
White, P.3
Furth, E.E.4
Friedman, J.R.5
Kaestner, K.H.6
-
82
-
-
0035844156
-
Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway
-
Gupta, S., R. T. Stravitz, P. Dent, and P. B. Hylemon. 2001. Down-regulation of cholesterol 7alpha-hydroxylase (CYP7A1) gene expression by bile acids in primary rat hepatocytes is mediated by the c-Jun N-terminal kinase pathway. J. Biol. Chem. 276: 15816-15822.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 15816-15822
-
-
Gupta, S.1
Stravitz, R.T.2
Dent, P.3
Hylemon, P.B.4
-
83
-
-
0037200089
-
Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent
-
Li, D., T. L. Zimmerman, S. Thevananther, H. Y. Lee, J. M. Kurie, and S. J. Karpen. 2002. Interleukin-1 beta-mediated suppression of RXR:RAR transactivation of the Ntcp promoter is JNK-dependent. J. Biol. Chem. 277: 31416-31422.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 31416-31422
-
-
Li, D.1
Zimmerman, T.L.2
Thevananther, S.3
Lee, H.Y.4
Kurie, J.M.5
Karpen, S.J.6
-
84
-
-
0029886277
-
Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents
-
Green, R. M., D. Beier, and J. L. Gollan. 1996. Regulation of hepatocyte bile salt transporters by endotoxin and inflammatory cytokines in rodents. Gastroenterology. 111: 193-198.
-
(1996)
Gastroenterology
, vol.111
, pp. 193-198
-
-
Green, R.M.1
Beier, D.2
Gollan, J.L.3
-
85
-
-
4143070233
-
Interleukin-6 regulates hepatic transporters during acute-phase response
-
Siewert, E., C. G. Dietrich, F. Lammert, P. C. Heinrich, S. Matern, C. Gartung, and A. Geier. 2004. Interleukin-6 regulates hepatic transporters during acute-phase response. Biochem. Biophys. Res. Commun. 322: 232-238.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.322
, pp. 232-238
-
-
Siewert, E.1
Dietrich, C.G.2
Lammert, F.3
Heinrich, P.C.4
Matern, S.5
Gartung, C.6
Geier, A.7
-
86
-
-
0032524012
-
Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors
-
Trauner, M., M. Arrese, H. Lee, J. L. Boyer, and S. J. Karpen. 1998. Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors. J. Clin. Invest. 101: 2092-2100.
-
(1998)
J. Clin. Invest
, vol.101
, pp. 2092-2100
-
-
Trauner, M.1
Arrese, M.2
Lee, H.3
Boyer, J.L.4
Karpen, S.J.5
-
87
-
-
61449142646
-
Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6
-
Vee, M. L., V. Lecureur, B. Stieger, and O. Fardel. 2009. Regulation of drug transporter expression in human hepatocytes exposed to the proinflammatory cytokines tumor necrosis factor-alpha or interleukin-6. Drug Metab. Dispos. 37: 685-693.
-
(2009)
Drug Metab. Dispos
, vol.37
, pp. 685-693
-
-
Vee, M.L.1
Lecureur, V.2
Stieger, B.3
Fardel, O.4
-
88
-
-
0042766885
-
Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis
-
Geier, A., C. G. Dietrich, S. Voigt, S. K. Kim, T. Gerloff, G. A. Kullak-Ublick, J. Lorenzen, S. Matern, and C. Gartung. 2003. Effects of proinflammatory cytokines on rat organic anion transporters during toxic liver injury and cholestasis. Hepatology. 38: 345-354.
-
(2003)
Hepatology
, vol.38
, pp. 345-354
-
-
Geier, A.1
Dietrich, C.G.2
Voigt, S.3
Kim, S.K.4
Gerloff, T.5
Kullak-Ublick, G.A.6
Lorenzen, J.7
Matern, S.8
Gartung, C.9
-
89
-
-
33847350212
-
Differential regulation of hepatic transporters in the absence of tumor necrosis factor-alpha, interleukin-1-beta, interleukin-6, and nuclear factor-kappaB in two models of cholestasis
-
Lickteig, A. J., A. L. Slitt, M. C. Arkan, M. Karin, and N. J. Cherrington. 2007. Differential regulation of hepatic transporters in the absence of tumor necrosis factor-alpha, interleukin-1-beta, interleukin-6, and nuclear factor-kappaB in two models of cholestasis. Drug Metab. Dispos. 35: 402-409.
-
(2007)
Drug Metab. Dispos
, vol.35
, pp. 402-409
-
-
Lickteig, A.J.1
Slitt, A.L.2
Arkan, M.C.3
Karin, M.4
Cherrington, N.J.5
-
90
-
-
0036086893
-
Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice
-
Zollner, G., P. Fickert, D. Silbert, A. Fuchsbichler, C. Stumptner, K. Zatloukal, H. Denk, and M. Trauner. 2002. Induction of short heterodimer partner 1 precedes downregulation of Ntcp in bile duct-ligated mice. Am. J. Physiol. Gastrointest. Liver Physiol. 282: G184-G191.
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.282
-
-
Zollner, G.1
Fickert, P.2
Silbert, D.3
Fuchsbichler, A.4
Stumptner, C.5
Zatloukal, K.6
Denk, H.7
Trauner, M.8
-
91
-
-
27444434833
-
Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver
-
Zollner, G., M. Wagner, P. Fickert, A. Geier, A. Fuchsbichler, D. Silbert, J. Gumhold, K. Zatloukal, A. Kaser, H. Tilg, et al. 2005. Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G798-G805.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.289
-
-
Zollner, G.1
Wagner, M.2
Fickert, P.3
Geier, A.4
Fuchsbichler, A.5
Silbert, D.6
Gumhold, J.7
Zatloukal, K.8
Kaser, A.9
Tilg, H.10
-
92
-
-
0033986961
-
The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: Two mechanisms for repression
-
Lee, Y. K., H. Dell, D. H. Dowhan, M. Hadzopoulou-Cladaras, and D. D. Moore. 2000. The orphan nuclear receptor SHP inhibits hepatocyte nuclear factor 4 and retinoid X receptor transactivation: two mechanisms for repression. Mol. Cell. Biol. 20: 187-195.
-
(2000)
Mol. Cell. Biol
, vol.20
, pp. 187-195
-
-
Lee, Y.K.1
Dell, H.2
Dowhan, D.H.3
Hadzopoulou-Cladaras, M.4
Moore, D.D.5
-
93
-
-
33744957050
-
Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: Roles for JNK and SER260
-
Zimmerman, T. L., S. Thevananther, R. Ghose, A. R. Burns, and S. J. Karpen. 2006. Nuclear export of retinoid X receptor alpha in response to interleukin-1beta-mediated cell signaling: roles for JNK and SER260. J. Biol. Chem. 281: 15434-15440.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 15434-15440
-
-
Zimmerman, T.L.1
Thevananther, S.2
Ghose, R.3
Burns, A.R.4
Karpen, S.J.5
-
94
-
-
18144387309
-
Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: A novel mechanism for reduced hepatic gene expression in inflammation
-
Ghose, R., T. L. Zimmerman, S. Thevananther, and S. J. Karpen. 2004. Endotoxin leads to rapid subcellular re-localization of hepatic RXRalpha: a novel mechanism for reduced hepatic gene expression in inflammation. Nucl. Recept. 2: 4.
-
(2004)
Nucl. Recept
, vol.2
, pp. 4
-
-
Ghose, R.1
Zimmerman, T.L.2
Thevananther, S.3
Karpen, S.J.4
-
95
-
-
27444441206
-
Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver
-
Geier, A., C. G. Dietrich, S. Voigt, M. Ananthanarayanan, F. Lammert, A. Schmitz, M. Trauner, H. E. Wasmuth, D. Boraschi, N. Balasubramaniyan, et al. 2005. Cytokine-dependent regulation of hepatic organic anion transporter gene transactivators in mouse liver. Am. J. Physiol. Gastrointest. Liver Physiol. 289: G831-G841.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.289
-
-
Geier, A.1
Dietrich, C.G.2
Voigt, S.3
Ananthanarayanan, M.4
Lammert, F.5
Schmitz, A.6
Trauner, M.7
Wasmuth, H.E.8
Boraschi, D.9
Balasubramaniyan, N.10
-
96
-
-
0034768779
-
Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver
-
Wang, B., S. R. Cai, C. Gao, F. M. Sladek, and K. P. Ponder. 2001. Lipopolysaccharide results in a marked decrease in hepatocyte nuclear factor 4 alpha in rat liver. Hepatology. 34: 979-989.
-
(2001)
Hepatology
, vol.34
, pp. 979-989
-
-
Wang, B.1
Cai, S.R.2
Gao, C.3
Sladek, F.M.4
Ponder, K.P.5
-
97
-
-
0030848766
-
Modulation of hepatic gene expression by hepatocyte nuclear factor 1
-
Ktistaki, E., and I. Talianidis. 1997. Modulation of hepatic gene expression by hepatocyte nuclear factor 1. Science. 277: 109-112.
-
(1997)
Science
, vol.277
, pp. 109-112
-
-
Ktistaki, E.1
Talianidis, I.2
-
98
-
-
10744227070
-
Control of pancreas and liver gene expression by HNF transcription factors
-
Odom, D. T., N. Zizlsperger, D. B. Gordon, G. W. Bell, N. J. Rinaldi, H. L. Murray, T. L. Volkert, J. Schreiber, P. A. Rolfe, D. K. Gifford, et al. 2004. Control of pancreas and liver gene expression by HNF transcription factors. Science. 303: 1378-1381.
-
(2004)
Science
, vol.303
, pp. 1378-1381
-
-
Odom, D.T.1
Zizlsperger, N.2
Gordon, D.B.3
Bell, G.W.4
Rinaldi, N.J.5
Murray, H.L.6
Volkert, T.L.7
Schreiber, J.8
Rolfe, P.A.9
Gifford, D.K.10
-
99
-
-
20044380329
-
Cytokine-independent repression of rodent Ntcp in obstructive cholestasis
-
Geier, A., G. Zollner, C. G. Dietrich, M. Wagner, P. Fickert, H. Denk, N. van Rooijen, S. Matern, C. Gartung, and M. Trauner. 2005. Cytokine-independent repression of rodent Ntcp in obstructive cholestasis. Hepatology. 41: 470-477.
-
(2005)
Hepatology
, vol.41
, pp. 470-477
-
-
Geier, A.1
Zollner, G.2
Dietrich, C.G.3
Wagner, M.4
Fickert, P.5
Denk, H.6
van Rooijen, N.7
Matern, S.8
Gartung, C.9
Trauner, M.10
-
100
-
-
84920357266
-
Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver
-
Gerloff, T., A. Geier, B. Stieger, B. Hagenbuch, P. J. Meier, S. Matern, and C. Gartung. 1999. Differential expression of basolateral and canalicular organic anion transporters during regeneration of rat liver. Gastroenterology. 117: 1408-1415.
-
(1999)
Gastroenterology
, vol.117
, pp. 1408-1415
-
-
Gerloff, T.1
Geier, A.2
Stieger, B.3
Hagenbuch, B.4
Meier, P.J.5
Matern, S.6
Gartung, C.7
-
101
-
-
0036022841
-
Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride
-
Geier, A., S. K. Kim, T. Gerloff, C. G. Dietrich, F. Lammert, S. J. Karpen, B. Stieger, P. J. Meier, S. Matern, and C. Gartung. 2002. Hepatobiliary organic anion transporters are differentially regulated in acute toxic liver injury induced by carbon tetrachloride. J. Hepatol. 37: 198-205.
-
(2002)
J. Hepatol
, vol.37
, pp. 198-205
-
-
Geier, A.1
Kim, S.K.2
Gerloff, T.3
Dietrich, C.G.4
Lammert, F.5
Karpen, S.J.6
Stieger, B.7
Meier, P.J.8
Matern, S.9
Gartung, C.10
-
102
-
-
0030994363
-
Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5
-
Ganguly, T. C., M. L. O'Brien, S. J. Karpen, J. F. Hyde, F. J. Suchy, and M. Vore. 1997. Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5. J. Clin. Invest. 99: 2906-2914.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 2906-2914
-
-
Ganguly, T.C.1
O'Brien, M.L.2
Karpen, S.J.3
Hyde, J.F.4
Suchy, F.J.5
Vore, M.6
-
103
-
-
0034807523
-
PRL, placental lactogen, and GH induce NA(+)/ taurocholate-cotransporting polypeptide gene expression by activating signal transducer and activator of transcription-5 in liver cells
-
Cao, J., P. M. Gowri, T. C. Ganguly, M. Wood, J. F. Hyde, F. Talamantes, and M. Vore. 2001. PRL, placental lactogen, and GH induce NA(+)/ taurocholate-cotransporting polypeptide gene expression by activating signal transducer and activator of transcription-5 in liver cells. Endocrinology. 142: 4212-4222.
-
(2001)
Endocrinology
, vol.142
, pp. 4212-4222
-
-
Cao, J.1
Gowri, P.M.2
Ganguly, T.C.3
Wood, M.4
Hyde, J.F.5
Talamantes, F.6
Vore, M.7
-
104
-
-
4644313920
-
Multihormonal regulation of hepatic sinusoidal Ntcp gene expression
-
Simon, F. R., J. Fortune, M. Iwahashi, I. Qadri, and E. Sutherland. 2004. Multihormonal regulation of hepatic sinusoidal Ntcp gene expression. Am. J. Physiol. Gastrointest. Liver Physiol. 287: G782-G794.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.287
-
-
Simon, F.R.1
Fortune, J.2
Iwahashi, M.3
Qadri, I.4
Sutherland, E.5
-
105
-
-
0030784779
-
cAMP increases liver Na+-taurocholate cotransport by translocating transporter to plasma membranes
-
Mukhopadhayay, S., M. Ananthanarayanan, B. Stieger, P. J. Meier, F. J. Suchy, and M. S. Anwer. 1997. cAMP increases liver Na+-taurocholate cotransport by translocating transporter to plasma membranes. Am. J. Physiol. 273: G842-G848.
-
(1997)
Am. J. Physiol
, vol.273
-
-
Mukhopadhayay, S.1
Ananthanarayanan, M.2
Stieger, B.3
Meier, P.J.4
Suchy, F.J.5
Anwer, M.S.6
-
106
-
-
0027295492
-
Role of intracellular calcium and protein kinases in the activation of hepatic Na+/ taurocholate cotransport by cyclic AMP
-
Grune, S., L. R. Engelking, and M. S. Anwer. 1993. Role of intracellular calcium and protein kinases in the activation of hepatic Na+/ taurocholate cotransport by cyclic AMP. J. Biol. Chem. 268: 17734-17741.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 17734-17741
-
-
Grune, S.1
Engelking, L.R.2
Anwer, M.S.3
-
107
-
-
0032491597
-
Role of protein phosphatases in cyclic AMP-mediated stimulation of hepatic Na+/ taurocholate cotransport
-
Mukhopadhyay, S., C. R. Webster, and M. S. Anwer. 1998. Role of protein phosphatases in cyclic AMP-mediated stimulation of hepatic Na+/ taurocholate cotransport. J. Biol. Chem. 273: 30039-30045.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 30039-30045
-
-
Mukhopadhyay, S.1
Webster, C.R.2
Anwer, M.S.3
-
108
-
-
0031738338
-
Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate
-
Mukhopadhyay, S., M. Ananthanarayanan, B. Stieger, P. J. Meier, F. J. Suchy, and M. S. Anwer. 1998. Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate. Hepatology. 28: 1629-1636.
-
(1998)
Hepatology
, vol.28
, pp. 1629-1636
-
-
Mukhopadhyay, S.1
Ananthanarayanan, M.2
Stieger, B.3
Meier, P.J.4
Suchy, F.J.5
Anwer, M.S.6
-
109
-
-
0032995996
-
Short-term regulation of bile acid uptake by microfilamentdependent translocation of rat ntcp to the plasma membrane
-
Dranoff, J. A., M. McClure, A. D. Burgstahler, L. A. Denson, A. R. Crawford, J. M. Crawford, S. J. Karpen, and M. H. Nathanson. 1999. Short-term regulation of bile acid uptake by microfilamentdependent translocation of rat ntcp to the plasma membrane. Hepatology. 30: 223-229.
-
(1999)
Hepatology
, vol.30
, pp. 223-229
-
-
Dranoff, J.A.1
McClure, M.2
Burgstahler, A.D.3
Denson, L.A.4
Crawford, A.R.5
Crawford, J.M.6
Karpen, S.J.7
Nathanson, M.H.8
-
110
-
-
25844499830
-
Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp
-
Anwer, M. S., H. Gillin, S. Mukhopadhyay, N. Balasubramaniyan, F. J. Suchy, and M. Ananthanarayanan. 2005. Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp. J. Biol. Chem. 280: 33687-33692.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 33687-33692
-
-
Anwer, M.S.1
Gillin, H.2
Mukhopadhyay, S.3
Balasubramaniyan, N.4
Suchy, F.J.5
Ananthanarayanan, M.6
-
112
-
-
0037047389
-
Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation
-
Webster, C. R., U. Srinivasulu, M. Ananthanarayanan, F. J. Suchy, and M. S. Anwer. 2002. Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na+/taurocholate cotransport and Ntcp translocation. J. Biol. Chem. 277: 28578-28583.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 28578-28583
-
-
Webster, C.R.1
Srinivasulu, U.2
Ananthanarayanan, M.3
Suchy, F.J.4
Anwer, M.S.5
-
113
-
-
2442681520
-
Cross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytes
-
McConkey, M., H. Gillin, C. R. Webster, and M. S. Anwer. 2004. Cross-talk between protein kinases Czeta and B in cyclic AMP-mediated sodium taurocholate co-transporting polypeptide translocation in hepatocytes. J. Biol. Chem. 279: 20882-20888.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 20882-20888
-
-
McConkey, M.1
Gillin, H.2
Webster, C.R.3
Anwer, M.S.4
-
114
-
-
33745757459
-
PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter
-
Sarkar, S., E. Bananis, S. Nath, M. S. Anwer, A. W. Wolkoff, and J. W. Murray. 2006. PKCzeta is required for microtubule-based motility of vesicles containing the ntcp transporter. Traffic. 7: 1078-1091.
-
(2006)
Traffic
, vol.7
, pp. 1078-1091
-
-
Sarkar, S.1
Bananis, E.2
Nath, S.3
Anwer, M.S.4
Wolkoff, A.W.5
Murray, J.W.6
-
115
-
-
42249111198
-
Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes
-
Schonhoff, C. M., H. Gillin, C. R. Webster, and M. S. Anwer. 2008. Protein kinase Cdelta mediates cyclic adenosine monophosphate-stimulated translocation of sodium taurocholate cotransporting polypeptide and multidrug resistant associated protein 2 in rat hepatocytes. Hepatology. 47: 1309-1316.
-
(2008)
Hepatology
, vol.47
, pp. 1309-1316
-
-
Schonhoff, C.M.1
Gillin, H.2
Webster, C.R.3
Anwer, M.S.4
-
116
-
-
0036828271
-
Functional expression of the canalicular bile salt export pump of human liver
-
Noe, J., B. Stieger, and P. J. Meier. 2002. Functional expression of the canalicular bile salt export pump of human liver. Gastroenterology. 123: 1659-1666.
-
(2002)
Gastroenterology
, vol.123
, pp. 1659-1666
-
-
Noe, J.1
Stieger, B.2
Meier, P.J.3
-
117
-
-
0036829089
-
The human bile salt export pump: Characterization of substrate specificity and identification of inhibitors
-
Byrne, J. A., S. S. Strautnieks, G. Mieli-Vergani, C. F. Higgins, K. J. Linton, and R. J. Thompson. 2002. The human bile salt export pump: characterization of substrate specificity and identification of inhibitors. Gastroenterology. 123: 1649-1658.
-
(2002)
Gastroenterology
, vol.123
, pp. 1649-1658
-
-
Byrne, J.A.1
Strautnieks, S.S.2
Mieli-Vergani, G.3
Higgins, C.F.4
Linton, K.J.5
Thompson, R.J.6
-
118
-
-
0037313267
-
Differential developmental regulation of rat liver canalicular membrane transporters Bsep and Mrp2
-
Tomer, G., M. Ananthanarayanan, A. Weymann, N. Balasubramanian, and F. J. Suchy. 2003. Differential developmental regulation of rat liver canalicular membrane transporters Bsep and Mrp2. Pediatr. Res. 53: 288-294.
-
(2003)
Pediatr. Res
, vol.53
, pp. 288-294
-
-
Tomer, G.1
Ananthanarayanan, M.2
Weymann, A.3
Balasubramanian, N.4
Suchy, F.J.5
-
119
-
-
4444266366
-
Differential expression of bile salt and organic anion transporters in developing rat liver
-
Gao, B., M. V. St Pierre, B. Stieger, and P. J. Meier. 2004. Differential expression of bile salt and organic anion transporters in developing rat liver. J. Hepatol. 41: 201-208.
-
(2004)
J. Hepatol
, vol.41
, pp. 201-208
-
-
Gao, B.1
St Pierre, M.V.2
Stieger, B.3
Meier, P.J.4
-
120
-
-
17344366172
-
A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis
-
Strautnieks, S. S., L. N. Bull, A. S. Knisely, S. A. Kocoshis, N. Dahl, H. Arnell, E. Sokal, K. Dahan, S. Childs, V. Ling, et al. 1998. A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. Nat. Genet. 20: 233-238.
-
(1998)
Nat. Genet
, vol.20
, pp. 233-238
-
-
Strautnieks, S.S.1
Bull, L.N.2
Knisely, A.S.3
Kocoshis, S.A.4
Dahl, N.5
Arnell, H.6
Sokal, E.7
Dahan, K.8
Childs, S.9
Ling, V.10
-
121
-
-
41549123313
-
Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families
-
Strautnieks, S. S., J. A. Byrne, L. Pawlikowska, D. Cebecauerova, A. Rayner, L. Dutton, Y. Meier, A. Antoniou, B. Stieger, H. Arnell, et al. 2008. Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families. Gastroenterology. 134: 1203-1214.
-
(2008)
Gastroenterology
, vol.134
, pp. 1203-1214
-
-
Strautnieks, S.S.1
Byrne, J.A.2
Pawlikowska, L.3
Cebecauerova, D.4
Rayner, A.5
Dutton, L.6
Meier, Y.7
Antoniou, A.8
Stieger, B.9
Arnell, H.10
-
122
-
-
31044446504
-
Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: A comparison of human BSEP with rat Bsep
-
Hayashi, H., T. Takada, H. Suzuki, R. Onuki, A. F. Hofmann, and Y. Sugiyama. 2005. Transport by vesicles of glycine- and taurine-conjugated bile salts and taurolithocholate 3-sulfate: a comparison of human BSEP with rat Bsep. Biochim. Biophys. Acta. 1738: 54-62.
-
(2005)
Biochim. Biophys. Acta
, vol.1738
, pp. 54-62
-
-
Hayashi, H.1
Takada, T.2
Suzuki, H.3
Onuki, R.4
Hofmann, A.F.5
Sugiyama, Y.6
-
123
-
-
22944458539
-
Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin
-
Hirano, M., K. Maeda, H. Hayashi, H. Kusuhara, and Y. Sugiyama. 2005. Bile salt export pump (BSEP/ABCB11) can transport a nonbile acid substrate, pravastatin. J. Pharmacol. Exp. Ther. 314: 876-882.
-
(2005)
J. Pharmacol. Exp. Ther
, vol.314
, pp. 876-882
-
-
Hirano, M.1
Maeda, K.2
Hayashi, H.3
Kusuhara, H.4
Sugiyama, Y.5
-
124
-
-
85009593103
-
Potential cholestatic activity of various therapeutic agents assessed by bile canalicular membrane vesicles isolated from rats and humans
-
Horikawa, M., Y. Kato, C. A. Tyson, and Y. Sugiyama. 2003. Potential cholestatic activity of various therapeutic agents assessed by bile canalicular membrane vesicles isolated from rats and humans. Drug Metab. Pharmacokinet. 18: 16-22.
-
(2003)
Drug Metab. Pharmacokinet
, vol.18
, pp. 16-22
-
-
Horikawa, M.1
Kato, Y.2
Tyson, C.A.3
Sugiyama, Y.4
-
125
-
-
33747032310
-
Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency
-
Knisely, A. S., S. S. Strautnieks, Y. Meier, B. Stieger, J. A. Byrne, B. C. Portmann, L. N. Bull, L. Pawlikowska, B. Bilezikci, F. Ozcay, et al. 2006. Hepatocellular carcinoma in ten children under five years of age with bile salt export pump deficiency. Hepatology. 44: 478-486.
-
(2006)
Hepatology
, vol.44
, pp. 478-486
-
-
Knisely, A.S.1
Strautnieks, S.S.2
Meier, Y.3
Stieger, B.4
Byrne, J.A.5
Portmann, B.C.6
Bull, L.N.7
Pawlikowska, L.8
Bilezikci, B.9
Ozcay, F.10
-
126
-
-
4143073631
-
Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11
-
van Mil, S. W., W. L. van der Woerd, G. van der Brugge, E. Sturm, P. L. Jansen, L. N. Bull, I. E. van den Berg, R. Berger, R. H. Houwen, and L. W. Klomp. 2004. Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11. Gastroenterology. 127: 379-384.
-
(2004)
Gastroenterology
, vol.127
, pp. 379-384
-
-
van Mil, S.W.1
van der Woerd, W.L.2
van der Brugge, G.3
Sturm, E.4
Jansen, P.L.5
Bull, L.N.6
van den Berg, I.E.7
Berger, R.8
Houwen, R.H.9
Klomp, L.W.10
-
127
-
-
61949292897
-
Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing
-
Byrne, J. A., S. S. Strautnieks, G. Ihrke, F. Pagani, A. S. Knisely, K. J. Linton, G. Mieli-Vergani, and R. J. Thompson. 2009. Missense mutations and single nucleotide polymorphisms in ABCB11 impair bile salt export pump processing and function or disrupt pre-messenger RNA splicing. Hepatology. 49: 553-567.
-
(2009)
Hepatology
, vol.49
, pp. 553-567
-
-
Byrne, J.A.1
Strautnieks, S.S.2
Ihrke, G.3
Pagani, F.4
Knisely, A.S.5
Linton, K.J.6
Mieli-Vergani, G.7
Thompson, R.J.8
-
128
-
-
33750610841
-
Hepatobiliary transporters and drug-induced cholestasis
-
Pauli-Magnus, C., and P. J. Meier. 2006. Hepatobiliary transporters and drug-induced cholestasis. Hepatology. 44: 778-787.
-
(2006)
Hepatology
, vol.44
, pp. 778-787
-
-
Pauli-Magnus, C.1
Meier, P.J.2
-
129
-
-
64149086618
-
Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy
-
Dixon, P. H., S. W. van Mil, J. Chambers, S. Strautnieks, R. J. Thompson, F. Lammert, R. Kubitz, V. Keitel, A. Glantz, L. A. Mattsson, et al. 2009. Contribution of variant alleles of ABCB11 to susceptibility to intrahepatic cholestasis of pregnancy. Gut. 58: 537-544.
-
(2009)
Gut
, vol.58
, pp. 537-544
-
-
Dixon, P.H.1
van Mil, S.W.2
Chambers, J.3
Strautnieks, S.4
Thompson, R.J.5
Lammert, F.6
Kubitz, R.7
Keitel, V.8
Glantz, A.9
Mattsson, L.A.10
-
130
-
-
0036847090
-
Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice
-
Wolters, H., B. M. Elzinga, J. F. Baller, R. Boverhof, M. Schwarz, B. Stieger, H. J. Verkade, and F. Kuipers. 2002. Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice. J. Hepatol. 37: 556-563.
-
(2002)
J. Hepatol
, vol.37
, pp. 556-563
-
-
Wolters, H.1
Elzinga, B.M.2
Baller, J.F.3
Boverhof, R.4
Schwarz, M.5
Stieger, B.6
Verkade, H.J.7
Kuipers, F.8
-
131
-
-
0013138711
-
Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis
-
Zollner, G., P. Fickert, D. Silbert, A. Fuchsbichler, H. U. Marschall, K. Zatloukal, H. Denk, and M. Trauner. 2003. Adaptive changes in hepatobiliary transporter expression in primary biliary cirrhosis. J. Hepatol. 38: 717-727.
-
(2003)
J. Hepatol
, vol.38
, pp. 717-727
-
-
Zollner, G.1
Fickert, P.2
Silbert, D.3
Fuchsbichler, A.4
Marschall, H.U.5
Zatloukal, K.6
Denk, H.7
Trauner, M.8
-
132
-
-
0042825756
-
Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice
-
Wagner, M., P. Fickert, G. Zollner, A. Fuchsbichler, D. Silbert, O. Tsybrovskyy, K. Zatloukal, G. L. Guo, J. D. Schuetz, F. J. Gonzalez, et al. 2003. Role of farnesoid X receptor in determining hepatic ABC transporter expression and liver injury in bile duct-ligated mice. Gastroenterology. 125: 825-838.
-
(2003)
Gastroenterology
, vol.125
, pp. 825-838
-
-
Wagner, M.1
Fickert, P.2
Zollner, G.3
Fuchsbichler, A.4
Silbert, D.5
Tsybrovskyy, O.6
Zatloukal, K.7
Guo, G.L.8
Schuetz, J.D.9
Gonzalez, F.J.10
-
133
-
-
0035800772
-
Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor
-
Ananthanarayanan, M., N. Balasubramanian, M. Makishima, D. J. Mangelsdorf, and F. J. Suchy. 2001. Human bile salt export pump promoter is transactivated by the farnesoid X receptor/bile acid receptor. J. Biol. Chem. 276: 28857-28865.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 28857-28865
-
-
Ananthanarayanan, M.1
Balasubramanian, N.2
Makishima, M.3
Mangelsdorf, D.J.4
Suchy, F.J.5
-
134
-
-
0036186337
-
Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump
-
Plass, J. R., O. Mol, J. Heegsma, M. Geuken, K. N. Faber, P. L. Jansen, and M. Muller. 2002. Farnesoid X receptor and bile salts are involved in transcriptional regulation of the gene encoding the human bile salt export pump. Hepatology. 35: 589-596.
-
(2002)
Hepatology
, vol.35
, pp. 589-596
-
-
Plass, J.R.1
Mol, O.2
Heegsma, J.3
Geuken, M.4
Faber, K.N.5
Jansen, P.L.6
Muller, M.7
-
135
-
-
0034664729
-
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis
-
Sinal, C. J., M. Tohkin, M. Miyata, J. M. Ward, G. Lambert, and F. J. Gonzalez. 2000. Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis. Cell. 102: 731-744.
-
(2000)
Cell
, vol.102
, pp. 731-744
-
-
Sinal, C.J.1
Tohkin, M.2
Miyata, M.3
Ward, J.M.4
Lambert, G.5
Gonzalez, F.J.6
-
136
-
-
12444301770
-
Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine
-
Zollner, G., P. Fickert, A. Fuchsbichler, D. Silbert, M. Wagner, S. Arbeiter, F. J. Gonzalez, H. U. Marschall, K. Zatloukal, H. Denk, et al. 2003. Role of nuclear bile acid receptor, FXR, in adaptive ABC transporter regulation by cholic and ursodeoxycholic acid in mouse liver, kidney and intestine. J. Hepatol. 39: 480-488.
-
(2003)
J. Hepatol
, vol.39
, pp. 480-488
-
-
Zollner, G.1
Fickert, P.2
Fuchsbichler, A.3
Silbert, D.4
Wagner, M.5
Arbeiter, S.6
Gonzalez, F.J.7
Marschall, H.U.8
Zatloukal, K.9
Denk, H.10
-
137
-
-
0033591387
-
Bile acids: Natural ligands for an orphan nuclear receptor
-
Parks, D. J., S. G. Blanchard, R. K. Bledsoe, G. Chandra, T. G. Consler, S. A. Kliewer, J. B. Stimmel, T. M. Willson, A. M. Zavacki, D. D. Moore, et al. 1999. Bile acids: natural ligands for an orphan nuclear receptor. Science. 284: 1365-1368.
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
-
138
-
-
1542275425
-
The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion
-
Lew, J. L., A. Zhao, J. Yu, L. Huang, N. De Pedro, F. Pelaez, S. D. Wright, and J. Cui. 2004. The farnesoid X receptor controls gene expression in a ligand- and promoter-selective fashion. J. Biol. Chem. 279: 8856-8861.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 8856-8861
-
-
Lew, J.L.1
Zhao, A.2
Yu, J.3
Huang, L.4
De Pedro, N.5
Pelaez, F.6
Wright, S.D.7
Cui, J.8
-
139
-
-
0037199946
-
Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity
-
Yu, J., J. L. Lo, L. Huang, A. Zhao, E. Metzger, A. Adams, P. T. Meinke, S. D. Wright, and J. Cui. 2002. Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity. J. Biol. Chem. 277: 31441-31447.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 31441-31447
-
-
Yu, J.1
Lo, J.L.2
Huang, L.3
Zhao, A.4
Metzger, E.5
Adams, A.6
Meinke, P.T.7
Wright, S.D.8
Cui, J.9
-
140
-
-
7544221726
-
Detoxification of lithocholic acid, a toxic bile acid: Relevance to drug hepatotoxicity
-
Hofmann, A. F. 2004. Detoxification of lithocholic acid, a toxic bile acid: relevance to drug hepatotoxicity. Drug Metab. Rev. 36: 703-722.
-
(2004)
Drug Metab. Rev
, vol.36
, pp. 703-722
-
-
Hofmann, A.F.1
-
141
-
-
11144227974
-
Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1
-
Ananthanarayanan, M., S. Li, N. Balasubramaniyan, F. J. Suchy, and M. J. Walsh. 2004. Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1. J. Biol. Chem. 279: 54348-54357.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 54348-54357
-
-
Ananthanarayanan, M.1
Li, S.2
Balasubramaniyan, N.3
Suchy, F.J.4
Walsh, M.J.5
-
142
-
-
23044444663
-
The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes
-
Rizzo, G., B. Renga, E. Antonelli, D. Passeri, R. Pellicciari, and S. Fiorucci. 2005. The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes. Mol. Pharmacol. 68: 551-558.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 551-558
-
-
Rizzo, G.1
Renga, B.2
Antonelli, E.3
Passeri, D.4
Pellicciari, R.5
Fiorucci, S.6
-
143
-
-
0038701656
-
Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding
-
Kassam, A., B. Miao, P. R. Young, and R. Mukherjee. 2003. Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding. J. Biol. Chem. 278: 10028-10032.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10028-10032
-
-
Kassam, A.1
Miao, B.2
Young, P.R.3
Mukherjee, R.4
-
144
-
-
58949092547
-
Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters
-
Hoeke, M. O., J. R. Plass, J. Heegsma, M. Geuken, D. van Rijsbergen, J. F. Baller, F. Kuipers, H. Moshage, P. L. Jansen, and K. N. Faber. 2009. Low retinol levels differentially modulate bile salt-induced expression of human and mouse hepatic bile salt transporters. Hepatology. 49: 151-159.
-
(2009)
Hepatology
, vol.49
, pp. 151-159
-
-
Hoeke, M.O.1
Plass, J.R.2
Heegsma, J.3
Geuken, M.4
van Rijsbergen, D.5
Baller, J.F.6
Kuipers, F.7
Moshage, H.8
Jansen, P.L.9
Faber, K.N.10
-
145
-
-
33644859036
-
Hepatocanalicular transport defects: Pathophysiologic mechanisms of rare diseases
-
Oude Elferink, R. P., C. C. Paulusma, and A. K. Groen. 2006. Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases. Gastroenterology. 130: 908-925.
-
(2006)
Gastroenterology
, vol.130
, pp. 908-925
-
-
Oude Elferink, R.P.1
Paulusma, C.C.2
Groen, A.K.3
-
146
-
-
65649087129
-
Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content
-
Paulusma, C. C., D. R. de Waart, C. Kunne, K. S. Mok, and R. P. Elferink. 2009. Activity of the bile salt export pump (ABCB11) is critically dependent on canalicular membrane cholesterol content. J. Biol. Chem. 284: 9947-9954.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 9947-9954
-
-
Paulusma, C.C.1
de Waart, D.R.2
Kunne, C.3
Mok, K.S.4
Elferink, R.P.5
-
148
-
-
60449097716
-
ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained
-
Cai, S. Y., S. Gautam, T. Nguyen, C. J. Soroka, C. Rahner, and J. L. Boyer. 2009. ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained. Gastroenterology. 136: 1060-1069.
-
(2009)
Gastroenterology
, vol.136
, pp. 1060-1069
-
-
Cai, S.Y.1
Gautam, S.2
Nguyen, T.3
Soroka, C.J.4
Rahner, C.5
Boyer, J.L.6
-
149
-
-
0035021435
-
Intestinal bile acid transport: Biology, physiology, and pathophysiology
-
Shneider, B. L. 2001. Intestinal bile acid transport: biology, physiology, and pathophysiology. J. Pediatr. Gastroenterol. Nutr. 32: 407-417.
-
(2001)
J. Pediatr. Gastroenterol. Nutr
, vol.32
, pp. 407-417
-
-
Shneider, B.L.1
-
150
-
-
14844291348
-
The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter
-
Dawson, P. A., M. Hubbert, J. Haywood, A. L. Craddock, N. Zerangue, W. V. Christian, and N. Ballatori. 2005. The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter. J. Biol. Chem. 280: 6960-6968.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 6960-6968
-
-
Dawson, P.A.1
Hubbert, M.2
Haywood, J.3
Craddock, A.L.4
Zerangue, N.5
Christian, W.V.6
Ballatori, N.7
-
151
-
-
30844460667
-
OSTalpha-OSTbeta: A major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia
-
Ballatori, N., W. V. Christian, J. Y. Lee, P. A. Dawson, C. J. Soroka, J. L. Boyer, M. S. Madejczyk, and N. Li. 2005. OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia. Hepatology. 42: 1270-1279.
-
(2005)
Hepatology
, vol.42
, pp. 1270-1279
-
-
Ballatori, N.1
Christian, W.V.2
Lee, J.Y.3
Dawson, P.A.4
Soroka, C.J.5
Boyer, J.L.6
Madejczyk, M.S.7
Li, N.8
-
152
-
-
0015338557
-
Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride
-
Hofmann, A. F., and J. R. Poley. 1972. Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride. Gastroenterology. 62: 918-934.
-
(1972)
Gastroenterology
, vol.62
, pp. 918-934
-
-
Hofmann, A.F.1
Poley, J.R.2
-
153
-
-
0025966034
-
Active absorption of conjugated bile acids in vivo. Kinetic parameters and molecular specificity of the ileal transport system in the rat
-
Marcus, S. N., C. D. Schteingart, M. L. Marquez, A. F. Hofmann, Y. Xia, J. H. Steinbach, H. T. Ton-Nu, J. Lillienau, M. A. Angellotti, and A. Schmassmann. 1991. Active absorption of conjugated bile acids in vivo. Kinetic parameters and molecular specificity of the ileal transport system in the rat. Gastroenterology. 100: 212-221.
-
(1991)
Gastroenterology
, vol.100
, pp. 212-221
-
-
Marcus, S.N.1
Schteingart, C.D.2
Marquez, M.L.3
Hofmann, A.F.4
Xia, Y.5
Steinbach, J.H.6
Ton-Nu, H.T.7
Lillienau, J.8
Angellotti, M.A.9
Schmassmann, A.10
-
154
-
-
0028043625
-
Hepatic uptake and intestinal absorption of bile acids in the rabbit
-
Aldini, R., A. Roda, M. Montagnani, C. Polimeni, P. L. Lenzi, C. Cerre, G. Galletti, and E. Roda. 1994. Hepatic uptake and intestinal absorption of bile acids in the rabbit. Eur. J. Clin. Invest. 24: 691-697.
-
(1994)
Eur. J. Clin. Invest
, vol.24
, pp. 691-697
-
-
Aldini, R.1
Roda, A.2
Montagnani, M.3
Polimeni, C.4
Lenzi, P.L.5
Cerre, C.6
Galletti, G.7
Roda, E.8
-
155
-
-
0030020934
-
Intestinal absorption of bile acids in the rabbit: Different transport rates in jejunum and ileum
-
Aldini, R., M. Montagnani, A. Roda, S. Hrelia, P. L. Biagi, and E. Roda. 1996. Intestinal absorption of bile acids in the rabbit: different transport rates in jejunum and ileum. Gastroenterology. 110: 459-468.
-
(1996)
Gastroenterology
, vol.110
, pp. 459-468
-
-
Aldini, R.1
Montagnani, M.2
Roda, A.3
Hrelia, S.4
Biagi, P.L.5
Roda, E.6
-
156
-
-
3242699674
-
Involvement of mast cells in basal and neurotensin-induced intestinal absorption of taurocholate in rats
-
Gui, X., and R. E. Carraway. 2004. Involvement of mast cells in basal and neurotensin-induced intestinal absorption of taurocholate in rats. Am. J. Physiol. Gastrointest. Liver Physiol. 287: G408-G416.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.287
-
-
Gui, X.1
Carraway, R.E.2
-
157
-
-
0141818009
-
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice
-
Dawson, P. A., J. Haywood, A. L. Craddock, M. Wilson, M. Tietjen, K. Kluckman, N. Maeda, and J. S. Parks. 2003. Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J. Biol. Chem. 278: 33920-33927.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33920-33927
-
-
Dawson, P.A.1
Haywood, J.2
Craddock, A.L.3
Wilson, M.4
Tietjen, M.5
Kluckman, K.6
Maeda, N.7
Parks, J.S.8
-
158
-
-
0020613211
-
Determination of acid surface pH in vivo in rat proximal jejunum
-
Lucas, M. 1983. Determination of acid surface pH in vivo in rat proximal jejunum. Gut. 24: 734-739.
-
(1983)
Gut
, vol.24
, pp. 734-739
-
-
Lucas, M.1
-
159
-
-
0027250469
-
Intestinal bile acid absorption. Na(+)-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93-kDa and a peripheral 14-kDa bile acid-binding membrane protein along the duodenum-ileum axis
-
Kramer, W., F. Girbig, U. Gutjahr, S. Kowalewski, K. Jouvenal, G. Muller, D. Tripier, and G. Wess. 1993. Intestinal bile acid absorption. Na(+)-dependent bile acid transport activity in rabbit small intestine correlates with the coexpression of an integral 93-kDa and a peripheral 14-kDa bile acid-binding membrane protein along the duodenum-ileum axis. J. Biol. Chem. 268: 18035-18046.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 18035-18046
-
-
Kramer, W.1
Girbig, F.2
Gutjahr, U.3
Kowalewski, S.4
Jouvenal, K.5
Muller, G.6
Tripier, D.7
Wess, G.8
-
160
-
-
0030273188
-
Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification
-
Aldini, R., A. Roda, M. Montagnani, C. Cerre, R. Pellicciari, and E. Roda. 1996. Relationship between structure and intestinal absorption of bile acids with a steroid or side-chain modification. Steroids. 61: 590-597.
-
(1996)
Steroids
, vol.61
, pp. 590-597
-
-
Aldini, R.1
Roda, A.2
Montagnani, M.3
Cerre, C.4
Pellicciari, R.5
Roda, E.6
-
161
-
-
0029920858
-
Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig
-
Amelsberg, A., C. D. Schteingart, H. T. Ton-Nu, and A. F. Hofmann. 1996. Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig. Gastroenterology. 110: 1098-1106.
-
(1996)
Gastroenterology
, vol.110
, pp. 1098-1106
-
-
Amelsberg, A.1
Schteingart, C.D.2
Ton-Nu, H.T.3
Hofmann, A.F.4
-
162
-
-
0032925208
-
Evidence for an anion exchange mechanism for uptake of conjugated bile acid from the rat jejunum
-
Amelsberg, A., C. Jochims, C. P. Richter, R. Nitsche, and U. R. Folsch. 1999. Evidence for an anion exchange mechanism for uptake of conjugated bile acid from the rat jejunum. Am. J. Physiol. 276: G737-G742.
-
(1999)
Am. J. Physiol
, vol.276
-
-
Amelsberg, A.1
Jochims, C.2
Richter, C.P.3
Nitsche, R.4
Folsch, U.R.5
-
163
-
-
0033638544
-
Expression, transport properties, and chromosomal location of organic anion transporter subtype 3
-
Walters, H. C., A. L. Craddock, H. Fusegawa, M. C. Willingham, and P. A. Dawson. 2000. Expression, transport properties, and chromosomal location of organic anion transporter subtype 3. Am. J. Physiol. Gastrointest. Liver Physiol. 279: G1188-G1200.
-
(2000)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.279
-
-
Walters, H.C.1
Craddock, A.L.2
Fusegawa, H.3
Willingham, M.C.4
Dawson, P.A.5
-
164
-
-
1242272736
-
Organic anion transporting polypeptides of the OATP/SLC21 family: Phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties
-
Hagenbuch, B., and P. J. Meier. 2004. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch. 447: 653-665.
-
(2004)
Pflugers Arch
, vol.447
, pp. 653-665
-
-
Hagenbuch, B.1
Meier, P.J.2
-
165
-
-
33847662941
-
Intestinal drug transporter expression and the impact of grapefruit juice in humans
-
Glaeser, H., D. G. Bailey, G. K. Dresser, J. C. Gregor, U. I. Schwarz, J. S. McGrath, E. Jolicoeur, W. Lee, B. F. Leake, R. G. Tirona, et al. 2007. Intestinal drug transporter expression and the impact of grapefruit juice in humans. Clin. Pharmacol. Ther. 81: 362-370.
-
(2007)
Clin. Pharmacol. Ther
, vol.81
, pp. 362-370
-
-
Glaeser, H.1
Bailey, D.G.2
Dresser, G.K.3
Gregor, J.C.4
Schwarz, U.I.5
McGrath, J.S.6
Jolicoeur, E.7
Lee, W.8
Leake, B.F.9
Tirona, R.G.10
-
166
-
-
0036159433
-
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine
-
Dresser, G. K., D. G. Bailey, B. F. Leake, U. I. Schwarz, P. A. Dawson, D. J. Freeman, and R. B. Kim. 2002. Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine. Clin. Pharmacol. Ther. 71: 11-20.
-
(2002)
Clin. Pharmacol. Ther
, vol.71
, pp. 11-20
-
-
Dresser, G.K.1
Bailey, D.G.2
Leake, B.F.3
Schwarz, U.I.4
Dawson, P.A.5
Freeman, D.J.6
Kim, R.B.7
-
167
-
-
33847235324
-
Identification of influx transporter for the quinolone antibacterial agent levofloxacin
-
Maeda, T., K. Takahashi, N. Ohtsu, T. Oguma, T. Ohnishi, R. Atsumi, and I. Tamai. 2007. Identification of influx transporter for the quinolone antibacterial agent levofloxacin. Mol. Pharm. 4: 85-94.
-
(2007)
Mol. Pharm
, vol.4
, pp. 85-94
-
-
Maeda, T.1
Takahashi, K.2
Ohtsu, N.3
Oguma, T.4
Ohnishi, T.5
Atsumi, R.6
Tamai, I.7
-
168
-
-
34047170808
-
Regional distribution of solute carrier (SLC) mRNA expression along the human intestinal tract
-
Meier, Y., J. J. Eloranta, J. Darimont, M. G. Ismair, C. Hiller, M. Fried, G. A. Kullak-Ublick, and S. R. Vavricka. 2007. Regional distribution of solute carrier (SLC) mRNA expression along the human intestinal tract. Drug Metab Dispos. 35: 590-594.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 590-594
-
-
Meier, Y.1
Eloranta, J.J.2
Darimont, J.3
Ismair, M.G.4
Hiller, C.5
Fried, M.6
Kullak-Ublick, G.A.7
Vavricka, S.R.8
-
169
-
-
0030944084
-
Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)
-
Oelkers, P., L. C. Kirby, J. E. Heubi, and P. A. Dawson. 1997. Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2). J. Clin. Invest. 99: 1880-1887.
-
(1997)
J. Clin. Invest
, vol.99
, pp. 1880-1887
-
-
Oelkers, P.1
Kirby, L.C.2
Heubi, J.E.3
Dawson, P.A.4
-
170
-
-
51149089559
-
Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver
-
Ballatori, N., F. Fang, W. V. Christian, N. Li, and C. L. Hammond. 2008. Ostalpha-Ostbeta is required for bile acid and conjugated steroid disposition in the intestine, kidney, and liver. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G179-G186.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.295
-
-
Ballatori, N.1
Fang, F.2
Christian, W.V.3
Li, N.4
Hammond, C.L.5
-
171
-
-
41649089141
-
The organic solute transporter alphabeta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis
-
Rao, A., J. Haywood, A. L. Craddock, M. G. Belinsky, G. D. Kruh, and P. A. Dawson. 2008. The organic solute transporter alphabeta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis. Proc. Natl. Acad. Sci. USA. 105: 3891-3896.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 3891-3896
-
-
Rao, A.1
Haywood, J.2
Craddock, A.L.3
Belinsky, M.G.4
Kruh, G.D.5
Dawson, P.A.6
-
172
-
-
42149145538
-
Exploring possible mechanisms for primary bile acid malabsorption: Evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea
-
Balesaria, S., R. J. Pell, L. J. Abbott, A. Tasleem, K. M. Chavele, N. F. Barley, U. Khair, A. Simon, K. J. Moriarty, W. G. Brydon, et al. 2008. Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. Eur. J. Gastroenterol. Hepatol. 20: 413-422.
-
(2008)
Eur. J. Gastroenterol. Hepatol
, vol.20
, pp. 413-422
-
-
Balesaria, S.1
Pell, R.J.2
Abbott, L.J.3
Tasleem, A.4
Chavele, K.M.5
Barley, N.F.6
Khair, U.7
Simon, A.8
Moriarty, K.J.9
Brydon, W.G.10
-
173
-
-
0032567523
-
Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic
-
Weinman, S. A., M. W. Carruth, and P. A. Dawson. 1998. Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic. J. Biol. Chem. 273: 34691-34695.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 34691-34695
-
-
Weinman, S.A.1
Carruth, M.W.2
Dawson, P.A.3
-
174
-
-
0028800562
-
Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter
-
Shneider, B. L., P. A. Dawson, D. M. Christie, W. Hardikar, M. H. Wong, and F. J. Suchy. 1995. Cloning and molecular characterization of the ontogeny of a rat ileal sodium-dependent bile acid transporter. J. Clin. Invest. 95: 745-754.
-
(1995)
J. Clin. Invest
, vol.95
, pp. 745-754
-
-
Shneider, B.L.1
Dawson, P.A.2
Christie, D.M.3
Hardikar, W.4
Wong, M.H.5
Suchy, F.J.6
-
175
-
-
0028039878
-
Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter
-
Wong, M. H., P. Oelkers, A. L. Craddock, and P. A. Dawson. 1994. Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter. J. Biol. Chem. 269: 1340-1347.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 1340-1347
-
-
Wong, M.H.1
Oelkers, P.2
Craddock, A.L.3
Dawson, P.A.4
-
176
-
-
0029792840
-
Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum
-
Christie, D. M., P. A. Dawson, S. Thevananther, and B. L. Shneider. 1996. Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum. Am. J. Physiol. 271: G377-G385.
-
(1996)
Am. J. Physiol
, vol.271
-
-
Christie, D.M.1
Dawson, P.A.2
Thevananther, S.3
Shneider, B.L.4
-
177
-
-
0030832592
-
+-dependent bile acid transporter in large but not small rat cholangiocytes
-
+-dependent bile acid transporter in large but not small rat cholangiocytes. Gastroenterology. 113: 1734-1740.
-
(1997)
Gastroenterology
, vol.113
, pp. 1734-1740
-
-
Alpini, G.1
Glaser, S.S.2
Rodgers, R.3
Phinizy, J.L.4
Robertson, W.E.5
Lasater, J.6
Caligiuri, A.7
Tretjak, Z.8
LeSage, G.D.9
-
178
-
-
0031467883
-
Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter
-
Lazaridis, K., L. Pham, P. Tietz, R. Marinelli, P. deGroen, S. Levine, P. Dawson, and N. LaRusso. 1997. Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter. J. Clin. Invest. 100: 2714-2721.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 2714-2721
-
-
Lazaridis, K.1
Pham, L.2
Tietz, P.3
Marinelli, R.4
deGroen, P.5
Levine, S.6
Dawson, P.7
LaRusso, N.8
-
179
-
-
0035123566
-
Bile acid transport and regulating functions in the human biliary epithelium
-
Chignard, N., M. Mergey, D. Veissiere, R. Parc, J. Capeau, R. Poupon, A. Paul, and C. Housset. 2001. Bile acid transport and regulating functions in the human biliary epithelium. Hepatology. 33: 496-503.
-
(2001)
Hepatology
, vol.33
, pp. 496-503
-
-
Chignard, N.1
Mergey, M.2
Veissiere, D.3
Parc, R.4
Capeau, J.5
Poupon, R.6
Paul, A.7
Housset, C.8
-
180
-
-
0024239734
-
Active absorption of vitamin B12 and conjugated bile salts by guinea pig ileum occurs in villous and not crypt cells
-
Kapadia, C. R., and L. K. Essandoh. 1988. Active absorption of vitamin B12 and conjugated bile salts by guinea pig ileum occurs in villous and not crypt cells. Dig. Dis. Sci. 33: 1377-1382.
-
(1988)
Dig. Dis. Sci
, vol.33
, pp. 1377-1382
-
-
Kapadia, C.R.1
Essandoh, L.K.2
-
181
-
-
0032961354
-
Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter
-
Saeki, T., K. Matoba, H. Furukawa, K. Kirifuji, R. Kanamoto, and K. Iwami. 1999. Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter. J. Biochem. 125: 846-851.
-
(1999)
J. Biochem
, vol.125
, pp. 846-851
-
-
Saeki, T.1
Matoba, K.2
Furukawa, H.3
Kirifuji, K.4
Kanamoto, R.5
Iwami, K.6
-
182
-
-
0036742375
-
Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice
-
Hakansson, P., I. Andersson, S. Nystrom, L. Lofgren, L. F. Amrot, and H. Li. 2002. Ontogenetic development and spatial distribution of the ileal apical sodium-dependent bile acid transporter and the ileal lipid-binding protein in apoE knockout and C57BL/6 mice. Scand. J. Gastroenterol. 37: 1089-1096.
-
(2002)
Scand. J. Gastroenterol
, vol.37
, pp. 1089-1096
-
-
Hakansson, P.1
Andersson, I.2
Nystrom, S.3
Lofgren, L.4
Amrot, L.F.5
Li, H.6
-
183
-
-
0034062956
-
Distribution of bile acid absorption and bile acid transporter gene message in the hamster ileum
-
Stelzner, M., V. Hoagland, and S. Somasundaram. 2000. Distribution of bile acid absorption and bile acid transporter gene message in the hamster ileum. Pflugers Arch. 440: 157-162.
-
(2000)
Pflugers Arch
, vol.440
, pp. 157-162
-
-
Stelzner, M.1
Hoagland, V.2
Somasundaram, S.3
-
184
-
-
0010552586
-
Distribution of bile acid transport capacities in the human ileum (abstract)
-
Stelzner, M., S. Somasundaram, and D. Kearney. 2000. Distribution of bile acid transport capacities in the human ileum (abstract). Gastroenterology. 118: A77.
-
(2000)
Gastroenterology
, vol.118
-
-
Stelzner, M.1
Somasundaram, S.2
Kearney, D.3
-
185
-
-
0031732519
-
Molecular analysis of the adaptive response of intestinal bile acid transport after ileal resection
-
Coppola, C. P., J. R. Gosche, M. Arrese, B. Ancowitz, J. Madsen, J. Vanderhoof, and B. L. Shneider. 1998. Molecular analysis of the adaptive response of intestinal bile acid transport after ileal resection. Gastroenterology. 115: 1172-1178.
-
(1998)
Gastroenterology
, vol.115
, pp. 1172-1178
-
-
Coppola, C.P.1
Gosche, J.R.2
Arrese, M.3
Ancowitz, B.4
Madsen, J.5
Vanderhoof, J.6
Shneider, B.L.7
-
186
-
-
33845191713
-
Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine
-
Bosse, T., C. M. Piaseckyj, E. Burghard, J. J. Fialkovich, S. Rajagopal, W. T. Pu, and S. D. Krasinski. 2006. Gata4 is essential for the maintenance of jejunal-ileal identities in the adult mouse small intestine. Mol. Cell. Biol. 26: 9060-9070.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 9060-9070
-
-
Bosse, T.1
Piaseckyj, C.M.2
Burghard, E.3
Fialkovich, J.J.4
Rajagopal, S.5
Pu, W.T.6
Krasinski, S.D.7
-
187
-
-
55249123809
-
GATA4 is essential for jejunal function in mice
-
Battle, M. A., B. J. Bondow, M. A. Iverson, S. J. Adams, R. J. Jandacek, P. Tso, and S. A. Duncan. 2008. GATA4 is essential for jejunal function in mice. Gastroenterology. 135: 1676-1686.
-
(2008)
Gastroenterology
, vol.135
, pp. 1676-1686
-
-
Battle, M.A.1
Bondow, B.J.2
Iverson, M.A.3
Adams, S.J.4
Jandacek, R.J.5
Tso, P.6
Duncan, S.A.7
-
188
-
-
85047685788
-
Analysis of the effect of intestinal resection on rat ileal bile acid transporter expression and on bile acid and cholesterol homeostasis
-
Al-Ansari, N., G. Xu, K. Kollman-Bauerly, C. Coppola, S. Shefer, P. Ujhazy, D. Ortiz, L. Ma, S. Yang, R. Tsai, et al. 2002. Analysis of the effect of intestinal resection on rat ileal bile acid transporter expression and on bile acid and cholesterol homeostasis. Pediatr. Res. 52: 286-291.
-
(2002)
Pediatr. Res
, vol.52
, pp. 286-291
-
-
Al-Ansari, N.1
Xu, G.2
Kollman-Bauerly, K.3
Coppola, C.4
Shefer, S.5
Ujhazy, P.6
Ortiz, D.7
Ma, L.8
Yang, S.9
Tsai, R.10
-
189
-
-
0029862132
-
Ileal transposition into the upper jejunum affects lipid and bile salt absorption in rats
-
Tsuchiya, T., T. J. Kalogeris, and P. Tso. 1996. Ileal transposition into the upper jejunum affects lipid and bile salt absorption in rats. Am. J. Physiol. 271: G681-G691.
-
(1996)
Am. J. Physiol
, vol.271
-
-
Tsuchiya, T.1
Kalogeris, T.J.2
Tso, P.3
-
190
-
-
0034878273
-
Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption
-
Montagnani, M., M. W. Love, P. Rossel, P. A. Dawson, and P. Qvist. 2001. Absence of dysfunctional ileal sodium-bile acid cotransporter gene mutations in patients with adult-onset idiopathic bile acid malabsorption. Scand. J. Gastroenterol. 36: 1077-1080.
-
(2001)
Scand. J. Gastroenterol
, vol.36
, pp. 1077-1080
-
-
Montagnani, M.1
Love, M.W.2
Rossel, P.3
Dawson, P.A.4
Qvist, P.5
-
191
-
-
67349228148
-
-
Renner, O., S. Harsch, E. Schaeffeler, M. Schwab, D. M. Klass, W. Kratzer, and E. F. Stange. 2009. Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identifi ed variants linked to reduced expression. Hum. Genet. 125: 381-391.
-
Renner, O., S. Harsch, E. Schaeffeler, M. Schwab, D. M. Klass, W. Kratzer, and E. F. Stange. 2009. Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identifi ed variants linked to reduced expression. Hum. Genet. 125: 381-391.
-
-
-
-
192
-
-
0035572837
-
Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia
-
Love, M. W., A. L. Craddock, B. Angelin, J. D. Brunzell, W. C. Duane, and P. A. Dawson. 2001. Analysis of the ileal bile acid transporter gene, SLC10A2, in subjects with familial hypertriglyceridemia. Arterioscler. Thromb. Vasc. Biol. 21: 2039-2045.
-
(2001)
Arterioscler. Thromb. Vasc. Biol
, vol.21
, pp. 2039-2045
-
-
Love, M.W.1
Craddock, A.L.2
Angelin, B.3
Brunzell, J.D.4
Duane, W.C.5
Dawson, P.A.6
-
193
-
-
0033797032
-
Diminished gene expression of ileal apical sodium bile acid transporter explains impaired absorption of bile acid in patients with hypertriglyceridemia
-
Duane, W. C., L. A. Hartich, A. E. Bartman, and S. B. Ho. 2000. Diminished gene expression of ileal apical sodium bile acid transporter explains impaired absorption of bile acid in patients with hypertriglyceridemia. J. Lipid Res. 41: 1384-1389.
-
(2000)
J. Lipid Res
, vol.41
, pp. 1384-1389
-
-
Duane, W.C.1
Hartich, L.A.2
Bartman, A.E.3
Ho, S.B.4
-
194
-
-
0023233054
-
Studies of the prevalence and signifi cance of radiolabeled bile acid malabsorption in a group of patients with idiopathic chronic diarrhea
-
Schiller, L. R., R. B. Hogan, S. G. Morawski, C. A. Santa Ana, M. J. Bern, R. P. Norgaard, G. W. Bo-Linn, and J. S. Fordtran. 1987. Studies of the prevalence and signifi cance of radiolabeled bile acid malabsorption in a group of patients with idiopathic chronic diarrhea. Gastroenterology. 92: 151-160.
-
(1987)
Gastroenterology
, vol.92
, pp. 151-160
-
-
Schiller, L.R.1
Hogan, R.B.2
Morawski, S.G.3
Santa Ana, C.A.4
Bern, M.J.5
Norgaard, R.P.6
Bo-Linn, G.W.7
Fordtran, J.S.8
-
195
-
-
0014254324
-
Bile salt malabsorption in regional ileitis, ileal resection and mannitol-induced diarrhea
-
Meihoff, W. E., and F. Kern, Jr. 1968. Bile salt malabsorption in regional ileitis, ileal resection and mannitol-induced diarrhea. J. Clin. Invest. 47: 261-267.
-
(1968)
J. Clin. Invest
, vol.47
, pp. 261-267
-
-
Meihoff, W.E.1
Kern Jr., F.2
-
196
-
-
0042834374
-
Enterohepatic cycling of bilirubin as a cause of 'black' pigment gallstones in adult life
-
Vitek, L., and M. C. Carey. 2003. Enterohepatic cycling of bilirubin as a cause of 'black' pigment gallstones in adult life. Eur. J. Clin. Invest. 33: 799-810.
-
(2003)
Eur. J. Clin. Invest
, vol.33
, pp. 799-810
-
-
Vitek, L.1
Carey, M.C.2
-
197
-
-
52849088394
-
Diminished expression of apical sodium-dependent bile acid transporter in gallstone disease is independent of ileal inflammation
-
Holzer, A., S. Harsch, O. Renner, A. Strohmeyer, S. Schimmel, J. Wehkamp, P. Fritz, and E. F. Stange. 2008. Diminished expression of apical sodium-dependent bile acid transporter in gallstone disease is independent of ileal inflammation. Digestion. 78: 52-59.
-
(2008)
Digestion
, vol.78
, pp. 52-59
-
-
Holzer, A.1
Harsch, S.2
Renner, O.3
Strohmeyer, A.4
Schimmel, S.5
Wehkamp, J.6
Fritz, P.7
Stange, E.F.8
-
198
-
-
0027977042
-
Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT
-
Nyhlin, H., M. Merrick, and M. Eastwood. 1994. Bile acid malabsorption in Crohn's disease and indications for its assessment using SeHCAT. Gut. 35: 90-93.
-
(1994)
Gut
, vol.35
, pp. 90-93
-
-
Nyhlin, H.1
Merrick, M.2
Eastwood, M.3
-
199
-
-
0017081286
-
Regional ileitis (Crohn's disease): I. Kinetics of bile acid absorption in the perfused ileum
-
Krag, B., and B. Krag. 1976. Regional ileitis (Crohn's disease): I. Kinetics of bile acid absorption in the perfused ileum. Scand. J. Gastroenterol. 11: 481-486.
-
(1976)
Scand. J. Gastroenterol
, vol.11
, pp. 481-486
-
-
Krag, B.1
Krag, B.2
-
200
-
-
0018843090
-
Tests of bile-acid and vitamin B 12 metabolism in ileal crohn's disease
-
Farivar, S., H. Fromm, D. Schindler, B. McJunkin, and F. Schmidt. 1980. Tests of bile-acid and vitamin B 12 metabolism in ileal crohn's disease. Am. J. Clin. Pathol. 73: 69-74.
-
(1980)
Am. J. Clin. Pathol
, vol.73
, pp. 69-74
-
-
Farivar, S.1
Fromm, H.2
Schindler, D.3
McJunkin, B.4
Schmidt, F.5
-
201
-
-
0022462290
-
Bile acid metabolism in patients with Crohn's disease in terminal ileum
-
Tougaard, L., B. Giese, B. Pedersen, and V. Binder. 1986. Bile acid metabolism in patients with Crohn's disease in terminal ileum. Scand. J. Gastroenterol. 21: 627-633.
-
(1986)
Scand. J. Gastroenterol
, vol.21
, pp. 627-633
-
-
Tougaard, L.1
Giese, B.2
Pedersen, B.3
Binder, V.4
-
202
-
-
0031934798
-
Intestinal absorption of ursodeoxycholic acid in children and adolescents with inflammatory bowel disease
-
Fujisawa, T., A. Kimura, K. Ushijima, E. Nakashima, T. Inoue, Y. Yamashita, and H. Kato. 1998. Intestinal absorption of ursodeoxycholic acid in children and adolescents with inflammatory bowel disease. J. Pediatr. Gastroenterol. Nutr. 26: 279-285.
-
(1998)
J. Pediatr. Gastroenterol. Nutr
, vol.26
, pp. 279-285
-
-
Fujisawa, T.1
Kimura, A.2
Ushijima, K.3
Nakashima, E.4
Inoue, T.5
Yamashita, Y.6
Kato, H.7
-
203
-
-
67650480494
-
-
Camilleri, M., A. Nadeau, W. J. Tremaine, J. Lamsam, D. Burton, S. Odunsi, S. Sweetser, and R. Singh. 2009. Measurement of serum 7alpha-hydroxy-4-cholesten-3-one (or 7alphaC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry. Neurogastroenterol Motil. 21: 734-e43.
-
Camilleri, M., A. Nadeau, W. J. Tremaine, J. Lamsam, D. Burton, S. Odunsi, S. Sweetser, and R. Singh. 2009. Measurement of serum 7alpha-hydroxy-4-cholesten-3-one (or 7alphaC4), a surrogate test for bile acid malabsorption in health, ileal disease and irritable bowel syndrome using liquid chromatography-tandem mass spectrometry. Neurogastroenterol Motil. 21: 734-e43.
-
-
-
-
204
-
-
0027977645
-
Downregulation of taurocholate transport by ileal BBM and liver BLM in biliary-diverted rats
-
Higgins, J. V., J. M. Paul, R. Dumaswala, and J. E. Heubi. 1994. Downregulation of taurocholate transport by ileal BBM and liver BLM in biliary-diverted rats. Am. J. Physiol. 267: G501-G507.
-
(1994)
Am. J. Physiol
, vol.267
-
-
Higgins, J.V.1
Paul, J.M.2
Dumaswala, R.3
Heubi, J.E.4
-
205
-
-
0027404152
-
Negative feedback regulation of the ileal bile acid transport system in rodents
-
Lillienau, J., D. L. Crombie, J. Munoz, S. J. Longmire-Cook, L. R. Hagey, and A. F. Hofmann. 1993. Negative feedback regulation of the ileal bile acid transport system in rodents. Gastroenterology. 104: 38-46.
-
(1993)
Gastroenterology
, vol.104
, pp. 38-46
-
-
Lillienau, J.1
Crombie, D.L.2
Munoz, J.3
Longmire-Cook, S.J.4
Hagey, L.R.5
Hofmann, A.F.6
-
206
-
-
0030781406
-
Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid
-
Stravitz, R. T., A. J. Sanyal, W. M. Pandak, Z. R. Vlahcevic, J. W. Beets, and P. A. Dawson. 1997. Induction of sodium-dependent bile acid transporter messenger RNA, protein, and activity in rat ileum by cholic acid. Gastroenterology. 113: 1599-1608.
-
(1997)
Gastroenterology
, vol.113
, pp. 1599-1608
-
-
Stravitz, R.T.1
Sanyal, A.J.2
Pandak, W.M.3
Vlahcevic, Z.R.4
Beets, J.W.5
Dawson, P.A.6
-
207
-
-
0031682708
-
Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter
-
Arrese, M., M. Trauner, R. J. Sacchiero, M. W. Crossman, and B. L. Shneider. 1998. Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter. Hepatology. 28: 1081-1087.
-
(1998)
Hepatology
, vol.28
, pp. 1081-1087
-
-
Arrese, M.1
Trauner, M.2
Sacchiero, R.J.3
Crossman, M.W.4
Shneider, B.L.5
-
208
-
-
36749080990
-
Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene
-
Duane, W. C., W. Xiong, and J. Wolvers. 2007. Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene. Biochim. Biophys. Acta. 1771: 1380-1388.
-
(2007)
Biochim. Biophys. Acta
, vol.1771
, pp. 1380-1388
-
-
Duane, W.C.1
Xiong, W.2
Wolvers, J.3
-
209
-
-
85046518258
-
Regulation of ileal bile acid transport: Desirability of measuring transport function as well as transporter activity
-
Hofmann, A. F. 1999. Regulation of ileal bile acid transport: desirability of measuring transport function as well as transporter activity. Hepatology. 29: 1335-1337.
-
(1999)
Hepatology
, vol.29
, pp. 1335-1337
-
-
Hofmann, A.F.1
-
210
-
-
0037827787
-
Liver receptor homologue-1 mediates species- and cell linespecific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter
-
Chen, F., L. Ma, P. A. Dawson, C. J. Sinal, E. Sehayek, F. J. Gonzalez, J. Breslow, M. Ananthanarayanan, and B. L. Shneider. 2003. Liver receptor homologue-1 mediates species- and cell linespecific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter. J. Biol. Chem. 278: 19909-19916.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 19909-19916
-
-
Chen, F.1
Ma, L.2
Dawson, P.A.3
Sinal, C.J.4
Sehayek, E.5
Gonzalez, F.J.6
Breslow, J.7
Ananthanarayanan, M.8
Shneider, B.L.9
-
211
-
-
10844287785
-
FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade
-
Li, H., F. Chen, Q. Shang, L. Pan, B. L. Shneider, J. Y. Chiang, B. M. Forman, M. Ananthanarayanan, G. S. Tint, G. Salen, et al. 2005. FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G60-G66.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
-
-
Li, H.1
Chen, F.2
Shang, Q.3
Pan, L.4
Shneider, B.L.5
Chiang, J.Y.6
Forman, B.M.7
Ananthanarayanan, M.8
Tint, G.S.9
Salen, G.10
-
212
-
-
0142211282
-
Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: Efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein
-
Kok, T., C. V. Hulzebos, H. Wolters, R. Havinga, L. B. Agellon, F. Stellaard, B. Shan, M. Schwarz, and F. Kuipers. 2003. Enterohepatic circulation of bile salts in farnesoid X receptor-deficient mice: efficient intestinal bile salt absorption in the absence of ileal bile acid-binding protein. J. Biol. Chem. 278: 41930-41937.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 41930-41937
-
-
Kok, T.1
Hulzebos, C.V.2
Wolters, H.3
Havinga, R.4
Agellon, L.B.5
Stellaard, F.6
Shan, B.7
Schwarz, M.8
Kuipers, F.9
-
213
-
-
33645807863
-
Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids
-
Frankenberg, T., A. Rao, F. Chen, J. Haywood, B. L. Shneider, and P. A. Dawson. 2006. Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G912-G922.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Frankenberg, T.1
Rao, A.2
Chen, F.3
Haywood, J.4
Shneider, B.L.5
Dawson, P.A.6
-
214
-
-
3042828426
-
Bile acid-induced negative feedback regulation of the human ileal bile acid transporter
-
Neimark, E., F. Chen, X. Li, and B. L. Shneider. 2004. Bile acid-induced negative feedback regulation of the human ileal bile acid transporter. Hepatology. 40: 149-156.
-
(2004)
Hepatology
, vol.40
, pp. 149-156
-
-
Neimark, E.1
Chen, F.2
Li, X.3
Shneider, B.L.4
-
215
-
-
0042508785
-
Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration
-
Lanzini, A., M. G. De Tavonatti, B. Panarotto, S. Scalia, A. Mora, F. Benini, O. Baisini, and F. Lanzarotto. 2003. Intestinal absorption of the bile acid analogue 75Se-homocholic acid-taurine is increased in primary biliary cirrhosis, and reverts to normal during ursodeoxycholic acid administration. Gut. 52: 1371-1375.
-
(2003)
Gut
, vol.52
, pp. 1371-1375
-
-
Lanzini, A.1
De Tavonatti, M.G.2
Panarotto, B.3
Scalia, S.4
Mora, A.5
Benini, F.6
Baisini, O.7
Lanzarotto, F.8
-
216
-
-
33244460809
-
Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis
-
Hruz, P., C. Zimmermann, H. Gutmann, L. Degen, U. Beuers, L. Terracciano, J. Drewe, and C. Beglinger. 2006. Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis. Gut. 55: 395-402.
-
(2006)
Gut
, vol.55
, pp. 395-402
-
-
Hruz, P.1
Zimmermann, C.2
Gutmann, H.3
Degen, L.4
Beuers, U.5
Terracciano, L.6
Drewe, J.7
Beglinger, C.8
-
217
-
-
57349124804
-
Beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes
-
Sinha, J., F. Chen, T. Miloh, R. C. Burns, Z. Yu, and B. L. Shneider. 2008. Beta-Klotho and FGF-15/19 inhibit the apical sodium-dependent bile acid transporter in enterocytes and cholangiocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 295: G996-G1003.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.295
-
-
Sinha, J.1
Chen, F.2
Miloh, T.3
Burns, R.C.4
Yu, Z.5
Shneider, B.L.6
-
218
-
-
65249104853
-
Bile acid signaling pathways increase stability of small heterodimer partner (SHP) by inhibiting ubiquitin-proteasomal degradation
-
Miao, J., Z. Xiao, D. Kanamaluru, G. Min, P. M. Yau, T. D. Veenstra, E. Ellis, S. Strom, K. Suino-Powell, H. E. Xu, et al. 2009. Bile acid signaling pathways increase stability of small heterodimer partner (SHP) by inhibiting ubiquitin-proteasomal degradation. Genes Dev. 23: 986-996.
-
(2009)
Genes Dev
, vol.23
, pp. 986-996
-
-
Miao, J.1
Xiao, Z.2
Kanamaluru, D.3
Min, G.4
Yau, P.M.5
Veenstra, T.D.6
Ellis, E.7
Strom, S.8
Suino-Powell, K.9
Xu, H.E.10
-
219
-
-
17644373075
-
Cholesterol modulates human intestinal sodium-dependent bile acid transporter
-
Alrefai, W. A., Z. Sarwar, S. Tyagi, S. Saksena, P. K. Dudeja, and R. K. Gill. 2005. Cholesterol modulates human intestinal sodium-dependent bile acid transporter. Am. J. Physiol. Gastrointest. Liver Physiol. 288: G978-G985.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
-
-
Alrefai, W.A.1
Sarwar, Z.2
Tyagi, S.3
Saksena, S.4
Dudeja, P.K.5
Gill, R.K.6
-
220
-
-
33747798368
-
Cholesterol dependent down-regulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: Molecular mechanism and physiological consequences
-
Thomas, C., J. F. Landrier, D. Gaillard, J. Grober, M. C. Monnot, A. Athias, and P. Besnard. 2006. Cholesterol dependent down-regulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences. Gut. 55: 1321-1331.
-
(2006)
Gut
, vol.55
, pp. 1321-1331
-
-
Thomas, C.1
Landrier, J.F.2
Gaillard, D.3
Grober, J.4
Monnot, M.C.5
Athias, A.6
Besnard, P.7
-
221
-
-
59649099592
-
Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption
-
Miyata, M., Y. Matsuda, M. Nomoto, Y. Takamatsu, N. Sato, M. Hamatsu, P. A. Dawson, F. J. Gonzalez, and Y. Yamazoe. 2009. Cholesterol feeding prevents hepatic accumulation of bile acids in cholic acid-fed farnesoid X receptor (FXR)-null mice: FXR-independent suppression of intestinal bile acid absorption. Drug Metab. Dispos. 37: 338-344.
-
(2009)
Drug Metab. Dispos
, vol.37
, pp. 338-344
-
-
Miyata, M.1
Matsuda, Y.2
Nomoto, M.3
Takamatsu, Y.4
Sato, N.5
Hamatsu, M.6
Dawson, P.A.7
Gonzalez, F.J.8
Yamazoe, Y.9
-
222
-
-
0034894970
-
Systemic effects of acute terminal ileitis on uninflamed gut aggravate bile acid malabsorption
-
Stelzner, M., S. Somasundaram, and T. Khakberdiev. 2001. Systemic effects of acute terminal ileitis on uninflamed gut aggravate bile acid malabsorption. J. Surg. Res. 99: 359-364.
-
(2001)
J. Surg. Res
, vol.99
, pp. 359-364
-
-
Stelzner, M.1
Somasundaram, S.2
Khakberdiev, T.3
-
223
-
-
0346607187
-
Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor
-
Jung, D., A. C. Fantin, U. Scheurer, M. Fried, and G. A. Kullak-Ublick. 2004. Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor. Gut. 53: 78-84.
-
(2004)
Gut
, vol.53
, pp. 78-84
-
-
Jung, D.1
Fantin, A.C.2
Scheurer, U.3
Fried, M.4
Kullak-Ublick, G.A.5
-
224
-
-
0035914393
-
The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter
-
Chen, F., L. Ma, N. Al-Ansari, and B. Shneider. 2001. The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter. J. Biol. Chem. 276: 38703-38714.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 38703-38714
-
-
Chen, F.1
Ma, L.2
Al-Ansari, N.3
Shneider, B.4
-
225
-
-
0036892294
-
Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation
-
Chen, F., L. Ma, R. B. Sartor, F. Li, H. Xiong, A. Q. Sun, and B. Shneider. 2002. Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation. Gastroenterology. 123: 2005-2016.
-
(2002)
Gastroenterology
, vol.123
, pp. 2005-2016
-
-
Chen, F.1
Ma, L.2
Sartor, R.B.3
Li, F.4
Xiong, H.5
Sun, A.Q.6
Shneider, B.7
-
226
-
-
0030767968
-
Glucorticoids up-regulate taurocholate transport by the ileal brush border membrane
-
Nowicki, M., B. Shneider, J. Paul, and J. Heubi. 1997. Glucorticoids up-regulate taurocholate transport by the ileal brush border membrane. Am. J. Physiol. 273: G197-G203.
-
(1997)
Am. J. Physiol
, vol.273
-
-
Nowicki, M.1
Shneider, B.2
Paul, J.3
Heubi, J.4
-
227
-
-
0346461667
-
Do steroids ameliorate bile acid malabsorption in Crohn's disease?
-
Kwon, R. S., and M. C. Carey. 2004. Do steroids ameliorate bile acid malabsorption in Crohn's disease? Gut. 53: 10-11.
-
(2004)
Gut
, vol.53
, pp. 10-11
-
-
Kwon, R.S.1
Carey, M.C.2
-
228
-
-
0037163053
-
Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha
-
Jung, D., M. Fried, and G. A. Kullak-Ublick. 2002. Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha. J. Biol. Chem. 277: 30559-30566.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 30559-30566
-
-
Jung, D.1
Fried, M.2
Kullak-Ublick, G.A.3
-
229
-
-
33745122240
-
Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor
-
Chen, X., F. Chen, S. Liu, H. Glaeser, P. A. Dawson, A. F. Hofmann, R. B. Kim, B. L. Shneider, and K. S. Pang. 2006. Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor. Mol. Pharmacol. 69: 1913-1923.
-
(2006)
Mol. Pharmacol
, vol.69
, pp. 1913-1923
-
-
Chen, X.1
Chen, F.2
Liu, S.3
Glaeser, H.4
Dawson, P.A.5
Hofmann, A.F.6
Kim, R.B.7
Shneider, B.L.8
Pang, K.S.9
-
230
-
-
39149141566
-
Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: Association with lipid rafts
-
Annaba, F., Z. Sarwar, P. Kumar, S. Saksena, J. R. Turner, P. K. Dudeja, R. K. Gill, and W. A. Alrefai. 2008. Modulation of ileal bile acid transporter (ASBT) activity by depletion of plasma membrane cholesterol: association with lipid rafts. Am. J. Physiol. Gastrointest. Liver Physiol. 294: G489-G497.
-
(2008)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.294
-
-
Annaba, F.1
Sarwar, Z.2
Kumar, P.3
Saksena, S.4
Turner, J.R.5
Dudeja, P.K.6
Gill, R.K.7
Alrefai, W.A.8
-
231
-
-
7244253050
-
Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes
-
Xia, X., M. Roundtree, A. Merikhi, X. Lu, S. Shentu, and G. Lesage. 2004. Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes. J. Biol. Chem. 279: 44931-44937.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 44931-44937
-
-
Xia, X.1
Roundtree, M.2
Merikhi, A.3
Lu, X.4
Shentu, S.5
Lesage, G.6
-
232
-
-
0022483282
-
Taurocholate transport by rat intestinal basolateral membrane vesicles. Evidence for the presence of an anion exchange transport system
-
Weinberg, S. L., G. Burckhardt, and F. A. Wilson. 1986. Taurocholate transport by rat intestinal basolateral membrane vesicles. Evidence for the presence of an anion exchange transport system. J. Clin. Invest. 78: 44-50.
-
(1986)
J. Clin. Invest
, vol.78
, pp. 44-50
-
-
Weinberg, S.L.1
Burckhardt, G.2
Wilson, F.A.3
-
233
-
-
0024120055
-
Identification and comparison of bile acid-binding polypeptides in ileal basolateral membrane
-
Lin, M. C., S. L. Weinberg, W. Kramer, G. Burckhardt, and F. A. Wilson. 1988. Identification and comparison of bile acid-binding polypeptides in ileal basolateral membrane. J. Membr. Biol. 106: 1-11.
-
(1988)
J. Membr. Biol
, vol.106
, pp. 1-11
-
-
Lin, M.C.1
Weinberg, S.L.2
Kramer, W.3
Burckhardt, G.4
Wilson, F.A.5
-
234
-
-
0034718614
-
Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties
-
Lazaridis, K. N., P. Tietz, T. Wu, S. Kip, P. A. Dawson, and N. F. LaRusso. 2000. Alternative splicing of the rat sodium/bile acid transporter changes its cellular localization and transport properties. Proc. Natl. Acad. Sci. USA. 97: 11092-11097.
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11092-11097
-
-
Lazaridis, K.N.1
Tietz, P.2
Wu, T.3
Kip, S.4
Dawson, P.A.5
LaRusso, N.F.6
-
235
-
-
0345724724
-
The MRP family of drug effl ux pumps
-
Kruh, G. D., and M. G. Belinsky. 2003. The MRP family of drug effl ux pumps. Oncogene. 22: 7537-7552.
-
(2003)
Oncogene
, vol.22
, pp. 7537-7552
-
-
Kruh, G.D.1
Belinsky, M.G.2
-
236
-
-
22344446049
-
Analysis of the in vivo functions of Mrp3
-
Belinsky, M. G., P. A. Dawson, I. Shchaveleva, L. J. Bain, R. Wang, V. Ling, Z. S. Chen, A. Grinberg, H. Westphal, A. Klein-Szanto, et al. 2005. Analysis of the in vivo functions of Mrp3. Mol. Pharmacol. 68: 160-168.
-
(2005)
Mol. Pharmacol
, vol.68
, pp. 160-168
-
-
Belinsky, M.G.1
Dawson, P.A.2
Shchaveleva, I.3
Bain, L.J.4
Wang, R.5
Ling, V.6
Chen, Z.S.7
Grinberg, A.8
Westphal, H.9
Klein-Szanto, A.10
-
237
-
-
33644910207
-
Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides
-
Zelcer, N., K. van de Wetering, R. de Waart, G. L. Scheffer, H. U. Marschall, P. R. Wielinga, A. Kuil, C. Kunne, A. Smith, M. van der Valk, et al. 2006. Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides. J. Hepatol. 44: 768-775.
-
(2006)
J. Hepatol
, vol.44
, pp. 768-775
-
-
Zelcer, N.1
van de Wetering, K.2
de Waart, R.3
Scheffer, G.L.4
Marschall, H.U.5
Wielinga, P.R.6
Kuil, A.7
Kunne, C.8
Smith, A.9
van der Valk, M.10
-
238
-
-
0035979303
-
Expression cloning of two genes that together mediate organic solute and steroid transport in the liver of a marine vertebrate
-
Wang, W., D. J. Seward, L. Li, J. L. Boyer, and N. Ballatori. 2001. Expression cloning of two genes that together mediate organic solute and steroid transport in the liver of a marine vertebrate. Proc. Natl. Acad. Sci. USA. 98: 9431-9436.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9431-9436
-
-
Wang, W.1
Seward, D.J.2
Li, L.3
Boyer, J.L.4
Ballatori, N.5
-
239
-
-
0041344702
-
Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta
-
Seward, D. J., A. S. Koh, J. L. Boyer, and N. Ballatori. 2003. Functional complementation between a novel mammalian polygenic transport complex and an evolutionarily ancient organic solute transporter, OSTalpha-OSTbeta. J. Biol. Chem. 278: 27473-27482.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 27473-27482
-
-
Seward, D.J.1
Koh, A.S.2
Boyer, J.L.3
Ballatori, N.4
-
240
-
-
33644979579
-
The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes
-
Landrier, J. F., J. J. Eloranta, S. R. Vavricka, and G. A. Kullak-Ublick. 2006. The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G476-G485.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Landrier, J.F.1
Eloranta, J.J.2
Vavricka, S.R.3
Kullak-Ublick, G.A.4
-
241
-
-
35748954385
-
Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter
-
Li, N., Z. Cui, F. Fang, J. Y. Lee, and N. Ballatori. 2007. Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter. Biochem. J. 407: 363-372.
-
(2007)
Biochem. J
, vol.407
, pp. 363-372
-
-
Li, N.1
Cui, Z.2
Fang, F.3
Lee, J.Y.4
Ballatori, N.5
-
242
-
-
37249011815
-
FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption
-
Jung, D., T. Inagaki, R. D. Gerard, P. A. Dawson, S. A. Kliewer, D. J. Mangelsdorf, and A. Moschetta. 2007. FXR agonists and FGF15 reduce fecal bile acid excretion in a mouse model of bile acid malabsorption. J. Lipid Res. 48: 2693-2700.
-
(2007)
J. Lipid Res
, vol.48
, pp. 2693-2700
-
-
Jung, D.1
Inagaki, T.2
Gerard, R.D.3
Dawson, P.A.4
Kliewer, S.A.5
Mangelsdorf, D.J.6
Moschetta, A.7
-
243
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki, T., M. Choi, A. Moschetta, L. Peng, C. L. Cummins, J. G. McDonald, G. Luo, S. A. Jones, B. Goodwin, J. A. Richardson, et al. 2005. Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab. 2: 217-225.
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
Luo, G.7
Jones, S.A.8
Goodwin, B.9
Richardson, J.A.10
-
244
-
-
42449087199
-
Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool
-
Davis, R. A., and A. D. Attie. 2008. Deletion of the ileal basolateral bile acid transporter identifies the cellular sentinels that regulate the bile acid pool. Proc. Natl. Acad. Sci. USA. 105: 4965-4966.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4965-4966
-
-
Davis, R.A.1
Attie, A.D.2
-
245
-
-
37249015421
-
Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine
-
Kim, I., S. H. Ahn, T. Inagaki, M. Choi, S. Ito, G. L. Guo, S. A. Kliewer, and F. J. Gonzalez. 2007. Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine. J. Lipid Res. 48: 2664-2672.
-
(2007)
J. Lipid Res
, vol.48
, pp. 2664-2672
-
-
Kim, I.1
Ahn, S.H.2
Inagaki, T.3
Choi, M.4
Ito, S.5
Guo, G.L.6
Kliewer, S.A.7
Gonzalez, F.J.8
-
246
-
-
38049103287
-
Resolving the mechanism of bile acid negative-feedback regulation, a Journal of Lipid Research tradition
-
Davis, R. A. 2008. Resolving the mechanism of bile acid negative-feedback regulation, a Journal of Lipid Research tradition. J. Lipid Res. 49: 2-3.
-
(2008)
J. Lipid Res
, vol.49
, pp. 2-3
-
-
Davis, R.A.1
-
247
-
-
0141571088
-
Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE -/- mice by SC-435
-
Bhat, B. G., S. R. Rapp, J. A. Beaudry, N. Napawan, D. N. Butteiger, K. A. Hall, C. L. Null, Y. Luo, and B. T. Keller. 2003. Inhibition of ileal bile acid transport and reduced atherosclerosis in apoE -/- mice by SC-435. J. Lipid Res. 44: 1614-1621.
-
(2003)
J. Lipid Res
, vol.44
, pp. 1614-1621
-
-
Bhat, B.G.1
Rapp, S.R.2
Beaudry, J.A.3
Napawan, N.4
Butteiger, D.N.5
Hall, K.A.6
Null, C.L.7
Luo, Y.8
Keller, B.T.9
-
248
-
-
0036692428
-
Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94
-
Root, C., C. D. Smith, S. S. Sundseth, H. M. Pink, J. G. Wilson, and M. C. Lewis. 2002. Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94. J. Lipid Res. 43: 1320-1330.
-
(2002)
J. Lipid Res
, vol.43
, pp. 1320-1330
-
-
Root, C.1
Smith, C.D.2
Sundseth, S.S.3
Pink, H.M.4
Wilson, J.G.5
Lewis, M.C.6
-
249
-
-
0014830893
-
Diminished bile acid pool size in patients with gallstones
-
Vlahcevic, Z. R., C. C. Bell, Jr., I. Buhac, J. T. Farrar, and L. Swell. 1970. Diminished bile acid pool size in patients with gallstones. Gastroenterology. 59: 165-173.
-
(1970)
Gastroenterology
, vol.59
, pp. 165-173
-
-
Vlahcevic, Z.R.1
Bell Jr., C.C.2
Buhac, I.3
Farrar, J.T.4
Swell, L.5
-
250
-
-
53149086301
-
Reduced ileal expression of OSTalpha-OSTbeta in non-obese gallstone disease
-
Renner, O., S. Harsch, A. Strohmeyer, S. Schimmel, and E. F. Stange. 2008. Reduced ileal expression of OSTalpha-OSTbeta in non-obese gallstone disease. J. Lipid Res. 49: 2045-2054.
-
(2008)
J. Lipid Res
, vol.49
, pp. 2045-2054
-
-
Renner, O.1
Harsch, S.2
Strohmeyer, A.3
Schimmel, S.4
Stange, E.F.5
-
251
-
-
30844445030
-
FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine
-
Lee, H., Y. Zhang, F. Y. Lee, S. F. Nelson, F. J. Gonzalez, and P. A. Edwards. 2006. FXR regulates organic solute transporters alpha and beta in the adrenal gland, kidney, and intestine. J. Lipid Res. 47: 201-214.
-
(2006)
J. Lipid Res
, vol.47
, pp. 201-214
-
-
Lee, H.1
Zhang, Y.2
Lee, F.Y.3
Nelson, S.F.4
Gonzalez, F.J.5
Edwards, P.A.6
-
252
-
-
33645839049
-
Coordinated induction of bile acid detoxification and alternative elimination in mice: Role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids
-
Zollner, G., M. Wagner, T. Moustafa, P. Fickert, D. Silbert, J. Gumhold, A. Fuchsbichler, E. Halilbasic, H. Denk, H. U. Marschall, et al. 2006. Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids. Am. J. Physiol. Gastrointest. Liver Physiol. 290: G923-G932.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Zollner, G.1
Wagner, M.2
Moustafa, T.3
Fickert, P.4
Silbert, D.5
Gumhold, J.6
Fuchsbichler, A.7
Halilbasic, E.8
Denk, H.9
Marschall, H.U.10
-
253
-
-
33846049564
-
LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR
-
Okuwaki, M., T. Takada, Y. Iwayanagi, S. Koh, Y. Kariya, H. Fujii, and H. Suzuki. 2007. LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR. Pharm. Res. 24: 390-398.
-
(2007)
Pharm. Res
, vol.24
, pp. 390-398
-
-
Okuwaki, M.1
Takada, T.2
Iwayanagi, Y.3
Koh, S.4
Kariya, Y.5
Fujii, H.6
Suzuki, H.7
-
254
-
-
0015978687
-
Bile salt sulphates in cholestasis
-
Stiehl, A. 1974. Bile salt sulphates in cholestasis. Eur. J. Clin. Invest. 4: 59-63.
-
(1974)
Eur. J. Clin. Invest
, vol.4
, pp. 59-63
-
-
Stiehl, A.1
-
255
-
-
0016480048
-
Sulfation and renal excretion of bile salts in patients with cirrhosis of the liver
-
Stiehl, A., D. L. Earnest, and W. H. Admirant. 1975. Sulfation and renal excretion of bile salts in patients with cirrhosis of the liver. Gastroenterology. 68: 534-544.
-
(1975)
Gastroenterology
, vol.68
, pp. 534-544
-
-
Stiehl, A.1
Earnest, D.L.2
Admirant, W.H.3
-
256
-
-
0019519798
-
Altered bile acid metabolism in primary biliary cirrhosis
-
Raedsch, R., B. H. Lauterburg, and A. F. Hofmann. 1981. Altered bile acid metabolism in primary biliary cirrhosis. Dig. Dis. Sci. 26: 394-401.
-
(1981)
Dig. Dis. Sci
, vol.26
, pp. 394-401
-
-
Raedsch, R.1
Lauterburg, B.H.2
Hofmann, A.F.3
-
257
-
-
0346020356
-
Bile acid content of human serum. I. Serum bile acids in patients with hepatic disease
-
Rudman, D., and F. E. Kendall. 1957. Bile acid content of human serum. I. Serum bile acids in patients with hepatic disease. J. Clin. Invest. 36: 530-537.
-
(1957)
J. Clin. Invest
, vol.36
, pp. 530-537
-
-
Rudman, D.1
Kendall, F.E.2
-
258
-
-
0019425060
-
Sodium-coupled taurocholate transport in the proximal convolution of the rat kidney in vivo and in vitro
-
Wilson, F. A., G. Burckhardt, H. Murer, G. Rumrich, and K. J. Ullrich. 1981. Sodium-coupled taurocholate transport in the proximal convolution of the rat kidney in vivo and in vitro. J. Clin. Invest. 67: 1141-1150.
-
(1981)
J. Clin. Invest
, vol.67
, pp. 1141-1150
-
-
Wilson, F.A.1
Burckhardt, G.2
Murer, H.3
Rumrich, G.4
Ullrich, K.J.5
-
259
-
-
0010670423
-
Renal excretion of bile acids: Taurocholic, glycocholic, and colic acids
-
Weiner, I. M., J. E. Glasser, and L. Lack. 1964. Renal excretion of bile acids: taurocholic, glycocholic, and colic acids. Am. J. Physiol. 207: 964-970.
-
(1964)
Am. J. Physiol
, vol.207
, pp. 964-970
-
-
Weiner, I.M.1
Glasser, J.E.2
Lack, L.3
-
260
-
-
0028323006
-
Specifi c inhibitors of ileal bile acid transport
-
Wess, G., W. Kramer, A. Enhsen, H. Glombik, K. H. Baringhaus, G. Boger, M. Urmann, K. Bock, H. Kleine, G. Neckermann, et al. 1994. Specifi c inhibitors of ileal bile acid transport. J. Med. Chem. 37: 873-875.
-
(1994)
J. Med. Chem
, vol.37
, pp. 873-875
-
-
Wess, G.1
Kramer, W.2
Enhsen, A.3
Glombik, H.4
Baringhaus, K.H.5
Boger, G.6
Urmann, M.7
Bock, K.8
Kleine, H.9
Neckermann, G.10
-
261
-
-
0031842184
-
Inhibition of ileal Na+/bile acid cotransporter by S-8921 reduces serum cholesterol and prevents atherosclerosis in rabbits
-
Higaki, J., S. Hara, N. Takasu, K. Tonda, K. Miyata, T. Shike, K. Nagata, and T. Mizui. 1998. Inhibition of ileal Na+/bile acid cotransporter by S-8921 reduces serum cholesterol and prevents atherosclerosis in rabbits. Arterioscler. Thromb. Vasc. Biol. 18: 1304-1311.
-
(1998)
Arterioscler. Thromb. Vasc. Biol
, vol.18
, pp. 1304-1311
-
-
Higaki, J.1
Hara, S.2
Takasu, N.3
Tonda, K.4
Miyata, K.5
Shike, T.6
Nagata, K.7
Mizui, T.8
-
262
-
-
0034615121
-
A novel class of apical sodium co-dependent bile acid transporter inhibitors: The 2,3-disubstituted-4-phenylquinolines
-
Tollefson, M. B., W. F. Vernier, H. C. Huang, F. P. Chen, E. J. Reinhard, J. Beaudry, B. T. Keller, and D. B. Reitz. 2000. A novel class of apical sodium co-dependent bile acid transporter inhibitors: the 2,3-disubstituted-4-phenylquinolines. Bioorg. Med. Chem. Lett. 10: 277-279.
-
(2000)
Bioorg. Med. Chem. Lett
, vol.10
, pp. 277-279
-
-
Tollefson, M.B.1
Vernier, W.F.2
Huang, H.C.3
Chen, F.P.4
Reinhard, E.J.5
Beaudry, J.6
Keller, B.T.7
Reitz, D.B.8
-
263
-
-
0017580907
-
Evidence for renal control of urinary excretion of bile acids and bile acid sulphates in the cholestatic syndrome
-
Summerfield, J. A., J. Cullen, S. Barnes, and B. H. Billing. 1977. Evidence for renal control of urinary excretion of bile acids and bile acid sulphates in the cholestatic syndrome. Clin. Sci. Mol. Med. 52: 51-65.
-
(1977)
Clin. Sci. Mol. Med
, vol.52
, pp. 51-65
-
-
Summerfield, J.A.1
Cullen, J.2
Barnes, S.3
Billing, B.H.4
-
264
-
-
0019859425
-
Urinary excretion of bile acids in cholestasis: Evidence for renal tubular secretion in man
-
Corbett, C. L., T. C. Bartholomew, B. H. Billing, and J. A. Summerfield. 1981. Urinary excretion of bile acids in cholestasis: evidence for renal tubular secretion in man. Clin. Sci. (Lond.). 61: 773-780.
-
(1981)
Clin. Sci. (Lond.)
, vol.61
, pp. 773-780
-
-
Corbett, C.L.1
Bartholomew, T.C.2
Billing, B.H.3
Summerfield, J.A.4
-
265
-
-
36248935603
-
The use of high performance thin-layer chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage
-
Morgan, W. A., T. Nk, and Y. Ding. 2008. The use of high performance thin-layer chromatography to determine the role of membrane lipid composition in bile salt-induced kidney cell damage. J. Pharmacol. Toxicol. Methods. 57: 70-73.
-
(2008)
J. Pharmacol. Toxicol. Methods
, vol.57
, pp. 70-73
-
-
Morgan, W.A.1
Nk, T.2
Ding, Y.3
-
266
-
-
62149137376
-
Analysis of DNA methylation and histone modification profiles of liver-specific transporters
-
Imai, S., R. Kikuchi, H. Kusuhara, S. Yagi, K. Shiota, and Y. Sugiyama. 2009. Analysis of DNA methylation and histone modification profiles of liver-specific transporters. Mol. Pharmacol. 75: 568-576.
-
(2009)
Mol. Pharmacol
, vol.75
, pp. 568-576
-
-
Imai, S.1
Kikuchi, R.2
Kusuhara, H.3
Yagi, S.4
Shiota, K.5
Sugiyama, Y.6
-
267
-
-
32044467118
-
24-norursodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert, P., M. Wagner, H. U. Marschall, A. Fuchsbichler, G. Zollner, O. Tsybrovskyy, K. Zatloukal, J. Liu, M. P. Waalkes, C. Cover, et al. 2006. 24-norursodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology. 130: 465-481.
-
(2006)
Gastroenterology
, vol.130
, pp. 465-481
-
-
Fickert, P.1
Wagner, M.2
Marschall, H.U.3
Fuchsbichler, A.4
Zollner, G.5
Tsybrovskyy, O.6
Zatloukal, K.7
Liu, J.8
Waalkes, M.P.9
Cover, C.10
|