The Farnesoid X Receptor Controls Gene Expression in a Ligand- and Promoter-selective Fashion

Journal of Biological Chemistry

Volumn 279, Issue 10, 2004, Pages 8856-8861

  Lew, Jane L ^a   Zhao, Annie ^a   Yu, Jinghua ^a   Huang, Li ^a   De Pedro, Nuria ^b   Peláez, Fernando ^b   Wright, Samuel D ^a   Cui, Jisong ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

^b Medical affairs Merck sharp and Dohme ltd   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOCHEMISTRY; CHEMICAL ACTIVATION; CHEMICAL BONDS; CHOLESTEROL; CONFORMATIONS; ENZYME KINETICS; FEEDBACK; HORMONES;

GENE EXPRESSION; GENE TRANSCRIPTION;

GENETIC ENGINEERING;

BILE ACID; CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; CHOLESTEROL 7ALPHA MONOOXYGENASE; CHOLIC ACID; DEOXYCHOLIC ACID; FARNESOID X RECEPTOR; GLUTATHIONE TRANSFERASE; LIGAND; LITHOCHOLIC ACID; LUCIFERASE; URSODEOXYCHOLIC ACID;

ARTICLE; AUTOREGULATION; BILE ACID SYNTHESIS; CHOLESTEROL METABOLISM; ENZYME ACTIVITY; FEEDBACK SYSTEM; GENE CONTROL; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LIGAND BINDING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN CONFORMATION; PROTEIN TARGETING; TARGET CELL; TRANSACTIVATION;

CELL LINE; CHENODEOXYCHOLIC ACID; CHOLATES; DEOXYCHOLIC ACID; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; PROMOTER REGIONS (GENETICS); PROTEIN CONFORMATION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; URSODEOXYCHOLIC ACID;

EID: 1542275425     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M306422200     Document Type: Article

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