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Volumn 277, Issue 35, 2002, Pages 31441-31447

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity

(9) Yu, Jinghua a,b Lo, Jane L a,b Huang, Li a,b Zhao, Annie a,b Metzger, Edward a,b Adams, Alan a,b Meinke, Peter T a,b Wright, Samuel D a,b Cui, Jisong a,b

a Department of Atherosclerosis and Endocrinology ^* (United States)

b MERCK RESEARCH LABORATORIES (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL ORGANS; CELLS; DRUG DOSAGE; HYDROPHOBICITY; RNA;

BILE SALTS;

BIOCHEMISTRY;

3 [2 [2 CHLORO 4 [3 (2,6 DICHLOROPHENYL) 5 ISOPROPYL 4 ISOXAZOLYLMETHOXY]PHENYL]VINYL]BENZOIC ACID; BILE SALT EXPORT PUMP; CARRIER PROTEIN; CHENODEOXYCHOLIC ACID; CYTOCHROME P450; CYTOCHROME P450 7A; DRUG; FARNESOID X RECEPTOR; FARNESOID X RECEPTOR AGONIST; FARNESOID X RECEPTOR ANTAGONIST; LIGAND; LITHOCHOLIC ACID; MESSENGER RNA; RECEPTOR; RECEPTOR BLOCKING AGENT; RECEPTOR STIMULATING AGENT; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IC 50; INTRAHEPATIC CHOLESTASIS; LIVER CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; TRANSACTIVATION;

ATP-BINDING CASSETTE TRANSPORTERS; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA-BINDING PROTEINS; ESCHERICHIA COLI; GENE EXPRESSION REGULATION, NEOPLASTIC; GLUTATHIONE TRANSFERASE; HUMANS; ISOXAZOLES; LITHOCHOLIC ACID; MIXED FUNCTION OXYGENASES; POLYMERASE CHAIN REACTION; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECOMBINANT FUSION PROTEINS; RIFAMPIN; RNA, MESSENGER; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR CELLS, CULTURED;

ANIMALIA;

EID: 0037199946 PISSN: 00219258 EISSN: None Source Type: Journal
DOI: 10.1074/jbc.M200474200 Document Type: Article

Times cited : (165)

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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.