Protein kinase B/Akt mediates cAMP- and cell swelling-stimulated Na +/taurocholate cotransport and Ntcp translocation

Journal of Biological Chemistry

Volumn 277, Issue 32, 2002, Pages 28578-28583

  Webster, Cynthia R L ^a   Srinivasulu, Usha ^a   Ananthanarayanan, Meenakshisundaram ^b   Suchy, Frederick J ^b   Anwer, M Sawkat ^a  

^a TUFTS UNIVERSITY   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ENERGY; BIOCHEMISTRY; CELLS; ENZYME INHIBITION; SODIUM;

CELL SWELLING; CELL TRANSLOCATION; PROTEIN KINASE; TAUROCHOLATE (TC);

ENZYMES;

4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 8 (4 CHLOROPHENYLTHIO) CYCLIC AMP; CYCLIC AMP; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SODIUM ION; TAUROCHOLIC ACID; AKT1 PROTEIN, RAT; CARRIER PROTEIN; CHOLAGOGUE; COTRANSPORTER; ENZYME INHIBITOR; IMIDAZOLE DERIVATIVE; MITOGEN ACTIVATED PROTEIN KINASE; ONCOPROTEIN; ORGANIC ANION TRANSPORTER; PROTEIN SERINE THREONINE KINASE; PYRIDINE DERIVATIVE; SODIUM; SODIUM BILE ACID COTRANSPORTER; SODIUM-BILE ACID COTRANSPORTER;

ARTICLE; CELL LINE; CELL SWELLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INTERMETHOD COMPARISON; LIVER CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; ANIMAL; CELL CULTURE; CYTOLOGY; LIVER; METABOLISM; PROTEIN BINDING; RAT;

ANIMALS; CARRIER PROTEINS; CELLS, CULTURED; CHOLAGOGUES AND CHOLERETICS; CYCLIC AMP; ENZYME INHIBITORS; HEPATOCYTES; IMIDAZOLES; LIVER; MEMBRANE TRANSPORT PROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTEIN BINDING; PROTEIN TRANSPORT; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; PYRIDINES; RATS; SIGNAL TRANSDUCTION; SODIUM; SYMPORTERS; TAUROCHOLIC ACID; TRANSFECTION;

EID: 0037047389     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M201937200     Document Type: Article

References (39)

1. Rameh, L. E., and Cantley, L. C. (1999) J. Biol. Chem. 274, 8347-8350
2. Toker, A. (2000) Mol. Pharmacol. 57, 652-658
3. Downward, J. (1998) Science 279, 673
4. Hatano, E., and Brenner, D. A. (2001) Am. J. Physiol. Gastrointest. Liver Physiol. 281, 1357-1368
5. Hernandez, R., Teruel, T., and Lorenzo, M. (2001) FEBS Lett. 494, 225-231
6. Wang, Q., Somwar, R., Bilan, P. J., Liu, Z., Jin, J., Woodgett, J. R., and Klip, A. (1999) Mol. Cell. Biol. 19, 4008-4018
7. Kohn, A. D., Summers, S. A., Birnbaum, M. J., and Roth, R. A. (1996) J. Biol. Chem. 271, 31372-31378
8. Ueki, K., Yamamoto-Honda, R., Kaburagi, Y., Yamauchi, T., Tobe, K., Burgering, B. M. T., Coffer, P. J., Komuro, I., Akanuma, Y., Yazaki, Y., and Kadowaki, T. (1998) J. Biol. Chem. 273, 5315-5322
9. Foster, L. J., Li, D., Randhawa, V. K., and Klip, A. (2001) J. Biol. Chem. 276, 44212-44221
10. Misra, S., Ujhazy, P., Varticovski, L., and Arias, I. M. (1999) Proc. Natl. Acad. Sci. U. S. A. 96, 5814-5819
11. Misra, S., Ujházy, P., Gatmaitan, Z., Varticovski, L., and Arias, I. M. (1998) J. Biol. Chem. 273, 26638-26644
12. Kurz, A. K., Block, C., Graf, D., Dahl, S. V., Schliess, F., and Haussinger, D. (2000) Biochem. J. 350, 207-213
13. Feranchak, A. P., Roman, R. M., Doctor, R. B., Salter, K. D., Toker, A., and Fitz, J. G. (1999) J. Biol. Chem. 274, 30979-30986
14. Mukhopadhayay, S., Ananthanarayanan, M., Stieger, B., Meier, P. J., Suchy, F. J., and Anwer, M. S. (1998) Hepatology 28, 1629-1636
15. Anwer, M. S. (1998) Curr. Opin. Gastroenterol. 14, 182-190
16. Trauner, M., Meier, P. J., and Boyer, J. L. (1999) J. Hepatol. 31, 165-178
17. Meier, P. J., and Stieger, B. (2000) News Physiol. Sci. 15, 89-93
18. Simon F. R., Fortune, J., Iwahashi, M., Gartung, C., Wolkoff, A., and Sutherland, E. (1996) Am. J. Physiol. 271, G1043-G1052
19. Gartung, C., Schuele, S., Schlosser, S. F., and Boyer, J. L. (1997) Hepatology 25, 284-290
20. Moseley, R. H., Wang, W., Takeda, H., Lown, K., Shick, L., Ananthanarayanan, M., and Suchy, F. J. (1996) Am. J. Physiol. 271, G137-G146
21. Lee, J. M., Stieger, B., Soroka, C. J., Stieger, B., Meier, P. J., and Boyer, J. L. (2000) Gastroenterology 118, 163-172
22. Liu, Y., Suchy, F. J., Silverman, J. A., and Vore, M. (1997) Am. J. Physiol. 272, G46-G53
23. Webster, C. R. L., and Anwer, M. S. (1999) Am. J. Physiol. 277, G1165-G1172
24. Webster, C. R. L., Blanch, C. J., Philips, J., and Anwer, M. S. (2000) J. Biol. Chem. 275, 29754-29760
25. Lali, F. V., Hunt, A. E., Turner, S. J., and Foxwell, B. M. (2000) J. Biol. Chem. 275, 7395-7402
26. Ananthanarayanan, M., NG, O.-C., Boyer, J. L., and Suchy, F. J. (1994) Am. J. Physiol. 267, G637-G643
27. Higuchi, H., Bronk, S. F., Takikawa, Y., Werneburg, N., Takimoto, R., El Deiry, W., and Gores, G. J. (2001) J. Biol. Chem. 276, 38610-38618
28. Burgering, B. M., and Coffer, P. J. (1995) Nature 376, 599-602
29. van Weeren, P. C., de Bruyn, K. M., Vries-Smits, A. M., van Lint, J., and Burgering, B. M. (1998) J. Biol. Chem. 273, 13150-13156
30. Anwer, M. S., Kroker, R., and Hegner, D. (1976) Hoppe-Seyler's Z. Physiol. Chem. 357, 1477-1486
31. Anwer, M. S., and Hegner, D. (1978) Hoppe-Seyler's Z. Physiol. Chem. 359, 181-192
32. Laemmli, U. K. (1970) Nature 227, 680-685
33. Mukhopadhayay, S., Ananthanarayanan, M., Stieger, B., Meier, P. J., Suchy, F. J., and Anwer, M. S. (1997) Am. J. Physiol. 273, G842-G848
34. Lowry, D. H., Rosenberg, N. J., Farr, A. L., and Randall, R. J. (1951) J. Biol. Chem. 193, 265-275
35. Sweeney, G., Somwar, R., Ramlal, T., Volchuk, A., Ueyama, A., and Klip, A. (1999) J. Biol. Chem. 274, 10071-10078
36. Dranoff, J. A., McClure, M., Burgstahler, A. D., Denson, L. A., Crawford, A. R., Crawford, J. M., Karpen, S. J., and Nathanson, M. H. (1999) Hepatology 30, 223-229
37. Hayakawa, T., Bruck, R., Ng, O. C., and Boyer, J. L. (1990) Am. J. Physiol. 259, G727-G735
38. Misra, S., Ujhazy, P., Arias, I. M., and Varticovski, L. (1999) Hepatology 30, 306 (abstr.)
39. Kurz, A. K., Graf, D., Schmitt, M., Dahl, S. V., and Haussinger, D. (2001) Gastroenterology 121, 407-419