Detoxification of lithocholic acid, a toxic bile-acid: Relevance to drug hepatotoxicity

Drug Metabolism Reviews

Volumn 36, Issue 3-4, 2004, Pages 703-722

  Hofmann, Alan F ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Bile acid metabolism; Chenodeoxycholic acid; Dehydroxylation; Sulfation; Sulfotransferase

Indexed keywords

CELL NUCLEUS RECEPTOR; CHENODEOXYCHOLIC ACID; LITHOCHOLIC ACID; SULFOTRANSFERASE; URSODEOXYCHOLIC ACID;

BABOON; BILE ACID METABOLISM; CELL STRAIN CACO 2; CHIMPANZEE; DEHYDROXYLATION; DOSE TIME EFFECT RELATION; DRUG CONJUGATION; DRUG DETOXIFICATION; DRUG RECEPTOR BINDING; DRUG SULFATION; DRUG TRANSPORT; GENE INDUCTION; HUMAN; HYDROXYLATION; INTESTINE CELL; LIVER TOXICITY; MOLECULAR EVOLUTION; NONHUMAN; RABBIT; REVIEW; RHESUS MONKEY; RODENT; SPECIES DIFFERENCE; TOXICOKINETICS;

ANIMALS; BILE ACIDS AND SALTS; HUMANS; LITHOCHOLIC ACID; LIVER;

EID: 7544221726     PISSN: 03602532     EISSN: None     Source Type: Journal    
DOI: 10.1081/DMR-200033475     Document Type: Review

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