Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides

Journal of Hepatology

Volumn 44, Issue 4, 2006, Pages 768-775

  Zelcer, Noam ^a,f   Wetering, Koen Van De ^a   Waart, Rudi De ^b   Scheffer, George L ^c   Marschall, Hanns Ulrich ^d   Wielinga, Peter R ^a   Kuil, Annemieke ^a   Kunne, Cindy ^b   Smith, Alexander ^b   Valk, Martin Van Der ^a   Wijnholds, Jan ^e   Elferink, Ronald Oude ^b   Borst, Piet ^a  

^a NETHERLANDS CANCER INSTITUTE   (Netherlands)

^b ACADEMIC MEDICAL CENTER   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e NETHERLANDS INSTITUTE FOR NEUROSCIENCE   (Netherlands)

^f UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bilirubin; Cholestasis; Enterohepatic circulation; Liver; Multidrug resistance

Indexed keywords

BILE SALT; BILIRUBIN; BILIRUBIN GLUCURONIDE; CHOLIC ACID DERIVATIVE; GLUCURONIDE; HYODEOXYCHOLIC ACID; MULTIDRUG RESISTANCE PROTEIN 3; TAUROCHOLIC ACID;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BILE DUCT LIGATION; BILE FLOW; BILE LEVEL; BILIRUBIN BLOOD LEVEL; BLOOD LEVEL; CHOLESTASIS; CONTROLLED STUDY; EXPLANT; IN VITRO STUDY; IN VIVO STUDY; LIVER INJURY; LIVER PERFUSION; LIVER SINUSOID; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN TRANSPORT; SODIUM EXCRETION; TISSUE DISTRIBUTION; TRANSPORT VESICLE; WILD TYPE;

ANIMALS; BILE ACIDS AND SALTS; BILE DUCTS; BILIRUBIN; BIOLOGICAL TRANSPORT; CHOLIC ACIDS; DEOXYCHOLIC ACID; GLUCURONIDES; ILEUM; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; LIGATION; LIVER; MALE; MICE; MICE, INBRED STRAINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; TAUROCHOLIC ACID;

EID: 33644910207     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2005.07.022     Document Type: Article

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