Down-regulation of Cholesterol 7α-Hydroxylase (CYP7A1) Gene Expression by Bile Acids in Primary Rat Hepatocytes is Mediated by the c-Jun N-terminal Kinase Pathway

Journal of Biological Chemistry

Volumn 276, Issue 19, 2001, Pages 15816-15822

  Gupta, Seema ^a   Stravitz, R Todd ^a   Dent, Paul ^b   Hylemon, Phillip B ^c  

^a VIRGINIA COMMONWEALTH UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^c VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIODIVERSITY; BODY FLUIDS; CHOLESTEROL; ENZYMES; MUTAGENESIS; RNA; TUMORS;

HEPATOCYTES;

GENES;

BILE ACID; CELL PROTEIN; CHOLESTEROL 7ALPHA MONOOXYGENASE; FARNESOID X RECEPTOR; MESSENGER RNA; PROTEIN TYROSINE PHOSPHATASE SHP 1; RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; TAUROCHOLIC ACID; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; LUCIFERASE; MITOGEN ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; TAURINE;

ANIMAL CELL; ARTICLE; CELL CULTURE; FEEDBACK SYSTEM; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; HYDROPHOBICITY; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN INDUCTION; RAT; TRANSCRIPTION REGULATION; ANIMAL; CYTOLOGY; DRUG EFFECT; ENZYMOLOGY; GENETIC TRANSFECTION; GENETICS; HUMAN; KINETICS; LIVER; METABOLISM; MOLECULAR GENETICS; MOUSE; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; REPORTER GENE; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALIA;

ANIMALS; BASE SEQUENCE; BILE ACIDS AND SALTS; CELLS, CULTURED; CHOLESTEROL 7-ALPHA-HYDROXYLASE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; GENES, REPORTER; HEPATOCYTES; HUMANS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; KINETICS; LIVER; LUCIFERASES; MALE; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 8; MITOGEN-ACTIVATED PROTEIN KINASES; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, NUCLEIC ACID; TAURINE; TRANSCRIPTION, GENETIC; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0035844156     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M010878200     Document Type: Article

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