-
3
-
-
50249094665
-
-
Nair, P. P. and Kritchevsky, D. The Bile Acids: Chemistry, Physiology, and Metabolism four Plenum Press, New York
-
Nair, P. P. and Kritchevsky, D. The Bile Acids: Chemistry, Physiology, and Metabolism (four volumes) Plenum Press, New York.
-
-
-
-
4
-
-
0004287549
-
Sterols and Bile Acids
-
Neuberger, A. and Van Deenen, L. L. M, eds, pp, Elsevier Science Publishers, Amsterdam
-
Danielsson, H. and Sjövall, J. (1985) Sterols and Bile Acids. In New Comprehensive Biochemistry (Neuberger, A. and Van Deenen, L. L. M., eds), pp. 447. Elsevier Science Publishers, Amsterdam.
-
(1985)
New Comprehensive Biochemistry
, pp. 447
-
-
Danielsson, H.1
Sjövall, J.2
-
5
-
-
50249175187
-
-
Springer-Verlag, Berlin
-
Joseph, E. and Radt, F. (1946) Encyclopedia of Organic Chemistry, volume 145, pp. 3092. Springer-Verlag, Berlin.
-
(1946)
Encyclopedia of Organic Chemistry
, vol.145
, pp. 3092
-
-
Joseph, E.1
Radt, F.2
-
7
-
-
1542723711
-
-
Kakiyama, G., Iida, T., Yoshimoto, A., Goto, T., Mano, N., Goto, J., Nambara, T., Hagey, L. R. and Hofmann, A. F. (2004). Chemical synthesis of (22E)-3 alpha,6 beta,7 beta-trihydroxy-5 beta-chol-22-en-24-oic acid and its taurine and glycine conjugates: a major bile acid in the rat. J. Lipid Res. 45, 567-573.
-
Kakiyama, G., Iida, T., Yoshimoto, A., Goto, T., Mano, N., Goto, J., Nambara, T., Hagey, L. R. and Hofmann, A. F. (2004). Chemical synthesis of (22E)-3 alpha,6 beta,7 beta-trihydroxy-5 beta-chol-22-en-24-oic acid and its taurine and glycine conjugates: a major bile acid in the rat. J. Lipid Res. 45, 567-573.
-
-
-
-
8
-
-
84889773353
-
-
Keppler, D, Beuers, U, Leuschner, U, Stiehl, A, Trauner, M. and Paumgartner, G, eds, Springer, Dordrecht
-
Keppler, D., Beuers, U., Leuschner, U., Stiehl, A., Trauner, M. and Paumgartner, G., eds. (2007) Bile Acids: Biological Actions and Clinical Relevance, pp. 265. Springer, Dordrecht.
-
(2007)
Bile Acids: Biological Actions and Clinical Relevance
, pp. 265
-
-
-
9
-
-
0026606455
-
A proposed nomenclature for bile acids
-
Hofmann, A. F., Sjövall, J., Kurz, G., Radominska A., Schteingart, C. D., Tint, G. S., Vlahcevic, Z. R. and Setchell, K. D. (1992). A proposed nomenclature for bile acids. J. Lipid Res. 33, 599-604.
-
(1992)
J. Lipid Res
, vol.33
, pp. 599-604
-
-
Hofmann, A.F.1
Sjövall, J.2
Kurz, G.3
Radominska, A.4
Schteingart, C.D.5
Tint, G.S.6
Vlahcevic, Z.R.7
Setchell, K.D.8
-
10
-
-
0020626591
-
The influence of bile salt structure on self-association in aqueous solutions
-
Roda, A., Hofmann, A. F. and Mysels, K. J. (1983). The influence of bile salt structure on self-association in aqueous solutions. J. Biol. Chem. 258, 6362-6370.
-
(1983)
J. Biol. Chem
, vol.258
, pp. 6362-6370
-
-
Roda, A.1
Hofmann, A.F.2
Mysels, K.J.3
-
11
-
-
0002354055
-
Physical-chemical properties of bile acids and their salts
-
Danielsson, H. and Sjövall, J, eds, Elsevier, Amsterdam
-
Carey, M. C. (1985) Physical-chemical properties of bile acids and their salts. In Sterols and Bile Acids (Danielsson, H. and Sjövall, J., eds). Elsevier, Amsterdam.
-
(1985)
Sterols and Bile Acids
-
-
Carey, M.C.1
-
12
-
-
0141459452
-
Physicochemical and physiological properties of 5alpha-cyprinol sulfate, the toxic bile salt of cyprinid fish
-
Goto, T., Holzinger, F., Hagey, L. R., Cerrè, C., Ton-Nu, H-T., Schteingart, C. D., Steinbach, J. H., Shneider, B. L., and Hofmann, A. F. (2003). Physicochemical and physiological properties of 5alpha-cyprinol sulfate, the toxic bile salt of cyprinid fish. J. Lipid Res. 44, 1643-1451.
-
(2003)
J. Lipid Res
, vol.44
, pp. 1643-1451
-
-
Goto, T.1
Holzinger, F.2
Hagey, L.R.3
Cerrè, C.4
Ton-Nu, H.-T.5
Schteingart, C.D.6
Steinbach, J.H.7
Shneider, B.L.8
Hofmann, A.F.9
-
14
-
-
33947157847
-
The structure of conjugated bile salt-fatty acid monoglyceride mixed colloids: Studies by small-angle neutron scattering
-
Hjelm, R. P., Schteingart, C. D., Hofmann, A. F. and Thiyagarajan, P. (2000). The structure of conjugated bile salt-fatty acid monoglyceride mixed colloids: studies by small-angle neutron scattering. J. Phys. Chem. 523, 299-307.
-
(2000)
J. Phys. Chem
, vol.523
, pp. 299-307
-
-
Hjelm, R.P.1
Schteingart, C.D.2
Hofmann, A.F.3
Thiyagarajan, P.4
-
15
-
-
0023307976
-
Bile salts as biological surfactants
-
Hofmann, A. F. and Mysels, K. J. (1988). Bile salts as biological surfactants. Colloids and Surfaces 39, 145-173.
-
(1988)
Colloids and Surfaces
, vol.39
, pp. 145-173
-
-
Hofmann, A.F.1
Mysels, K.J.2
-
16
-
-
25444442926
-
A phylogenetic survey of biliary lipids in vertebrates
-
Moschetta, A., Xu, F., Hagey, L. R., van Berge-Henegouwen, G. P., van Erpecum, K. J., Brouwers, J. F., Cohen, J. C., Bierman, M., Hobbs, H. H., Steinbach, J. H. and Hofmann, A. F. (2005). A phylogenetic survey of biliary lipids in vertebrates. J. Lipid Res. 46, 2221-2232.
-
(2005)
J. Lipid Res
, vol.46
, pp. 2221-2232
-
-
Moschetta, A.1
Xu, F.2
Hagey, L.R.3
van Berge-Henegouwen, G.P.4
van Erpecum, K.J.5
Brouwers, J.F.6
Cohen, J.C.7
Bierman, M.8
Hobbs, H.H.9
Steinbach, J.H.10
Hofmann, A.F.11
-
17
-
-
33846708192
-
Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein)
-
Oude Elferink, R. P. and Paulusma, C. C. (2007). Function and pathophysiological importance of ABCB4 (MDR3 P-glycoprotein). Pflugers Arch. 453, 601-610.
-
(2007)
Pflugers Arch
, vol.453
, pp. 601-610
-
-
Oude Elferink, R.P.1
Paulusma, C.C.2
-
18
-
-
32044467118
-
24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice
-
Fickert, P., Wagner, M., Marschall, H. U., Fuchsbichler, A., Zollner, G., Tsybrovskyy, O., Zatloukal, K., Liu, J., Waalkes, M. P., Cover, C., Denk, H., Hofmann, A. F., Jaeschke, H., and Trauner, M. (2006). 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology 130, 465-481.
-
(2006)
Gastroenterology
, vol.130
, pp. 465-481
-
-
Fickert, P.1
Wagner, M.2
Marschall, H.U.3
Fuchsbichler, A.4
Zollner, G.5
Tsybrovskyy, O.6
Zatloukal, K.7
Liu, J.8
Waalkes, M.P.9
Cover, C.10
Denk, H.11
Hofmann, A.F.12
Jaeschke, H.13
Trauner, M.14
-
19
-
-
0024318186
-
Quantitative estimation of the hydrophilic- hydrophobic balance of mixed bile salt solutions
-
Heuman, D. M. (1989). Quantitative estimation of the hydrophilic- hydrophobic balance of mixed bile salt solutions. J. Lipid Res. 30, 719-730.
-
(1989)
J. Lipid Res
, vol.30
, pp. 719-730
-
-
Heuman, D.M.1
-
20
-
-
0021739393
-
Physicochemical properties of bile acids and their relationship to biological properties: An overview of the problem
-
Hofmann, A. F. and Roda, A. (1984). Physicochemical properties of bile acids and their relationship to biological properties: an overview of the problem. J. Lipid Res. 25, 1477-1489.
-
(1984)
J. Lipid Res
, vol.25
, pp. 1477-1489
-
-
Hofmann, A.F.1
Roda, A.2
-
21
-
-
0002661606
-
Bile Acids
-
In The, Third Edition. Arias, I. M, Boyer, J. L, Fausto, N, Jakoby, W. B, Schacter, D. A. and Shafritz, D. A, eds, pp, Raven Press Limited, New York
-
Hofmann, A. F. (1994) Bile Acids. In The Liver: Biology and Pathobiology. Third Edition. Arias, I. M., Boyer, J. L., Fausto, N., Jakoby, W. B., Schacter, D. A. and Shafritz, D. A., (eds), pp. 677-718. Raven Press Limited, New York.
-
(1994)
Liver: Biology and Pathobiology
, pp. 677-718
-
-
Hofmann, A.F.1
-
22
-
-
0037790917
-
The enzymes, regulation, and genetics of bile acid synthesis
-
Russell, D. W. (2003). The enzymes, regulation, and genetics of bile acid synthesis. Annu. Rev. Biochem. 72, 137-174.
-
(2003)
Annu. Rev. Biochem
, vol.72
, pp. 137-174
-
-
Russell, D.W.1
-
23
-
-
33947617210
-
Enzymes in the conversion of cholesterol into bile acids
-
Norlin, M. and Wikvall, K. (2007). Enzymes in the conversion of cholesterol into bile acids. Current Molecular Medicine 7, 199-218.
-
(2007)
Current Molecular Medicine
, vol.7
, pp. 199-218
-
-
Norlin, M.1
Wikvall, K.2
-
24
-
-
34548118641
-
Inborn errors of bile acid metabolism
-
Heubi, J. E., Setchell, K. D. and Bove, K. E. (2007). Inborn errors of bile acid metabolism. Semin. Liver Dis. 27, 282-294.
-
(2007)
Semin. Liver Dis
, vol.27
, pp. 282-294
-
-
Heubi, J.E.1
Setchell, K.D.2
Bove, K.E.3
-
25
-
-
0023801559
-
Defective bile acid amidation: Predicted features of a new inborn error of metabolism
-
Hofmann, A. F. and Strandvik, B. (1988). Defective bile acid amidation: predicted features of a new inborn error of metabolism. Lancet 2, 311-313.
-
(1988)
Lancet
, vol.2
, pp. 311-313
-
-
Hofmann, A.F.1
Strandvik, B.2
-
26
-
-
33144465413
-
Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice
-
Fickert, P.. Fuchsbichler, A., Marschall, H. U., Wagner, M., Zollner, G., Krause, R., Zatloukal, K., Jaeschke, H., Denk, H. and Trauner, M. (2006). Lithocholic acid feeding induces segmental bile duct obstruction and destructive cholangitis in mice. Am. J. Pathol. 168, 410-422.
-
(2006)
Am. J. Pathol
, vol.168
, pp. 410-422
-
-
Fickert, P.1
Fuchsbichler, A.2
Marschall, H.U.3
Wagner, M.4
Zollner, G.5
Krause, R.6
Zatloukal, K.7
Jaeschke, H.8
Denk, H.9
Trauner, M.10
-
27
-
-
50249112206
-
-
Hofmann, A. F. Enterohepatic circulation of bile acids. (1989) In Handbook of Physiology. Section on the Gastrointestinal System (Schultz, S., ed), pp. 567-596. American Physiological Society, Bethesda.
-
Hofmann, A. F. Enterohepatic circulation of bile acids. (1989) In Handbook of Physiology. Section on the Gastrointestinal System (Schultz, S., ed), pp. 567-596. American Physiological Society, Bethesda.
-
-
-
-
28
-
-
50249149668
-
The enterohepatic circulation of bile acids in mammals: Form and functions
-
in press
-
Hofmann, A. F. (2008). The enterohepatic circulation of bile acids in mammals: form and functions. Frontiers in Bioscience, (in press).
-
(2008)
Frontiers in Bioscience
-
-
Hofmann, A.F.1
-
29
-
-
33846658726
-
The bile salt export pump
-
Stieger, B., Meier, Y. and Meier, P. J. (2006). The bile salt export pump. Pflugers Arch. 453, 611-620.
-
(2006)
Pflugers Arch
, vol.453
, pp. 611-620
-
-
Stieger, B.1
Meier, Y.2
Meier, P.J.3
-
31
-
-
0037379362
-
Bile salt transporters: Molecular characterization, function, and regulation
-
Trauner, M. and Boyer, J. L. (2003). Bile salt transporters: molecular characterization, function, and regulation. Physiol. Rev. 83, 633-671.
-
(2003)
Physiol. Rev
, vol.83
, pp. 633-671
-
-
Trauner, M.1
Boyer, J.L.2
-
32
-
-
0346100571
-
Enterohepatic bile salt transporters in normal physiology and liver disease
-
Kullak-Ublick, G. A., Stieger, B. and Meier, P. J. (2004). Enterohepatic bile salt transporters in normal physiology and liver disease. Gastroenterology 126, 322-342.
-
(2004)
Gastroenterology
, vol.126
, pp. 322-342
-
-
Kullak-Ublick, G.A.1
Stieger, B.2
Meier, P.J.3
-
33
-
-
29644437682
-
Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine
-
Nakahara, M., Furuya, N., Takagaki, K., Sugaya, T., Hirota, K., Fukamizu, A., Kanda, T., Fujii, H. and Sato, R. (2005). Ileal bile acid-binding protein, functionally associated with the farnesoid X receptor or the ileal bile acid transporter, regulates bile acid activity in the small intestine. J. Biol. Chem. 280, 42283-42289.
-
(2005)
J. Biol. Chem
, vol.280
, pp. 42283-42289
-
-
Nakahara, M.1
Furuya, N.2
Takagaki, K.3
Sugaya, T.4
Hirota, K.5
Fukamizu, A.6
Kanda, T.7
Fujii, H.8
Sato, R.9
-
34
-
-
0029920858
-
Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig
-
Amelsberg, A., Schteingart, C. D., Ton-Nu, H. T. and Hofmann, A. F. (1996). Carrier-mediated jejunal absorption of conjugated bile acids in the guinea pig. Gastroenterology 110, 1098-1106.
-
(1996)
Gastroenterology
, vol.110
, pp. 1098-1106
-
-
Amelsberg, A.1
Schteingart, C.D.2
Ton-Nu, H.T.3
Hofmann, A.F.4
-
35
-
-
33749186777
-
Alterations in intestinal permeability
-
Arrieta, M. C., Bistritz, L. and Meddings, J. B. (2006). Alterations in intestinal permeability. Gut 55, 1512-1520.
-
(2006)
Gut
, vol.55
, pp. 1512-1520
-
-
Arrieta, M.C.1
Bistritz, L.2
Meddings, J.B.3
-
36
-
-
33645825217
-
Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione
-
Rius, M., Hummel-Eisenbeiss, J., Hofmann, A. F. and Keppler, D. (2006). Substrate specificity of human ABCC4 (MRP4)-mediated cotransport of bile acids and reduced glutathione. Am. J. Physiol. Gastrointest. Liver Physiol. 290, G640-649.
-
(2006)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.290
-
-
Rius, M.1
Hummel-Eisenbeiss, J.2
Hofmann, A.F.3
Keppler, D.4
-
37
-
-
33645994508
-
-
Doege, H., Baillie, R. A. Ortegon, A. M., Tsang, B., Wu, Q., Punreddy, S., Hirsch, D., Watson, N., Gimeno, R. E. and A. Stahl. et al. (2006). Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology 130, 1245-1258.
-
Doege, H., Baillie, R. A. Ortegon, A. M., Tsang, B., Wu, Q., Punreddy, S., Hirsch, D., Watson, N., Gimeno, R. E. and A. Stahl. et al. (2006). Targeted deletion of FATP5 reveals multiple functions in liver metabolism: alterations in hepatic lipid homeostasis. Gastroenterology 130, 1245-1258.
-
-
-
-
38
-
-
33644695809
-
Uptake of ursodeoxycholate and its conjugates by human hepatocytes: Role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8)
-
Maeda, K., Kambara, M., Tian, Y., Hofmann, A. F. and Sugiyama, Y. (2006). Uptake of ursodeoxycholate and its conjugates by human hepatocytes: role of Na(+)-taurocholate cotransporting polypeptide (NTCP), organic anion transporting polypeptide (OATP) 1B1 (OATP-C), and oatp1B3 (OATP8). Mol. Pharm. 3, 70-77.
-
(2006)
Mol. Pharm
, vol.3
, pp. 70-77
-
-
Maeda, K.1
Kambara, M.2
Tian, Y.3
Hofmann, A.F.4
Sugiyama, Y.5
-
39
-
-
0028363314
-
Effects of side chain length on ionization behavior and transbilayer transport of unconjugated dihydroxy bile acids: A comparison of norchenodeoxycholic acid and chenodeoxycholic acid
-
Ko, J., Hamilton, J. A., Ton-Nu, H. T., Schteingart, C. D., Hofmann, A. F. and Small, D. M. (1994). Effects of side chain length on ionization behavior and transbilayer transport of unconjugated dihydroxy bile acids: a comparison of norchenodeoxycholic acid and chenodeoxycholic acid. J. Lipid Res. 35, 883-892.
-
(1994)
J. Lipid Res
, vol.35
, pp. 883-892
-
-
Ko, J.1
Hamilton, J.A.2
Ton-Nu, H.T.3
Schteingart, C.D.4
Hofmann, A.F.5
Small, D.M.6
-
40
-
-
33847741406
-
Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: Implications for intracellular bile salt transport
-
Pellicoro, A., van den Heuvel, F. A., Geuken, M., Moshage, H., Jansen, P. L. and Faber, K. N. (2007). Human and rat bile acid-CoA:amino acid N-acyltransferase are liver-specific peroxisomal enzymes: implications for intracellular bile salt transport. Hepatology 45, 340-348.
-
(2007)
Hepatology
, vol.45
, pp. 340-348
-
-
Pellicoro, A.1
van den Heuvel, F.A.2
Geuken, M.3
Moshage, H.4
Jansen, P.L.5
Faber, K.N.6
-
41
-
-
0019294767
-
Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: Possible role of bicarbonate transport
-
Dumont, M., Erlinger, S. and Uchman, S. (1980). Hypercholeresis induced by ursodeoxycholic acid and 7-ketolithocholic acid in the rat: possible role of bicarbonate transport. Gastroenterology 79, 82-89.
-
(1980)
Gastroenterology
, vol.79
, pp. 82-89
-
-
Dumont, M.1
Erlinger, S.2
Uchman, S.3
-
42
-
-
0022650127
-
Effect of side-chain shortening on the physiologic properties of bile acids: Hepatic transport and effect on biliary secretion of 23-norursodeoxycholate in rodents
-
Yoon, Y. B., Hagey, L. R., Hofmann, A. F., Gurantz, D., Michelotti, E. L. and Steinbach, J. H. (1986). Effect of side-chain shortening on the physiologic properties of bile acids: hepatic transport and effect on biliary secretion of 23-norursodeoxycholate in rodents. Gastroenterology 90, 837-852.
-
(1986)
Gastroenterology
, vol.90
, pp. 837-852
-
-
Yoon, Y.B.1
Hagey, L.R.2
Hofmann, A.F.3
Gurantz, D.4
Michelotti, E.L.5
Steinbach, J.H.6
-
43
-
-
0030806732
-
24)
-
24). Hepatology 26, 374-385.
-
(1997)
Hepatology
, vol.26
, pp. 374-385
-
-
Yeh, H.-Z.1
Hagey, C.D.2
Ton-Nu, L.R.3
H-T4
Bolder, U.5
Gavrilkina, M.A.6
Steinbach, J.H.7
Hofmann, A.F.8
-
44
-
-
33244467651
-
Bile salt biotransformations by human intestinal bacteria
-
Ridlon, J. M., Kang, D. J. and Hylemon, P. B. (2006). Bile salt biotransformations by human intestinal bacteria. J. Lipid Res. 47, 241-259.
-
(2006)
J. Lipid Res
, vol.47
, pp. 241-259
-
-
Ridlon, J.M.1
Kang, D.J.2
Hylemon, P.B.3
-
45
-
-
37249088332
-
Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15α-hydroxylithocholic acid
-
Kakiyama, G., Tamegai, H., Iida, T., Mitamura, K., Ikegawa, S., Goto, T., Mano, N., Goto, J., Holz, P., Hagey, L. R. and Hofmann, A. F. (2007). Isolation and chemical synthesis of a major, novel biliary bile acid in the common wombat (Vombatus ursinus): 15α-hydroxylithocholic acid. J. Lipid Res. 48, 2682-2692.
-
(2007)
J. Lipid Res
, vol.48
, pp. 2682-2692
-
-
Kakiyama, G.1
Tamegai, H.2
Iida, T.3
Mitamura, K.4
Ikegawa, S.5
Goto, T.6
Mano, N.7
Goto, J.8
Holz, P.9
Hagey, L.R.10
Hofmann, A.F.11
-
46
-
-
0034985734
-
Isoursodeoxycholic acid: Metabolism and therapeutic effects in primary biliary cirrhosis
-
Marschall, H. U., Broome, U., Einarsson, C., Alvelius, G., Thomas, H. G. and Matern, S. (2001). Isoursodeoxycholic acid: metabolism and therapeutic effects in primary biliary cirrhosis. J. Lipid Res. 42, 735-742.
-
(2001)
J. Lipid Res
, vol.42
, pp. 735-742
-
-
Marschall, H.U.1
Broome, U.2
Einarsson, C.3
Alvelius, G.4
Thomas, H.G.5
Matern, S.6
-
47
-
-
0016686524
-
Plasma disappearance of radioactivity after intravenous injection of labeled bile acids in man
-
Cowen, A. E., Korman, M. G., Hofmann, A. F. and Thomas, P. J. (1975). Plasma disappearance of radioactivity after intravenous injection of labeled bile acids in man. Gastroenterology 68, 1567-1573.
-
(1975)
Gastroenterology
, vol.68
, pp. 1567-1573
-
-
Cowen, A.E.1
Korman, M.G.2
Hofmann, A.F.3
Thomas, P.J.4
-
48
-
-
0020679384
-
Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man
-
Hofmann, A. F., Molino, G., Milanese, M., and Belforte, G. (1983). Description and simulation of a physiological pharmacokinetic model for the metabolism and enterohepatic circulation of bile acids in man. Cholic acid in healthy man. J. Clin. Invest 71, 1003-1022.
-
(1983)
J. Clin. Invest
, vol.71
, pp. 1003-1022
-
-
Hofmann, A.F.1
Molino, G.2
Milanese, M.3
Belforte, G.4
-
49
-
-
0022980853
-
Simulation of the metabolism and enterohepatic circulation of endogenous chenodeoxycholic acid in man using a physiological pharmacokinetic model
-
Molino, G., Hofmann, A. F., Cravetto, C., Belforte, G. and Bona, B. (1986). Simulation of the metabolism and enterohepatic circulation of endogenous chenodeoxycholic acid in man using a physiological pharmacokinetic model. Europ. J. Clin. Invest. 16, 397-414.
-
(1986)
Europ. J. Clin. Invest
, vol.16
, pp. 397-414
-
-
Molino, G.1
Hofmann, A.F.2
Cravetto, C.3
Belforte, G.4
Bona, B.5
-
50
-
-
0023280880
-
Simulation of the metabolism and enterohepatic circulation of endogenous deoxycholic acid in man using a physiological pharmacokinetic model for bile acid metabolism
-
Hofmann A. F., Cravetto, C., Molino, G., Belforte, G. and Bona B. (1987). Simulation of the metabolism and enterohepatic circulation of endogenous deoxycholic acid in man using a physiological pharmacokinetic model for bile acid metabolism. Gastroenterology 93, 693-709.
-
(1987)
Gastroenterology
, vol.93
, pp. 693-709
-
-
Hofmann, A.F.1
Cravetto, C.2
Molino, G.3
Belforte, G.4
Bona, B.5
-
51
-
-
1242269851
-
Regulation of bile acid synthesis: Pathways, nuclear receptors, and mechanisms
-
Chiang, J. Y. (2004). Regulation of bile acid synthesis: pathways, nuclear receptors, and mechanisms. J. Hepatol. 40, 539-551.
-
(2004)
J. Hepatol
, vol.40
, pp. 539-551
-
-
Chiang, J.Y.1
-
52
-
-
27844546989
-
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
-
Inagaki, T., Choi, M., Moschetta, A., Peng, L., Cummins, C. L., McDonald, J. G., Luo, G., Jones, S. A., Goodwin, B., Richardson, J. A., Gerard, R. D., Repa, J. J., Mangelsdorf, D. J. and Kliewer, S. A. (2005). Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis. Cell Metab. 2, 217-225.
-
(2005)
Cell Metab
, vol.2
, pp. 217-225
-
-
Inagaki, T.1
Choi, M.2
Moschetta, A.3
Peng, L.4
Cummins, C.L.5
McDonald, J.G.6
Luo, G.7
Jones, S.A.8
Goodwin, B.9
Richardson, J.A.10
Gerard, R.D.11
Repa, J.J.12
Mangelsdorf, D.J.13
Kliewer, S.A.14
-
53
-
-
34848869695
-
Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
-
Kurosu, H., Mihwa, C., Ogawa, Y., Dickson, A. S., Goetz, R., Eliseenkova, A. V., Mohammadi, M., Rosenblatt, K. P., Kliewer, S. A. and Kuro-o, M. (2007). Tissue-specific expression of betaKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21. J. Biol. Chem. 282, 26687-26695.
-
(2007)
J. Biol. Chem
, vol.282
, pp. 26687-26695
-
-
Kurosu, H.1
Mihwa, C.2
Ogawa, Y.3
Dickson, A.S.4
Goetz, R.5
Eliseenkova, A.V.6
Mohammadi, M.7
Rosenblatt, K.P.8
Kliewer, S.A.9
Kuro-o, M.10
-
54
-
-
33745529832
-
Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells
-
Li, T., Jahan, A. and Chiang, J. Y. (2006). Bile acids and cytokines inhibit the human cholesterol 7 alpha-hydroxylase gene via the JNK/c-jun pathway in human liver cells. Hepatology 43, 1202-1210.
-
(2006)
Hepatology
, vol.43
, pp. 1202-1210
-
-
Li, T.1
Jahan, A.2
Chiang, J.Y.3
-
55
-
-
33644797843
-
Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: Discordant regulation of bile acid synthesis and gluconeogenesis
-
Song, K. H. and Chiang, J. Y. (2006). Glucagon and cAMP inhibit cholesterol 7alpha-hydroxylase (CYP7A1) gene expression in human hepatocytes: discordant regulation of bile acid synthesis and gluconeogenesis. Hepatology 43, 117-125.
-
(2006)
Hepatology
, vol.43
, pp. 117-125
-
-
Song, K.H.1
Chiang, J.Y.2
-
56
-
-
0016803477
-
Effect of primary bile acid ingestion on bile acid metabolismand biliary lipid secretion in gallstone patients
-
LaRusso, N. F., Hoffman, N. E., Hofmann, A. F., Northfield, T. C. and Thistle, J. L. (1975). Effect of primary bile acid ingestion on bile acid metabolismand biliary lipid secretion in gallstone patients. Gastroenterology 69, 1301-1314.
-
(1975)
Gastroenterology
, vol.69
, pp. 1301-1314
-
-
LaRusso, N.F.1
Hoffman, N.E.2
Hofmann, A.F.3
Northfield, T.C.4
Thistle, J.L.5
-
57
-
-
0015338557
-
Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride
-
Hofmann, A. F. and Poley, J. R. (1972). Role of bile acid malabsorption in pathogenesis of diarrhea and steatorrhea in patients with ileal resection. I. Response to cholestyramine or replacement of dietary long chain triglyceride by medium chain triglyceride. Gastroenterology 62, 918-934.
-
(1972)
Gastroenterology
, vol.62
, pp. 918-934
-
-
Hofmann, A.F.1
Poley, J.R.2
-
58
-
-
0141818009
-
Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice
-
Dawson, P. A., Haywood, J., Craddock, A. L., Wilson, M., Tietjen, M., Kluckman, K., Maeda, N. and Parks, J. S. (2003). Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice. J. Biol. Chem. 278, 33920-33927.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33920-33927
-
-
Dawson, P.A.1
Haywood, J.2
Craddock, A.L.3
Wilson, M.4
Tietjen, M.5
Kluckman, K.6
Maeda, N.7
Parks, J.S.8
-
59
-
-
50249099871
-
The basolateral transporter OSTalpha-OSTbeta is essential for intestinal bile acid absorption and homeostasis
-
Rao, A., Haywood, J., Craddock, A. L., Belinsky, M. G., Kruh, G. D. and Dawson, P. A. (2007). The basolateral transporter OSTalpha-OSTbeta is essential for intestinal bile acid absorption and homeostasis Hepatology 46, 271A.
-
(2007)
Hepatology
, vol.46
-
-
Rao, A.1
Haywood, J.2
Craddock, A.L.3
Belinsky, M.G.4
Kruh, G.D.5
Dawson, P.A.6
-
60
-
-
0028901070
-
Heterogeneous expression of cholesterol 7 alphahyroxylase and sterol 27-hydroxylase genes in the rat liver lobule
-
Twisk, J., Hoekman, M. F., Mager, W. H., Moorman, A. F., de Boer, P. A., Scheja, L., Princen, H. M. and Gebhardt, R. (1995). Heterogeneous expression of cholesterol 7 alphahyroxylase and sterol 27-hydroxylase genes in the rat liver lobule. J. Clin. Invest. 95, 1235-1243
-
(1995)
J. Clin. Invest
, vol.95
, pp. 1235-1243
-
-
Twisk, J.1
Hoekman, M.F.2
Mager, W.H.3
Moorman, A.F.4
de Boer, P.A.5
Scheja, L.6
Princen, H.M.7
Gebhardt, R.8
-
61
-
-
10844287785
-
FXR-activating ligands inhibit rabbit ASBTexpression via FXR-SHP-FTF cascade
-
Li, H., Chen, F., Shang, Q., Shneider, B. L., Chiang, J. Y. L., Forman, B. M., Ananthanarayanan, M., Tint, G. S., Salen, G. and Xu, G. (2005). FXR-activating ligands inhibit rabbit ASBTexpression via FXR-SHP-FTF cascade. Am. J. Physiol. Gastrointest. Liver Physiol. 288, G60-66.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.288
-
-
Li, H.1
Chen, F.2
Shang, Q.3
Shneider, B.L.4
Chiang, J.Y.L.5
Forman, B.M.6
Ananthanarayanan, M.7
Tint, G.S.8
Salen, G.9
Xu, G.10
-
62
-
-
0029869759
-
Adaptive response of the enterohepatic circulation of bile acids to extrahepatic cholestasis
-
Dumaswala, R., Berkowitz, D. and Heubi, J. E. (1996). Adaptive response of the enterohepatic circulation of bile acids to extrahepatic cholestasis. Hepatology 23, 623-629.
-
(1996)
Hepatology
, vol.23
, pp. 623-629
-
-
Dumaswala, R.1
Berkowitz, D.2
Heubi, J.E.3
-
63
-
-
35148824953
-
Decreased bile acid synthesis with total parenteral nutrition
-
Dawes, L. G., Laut, H. C. and Woodruff, M. (2007). Decreased bile acid synthesis with total parenteral nutrition. Am. J. Surg. 194, 623-627.
-
(2007)
Am. J. Surg
, vol.194
, pp. 623-627
-
-
Dawes, L.G.1
Laut, H.C.2
Woodruff, M.3
-
64
-
-
0016168020
-
Measurement of bile acid kinetics by isotope dilution in man
-
Hofmann, A. F. and Hoffman, N. E. (1974). Measurement of bile acid kinetics by isotope dilution in man. Gastroenterology 67, 314-323.
-
(1974)
Gastroenterology
, vol.67
, pp. 314-323
-
-
Hofmann, A.F.1
Hoffman, N.E.2
-
65
-
-
0035204295
-
Measurement of parameters of cholic acid kinetics in plasma using amicroscale stable isotope dilution technique: Application to rodents and humans
-
Hulzebos, C. V. , Renfurm, L., Bandsma, R. H., Verkade, H. J., Boer, T., Boverhof, R., Tanaka, H., Mierau, I., Sauer, P. J., Kuipers, F., and Stellaard, F. (2001). Measurement of parameters of cholic acid kinetics in plasma using amicroscale stable isotope dilution technique: application to rodents and humans. J. Lipid Res. 42, 1923-1929.
-
(2001)
J. Lipid Res
, vol.42
, pp. 1923-1929
-
-
Hulzebos, C.V.1
Renfurm, L.2
Bandsma, R.H.3
Verkade, H.J.4
Boer, T.5
Boverhof, R.6
Tanaka, H.7
Mierau, I.8
Sauer, P.J.9
Kuipers, F.10
Stellaard, F.11
-
66
-
-
0026032696
-
A simple method for the determination of lipid composition of human bile
-
Muraca, M., Vilei, M. T., Miconi, L., Petrin, P., Antoniutti, M. and Pedrazzoli, S. (1991). A simple method for the determination of lipid composition of human bile. J. Lipid Res. 32, 371-374.
-
(1991)
J. Lipid Res
, vol.32
, pp. 371-374
-
-
Muraca, M.1
Vilei, M.T.2
Miconi, L.3
Petrin, P.4
Antoniutti, M.5
Pedrazzoli, S.6
-
67
-
-
33947383769
-
The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells
-
Keitel, V., Reinehr, R., Gatsios, P., Rupprecht, C., Gorg, B., Selbach, O., Haussinger, D. and Kubitz, R. (2007). The G-protein coupled bile salt receptor TGR5 is expressed in liver sinusoidal endothelial cells. Hepatology 45, 695-704.
-
(2007)
Hepatology
, vol.45
, pp. 695-704
-
-
Keitel, V.1
Reinehr, R.2
Gatsios, P.3
Rupprecht, C.4
Gorg, B.5
Selbach, O.6
Haussinger, D.7
Kubitz, R.8
-
68
-
-
0030778079
-
Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy
-
Crawford, A. R., Smith, A. J., Hatch, V. C., Oude Elferink, R. P., Borst, P. and Crawford, J. M. (1997). Hepatic secretion of phospholipid vesicles in the mouse critically depends on mdr2 or MDR3 P-glycoprotein expression. Visualization by electron microscopy. J. Clin. Invest. 100, 2562-2667.
-
(1997)
J. Clin. Invest
, vol.100
, pp. 2562-2667
-
-
Crawford, A.R.1
Smith, A.J.2
Hatch, V.C.3
Oude Elferink, R.P.4
Borst, P.5
Crawford, J.M.6
-
69
-
-
34250198653
-
Bile salts regulate proliferation and apoptosis of liver cells by modulating the IGF1 system
-
Drudi Metalli, V., Mancino, M. G., Mancino, A., Torrice, A., Gatto, M., Attili, A. F., Alpini, G. and Alvaro, D. (2007). Bile salts regulate proliferation and apoptosis of liver cells by modulating the IGF1 system. Dig. Liver Dis. 39, 654-662.
-
(2007)
Dig. Liver Dis
, vol.39
, pp. 654-662
-
-
Drudi Metalli, V.1
Mancino, M.G.2
Mancino, A.3
Torrice, A.4
Gatto, M.5
Attili, A.F.6
Alpini, G.7
Alvaro, D.8
-
70
-
-
0037304235
-
Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium
-
Chignard, N., Mergey, M., Veissiere, D., Poupon, R., Capeau, J., Parc, R., Paul, A. and Housset, C. (2003). Bile salts potentiate adenylyl cyclase activity and cAMP-regulated secretion in human gallbladder epithelium. Am. J. Physiol. Gastrointest. Liver Physiol. 284, G205-212.
-
(2003)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.284
-
-
Chignard, N.1
Mergey, M.2
Veissiere, D.3
Poupon, R.4
Capeau, J.5
Parc, R.6
Paul, A.7
Housset, C.8
-
71
-
-
0026642449
-
Gallbladder mucosal function: Studies in absorption and secretion in humans and in dog gallbladder epithelium
-
Igimi, H., Yamamoto, F. and Lee, S. P. (1992). Gallbladder mucosal function: studies in absorption and secretion in humans and in dog gallbladder epithelium. Am. J. Physiol. 263, G69-74.
-
(1992)
Am. J. Physiol
, vol.263
-
-
Igimi, H.1
Yamamoto, F.2
Lee, S.P.3
-
72
-
-
34447102461
-
Enhancement of dietary protein digestion by conjugated bile acids
-
Gass, J., Vora, H., Hofmann, A. F., Gray, G. M. and Khosla, C. (2007). Enhancement of dietary protein digestion by conjugated bile acids. Gastroenterology 133, 16-23.
-
(2007)
Gastroenterology
, vol.133
, pp. 16-23
-
-
Gass, J.1
Vora, H.2
Hofmann, A.F.3
Gray, G.M.4
Khosla, C.5
-
73
-
-
33645230000
-
How bile acids confer gut mucosal protection against bacteria
-
Hofmann, A. F. and Eckmann, L. (2006). How bile acids confer gut mucosal protection against bacteria. Proc. Natl. Acad. Sci. U. S. A. 103, 4333-4334.
-
(2006)
Proc. Natl. Acad. Sci. U. S. A
, vol.103
, pp. 4333-4334
-
-
Hofmann, A.F.1
Eckmann, L.2
-
74
-
-
33846162297
-
Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships
-
Keely, S. J., Scharl, M. M., Bertelsen, L. S., Hagey, L. R., Barrett, K. E. and Hofmann, A. F. (2007). Bile acid-induced secretion in polarized monolayers of T84 colonic epithelial cells: Structure-activity relationships. Am. J. Physiol. Gastrointest. Liver Physiol. 292, G290-297.
-
(2007)
Am. J. Physiol. Gastrointest. Liver Physiol
, vol.292
-
-
Keely, S.J.1
Scharl, M.M.2
Bertelsen, L.S.3
Hagey, L.R.4
Barrett, K.E.5
Hofmann, A.F.6
-
75
-
-
31444454037
-
Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation
-
Watanabe, M., Houten, S. M., Mataki, C., Christoffolete, M. A., Kim, B. W. Sato, H., Messaddeq, N., Harney, J. W., Ezaki, O., Kodama, T., Schoonjans, K., Blanco, A. C., and Auwerx, J. (2006). Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation. Nature 439, 484-489.
-
(2006)
Nature
, vol.439
, pp. 484-489
-
-
Watanabe, M.1
Houten, S.M.2
Mataki, C.3
Christoffolete, M.A.4
Kim, B.W.5
Sato, H.6
Messaddeq, N.7
Harney, J.W.8
Ezaki, O.9
Kodama, T.10
Schoonjans, K.11
Blanco, A.C.12
Auwerx, J.13
-
76
-
-
34247177532
-
Mutations in bile salt export pump (ABCB11) in two children with progressive familial intrahepatic cholestasis and cholangiocarcinoma
-
Scheimann, A. O., Strautnieks, S. S., Knisely, A. S., Byrne, J. A., Thompson, R. J. and Finegold, M. J. (2007). Mutations in bile salt export pump (ABCB11) in two children with progressive familial intrahepatic cholestasis and cholangiocarcinoma. J. Pediatr. 150, 556-559.
-
(2007)
J. Pediatr
, vol.150
, pp. 556-559
-
-
Scheimann, A.O.1
Strautnieks, S.S.2
Knisely, A.S.3
Byrne, J.A.4
Thompson, R.J.5
Finegold, M.J.6
-
77
-
-
50249091673
-
Early growth response factor-1 is critical for cholestatic liver injury
-
Kim, N. D., Moon, J-O., Slitt, A. L. and Copple, B. L. (2006). Early growth response factor-1 is critical for cholestatic liver injury. Toxicol. Sci. 20, 1-10.
-
(2006)
Toxicol. Sci
, vol.20
, pp. 1-10
-
-
Kim, N.D.1
Moon, J.-O.2
Slitt, A.L.3
Copple, B.L.4
-
78
-
-
0019519798
-
Altered bile acid metabolismin primary biliary cirrhosis
-
Raedsch, R., Lauterburg, B. H. and Hofmann, A. F. (1981). Altered bile acid metabolismin primary biliary cirrhosis. Dig. Dis. Sci. 26, 394-401.
-
(1981)
Dig. Dis. Sci
, vol.26
, pp. 394-401
-
-
Raedsch, R.1
Lauterburg, B.H.2
Hofmann, A.F.3
-
79
-
-
0018956463
-
Bile acids and their sulphated and glucuronidated derivatives in bile, plasma, and urine of children with intrahepatic cholestasis: Effects of phenobarbital treatment
-
Stiehl, A., Becker, M., Czygan, P., Frohling, W., Kommerell, B., Rotthauwe, H. W. and Senn, M. (1980). Bile acids and their sulphated and glucuronidated derivatives in bile, plasma, and urine of children with intrahepatic cholestasis: effects of phenobarbital treatment. Eur. J. Clin. Invest. 10, 307-316.
-
(1980)
Eur. J. Clin. Invest
, vol.10
, pp. 307-316
-
-
Stiehl, A.1
Becker, M.2
Czygan, P.3
Frohling, W.4
Kommerell, B.5
Rotthauwe, H.W.6
Senn, M.7
-
80
-
-
0344586817
-
Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein
-
Wang, R., Lam, P., Liu, L., Forrest, D., Yousef, I. M., Mignault, D., Phillips, M. J. and Ling, V. (2003). Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein. Hepatology 38, 1489-1499.
-
(2003)
Hepatology
, vol.38
, pp. 1489-1499
-
-
Wang, R.1
Lam, P.2
Liu, L.3
Forrest, D.4
Yousef, I.M.5
Mignault, D.6
Phillips, M.J.7
Ling, V.8
-
81
-
-
35248893940
-
Ursodeoxycholic acid for the treatment of primary biliary cirrhosis
-
Lindor, K. (2007). Ursodeoxycholic acid for the treatment of primary biliary cirrhosis. N. Engl. J. Med. 357, 1524-1529.
-
(2007)
N. Engl. J. Med
, vol.357
, pp. 1524-1529
-
-
Lindor, K.1
-
82
-
-
33646548609
-
Nasobiliary drainage for cholestatic pruritus
-
Hofmann, A. F. and Huet, P. M. (2006). Nasobiliary drainage for cholestatic pruritus. Hepatology 43, 1170-1171.
-
(2006)
Hepatology
, vol.43
, pp. 1170-1171
-
-
Hofmann, A.F.1
Huet, P.M.2
-
83
-
-
3142729446
-
Extracorporeal albumin dialysis: A procedure for prolonged relief of intractable pruritus in patients with primary biliary cirrhosis
-
Pares, A., Cisneros, L., Salmeron, J. M., Caballeria, L., Mas, A., Torras, A. and Rodes, J. (2004). Extracorporeal albumin dialysis: a procedure for prolonged relief of intractable pruritus in patients with primary biliary cirrhosis. Am. J. Gastroenterol 99, 1105-1110.
-
(2004)
Am. J. Gastroenterol
, vol.99
, pp. 1105-1110
-
-
Pares, A.1
Cisneros, L.2
Salmeron, J.M.3
Caballeria, L.4
Mas, A.5
Torras, A.6
Rodes, J.7
-
84
-
-
33947409205
-
Sertraline as a first-line treatment for cholestatic pruritus
-
Mayo, M. J., Handem, I., Saldana, S., Jacobe, H., Getachew, Y. and Rush, A. J. (2007). Sertraline as a first-line treatment for cholestatic pruritus. Hepatology 45, 666-674.
-
(2007)
Hepatology
, vol.45
, pp. 666-674
-
-
Mayo, M.J.1
Handem, I.2
Saldana, S.3
Jacobe, H.4
Getachew, Y.5
Rush, A.J.6
-
85
-
-
33745395997
-
Bile acids and Barrett's oesophagus: A sine qua non or coincidence?
-
Sital, R. R., Kusters, J. G., De Rooij, F. W., Kuipers, E. J. and Siersema, P. D. (2006). Bile acids and Barrett's oesophagus: a sine qua non or coincidence? Scand. J. Gastroenterol. Suppl. 11-17.
-
(2006)
Scand. J. Gastroenterol. Suppl
, pp. 11-17
-
-
Sital, R.R.1
Kusters, J.G.2
De Rooij, F.W.3
Kuipers, E.J.4
Siersema, P.D.5
-
86
-
-
0032965548
-
Toxic bile acids in gastro-oesophageal reflux disease: Influence of gastric acidity
-
Nehra, D., Howell, P., Williams, C. P., Pye, J. K. and Beynon, J. (1999). Toxic bile acids in gastro-oesophageal reflux disease: influence of gastric acidity. Gut 44, 598-602.
-
(1999)
Gut
, vol.44
, pp. 598-602
-
-
Nehra, D.1
Howell, P.2
Williams, C.P.3
Pye, J.K.4
Beynon, J.5
-
87
-
-
0022400911
-
Ursodeoxycholic acid treatment of bile reflux gastritis
-
Stefaniwsky, A. B., Tint, G. S., Speck, J., Shefer, S. and Salen, G. (1985). Ursodeoxycholic acid treatment of bile reflux gastritis. Gastroenterology 89, 1000-1004.
-
(1985)
Gastroenterology
, vol.89
, pp. 1000-1004
-
-
Stefaniwsky, A.B.1
Tint, G.S.2
Speck, J.3
Shefer, S.4
Salen, G.5
-
88
-
-
0020347014
-
Derivation de la bile dans l'ileon terminal chez le porc: Effet sur le niveau de secretion des acides biliares et sur l'útilisation digestive du regime.
-
Juste, C. and Corring, T. (1982). Derivation de la bile dans l'ileon terminal chez le porc: effet sur le niveau de secretion des acides biliares et sur l'útilisation digestive du regime. Reprod. Nutr. Develop. 22, 75-80.
-
(1982)
Reprod. Nutr. Develop
, vol.22
, pp. 75-80
-
-
Juste, C.1
Corring, T.2
-
89
-
-
0015356825
-
Bile acid metabolism in patients with cirrhosis. II. Cholic and chenodeoxycholic acid metabolism
-
Vlahcevic, Z. R., Juttijudata, P., Bell, C. C., Jr. and Swell, L. (1972). Bile acid metabolism in patients with cirrhosis. II. Cholic and chenodeoxycholic acid metabolism. Gastroenterology 62, 1174-1181.
-
(1972)
Gastroenterology
, vol.62
, pp. 1174-1181
-
-
Vlahcevic, Z.R.1
Juttijudata, P.2
Bell Jr., C.C.3
Swell, L.4
-
90
-
-
0020539554
-
Hepatic secretion of bilirubin and biliary lipids in patients with alcoholic cirrhosis of the liver
-
Raedsch, R., Stiehl, A., Gundert-Remy, U., Walker, S., Sieg, A., Czygan, P. and Kommerell, B. (1983). Hepatic secretion of bilirubin and biliary lipids in patients with alcoholic cirrhosis of the liver. Digestion 26, 80-88.
-
(1983)
Digestion
, vol.26
, pp. 80-88
-
-
Raedsch, R.1
Stiehl, A.2
Gundert-Remy, U.3
Walker, S.4
Sieg, A.5
Czygan, P.6
Kommerell, B.7
-
91
-
-
0019507465
-
Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: The National Cooperative Gallstone Study. A controlled trial of efficacy and safety
-
Schoenfield, L. J. and Lachin, J. M. (1981). Chenodiol (chenodeoxycholic acid) for dissolution of gallstones: the National Cooperative Gallstone Study. A controlled trial of efficacy and safety. Ann. Intern. Med. 95, 257-282.
-
(1981)
Ann. Intern. Med
, vol.95
, pp. 257-282
-
-
Schoenfield, L.J.1
Lachin, J.M.2
-
92
-
-
0020560612
-
Treatment of constipation with chenodeoxycholic acid
-
Bazzoli, F., Malavolti, M., Petronelli, A., Barbara, L. and Roda, E. (1983). Treatment of constipation with chenodeoxycholic acid. J. Int. Med. Res. 11, 120-123.
-
(1983)
J. Int. Med. Res
, vol.11
, pp. 120-123
-
-
Bazzoli, F.1
Malavolti, M.2
Petronelli, A.3
Barbara, L.4
Roda, E.5
-
93
-
-
50249116281
-
-
J. Ped. Gastro. Nutr, in press
-
Hofmann, A. F., Loening-Baucke, V., Lavine, J. E., Hagey, L. R., Steinbach, J. H., Packard, C. A., Griffin, T. L. and Chatfield, D. A. (2007). Altered Bile Acid Metabolism in Childhood Functional Constipation: Inactivation of Secretory Bile Acids in a Subset of Patients. J. Ped. Gastro. Nutr. (in press)
-
(2007)
Altered Bile Acid Metabolism in Childhood Functional Constipation: Inactivation of Secretory Bile Acids in a Subset of Patients
-
-
Hofmann, A.F.1
Loening-Baucke, V.2
Lavine, J.E.3
Hagey, L.R.4
Steinbach, J.H.5
Packard, C.A.6
Griffin, T.L.7
Chatfield, D.A.8
-
94
-
-
0020526708
-
Effect of colonic perfusion with sulfated and nonsulfated bile acids on mucosal structure and function in the rat
-
Breuer, N. F., Rampton, D. S., Tammar, A., Murphy, G. M. and Dowling, R. H. (1983). Effect of colonic perfusion with sulfated and nonsulfated bile acids on mucosal structure and function in the rat. Gastroenterology 84, 969-977.
-
(1983)
Gastroenterology
, vol.84
, pp. 969-977
-
-
Breuer, N.F.1
Rampton, D.S.2
Tammar, A.3
Murphy, G.M.4
Dowling, R.H.5
-
95
-
-
0026610361
-
Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine
-
Lillienau, J., Schteingart, C. D. and Hofmann, A. F. (1992). Physicochemical and physiological properties of cholylsarcosine. A potential replacement detergent for bile acid deficiency states in the small intestine. J. Clin. Invest. 89, 420-431.
-
(1992)
J. Clin. Invest
, vol.89
, pp. 420-431
-
-
Lillienau, J.1
Schteingart, C.D.2
Hofmann, A.F.3
-
96
-
-
0027416705
-
Cholylsarcosine, a new bile acid analogue: Metabolism and effect on biliary secretion in humans
-
Schmassmann, A., Fehr, H. F., Locher, J., Lillienau, J., Schteingart, C. D., Rossi, S. S. and Hofmann, A. F. (1993). Cholylsarcosine, a new bile acid analogue: metabolism and effect on biliary secretion in humans. Gastroenterology 104, 1171-1181.
-
(1993)
Gastroenterology
, vol.104
, pp. 1171-1181
-
-
Schmassmann, A.1
Fehr, H.F.2
Locher, J.3
Lillienau, J.4
Schteingart, C.D.5
Rossi, S.S.6
Hofmann, A.F.7
-
97
-
-
0032921262
-
Conjugated bile acid replacement therapy for short-bowel syndrome
-
Gruy-Kapral, C., Little, K. H., Fordtran, J. S., Meziere, T. L., Hagey, L. R. and Hofmann, A. F. (1999). Conjugated bile acid replacement therapy for short-bowel syndrome. Gastroenterology 116, 15-21.
-
(1999)
Gastroenterology
, vol.116
, pp. 15-21
-
-
Gruy-Kapral, C.1
Little, K.H.2
Fordtran, J.S.3
Meziere, T.L.4
Hagey, L.R.5
Hofmann, A.F.6
-
98
-
-
3342918935
-
Conjugated bile acid replacement therapy in short bowel syndrome patients with a residual colon
-
Kapral, C., Wewalka, F., Praxmarer, V., Lenz, K. and Hofmann, A. F. (2004). Conjugated bile acid replacement therapy in short bowel syndrome patients with a residual colon. Z. Gastroenterol. 42, 583-589.
-
(2004)
Z. Gastroenterol
, vol.42
, pp. 583-589
-
-
Kapral, C.1
Wewalka, F.2
Praxmarer, V.3
Lenz, K.4
Hofmann, A.F.5
-
99
-
-
0037372737
-
Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats
-
Lorenzo-Zuniga, V., Bartoli, R., Planas, R., Hofmann, A. F., Vinado, B., Hagey, L. R., Hernandez, J. M., Mane, J., Alvarez, M. A. Ausina, V., and Gassull, M. A. (2003). Oral bile acids reduce bacterial overgrowth, bacterial translocation, and endotoxemia in cirrhotic rats. Hepatology 37, 551-557.
-
(2003)
Hepatology
, vol.37
, pp. 551-557
-
-
Lorenzo-Zuniga, V.1
Bartoli, R.2
Planas, R.3
Hofmann, A.F.4
Vinado, B.5
Hagey, L.R.6
Hernandez, J.M.7
Mane, J.8
Alvarez, M.A.9
Ausina, V.10
Gassull, M.A.11
-
100
-
-
0019288919
-
Double-blind clinical evaluation of choleretic agents in patients with chronic liver disease and cholestasis syndromes]
-
Alkabes, M., Ancona, A., Palmieri, R., Palmieri, G. and Zambruno, E. (1980). Double-blind clinical evaluation of choleretic agents in patients with chronic liver disease and cholestasis syndromes]. Clin. Ter. 95, 637-654.
-
(1980)
Clin. Ter
, vol.95
, pp. 637-654
-
-
Alkabes, M.1
Ancona, A.2
Palmieri, R.3
Palmieri, G.4
Zambruno, E.5
-
101
-
-
0015495498
-
Dissolution of cholesterol gallstones by chenodeoxycholic acid
-
Danzinger, R. G., Hofmann, A. F., Schoenfield, L. J. and Thistle, J. L. (1972). Dissolution of cholesterol gallstones by chenodeoxycholic acid. N. Engl. J. Med. 286, 1-8.
-
(1972)
N. Engl. J. Med
, vol.286
, pp. 1-8
-
-
Danzinger, R.G.1
Hofmann, A.F.2
Schoenfield, L.J.3
Thistle, J.L.4
-
102
-
-
0032931977
-
Nonsurgical management of gallstone disease
-
Howard, D. E. and Fromm, H. (1999). Nonsurgical management of gallstone disease. Gastroenterol. Clin. North Am. 28, 133-144.
-
(1999)
Gastroenterol. Clin. North Am
, vol.28
, pp. 133-144
-
-
Howard, D.E.1
Fromm, H.2
-
103
-
-
0027998655
-
Pharmacology of ursodeoxycholic acid, an enterohepatic drug
-
Hofmann, A. F. (1994). Pharmacology of ursodeoxycholic acid, an enterohepatic drug. Scand. J. Gastroentero.l Suppl 204, 1-15.
-
(1994)
Scand. J. Gastroentero
, vol.50
, Issue.SUPPL. 204
, pp. 1-15
-
-
Hofmann, A.F.1
-
104
-
-
32944463445
-
Intrahepatic cholestasis of pregnancy: A randomized controlled trial comparing dexamethasone and ursodeoxycholic acid
-
Glantz, A., Marschall, H. U., Lammert, F. and Mattsson, L. A. (2005). Intrahepatic cholestasis of pregnancy: a randomized controlled trial comparing dexamethasone and ursodeoxycholic acid. Hepatology 42, 1399-1405.
-
(2005)
Hepatology
, vol.42
, pp. 1399-1405
-
-
Glantz, A.1
Marschall, H.U.2
Lammert, F.3
Mattsson, L.A.4
-
105
-
-
14944361288
-
The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis
-
Corpechot, C., Carrat, F., Bahr, A., Chretien, Y., Poupon, R. E. and Poupon, R. (2005). The effect of ursodeoxycholic acid therapy on the natural course of primary biliary cirrhosis. Gastroenterology 128, 297-303.
-
(2005)
Gastroenterology
, vol.128
, pp. 297-303
-
-
Corpechot, C.1
Carrat, F.2
Bahr, A.3
Chretien, Y.4
Poupon, R.E.5
Poupon, R.6
-
106
-
-
33744920572
-
Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis
-
Beuers, U. (2006). Drug insight: Mechanisms and sites of action of ursodeoxycholic acid in cholestasis. Nat. Clin. Pract. Gastroenterol. Hepatol. 3, 318-328.
-
(2006)
Nat. Clin. Pract. Gastroenterol. Hepatol
, vol.3
, pp. 318-328
-
-
Beuers, U.1
-
107
-
-
0037101810
-
6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity
-
Pellicciari, R., Fiorucci, S., Camaioni, E., Clerici, C., Costantino, G., Maloney, P. R., Morelli, A., Parks, D. J. and Willson, T. M. (2002). 6alpha-ethyl-chenodeoxycholic acid (6-ECDCA), a potent and selective FXR agonist endowed with anticholestatic activity. J Med Chem 45, 3569-3572.
-
(2002)
J Med Chem
, vol.45
, pp. 3569-3572
-
-
Pellicciari, R.1
Fiorucci, S.2
Camaioni, E.3
Clerici, C.4
Costantino, G.5
Maloney, P.R.6
Morelli, A.7
Parks, D.J.8
Willson, T.M.9
-
108
-
-
34347325158
-
Targeting farnesoid X receptor for liver and metabolic disorders
-
Fiorucci, S., Rizzo, G., Donini, A., Distrutti, E. and Santucci, L. (2007). Targeting farnesoid X receptor for liver and metabolic disorders. Trends. Mol. Med. 13, 298-309.
-
(2007)
Trends. Mol. Med
, vol.13
, pp. 298-309
-
-
Fiorucci, S.1
Rizzo, G.2
Donini, A.3
Distrutti, E.4
Santucci, L.5
-
109
-
-
32044462778
-
Novel biotransformation and physiological properties of norursodeoxycholic acid in man
-
Hofmann, A. F., Zakko, S. F., Lira, M., Clerici, C., Hagey, L. R., Lambert, K. K., Steinbach, J. H., Schteingart, C. D., Olinga, P. and Groothuis, G. M. (2005). Novel biotransformation and physiological properties of norursodeoxycholic acid in man. Hepatology 42, 1391-1398.
-
(2005)
Hepatology
, vol.42
, pp. 1391-1398
-
-
Hofmann, A.F.1
Zakko, S.F.2
Lira, M.3
Clerici, C.4
Hagey, L.R.5
Lambert, K.K.6
Steinbach, J.H.7
Schteingart, C.D.8
Olinga, P.9
Groothuis, G.M.10
-
110
-
-
33847064667
-
MDR3 (ABCB4) defects: A paradigm for the genetics of adult cholestatic syndromes
-
Trauner, M., Fickert, P. and Wagner, M. (2007). MDR3 (ABCB4) defects: a paradigm for the genetics of adult cholestatic syndromes. Semin. Liver. Dis. 27, 77-98.
-
(2007)
Semin. Liver. Dis
, vol.27
, pp. 77-98
-
-
Trauner, M.1
Fickert, P.2
Wagner, M.3
-
111
-
-
0026579784
-
Equilibrium and kinetic factors influencing bile sequestrant efficacy
-
Luner, P. E. and Amidon, G. L. (1992). Equilibrium and kinetic factors influencing bile sequestrant efficacy. Pharm. Res. 9, 670-676.
-
(1992)
Pharm. Res
, vol.9
, pp. 670-676
-
-
Luner, P.E.1
Amidon, G.L.2
-
112
-
-
0034911580
-
Colesevelam hydrochloride: A novel bile acid-binding resin
-
Aldridge, M. A. and Ito, M. K. (2001). Colesevelam hydrochloride: a novel bile acid-binding resin. Ann. Pharmacother. 35, 898-907.
-
(2001)
Ann. Pharmacother
, vol.35
, pp. 898-907
-
-
Aldridge, M.A.1
Ito, M.K.2
-
113
-
-
34347401852
-
Bile acid sequestrants and the treatment of type 2 diabetes mellitus
-
Staels, B. and Kuipers, F. (2007). Bile acid sequestrants and the treatment of type 2 diabetes mellitus. Drugs 67, 1383-1392.
-
(2007)
Drugs
, vol.67
, pp. 1383-1392
-
-
Staels, B.1
Kuipers, F.2
-
114
-
-
34948828109
-
Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1(7-38) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia
-
Suzuki, T., Oba, K., Igari, Y., Matsumura, N., Watanabe K., Futami-Suda, S., Yasuoka, H., Ouchi, M., Suzuki, K., Kigawa, Y. and Nakano, H., (2007). Colestimide lowers plasma glucose levels and increases plasma glucagon-like PEPTIDE-1(7-38) levels in patients with type 2 diabetes mellitus complicated by hypercholesterolemia. J. Nippon Med. Sci. 4, 338-343.
-
(2007)
J. Nippon Med. Sci
, vol.4
, pp. 338-343
-
-
Suzuki, T.1
Oba, K.2
Igari, Y.3
Matsumura, N.4
Watanabe, K.5
Futami-Suda, S.6
Yasuoka, H.7
Ouchi, M.8
Suzuki, K.9
Kigawa, Y.10
Nakano, H.11
-
115
-
-
24944565175
-
-
Tremont, S. J., Lee, L. F. Huang, H. C., Keller, B. T., Banerjeee, S. C., Both, S. R., Carpenter, A. J., Wang, C. C., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E, Mischke, D. A., Rather, N. P., Fletcher, T., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K. , Regina, K., Schuh, J.r., Smith, M. E., Trivedi, J. S. and Reitz, D. B. (2005). Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1). J. Med. Chem. 48, 5837-5852.
-
Tremont, S. J., Lee, L. F. Huang, H. C., Keller, B. T., Banerjeee, S. C., Both, S. R., Carpenter, A. J., Wang, C. C., Garland, D. J., Huang, W., Jones, C., Koeller, K. J., Kolodziej, S. A., Li, J., Manning, R. E., Mahoney, M. W., Miller, R. E, Mischke, D. A., Rather, N. P., Fletcher, T., Reinhard, E. J., Tollefson, M. B., Vernier, W. F., Wagner, G. M., Rapp, S. R., Beaudry, J., Glenn, K. , Regina, K., Schuh, J.r., Smith, M. E., Trivedi, J. S. and Reitz, D. B. (2005). Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 1). J. Med. Chem. 48, 5837-5852.
-
-
-
-
116
-
-
0041885458
-
Inappropriate ileal conservation of bile acids in cholestatic liver disease: Homeostasis gone awry
-
Hofmann, A. F. (2003). Inappropriate ileal conservation of bile acids in cholestatic liver disease: homeostasis gone awry. Gut 52, 1239-1241.
-
(2003)
Gut
, vol.52
, pp. 1239-1241
-
-
Hofmann, A.F.1
-
117
-
-
0141706384
-
Biliary diversion for progressive familial intrahepatic cholestasis: Improved liver morphology and bile acid profile
-
Kurbegov, A. C., Setchell, K. D., Haas, J. E., Mierau, G. W., Narkewicz, M., Bancroft, J. D., Karrer, F. and Sokol, R. J. (2003). Biliary diversion for progressive familial intrahepatic cholestasis: improved liver morphology and bile acid profile. Gastroenterology 125, 1227-1234.
-
(2003)
Gastroenterology
, vol.125
, pp. 1227-1234
-
-
Kurbegov, A.C.1
Setchell, K.D.2
Haas, J.E.3
Mierau, G.W.4
Narkewicz, M.5
Bancroft, J.D.6
Karrer, F.7
Sokol, R.J.8
-
118
-
-
0031893282
-
Ileal exclusion for Byler's disease: An alternative surgical approach with promising early results for pruritus
-
Hollands, C. M., Rivera-Pedrogo, F. J., Gonzalez-Vallina, R., Loret-de-Mola, O., Nahmad, M. and Burnweit, C. A. (1998). Ileal exclusion for Byler's disease: an alternative surgical approach with promising early results for pruritus. J. Pediatr. Surg. 33, 220-224.
-
(1998)
J. Pediatr. Surg
, vol.33
, pp. 220-224
-
-
Hollands, C.M.1
Rivera-Pedrogo, F.J.2
Gonzalez-Vallina, R.3
Loret-de-Mola, O.4
Nahmad, M.5
Burnweit, C.A.6
|