Differential expression of bile salt and organic anion transporters in developing rat liver

Journal of Hepatology

Volumn 41, Issue 2, 2004, Pages 201-208

  Gao, Bo ^a   St Pierre, Marie V ^a   Stieger, Bruno ^a   Meier, Peter J ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

Author keywords

Bile salt export pump; Bile salt transporters; Liver transporter ontogenesis; Multidrug resistance associated proteins; Na + taurocholate cotransport protein; Organic anion transporting polypeptides; Organic anions

Indexed keywords

BILE SALT; COTRANSPORTER; MULTIDRUG RESISTANCE PROTEIN 2; MULTIDRUG RESISTANCE PROTEIN 6; ORGANIC ANION TRANSPORTER; SODIUM ION; TAUROCHOLIC ACID;

ANALYTIC METHOD; ANIMAL TISSUE; ANION TRANSPORT; ARTICLE; CELL MEMBRANE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DEVELOPMENTAL STAGE; EMBRYO DEVELOPMENT; FEMALE; IMMUNOFLUORESCENCE MICROSCOPY; LIVER DEVELOPMENT; MALE; NONHUMAN; ONTOGENY; PHENOTYPIC VARIATION; POLARIZATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION;

AGING; ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; BILE ACIDS AND SALTS; COMPUTER SYSTEMS; EMBRYO; EMBRYONIC DEVELOPMENT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; ORGANIC ANION TRANSPORTERS; ORGANIC ANION TRANSPORTERS, SODIUM-DEPENDENT; RATS; RATS, SPRAGUE-DAWLEY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SYMPORTERS;

EID: 4444266366     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2004.04.029     Document Type: Article

References (51)

1. Meier P.J., Stieger B. Bile salt transporters. Annu Rev Physiol. 64:2002;635-661
2. Hagenbuch B., Meier P.J. Organic anion transporting polypeptides of the OATP/SLC21 family: phylogenetic classification as OATP/SLCO superfamily, new nomenclature and molecular/functional properties. Pflugers Arch-Eur J Physiol. 447:2004;653-665
3. Cattori V., van Montfoort J.E., Stieger B., Landmann L., Meijer D.K., Winterhalter K.H., et al. Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3. Pflugers Arch. 443:2001;188-195
4. Gerloff T., Stieger B., Hagenbuch B., Madon J., Landmann L., Roth J., et al. The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver. J Biol Chem. 273:1998;10046-10050
5. Noe J., Stieger B., Meier P.J. Functional expression of the canalicular bile salt export pump of human liver. Gastroenterology. 123:2002;1659-1666
6. Keppler D., Konig J. Hepatic secretion of conjugated drugs and endogenous substances. Semin Liver Dis. 20:2000;265-272
7. Borst P., Elferink R.O. Mammalian ABC transporters in health and disease. Annu Rev Biochem. 71:2002;537-592
8. Tomer G., Ananthanarayanan M., Weymann A., Balasubramanian N., Suchy F.J. Differential developmental regulation of rat liver canalicular membrane transporters bsep and mrp2. Pediatr Res. 53:2003;288-294
9. Zinchuk V.S., Okada T., Akimaru K., Seguchi H. Asynchronous expression and colocalization of Bsep and Mrp2 during development of rat liver. Am J Physiol. 282:2002;G540-G548
10. +-ATPase activity in fetal and neonatal rat liver plasma membrane vesicles. Am J Physiol. 251:1986;G665-G673
11. Boyer J.L., Hagenbuch B., Ananthanarayanan M., Suchy F., Stieger B., Meier P.J. Phylogenic and ontogenic expression of hepatocellular bile acid transport. Proc Natl Acad Sci USA. 90:1993;435-438
12. Hardikar W., Ananthanarayanan M., Suchy F.J. Differential ontogenic regulation of basolateral and canalicular bile acid transport proteins in rat liver. J Biol Chem. 270:1995;20841-20846
13. +-independent organic anion transporting polypeptide (oatp) in rat liver and kidney. J Hepatol. 25:1996;932-940
14. Angeletti R.H., Bergwerk A.J., Novikoff P.M., Wolkoff A.W. Dichotomous development of the organic anion transport protein in liver and choroid plexus. Am J Physiol. 275:1998;C882-C887
15. Guo G.L., Johnson D.R., Klaassen C.D. Postnatal expression and induction by pregnenolone-16alpha-carbonitrile of the organic anion-transporting polypeptide 2 in rat liver. Drug Metab Dispos. 30:2002;283-288
16. Li N., Hartley D.P., Cherrington N.J., Klaassen C.D. Tissue expression, ontogeny, and inducibility of rat organic anion transporting polypeptide 4. J Pharmacol Exp Ther. 301:2002;551-560
17. Bustin S.A. Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays. J Mol Endocrinol. 25:2000;169-193
18. Rippin S.J., Hagenbuch B., Meier P.J., Stieger B. Cholestatic expression pattern of sinusoidal and canalicular organic anion transport systems in primary cultured rat hepatocytes. Hepatology. 33:2001;776-782
19. +/Taurocholate cotransporting polypeptide in rat liver. Gastroenterology. 107:1994;1781-1787
20. Eckhardt U., Schroeder A., Stieger B., Höchli M., Landmann L., Tynes R., et al. Polyspecific substrate uptake by the hepatic organic anion transporter Oatp1 in stably transfected CHO cells. Am J Physiol. 276:1999;G1037-G1042
21. Reichel C., Gao B., Van Montfoort J., Cattori V., Rahner C., Hagenbuch B., et al. Localization and function of the organic anion-transporting polypeptide Oatp2 in rat liver. Gastroenterology. 117:1999;688-695
22. Madon J., Hagenbuch B., Landmann L., Meier P.J., Stieger B. Transport function and hepatocellular localization of mrp6 in rat liver. Mol Pharmacol. 57:2000;634-641
23. Quaroni A., Isselbacher K.J. Study of intestinal cell differentiation with monoclonal antibodies to intestinal cell surface components. Dev Biol. 111:1985;267-279
24. Wood R.L. An electron microscope study of developing bile canaliculi in the rat. Anat Rec. 151:1965;507-530
25. Arrese M., Ananthananarayanan M., Suchy F.J. Hepatobiliary transport: molecular mechanisms of development and cholestasis. Pediatr Res. 44:1998;141-147
26. Little J.M., Richey J.E., Van Thiel D.H., Lester R. Taurocholate pool size and distribution in the fetal rat. J Clin Invest. 63:1979;1042-1049
27. Klaassen C.D. Immaturity of the newborn rat's hepatic excretory function for ouabain. J Pharmacol Exp Ther. 183:1972;520-526
28. Cagen S.Z., Gibson J.E. Characteristics of hepatic excretory function during development. J Pharmacol Exp Ther. 210:1979;15-21
29. Klinger W. Biotransformation of drugs and other xenobiotics during postnatal development. Pharmacol Ther. 16:1982;377-429
30. Paulusma C.C., van Geer M.A., Evers R., Heijn M., Ottenhoff R., Borst P., et al. Canalicular multispecific organic anion transporter/multidrug resistance protein 2 mediates low-affinity transport of reduced glutathione. Biochem J. 338:1999;393-401
31. Ballatori N., Rebbeor J.F. Roles of MRP2 and oatp1 in hepatocellular export of reduced glutathione. Semin Liver Dis. 18:1998;377-387
32. Lichtlen P., Wang Y., Belser T., Georgiev O., Certa U., Sack R., et al. Target gene search for the metal-responsive transcription factor MTF-1. Nucleic Acids Res. 29:2001;1514-1523
33. Henderson G.I., Chen J.J., Schenker S. Ethanol, oxidative stress, reactive aldehydes, and the fetus. Front Biosci. 4:1999;D541-D550
34. Ji B., Ito K., Suzuki H., Sugiyama Y., Horie T. Multidrug resistance-associated protein 2 (MRP2) plays an important role in the biliary excretion of glutathione conjugates of 4-hydroxynonenal. Free Radic Biol Med. 33:2002;370-378
35. Ballatori N., Clarkson T.W. Developmental changes in the biliary excretion of methylmercury and glutathione. Science. 216:1982;61-63
36. Gerk P.M., Vore M. Regulation of expression of the multidrug resistance-associated protein 2 (MRP2) and its role in drug disposition. J Pharmacol Exp Ther. 302:2002;407-415
37. Johnson D.R., Guo G.L., Klaassen C.D. Expression of rat multidrug resistance protein 2 (Mrp2) in male and female rats during normal and pregnenolone-16alphacarbonitrile (PCN)-induced postnatal ontogeny. Toxicology. 178:2002;209-219
38. Mohan P., Ling S.C., Watkins J.B. Ontogeny of hepatobiliary secretion: role of glutathione. Hepatology. 19:1994;1504-1512
39. Suchy F.J., Bucuvalas J.C., Novak D.A. Determinants of bile formation during development: ontogeny of hepatic bile acid metabolism and transport. Semin Liver Dis. 7:1987;77-84
40. Shih D.Q., Bussen M., Sehayek E., Ananthanarayanan M., Shneider B.L., Suchy F.J., et al. Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism. Nat Genet. 27:2001;375-382
41. Parks D.J., Blanchard S.G., Bledsoe R.K., Chandra G., Consler T.G., Kliewer S.A., et al. Bile acids: natural ligands for an orphan nuclear receptor. Science. 284:1999;1365-1368
42. Makishima M., Okamoto A.Y., Repa J.J., Tu H., Learned R.M., Luk A., et al. Identification of a nuclear receptor for bile acids. Science. 284:1999;1362-1365
43. Kipp H., Arias I.M. Trafficking of canalicular ABC transporters in hepatocytes. Annu Rev Physiol. 64:2002;595-608
44. +/taurocholate cotransport and Ntcp translocation. J Biol Chem. 277:2002;28758-28783
45. Suchy F.J., Balistreri W.F. Uptake of taurocholate by hepatocytes isolated from developing rats. Pediatr Res. 16:1982;282-285
46. Suchy F.J., Courchene S.M., Blitzer B.L. Taurocholate transport by basolateral plasma membrane vesicles isolated from developing rat liver. Am J Physiol. 248:1985;G648-G654
47. Novak D.A., Sippel C.J., Ananthanarayanan M., Suchy F.J. Postnatal expression of the canalicular bile acid transport system of rat liver. Am J Physiol. 260:1991;G743-G751
48. Morris A.I., Little J.M., Lester R. Development of the bile acid pool in rats from neonatal life through puberty to maturity. Digestion. 28:1983;216-224
49. Massimi M., Lear S.R., Huling S.L., Jones A.L., Erickson S.K. Cholesterol 7alphahydroxylase (CYP7A): patterns of messenger RNA expression during rat liver development. Hepatology. 28:1998;1064-1072
50. Klaassen C.D. Hepatic excretory function in the newborn rat. J Pharmacol Exp Ther. 184:1973;721-728
51. Stacey N.H., Klaassen C.D. Uptake of ouabain by isolated hepatocytes from livers of developing rats. J Pharmacol Exp Ther. 211:1979;360-363