-
6
-
-
0344429365
-
High plasma HDL concentrations associated with enhanced atherosclerosis in transgenic mice overexpressing lecithin-cholesteryl acyltransferase
-
(1997)
Nat. Med.
, vol.3
, pp. 744-749
-
-
Berard, A.M.1
Foger, B.2
Remaley, A.3
Shamburek, R.4
Vaisman, B.L.5
Talley, G.6
Paigen, B.7
Hoyt R.F., Jr.8
Marcovina, S.9
Brewer H.B., Jr.10
Santamarina-Fojo, S.11
-
10
-
-
0030667676
-
Molecular basis of agonism and antagonism in the oestrogen receptor
-
(1997)
Nature
, vol.389
, pp. 753-758
-
-
Brzozowski, A.M.1
Pike, A.C.2
Dauter, Z.3
Hubbard, R.E.4
Bonn, T.5
Engstrom, O.6
Ohman, L.7
Greene, G.L.8
Gustafsson, J.A.9
Carlquist, M.10
-
15
-
-
0029046931
-
Identification of a nuclear receptor that is activated by farnesol metabolites
-
(1995)
Cell
, vol.81
, pp. 687-693
-
-
Forman, B.M.1
Goode, E.2
Chen, J.3
Oro, A.E.4
Bradley, D.J.5
Perlmann, T.6
Noonan, D.J.7
Burka, L.T.8
McMorris, T.9
Lamph, W.W.10
-
16
-
-
0033106423
-
Structure and chromosomal assignment of the sterol 12alpha-hydroxylase gene (CYP8B1) in human and mouse: Eukaryotic cytochrome P-450 gene devoid of introns
-
(1999)
Genomics
, vol.56
, pp. 184-196
-
-
Gafvels, M.1
Olin, M.2
Chowdhary, B.P.3
Raudsepp, T.4
Andersson, U.5
Persson, B.6
Jansson, M.7
Bjorkhem, I.8
Eggertsen, G.9
-
17
-
-
0033681001
-
Asymmetry in the PPARgamma/RXRalpha crystal structure reveals the molecular basis of heterodimerization among nuclear receptors
-
(2000)
Mol. Cell
, vol.5
, pp. 545-555
-
-
Gampe R.T., Jr.1
Montana, V.G.2
Lambert, M.H.3
Miller, A.B.4
Bledsoe, R.K.5
Milburn, M.V.6
Kliewer, S.A.7
Willson, T.M.8
Xu, H.E.9
-
18
-
-
0032540277
-
The sister of P-glycoprotein represents the canalicular bile salt export pump of mammalian liver
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10046-10050
-
-
Gerloff, T.1
Stieger, B.2
Hagenbuch, B.3
Madon, J.4
Landmann, L.5
Roth, J.6
Hofmann, A.F.7
Meier, P.J.8
-
19
-
-
0033637121
-
A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis
-
in press
-
(2000)
Mol. Cell
-
-
Goodwin, B.1
Jones, S.A.2
Price, R.R.3
Watson, M.A.4
McKee, D.D.5
Moore, L.B.6
Galardi, C.7
Wilson, J.G.8
Lewis, M.C.9
Roth, M.E.10
-
21
-
-
0033570028
-
Identification of a bile acidresponsive element in the human ileal bile acid-binding protein gene. Involvement of the famesoid X receptor/9-cis-retinoic acid receptor heterodimer
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 29749-29754
-
-
Grober, J.1
Zaghini, I.2
Fujii, H.3
Jones, S.A.4
Kliewer, S.A.5
Willson, T.M.6
Ono, T.7
Besnard, P.8
-
28
-
-
0032711405
-
Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis
-
(1999)
Gastroenterology
, vol.117
, pp. 1370-1379
-
-
Jansen, P.L.1
Strautnieks, S.S.2
Jacquemin, E.3
Hadchouel, M.4
Sokal, E.M.5
Hooiveld, G.J.6
Koning, J.H.7
De Jager-Krikken, A.8
Kuipers, F.9
Stellaard, F.10
-
32
-
-
0030008349
-
Efficient in vivo manipulation of mouse genomic sequences at the zygote stage
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 5860-5865
-
-
Lakso, M.1
Pichel, J.G.2
Gorman, J.R.3
Sauer, B.4
Okamoto, Y.5
Lee, E.6
Alt, F.W.7
Westphal, H.8
-
34
-
-
0034107017
-
Hepatic lipase deficiency decreases the selective uptake of HDL-cholesteryl esters in vivo
-
(2000)
J. Lipid Res.
, vol.41
, pp. 667-672
-
-
Lambert, G.1
Amar, M.J.2
Martin, P.3
Fruchart-Najib, J.4
Foger, B.5
Shamburek, R.D.6
Brewer H.B., Jr.7
Santamarina-Fojo, S.8
-
35
-
-
0028997684
-
Targeted disruption of the alpha isoform of the peroxisome proliferetor-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferetors
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3012-3022
-
-
Lee, S.S.1
Pineau, T.2
Drego, J.3
Lee, E.J.4
Owens, J.W.5
Kroetz, D.L.6
Fernandez-Salguero, P.M.7
Westphal, H.8
Gonzalez, F.J.9
-
37
-
-
14444285707
-
Activation of the nuclear receptor LXR by oxysterols defines a new hormone response pathway
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 3137-3140
-
-
Lehmann, J.M.1
Kliewer, S.A.2
Moore, L.B.3
Smith-Oliver, T.A.4
Oliver, B.B.5
Su, J.L.6
Sundseth, S.S.7
Winegar, D.A.8
Blanchard, D.E.9
Spencer, T.A.10
Willson, T.M.11
-
40
-
-
0033591297
-
Identification of a nuclear receptor for bile acids
-
(1999)
Science
, vol.284
, pp. 1362-1365
-
-
Makishima, M.1
Okamoto, A.Y.2
Repa, J.J.3
Tu, H.4
Leamed, R.M.5
Luk, A.6
Hull, M.V.7
Lustig, K.D.8
Mangelsdorf, D.J.9
Shan, B.10
-
42
-
-
0012473279
-
The nuclear receptor superfamily: The second decade
-
(1995)
Cell
, vol.83
, pp. 835-839
-
-
Mangelsdorf, D.J.1
Thummel, C.2
Beato, M.3
Herrlich, P.4
Schutz, G.5
Umesono, K.6
Blumberg, B.7
Kastner, P.8
Mark, M.9
Chambon, P.10
Evans, R.M.11
-
43
-
-
0033588227
-
Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23963-23968
-
-
Miyata, M.1
Kudo, G.2
Lee, Y.H.3
Yang, T.J.4
Gelboin, H.V.5
Fernandez-Salguero, P.6
Kimura, S.7
Gonzalez, F.J.8
-
45
-
-
0032505096
-
Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-gamma
-
(1998)
Nature
, vol.395
, pp. 137-143
-
-
Nolte, R.T.1
Wisely, G.B.2
Westin, S.3
Cobb, J.E.4
Lambert, M.H.5
Kurokawa, R.6
Rosenfeld, M.G.7
Willson, T.M.8
Glass, C.K.9
Milbum, M.V.10
-
46
-
-
0032527612
-
Cholesterol lowering in low density lipoprotein receptor knockout mice overexpressing apolipoprotein E
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 386-394
-
-
Osuga, J.1
Yonemoto, M.2
Yamada, N.3
Shimano, H.4
Yagyu, H.5
Ohashi, K.6
Harada, K.7
Kamei, T.8
Yazaki, Y.9
Ishibashi, S.10
-
47
-
-
0033591387
-
Bite acids: Natural ligands for an orphan nuclear receptor
-
(1999)
Science
, vol.284
, pp. 1365-1368
-
-
Parks, D.J.1
Blanchard, S.G.2
Bledsoe, R.K.3
Chandra, G.4
Consler, T.G.5
Kliewer, S.A.6
Stimmel, J.B.7
Willson, T.M.8
Zavacki, A.M.9
Moore, D.D.10
Lehmann, J.M.11
-
50
-
-
0033572656
-
Molecular determinants of nuclear receptor-corepressor interaction
-
(1999)
Genes Dev.
, vol.13
, pp. 3198-3208
-
-
Perissi, V.1
Staszewski, L.M.2
McInerney, E.M.3
Kurokawa, R.4
Krones, A.5
Rose, D.W.6
Lambert, M.H.7
Milburn, M.V.8
Glass, C.K.9
Rosenfeld, M.G.10
-
54
-
-
0030862412
-
Cathepsin B contributes to bile salt-induced apoptosis of rat hepatocytes
-
(1997)
Gastroenterology
, vol.113
, pp. 1714-1726
-
-
Roberts, L.R.1
Kurosawa, H.2
Bronk, S.F.3
Fesmier, P.J.4
Agellon, L.B.5
Leung, W.Y.6
Mao, F.7
Gores, G.J.8
-
56
-
-
0032961354
-
Characterization, cDNA cloning, and functional expression of mouse ileal sodium-dependent bile acid transporter
-
(1999)
J. Biochem.
, vol.125
, pp. 846-851
-
-
Saeki, T.1
Matoba, K.2
Furukawa, H.3
Kirifuji, K.4
Kanamoto, R.5
Iwami, K.6
-
63
-
-
0026808475
-
Sequence complementarity between the 5'-terminal regions of mRNAs for rat mitochondrial cytochrome P-450c27/25 and a growth hormone-inducible serine protease inhibitor. A possible gene overlap
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 2421-2428
-
-
Shayiq, R.M.1
Avadhani, N.G.2
-
64
-
-
0027363563
-
Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
-
(1993)
Cell
, vol.75
, pp. 451-462
-
-
Smit, J.J.1
Schinkel, A.H.2
Oude Elferink, R.P.3
Groen, A.K.4
Wagenaar, E.5
Van Deemter, L.6
Mol, C.A.7
Ottenhoff, R.8
Van der Lugt, N.M.9
Van Roon, M.A.10
-
66
-
-
0030869696
-
Identification of a locus for progressive familial intrahepatic cholestasis PFIC2 on chromosome 2q24
-
(1997)
Am. J. Hum. Genet.
, vol.61
, pp. 630-633
-
-
Strautnieks, S.S.1
Kagalwalla, A.F.2
Tanner, M.S.3
Knisely, A.S.4
Bull, L.5
Freimer, N.6
Kocoshis, S.A.7
Gardiner, R.M.8
Thompson, R.J.9
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