Preimplantation embryogenesis

Knobil and Neill's Physiology of Reproduction

Volumn , Issue , 2006, Pages 261-310

  Burns, Kathleen H ^a   Matzuk, Martin M ^b  

^a JOHNS HOPKINS HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 68149099329     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012515400-0/50012-9     Document Type: Chapter

References (419)

1. Pinto-Correia C. The Ovary of Eve: Egg and Sperm and Preformation 1997, The University of Chicago Press, Philadelphia.
2. Biggers J.D. Walter Heape, F.R.S.: a pioneer in reproductive biology. Centenary of his embryo transfer experiments. J. Reprod. Fertil. 1991, 93:173-186.
3. Robertson E., Bradley A., Kuehn M., Evans M. Germ-line transmission of genes introduced into cultured pluripotential cells by retroviral vector. Nature 1986, 323:445-448.
4. Thomas K.R., Capecchi M.R. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 1987, 51:503-512.
5. Capecchi M.R. Targeted gene replacement. Sci. Am. 1994, 270:52-59.
6. Burns K., DeMayo F.J., Matzuk M.M. Transgenic technology, cloning and germ cell transplantation. Molecular Biology in Reproductive Medicine 2002, 169-195. Parthenon Publishing. 2nd ed. B.C.J.M. Fauser (Ed.).
7. Bouniol-Baly C., Hamraoui L., Guibert J., Beaujean N., Szollosi M.S., Debey P. Differential transcriptional activity associated with chromatin configuration in fully grown mouse germinal vesicle oocytes. Biol. Reprod. 1999, 60:580-587.
8. Ostermeier G.C., Miller D., Huntriss J.D., Diamond M.P., Krawetz S.A. Reproductive biology: delivering spermatozoan RNA to the oocyte. Nature 2004, 429:154.
9. Goddard M.J., Pratt H.P. Control of events during early cleavage of the mouse embryo: an analysis of the "2-cell block.". J. Embryol. Exp. Morphol. 1983, 73:111-133.
10. Wu X., Viveiros M., Eppig J., Bai Y., Fitzpatrick S., Matzuk M.M. Zygote arrest 1 (Zar1) is a novel maternal-effect gene critical for the oocyte-to-embryo transition. Nat. Genet. 2003, 33:187-191.
11. Burns K.H., Viveiros M.M., Ren Y., Wang P., DeMayo F.J., Frail D.E., Eppig J.J., Matzuk M.M. Roles of NPM2 in chromatin and nucleolar organization in oocytes and embryos. Science 2003, 300:633-636.
12. Diatchenko L., Lau Y.F., Campbell A.P., Chenchik A., Moqadam F., Huang B., Lukyanov S., Lukyanov K., Gurskaya N., Sverdlov E.D., Siebert P.D. Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc. Natl. Acad. Sci. U S A 1996, 93:6025-6030. 1996.
13. Philpott A., Leno G.H. Nucleoplasmin remodels sperm chromatin in Xenopus egg extracts. Cell 1992, 69:759-767.
14. Philpott A., Leno G.H., Laskey R.A. Sperm decondensation in Xenopus egg cytoplasm is mediated by nucleoplasmin. Cell 1991, 65:569-578.
15. Earnshaw W.C., Honda B.M., Laskey R.A., Thomas J.O. Assembly of nucleosomes: the reaction involving X. laevis nucleoplasmin. Cell 1980, 21:373-383.
16. Wu X., Wang P., Brown C.A., Zilinski C.A., Matzuk M.M. Zygote arrest 1 (Zar1) is an evolutionarily conserved gene expressed in vertebrate ovaries. Biol. Reprod. 2003, 69:861-867.
17. Crevel G., Huikeshoven H., Cotterill S., Simon M., Wall J., Philpott A., Laskey R.A., McConnell M., Fisher P.A., Berrios M. Molecular and cellular characterization of CRP1, a Drosophila chromatin decondensation protein. J. Struct. Biol. 1997, 118:9-22.
18. Saitou M., Barton S.C., Surani M.A. A molecular programme for the specification of germ cell fate in mice. Nature 2002, 418:293-300.
19. Payer B., Saitou M., Barton S.C., Thresher R., Dixon J.P., Zahn D., Colledge W.H., Carlton M.B., Nakano T., Surani M.A. Stella is a maternal effect gene required for normal early development in mice. Curr. Biol. 2003, 13:2110-2117.
20. Tong Z.B., Gold L., Pfeifer K.E., Dorward H., Lee E., Bondy C.A., Dean J., Nelson L.M. Mater, a maternal effect gene required for early embryonic development in mice. Nat. Genet. 2000, 26:267-268.
21. Tong Z.B., Nelson L.M., Dean J. Mater encodes a maternal protein in mice with a leucine-rich repeat domain homologous to porcine ribonuclease inhibitor. Mamm. Genome 2000, 11:281-287.
22. Narducci, M. G., Fiorenza, M. T., Kang, S. M., Bevilacqua, A. Di Giacomo, M., Remotti, D., Picchio, M. C., Fidanza, V., Cooper, M. D., Croce, C. M., Mangia, F., and Russo, G. TCL1 participates in early embryonic development and is overexpressed in human seminomas. Proc. Natl. Acad. Sci. U S A 99, 11712-11717.
23. Howell C.Y., Bestor T.H., Ding F., Latham K.E., Mertineit C., Trasler J.M., Chaillet J.R. Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell 2001, 104:829-838.
24. Christians E., Davis A.A., Thomas S.D., Benjamin I.J. Maternal effect of Hsf1 on reproductive success. Nature 2000, 407:693-694.
25. Leader B., Lim H., Carabatsos M.J., Harrington A., Ecsedy J., Pellman D., Maas R., Leder P. Formin-2, polyploidy, hypofertility and positioning of the meiotic spindle in mouse oocytes. Nat. Cell. Biol. 2002, 4:921-928.
26. Yuan L., Liu J.G., Hoja M.R., Wilbertz J., Nordqvist K., Hoog C. Female germ cell aneuploidy and embryo death in mice lacking the meiosis-specific protein SCP3. Science 2002, 296:1115-1118.
27. Gurtu V.E., Verma S., Grossmann A.H., Liskay R.M., Skarnes W.C., Baker S.M. Maternal effect for DNA mismatch repair in the mouse. Genetics 2002, 160:271-277.
28. Hogan B., Beddington R., Costantini F., Lacy E. Manipulating the Mouse Embryo-A Laboratory Manual 1994, Cold Spring Harbor Laboratory Press.
29. Matzuk M.M., Kumar T.R., Shou W., Coerver K.A., Lau A.L., Behringer R.R., Finegold M.J. Transgenic models to study the roles of inhibins and activins in reproduction, oncogenesis, and development. Rec. Progr. Horm. Res. 1996, 51:123-157.
30. Eppig J.J., Wigglesworth K., Pendola F.L. The mammalian oocyte orchestrates the rate of ovarian follicular development. Proc. Natl. Acad. Sci. U S A 2002, 99:2890-2894.
31. Lewandoski M., Wassarman K.M., Martin G.R. Zp3-cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line. Curr. Biol. 1997, 7:148-151.
32. de Vries W.N., Binns L.T., Fancher K.S., Dean J., Moore R., Kemler R., Knowles B.B. Expression of Cre recombinase in mouse oocytes: a means to study maternal effect genes. Genesis 2000, 26:110-112.
33. Alfieri J.A., Martin A.D., Takeda J., Kondoh G., Myles D.G., Primakoff P. Infertility in female mice with an oocyte-specific knockout of GPI-anchored proteins. J. Cell. Sci. 2003, 116:2149-2155.
34. Lan Z.J., Gu P., Xu X., Jackson K.J., DeMayo F.J., O'Malley B.W., Cooney A.J. GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility. EMBO J. 2003, 22:4070-4081.
35. Erhardt S., Su I.H., Schneider R., Barton S., Bannister A.J., Perez-Burgos L., Jenuwein T., Kouzarides T., Tarakhovsky A., Surani M.A. Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development. Development 2003, 130:4235-4248.
36. Svoboda P., Stein P., Hayashi H., Schultz R.M. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference. Development 2000, 127:4147-4156.
37. Svoboda P., Stein P., Schultz R.M. RNAi in mouse oocytes and preimplantation embryos: effectiveness of hairpin dsRNA. Biochem. Biophys. Res. Commun. 2001, 287:1099-1104.
38. Kanzler B., Haas-Assenbaum A., Haas I., Morawiec L., Huber E., Boehm T. Morpholino oligonucleotidetriggered knockdown reveals a role for maternal E-cadherin during early mouse development. Mech. Dev. 2003, 120:1423-1432.
39. Siddall L.S., Barcroft L.C., Watson A.J. Targeting gene expression in the preimplantation mouse embryo using morpholino antisense oligonucleotides. Mol. Reprod. Dev. 2002, 63:413-421.
40. Schultz R.M., Wassarman P.M. Biochemical studies of mammalian oogenesis: protein synthesis during oocyte growth and meiotic maturation in the mouse. J. Cell. Sci. 1977, 24:167-194.
41. Cascio S.M., Wassarman P.M. Program of early development in the mammal: post-transcriptional control of a class of proteins synthesized by mouse oocytes and early embryos. Dev. Biol. 1982, 89:397-408.
42. Kuersten S., Goodwin E.B. The power of the 3′UTR: translational control and development. Nat. Rev. Genet. 2003, 4:626-637.
43. Hwang S.Y., Oh B., Knowles B.B., Solter D., Lee J.S. Expression of genes involved in mammalian meiosis during the transition from egg to embryo. Mol. Reprod. Dev. 2001, 59:144-158.
44. Gebauer F., Xu W., Cooper G.M., Richter J.D. Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse. EMBO J. 1994, 13:5712.
45. Fuchimoto D., Mizukoshi A., Schultz R.M., Sakai S., Aoki F. Posttranscriptional regulation of cyclin A1 and cyclin A2 during mouse oocyte meiotic maturation and preimplantation development. Biol. Reprod. 2001, 65:986-993.
46. Oh B., Hwang S.Y., Solter D., Knowles B.B. Spindlin, a major maternal transcript expressed in the mouse during the transition from oocyte to embryo. Development 1997, 124:493-503.
47. Tay J., Hodgman R., Sarkissian M., Richter J.D. Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003, 17:1457-1462.
48. Tay J., Richter J.D. Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev. Cell. 2001, 1:201-213.
49. Aoki F., Hara K.T., Schultz R.M. Acquisition of transcriptional competence in the 1-cell mouse embryo: requirement for recruitment of maternal mRNAs. Mol. Reprod. Dev. 2003, 64:270-274.
50. Wang Q., Latham K.E. Requirement for protein synthesis during embryonic genome activation in mice. Mol. Reprod. Dev. 1997, 47:265-270.
51. Rambhatla L., Latham K.E. Strain-specific progression of alpha-amanitin-treated mouse embryos beyond the two-cell stage. Mol. Reprod. Dev. 1995, 41:16-19.
52. Bouniol C., Nguyen E., Debey P. Endogenous transcription occurs at the 1-cell stage in the mouse embryo. Exp. Cell. Res. 1995, 218:57-62.
53. Aoki F., Worrad D.M., Schultz R.M. Regulation of transcriptional activity during the first and second cell cycles in the preimplantation mouse embryo. Dev. Biol. 1997, 181:296-307.
54. Davis W., De Sousa P.A., Schultz R.M. Transient expression of translation initiation factor eIF-4C during the 2-cell stage of the preimplantation mouse embryo: identification by mRNA differential display and the role of DNA replication in zygotic gene activation. Dev. Biol. 1996, 174:190-201.
55. Forlani S., Bonnerot C., Capgras S., Nicolas J.F. Relief of a repressed gene expression state in the mouse 1-cell embryo requires DNA replication. Development 1998, 125:3153-3166.
56. Vernet M., Bonnerot C., Briand P., Nicolas J.F. Changes in permissiveness for the expression of microinjected DNA during the first cleavages of mouse embryos. Mech. Dev. 1992, 36:129-139.
57. Latham K.E., Solter D., Schultz R.M. Acquisition of a transcriptionally permissive state during the 1-cell stage of mouse embryogenesis. Dev. Biol. 1992, 149:457-462.
58. Davis W., Schultz R.M. Role of the first round of DNA replication in reprogramming gene expression in the preimplantation mouse embryo. Mol. Reprod. Dev. 1997, 47:430-434.
59. Wiekowski M., Miranda M., DePamphilis M.L. Regulation of gene expression in preimplantation mouse embryos: effects of the zygotic clock and the first mitosis on promoter and enhancer activities. Dev. Biol. 1991, 147:403-414.
60. Prioleau M.N., Buckle R.S., Mechali M. Programming of a repressed but committed chromatin structure during early development. EMBO J. 1995, 14:5073-5084.
61. Bellier S., Chastant S., Adenot P., Vincent M., Renard J.P., Bensaude O. Nuclear translocation and carboxylterminal domain phosphorylation of RNA polymerase II delineate the two phases of zygotic gene activation in mammalian embryos. EMBO J. 1997, 16:6250-6262.
62. Bellier S., Dubois M.F., Nishida E., Almouzni G., Bensaude O. Phosphorylation of the RNA polymerase II largest subunit during Xenopus laevis oocyte maturation. Mol. Cell. Biol. 1997, 17:1434-1440.
63. Rossi D.J., Londesborough A., Korsisaari N., Pihlak A., Lehtonen E., Henkemeyer M., Makela T.P. Inability to enter S phase and defective RNA polymerase II CTD phosphorylation in mice lacking Mat1. EMBO J. 2001, 20:2844-2856.
64. Rossignol M., Kolb-Cheynel I., Egly J.M. Substrate specificity of the cdk-activating kinase (CAK) is altered upon association with TFIIH. EMBO J. 1997, 16:1628-1637.
65. Yankulov, K. Y., and Bentley, D. L. Regulation of CDK7 substrate specificity by MAT1 and TFIIH. EMBO J. 16, 1638-1646.
66. Ram P.T., Schultz R.M. Reporter gene expression in G2 of the 1-cell mouse embryo. Dev. Biol. 1993, 156:552-556.
67. Henery C.C., Miranda M., Wiekowski M., Wilmut I., DePamphilis M.L. Repression of gene expression at the beginning of mouse development. Dev. Biol. 1995, 169:448-460.
68. Adenot P.G., Mercier Y., Renard J.P., Thompson E.M. Differential H4 acetylation of paternal and maternal chromatin precedes DNA replication and differential transcriptional activity in pronuclei of 1-cell mouse embryos. Development 1997, 124:4615-4625.
69. Cowell I.G., Aucott R., Mahadevaiah S.K., Burgoyne P.S., Huskisson N., Bongiorni S., Prantera G., Fanti L., Pimpinelli S., Wu R., Gilbert D.M., Shi W., Fundele R., Morrison H., Jeppesen P., Singh P.B. Heterochromatin, HP1 and methylation at lysine 9 of histone H3 in animals. Chromosoma 2002, 111:22-36.
70. Jenuwein T., Allis C.D. Translating the histone code. Science 2001, 293:1074-1080.
71. Wiekowski M., Miranda M., DePamphilis M.L. Requirements for promoter activity in mouse oocytes and embryos distinguish paternal pronuclei from maternal and zygotic nuclei. Dev. Biol. 1993, 159:366-378.
72. Nothias J.Y., Miranda M., DePamphilis M.L. Uncoupling of transcription and translation during zygotic gene activation in the mouse. EMBO J. 1996, 15:5715-5725.
73. DePamphilis M.L., Kaneko K.J., Vassilev A. Activation of zygotic gene expression in mammals. Developmental Biology and Biochemistry 2002, Vol. 12:55-82. M. DePamphilis (Ed.).
74. Domashenko A.D., Latham K.E., Hatton K.S. Expression of myc-family, myc-interacting, and myc-target genes during preimplantation mouse development. Mol. Reprod. Dev. 1997, 47:57-65.
75. Sprinks M.T., Sellens M.H., Dealtry G.B., Fernandez N. Preimplantation mouse embryos express Mhc class I genes before the first cleavage division. Immunogenetics 1993, 38:35-40.
76. Wiekowski M., Miranda M., Nothias J.Y., DePamphilis M.L. Changes in histone synthesis and modification at the beginning of mouse development correlate with the establishment of chromatin mediated repression of transcription. J. Cell. Sci. 1997, 110:1147-1158. (Pt 10).
77. Schultz R.M., Davis W., Stein P., Svoboda P. Reprogramming of gene expression during preimplantation development. J. Exp. Zool. 1999, 285:276-282.
78. Spada F., Brunet A., Mercier Y., Renard J.P., Bianchi M.E., Thompson E.M. High mobility group 1 (HMG1) protein in mouse preimplantation embryos. Mech. Dev. 1998, 76:57-66.
79. Palmieri S.L., Peter W., Hess H., Scholer H.R. Oct-4 transcription factor is differentially expressed in the mouse embryo during establishment of the first two extraembryonic cell lineages involved in implantation. Dev. Biol. 1994, 166:259-267.
80. Martianov I., Viville S., Davidson I. RNA polymerase II transcription in murine cells lacking the TATA binding protein. Science 2002, 298:1036-1039.
81. Kaneko K.J., DePamphilis M.L. Regulation of gene expression at the beginning of mammalian development and the TEAD family of transcription factors. Dev. Genet. 1998, 22:43-55.
82. Worrad D.M., Schultz R.M. Regulation of gene expression in the preimplantation mouse embryo: temporal and spatial patterns of expression of the transcription factor Sp1. Mol. Reprod. Dev. 1997, 46:268-277.
83. Jumaa H., Wei G., Nielsen P.J. Blastocyst formation is blocked in mouse embryos lacking the splicing factor SRp20. Curr. Biol. 1999, 9:899-902.
84. Latham K.E., Rambhatla L., Hayashizaki Y., Chapman V.M. Stage-specific induction and regulation by genomic imprinting of the mouse U2afbp-rs gene during preimplantation development. Dev. Biol. 1995, 168:670-676.
85. Kim M., Geum D., Khang I., Park Y.M., Kang B.M., Lee K.A., Kim K. Expression pattern of HSP25 in mouse preimplantation embryo: heat shock responses during oocyte maturation. Mol. Reprod. Dev. 2002, 61:3-13.
86. Christians E., Campion E., Thompson E.M., Renard J.P. Expression of the HSP 70.1 gene, a landmark of early zygotic activity in the mouse embryo, is restricted to the first burst of transcription. Development 1995, 121:113-122.
87. Baran V., Brochard V., Renard J.P., Flechon J.E. Nopp 140 involvement in nucleologenesis of mouse preimplantation embryos. Mol. Reprod. Dev. 2001, 59:277-284.
88. Taylor K.D., Piko L. Expression of ribosomal protein genes in mouse oocytes and early embryos. Mol. Reprod. Dev. 1992, 31:182-188.
89. Sevigny G., Kothary R., Tremblay E., De Repentigny Y., Joly E.C., Bibor-Hardy V. The cytosolic chaperonin subunit TRiC-P5 begins to be expressed at the two-cell stage in mouse embryos. Biochem. Biophys. Res. Commun. 1995, 216:279-283.
90. Latham K.E., Rambhatla L. Expression of X-linked genes in androgenetic, gynogenetic, and normal mouse preimplantation embryos. Dev. Genet. 1995, 17:212-222.
91. Zuccotti M., Boiani M., Ponce R., Guizzardi S., Scandroglio R., Garagna S., Redi C.A. Mouse Xist expression begins at zygotic genome activation and is timed by a zygotic clock. Mol. Reprod. Dev. 2002, 61:14-20.
92. Zwingman T., Erickson R.P., Boyer T., Ao A. Transcription of the sex-determining region genes Sry and Zfy in the mouse preimplantation embryo. Proc. Natl. Acad. Sci. U S A 1993, 90:814-817.
93. Kigami D., Minami N., Takayama H., Imai H. MuERV-L is one of the earliest transcribed genes in mouse one-cell embryos. Biol. Reprod. 2003, 68:651-654.
94. Wang Q., Chung Y.G., deVries W.N., Struwe M., Latham K.E. Role of protein synthesis in the development of a transcriptionally permissive state in one-cell stage mouse embryos. Biol. Reprod. 2001, 65:748-754.
95. Conover J.C., Temeles G.L., Zimmermann J.W., Burke B., Schultz R.M. Stage-specific expression of a family of proteins that are major products of zygotic gene activation in the mouse embryo. Dev. Biol. 1991, 144:392-404.
96. Bachvarova R., De Leon V., Spiegelman I. Mouse egg ribosomes: evidence for storage in lattices. J. Embryol. Exp. Morphol. 1981, 62:153-164.
97. Thomas T., Voss A.K., Petrou P., Gruss P. The murine gene, Traube, is essential for the growth of preimplantation embryos. Dev. Biol. 2000, 227:324-342.
98. Fanciulli M., Bruno T., Di Padova M., De Angelis R., Iezzi S., Iacobini C., Floridi A., Passananti C. Identification of a novel partner of RNA polymerase II subunit 11, Che-1, which interacts with and affects the growth suppression function of Rb. Faseb. J. 2000, 14:904-912.
99. Matsson H., Davey E.J., Draptchinskaia N., Hamaguchi I., Ooka A., Leveen P., Forsberg E., Karlsson S., Dahl N. Targeted disruption of the ribosomal protein S19 gene is lethal prior to implantation. Mol. Cell. Biol. 2004, 24:4032-4037.
100. Marin M., Karis A., Visser P., Grosveld F., Philipsen S. Transcription factor Sp1 is essential for early embryonic development but dispensable for cell growth and differentiation. Cell 1997, 89:619-628.
101. Wang Q., Latham K.E. Translation of maternal messenger ribonucleic acids encoding transcription factors during genome activation in early mouse embryos. Biol. Reprod. 2000, 62:969-978.
102. Bleckmann S.C., Blendy J.A., Rudolph D., Monaghan A.P., Schmid W., Schutz G. Activating transcription factor 1 and CREB are important for cell survival during early mouse development. Mol. Cell. Biol. 2002, 22:1919-1925.
103. Rudolph D., Tafuri A., Gass P., Hammerling G.J., Arnold B., Schutz G. Impaired fetal T cell development and perinatal lethality in mice lacking the cAMP response element binding protein. Proc. Natl. Acad. Sci. U S A 1998, 95:4481-4486.
104. Ko M.S., Kitchen J.R., Wang X., Threat T.A., Hasegawa A., Sun T., Grahovac M.J., Kargul G.J., Lim M.K., Cui Y., Sano Y., Tanaka T., Liang Y., Mason S., Paonessa P.D., Sauls A.D., DePalma G.E., Sharara R., Rowe L.B., Eppig J., Morrell C., Doi H. Largescale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development 2000, 127:1737-1749.
105. Ma J., Svoboda P., Schultz R.M., Stein P. Regulation of zygotic gene activation in the preimplantation mouse embryo: global activation and repression of gene expression. Biol. Reprod. 2001, 64:1713-1721.
106. Pacheco-Trigon S., Hennequet-Antier C., Oudin J.F., Piumi F., Renard J.P., Duranthon V. Molecular characterization of genomic activities at the onset of zygotic transcription in mammals. Biol. Reprod. 2002, 67:1907-1918.
107. Martinez-Salas E., Linney E., Hassell J., DePamphilis M.L. The need for enhancers in gene expression first appears during mouse development with formation of the zygotic nucleus. Genes Dev. 1989, 3:1493-1506.
108. Martinez-Salas E., Cupo D.Y., DePamphilis M.L. The need for enhancers is acquired upon formation of a diploid nucleus during early mouse development. Genes Dev. 1988, 2:1115-1126.
109. Majumder S., Zhao Z., Kaneko K., DePamphilis M.L. Developmental acquisition of enhancer function requires a unique coactivator activity. EMBO J. 1997, 16:1721-1731.
110. Davis W., Schultz R.M. Developmental change in TATA-box utilization during preimplantation mouse development. Dev. Biol. 2000, 218:275-283.
111. Majumder S., DePamphilis M.L. TATA-dependent enhancer stimulation of promoter activity in mice is developmentally acquired. Mol. Cell. Biol. 1994, 14:4258-4268.
112. Latham K.E., Garrels J.I., Chang C., Solter D. Quantitative analysis of protein synthesis in mouse embryos. I. Extensive reprogramming at the one- and two-cell stages. Development 1991, 112:921-932.
113. Shi C.Z., Collins H.W., Garside W.T., Buettger C.W., Matschinsky F.M., Heyner S. Protein databases for compacted eight-cell and blastocyst-stage mouse embryos. Mol. Reprod. Dev. 1994, 37:34-47.
114. Kafri T., Ariel M., Brandeis M., Shemer R., Urven L., McCarrey J., Cedar H., Razin A. Developmental pattern of gene-specific DNA methylation in the mouse embryo and germ line. Genes Dev. 1992, 6:705-714.
115. Hajkova P., Erhardt S., Lane N., Haaf T., El-Maarri O., Reik W., Walter J., Surani MA. Epigenetic reprogramming in mouse primordial germ cells. Mech. Dev. 1998, 117:15-23.
116. Chen R.Z., Pettersson U., Beard C., Jackson-Grusby L., Jaenisch R. DNA hypomethylation leads to elevated mutation rates. Nature 1998, 395:89-93.
117. Szabo P.E., Mann J.R. Biallelic expression of imprinted genes in the mouse germ line: implications for erasure, establishment, and mechanisms of genomic imprinting. Genes Dev. 1995, 9:1857-1868.
118. Lucifero D., Mertineit C., Clarke H.J., Bestor T.H., Trasler J.M. Methylation dynamics of imprinted genes in mouse germ cells. Genomics 2002, 79:530-538.
119. Obata Y., Kaneko-Ishino T., Koide T., Takai Y., Ueda T., Domeki I., Shiroishi T., Ishino F., Kono T. Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development 1998, 125:1553-1560.
120. Oswald J., Engemann S., Lane N., Mayer W., Olek A., Fundele R., Dean W., Reik W., Walter J. Active demethylation of the paternal genome in the mouse zygote. Curr. Biol. 2000, 10:475-478.
121. Olek A., Walter J. The pre-implantation ontogeny of the H19 methylation imprint. Nat. Genet. 1997, 17:275-276.
122. Sunahara S., Nakamura K., Nakao K., Gondo Y., Nagata Y., Katsuki M. The oocyte-specific methylated region of the U2afbp-rs/U2af1-rs1 gene is dispensable for its imprinted methylation. Biochem. Biophys. Res. Commun. 2000, 268:590-595.
123. Santos F., Hendrich B., Reik W., Dean W. Dynamic reprogramming of DNA methylation in the early mouse embryo. Dev. Biol. 2002, 241:172-182.
124. Stoger R., Kubicka P., Liu C.G., Kafri T., Razin A., Cedar H., Barlow D.P. Maternal-specific methylation of the imprinted mouse Igf2r locus identifies the expressed locus as carrying the imprinting signal. Cell 1993, 73:61-71.
125. Ariel M., Robinson E., McCarrey J.R., Cedar H. Gamete-specific methylation correlates with imprinting of the murine Xist gene. Nat. Genet. 1995, 9:312-315.
126. Zuccotti M., Monk M. Methylation of the mouse Xist gene in sperm and eggs correlates with imprinted Xist expression and paternal X-inactivation. Nat. Genet. 1995, 9:316-320.
127. Tucker K.L., Beard C., Dausmann J., Jackson-Grusby L., Laird P.W., Lei H., Li E., Jaenisch R. Germ-line passage is required for establishment of methylation and expression patterns of imprinted but not of nonimprinted genes. Genes Dev. 1996, 10:1008-1020.
128. Brandeis M., Frank D., Keshet I., Siegfried Z., Mendelsohn M., Nemes A., Temper V., Razin A., Cedar H. Sp1 elements protect a CpG island from de novo methylation. Nature 1994, 371:435-438.
129. Macleod D., Charlton J., Mullins J., Bird A.P. Sp1 sites in the mouse aprt gene promoter are required to prevent methylation of the CpG island. Genes Dev. 1994, 8:2282-2292.
130. Schoenherr C.J., Levorse J.M., Tilghman S.M. CTCF maintains differential methylation at the Igf2/H19 locus. Nat. Genet. 2003, 33:66-69.
131. Pant V., Mariano P., Kanduri C., Mattsson A., Lobanenkov V., Heuchel R., Ohlsson R. The nucleotides responsible for the direct physical contact between the chromatin insulator protein CTCF and the H19 imprinting control region manifest parent of origin-specific long-distance insulation and methylation-free domains. Genes Dev. 2003, 17:586-590.
132. Fedoriw A.M., Stein P., Svoboda P., Schultz R.M., Bartolomei M.S. Transgenic RNAi reveals essential function for CTCF in H19 gene imprinting. Science 2004, 303:238-240.
133. Li E., Bestor T.H., Jaenisch R. Targeted mutation of the DNA methyltransferase gene results in embryonic lethality. Cell 1992, 69:915-926.
134. Okano M., Bell D.W., Haber D.A., Li E. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 1999, 99:247-257.
135. Chen T., Ueda Y., Dodge J.E., Wang Z., Li E. Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b. Mol. Cell. Biol. 2003, 23:5594-5605.
136. Bourc'his D., Xu G.L., Lin C.S., Bollman B., Bestor T.H. Dnmt3L and the establishment of maternal genomic imprints. Science 2001, 294:2536-2539.
137. Mager J., Montgomery N.D., de Villena F.P., Magnuson T. Genome imprinting regulated by the mouse Polycomb group protein Eed. Nat. Genet. 2003, 33:502-507.
138. Yoder J.A., Walsh C.P., Bestor T.H. Cytosine methylation and the ecology of intragenomic parasites. Trends Genet. 1997, 13:335-340.
139. Fanning T.G., Singer M.F. LINE-1: a mammalian transposable element. Biochim. Biophys. Acta. 1987, 910:203-212.
140. Bailey J.A., Carrel L., Chakravarti A., Eichler E.E. Molecular evidence for a relationship between LINE-1 elements and X chromosome inactivation: the Lyon repeat hypothesis. Proc. Natl. Acad. Sci. U S A 2000, 97:6634-6639.
141. Lengauer C., Kinzler K.W., Vogelstein B. DNA methylation and genetic instability in colorectal cancer cells. Proc. Natl. Acad. Sci. U S A 1997, 94:2545-2550.
142. Evsikov, A. V., de Vries, W. N., Peaston, A. E., Radford, E. E., Fancher, K. S., Chen, F. H., Blake, J. A., Bult, C. J., Latham, K. E., Solter, D., and Knowles, B. B. Systems biology of the two-cell mouse embryo. Cytogenet. Genome Res. 105, 240-250.
143. Knowles B.B., Evsikov A.V., de Vries W.N., Peaston A.E., Solter D. Molecular control of the oocyte to embryo transition. Philos. Trans. R. Soc. Lond. B. Biol. Sci. 2003, 358:1381-1387.
144. Stevenson D.S., Jarvis P. Chromatin silencing: RNA in the driving seat. Curr. Biol. 2003, 13:R13-R15.
145. Baulcombe D.C. Molecular biology: unwinding RNA silencing. Science 2000, 290:1108-1109.
146. Zeng F., Schultz R.M. Gene expression in mouse oocytes and preimplantation embryos: use of suppression subtractive hybridization to identify oocyte- and embryo-specific genes. Biol. Reprod. 2003, 68:31-39.
147. Svoboda P., Stein P., Anger M., Bernstein E., Hannon G.J., Schultz R.M. RNAi and expression of retrotransposons MuERV-L and IAP in preimplantation mouse embryos. Dev. Biol. 2004, 269:276-285.
148. Brockdorff N., Ashworth A., Kay G.F., McCabe V.M., Norris D.P., Cooper P.J., Swift S., Rastan S. The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 1992, 71:515-526.
149. Lee J.T., Davidow L.S., Warshawsky D. Tsix, a gene antisense to Xist at the X-inactivation centre. Nat. Genet. 1999, 21:400-404.
150. Lifschytz E., Lindsley D.L. The role of X-chromosome inactivation during spermatogenesis (Drosophila-allocycly-chromosome evolution-male sterility-dosage compensation). Proc. Natl. Acad. Sci. U S A 1972, 69:182-186.
151. Kratzer P.G., Chapman V.M. X chromosome reactivation in oocytes of Mus caroli. Proc. Natl. Acad. Sci. U S A 1981, 78:3093-3097.
152. McCarrey J.R., Dilworth D.D. Expression of Xist in mouse germ cells correlates with X-chromosome inactivation. Nat. Genet. 1992, 2:200-203.
153. Norris D.P., Patel D., Kay G.F., Penny G.D., Brockdorff N., Sheardown S.A., Rastan S. Evidence that random and imprinted Xist expression is controlled by preemptive methylation. Cell 1994, 77:41-51.
154. Turner J.M., Mahadevaiah S.K., Elliott D.J., Garchon H.J., Pehrson J.R., Jaenisch R., Burgoyne P.S. Meiotic sex chromosome inactivation in male mice with targeted disruptions of Xist. J. Cell. Sci. 2002, 115:4097-4105.
155. McCarrey J.R., Watson C., Atencio J., Ostermeier G.C., Marahrens Y., Jaenisch R., Krawetz S.A. X-chromosome inactivation during spermatogenesis is regulated by an Xist/Tsix-independent mechanism in the mouse. Genesis 2002, 34:257-266.
156. Okamoto I., Otte A.P., Allis C.D., Reinberg D., Heard E. Epigenetic dynamics of imprinted X inactivation during early mouse development. Science 2003, 303:644-649.
157. Hartshorn C., Rice J.E., Wangh L.J. Developmentally-regulated changes of Xist RNA levels in single preimplantation mouse embryos, as revealed by quantitative real-time PCR. Mol. Reprod. Dev. 2002, 61:425-436.
158. Takagi N. Differentiation of X chromosomes in early female mouse embryos. Exp. Cell. Res. 1974, 86:127-135.
159. Sugawara O., Takagi N., Sasaki M. Correlation between X-chromosome inactivation and cell differentiation in female preimplantation mouse embryos. Cytogenet. Cell. Genet. 1985, 39:210-219.
160. Epstein C.J., Smith S., Travis B., Tucker G. Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos. Nature 1978, 274:500-503.
161. Huynh K.D., Lee J.T. Inheritance of a preinactivated paternal X chromosome in early mouse embryos. Nature 2003, 426:857-862.
162. Sheardown S.A., Duthie S.M., Johnston C.M., Newall A.E., Formstone E.J., Arkell R.M., Nesterova T.B., Alghisi G.C., Rastan S., Brockdorff N. Stabilization of Xist RNA mediates initiation of X chromosome inactivation. Cell 1997, 91:99-107.
163. Panning B., Dausman J., Jaenisch R. X chromosome inactivation is mediated by Xist RNA stabilization. Cell 1997, 90:907-916.
164. Sado T., Wang Z., Sasaki H., Li E. Regulation of imprinted X-chromosome inactivation in mice by Tsix. Development 2001, 128:1275-1286.
165. Eggan K., Akutsu H., Hochedlinger K., Rideout W., Yanagimachi R., Jaenisch R. X-chromosome inactivation in cloned mouse embryos. Science 2000, 290:1578-1581.
166. Penny G.D., Kay G.F., Sheardown S.A., Rastan S., Brockdorff N. Requirement for Xist in X chromosome inactivation. Nature 1996, 379:131-137.
167. Marahrens Y., Panning B., Dausman J., Strauss W., Jaenisch R. Xist-deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev. 1997, 11:156-166.
168. Lee J.T., Lu N. Targeted mutagenesis of Tsix leads to nonrandom X inactivation. Cell 1999, 99:47-57.
169. Lee J.T. Disruption of imprinted X inactivation by parent-of-origin effects at Tsix. Cell 2000, 103:17-27.
170. Ganesan S., Silver D.P., Greenberg R.A., Avni D., Drapkin R., Miron A., Mok S.C., Randrianarison V., Brodie S., Salstrom J., Rasmussen T.P., Klimke A., Marrese C., Marahrens Y., Deng C.X., Feunteun J., Livingston D.M. BRCA1 supports XIST RNA concentration on the inactive X chromosome. Cell 2002, 111:393-405.
171. Sado T., Fenner M.H., Tan S.S., Tam P., Shioda T., Li E. X inactivation in the mouse embryo deficient for Dnmt1: distinct effect of hypomethylation on imprinted and random X inactivation. Dev. Biol. 2000, 225:294-303.
172. Wang J., Mager J., Chen Y., Schneider E., Cross J.C., Nagy A., Magnuson T. Imprinted X inactivation maintained by a mouse Polycomb group gene. Nat. Genet. 2001, 28:371-375.
173. O'Carroll, D., Erhardt, S., Pagani, M., Barton, S. C., Surani, M. A., and Jenuwein, T. The polycomb-group gene Ezh2 is required for early mouse development. Mol. Cell. Biol. 21, 4330-4336.
174. Bachvarova R., De Leon V. Polyadenylated RNA of mouse ova and loss of maternal RNA in early development. Dev. Biol. 1980, 74:1-8.
175. Clegg K.B., Piko L. Poly(A) length, cytoplasmic adenylation and synthesis of poly(A)+ RNA in early mouse embryos. Dev. Biol. 1983, 95:331-341.
176. Paynton B.V., Rempel R., Bachvarova R. Changes in state of adenylation and time course of degradation of maternal mRNAs during oocyte maturation and early embryonic development in the mouse. Dev. Biol. 1988, 129:304-314.
177. Perlick H.A., Medghalchi S.M., Spencer F.A., Kendzior R.J., Dietz H.C. Mammalian orthologues of a yeast regulator of nonsense transcript stability. Proc. Natl. Acad. Sci. U S A 1996, 93:10928-10932.
178. Medghalchi S.M., Frischmeyer P.A., Mendell J.T., Kelly A.G., Lawler A.M., Dietz H.C. Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum. Mol. Genet. 2001, 10:99-105.
179. Bernstein E., Kim S.Y., Carmell M.A., Murchison E.P., Alcorn H., Li M.Z., Mills A.A., Elledge S.J., Anderson K.V., Hannon G.J. Dicer is essential for mouse development. Nat. Genet. 2003, 35:215-217.
180. Cerritelli S.M., Frolova E.G., Feng C., Grinberg A., Love P.E., Crouch R.J. Failure to produce mitochondrial DNA results in embryonic lethality in Rnaseh1 null mice. Mol. Cell. 2003, 11:807-815.
181. Gu W., Tekur S., Reinbold R., Eppig J.J., Choi Y.C., Zheng J.Z., Murray M.T., Hecht N.B. Mammalian male and female germ cells express a germ cell-specific Y-Box protein, MSY2. Biol. Reprod. 1998, 59:1266-1274.
182. Yu J., Hecht N.B., Schultz R.M. RNA-binding properties and translation repression in vitro by germ cell-specific MSY2 protein. Biol. Reprod. 2002, 67:1093-1098.
183. Bashirullah A., Halsell S.R., Cooperstock R.L., Kloc M., Karaiskakis A., Fisher W.W., Fu W., Hamilton J.K., Etkin L.D., Lipshitz H.D. Joint action of two RNA degradation pathways controls the timing of maternal transcript elimination at the midblastula transition in Drosophila melanogaster. EMBO J. 1999, 18:2610-2620.
184. Tadros W., Houston S.A., Bashirullah A., Cooperstock R.L., Semotok J.L., Reed B.H., Lipshitz H.D. Regulation of maternal transcript destabilization during egg activation in Drosophila. Genetics 2003, 164:989-1001.
185. Ledan E., Polanski Z., Terret M.E., Maro B. Meiotic maturation of the mouse oocyte requires an equilibrium between cyclin B synthesis and degradation. Dev. Biol. 2001, 232:400-413.
186. Suzumori N., Burns K.H., Yan W., Matzuk M.M. RFPL4 interacts with oocyte proteins of the ubiquitin-proteasome degradation pathway. Proc. Natl. Acad. Sci. U S A 2003, 100:550-555.
187. Rajkovic A., Lee J.H., Yan C., Matzuk M.M. The ret finger protein-like 4 gene, Rfpl4, encodes a putative E3 ubiquitin-protein ligase expressed in adult germ cells. Mech. Dev. 2002, 112:173-177.
188. Ruland J., Sirard C., Elia A., MacPherson D., Wakeham A., Li L., de la Pompa J.L., Cohen S.N., Mak T.W. p53 accumulation, defective cell proliferation, and early embryonic lethality in mice lacking tsg101. Proc. Natl. Acad. Sci. U S A 2001, 98:1859-1864.
189. Wang Y., Penfold S., Tang X., Hattori N., Riley P., Harper J.W., Cross J.C., Tyers M. Deletion of the Cul1 gene in mice causes arrest in early embryogenesis and accumulation of cyclin E. Curr. Biol. 1999, 9:1191-1194.
190. Dealy M.J., Nguyen K.V., Lo J., Gstaiger M., Krek W., Elson D., Arbeit J., Kipreos E.T., Johnson R.S. Loss of Cul1 results in early embryonic lethality and dysregulation of cyclin E. Nat. Genet. 1999, 23:245-248.
191. Singer J.D., Gurian-West M., Clurman B., Roberts J.M. Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev. 1999, 13:2375-2387.
192. Li B., Ruiz J.C., Chun K.T. CUL-4A is critical for early embryonic development. Mol. Cell. Biol. 2002, 22:4997-5005.
193. Sakao Y., Kawai T., Takeuchi O., Copeland N.G., Gilbert D.J., Jenkins N.A., Takeda K., Akira S. Mouse proteasomal ATPases Psmc3 and Psmc4: genomic organization and gene targeting. Genomics 2000, 67:1-7.
194. Pantaleon M., Kanai-Azuma M., Mattick J.S., Kaibuchi K., Kaye P.L., Wood S.A. FAM deubiquitylating enzyme is essential for preimplantation mouse embryo development. Mech. Dev. 2001, 109:151-160.
195. Lykke-Andersen K., Schaefer L., Menon S., Deng X.W., Miller J.B., Wei N. Disruption of the COP9 signalosome Csn2 subunit in mice causes deficient cell proliferation, accumulation of p53 and cyclin E, and early embryonic death. Mol. Cell. Biol. 2003, 23:6790-6797.
196. Yan J., Walz K., Nakamura H., Carattini-Rivera S., Zhao Q., Vogel H., Wei N., Justice M.J., Bradley A., Lupski J.R. COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol. Cell. Biol. 2003, 23:6798-6808.
197. Hochstrasser M. Evolution and function of ubiquitin-like protein-conjugation systems. Nat. Cell. Biol. 2000, 2:E153-E157.
198. Tateishi K., Omata M., Tanaka K., Chiba T. The NEDD8 system is essential for cell cycle progression and morphogenetic pathway in mice. J. Cell. Biol. 2001, 155:571-579.
199. Sutovsky P., Moreno R.D., Ramalho-Santos J., Dominko T., Simerly C., Schatten G. Ubiquitin tag for sperm mitochondria. Nature 1999, 402:371-372.
200. Sutovsky P., Van Leyen K., McCauley T., Day B.N., Sutovsky M. Degradation of paternal mitochondria after fertilization: implications for heteroplasmy, assisted reproductive technologies and mtDNA inheritance. Reprod. Biomed. Online. 2004, 8:24-33.
201. Brenner C.A., Barritt J.A., Willadsen S., Cohen J. Mitochondrial DNA heteroplasmy after human ooplasmic transplantation. Fertil. Steril. 2000, 74:573-578.
202. Sutovsky P., Motlik J., Neuber E., Pavlok A., Schatten G., Palecek J., Hyttel P., Adebayo O.T., Adwan K., Alberio R., Bagis H., Bataineh Z., Bjerregaard B., Bodo S., Bryja V., Carrington M., Couf M., de la Fuente R., Diblik J., Esner M., Forejt J., Fulka J., Geussova G., Gjorret J.O., Libik M., Hampl A., Hassane M.S., Houshmand M., Hozak P., Jezova M., Kania G., Kanka J., Kandil O.M., Kishimoto T., Klima J., Kohoutek J., Kopska T., Kubelka M., Lapathitis G., Laurincik J., Lefevre B., Mihalik J., Novakova M., Oko R., Omelka R., Owiny D., Pachernik J., Pacholikova J., Peknicova J., Pesty A., Ponya Z., Preclikova H., Sloskova A., Svoboda P., Strejcek F., Toth S., Tepla O., Valdivia M., Vodicka P., Zudova D. Accumulation of the proteolytic marker peptide ubiquitin in the trophoblast of mammalian blastocysts. Cloning Stem Cells 2001, 3:157-161.
203. Tilly J.L. Commuting the death sentence: how oocytes strive to survive. Nat. Rev. Mol. Cell. Biol. 2001, 2:838-848.
204. Kamjoo M., Brison D.R., Kimber S.J. Apoptosis in the preimplantation mouse embryo: effect of strain difference and in vitro culture. Mol. Reprod. Dev. 2002, 61:67-77.
205. Threadgill D.W., Dlugosz A.A., Hansen L.A., Tennenbaum T., Lichti U., Yee D., LaMantia C., Mourton T., Herrup K., Harris R.C., et al. Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 1995, 269:230-234.
206. Kelkar R.L., Dharma S.J., Nandedkar T.D. Expression of Fas and Fas ligand protein and mRNA in mouse oocytes and embryos. Reproduction 2003, 126:791-799.
207. Zou G.M., Reznikoff-Etievant M.F., Leon A., Verge V., Hirsch F., Milliez J. Fas-mediated apoptosis of mouse embryo stem cells: its role during embryonic development. Am. J. Reprod. Immunol. 2000, 43:240-248.
208. Yeh W.C., Pompa J.L., McCurrach M.E., Shu H.B., Elia A.J., Shahinian A., Ng M., Wakeham A., Khoo W., Mitchell K., El-Deiry W.S., Lowe S.W., Goeddel D.V., Mak T.W. FADD: essential for embryo development and signaling from some, but not all, inducers of apoptosis. Science 1998, 279:1954-1958.
209. Yeh W.C., Itie A., Elia A.J., Ng M., Shu H.B., Wakeham A., Mirtsos C., Suzuki N., Bonnard M., Goeddel D.V., Mak T.W. Requirement for Casper (c-FLIP) in regulation of death receptor-induced apoptosis and embryonic development. Immunity 2000, 12:633-642.
210. Michaelson J.S., Bader D., Kuo F., Kozak C., Leder P. Loss of Daxx, a promiscuously interacting protein, results in extensive apoptosis in early mouse development. Genes Dev. 1999, 13:1918-1923.
211. Exley G.E., Tang C., McElhinny A.S., Warner C.M. Expression of caspase and BCL-2 apoptotic family members in mouse preimplantation embryos. Biol. Reprod. 1999, 61:231-239.
212. Burns K.H., Matzuk M.M. The application of gene ablation and related technologies to the study of ovarian physiology. The Ovary 2004, Academic Press, Plainview, NY. P.C.K. Leung, E.Y. Adashi (Eds.).
213. Szegezdi E., Fitzgerald U., Samali A. Caspase-12 and ER-stress-mediated apoptosis: the story so far. Ann. N Y Acad. Sci. 2003, 1010:186-194.
214. Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai J., Tanikawa H., Shimizu Y., Tanaka T. Survivin acts as an antiapoptotic factor during the development of mouse preimplantation embryos. Dev. Biol. 2003, 256:331-341.
215. Uren A.G., Wong L., Pakusch M., Fowler K.J., Burrows F.J., Vaux D.L., Choo K.H. Survivin and the inner centromere protein INCENP show similar cell-cycle localization and gene knockout phenotype. Curr. Biol. 2000, 10:1319-1328.
216. Conway E.M., Pollefeyt S., Steiner-Mosonyi M., Luo W., Devriese A., Lupu F., Bono F., Leducq N., Dol F., Schaeffer P., Collen D., Herbert J.M. Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways. Gastroenterology 2002, 123:619-631.
217. Kubiak J.Z., Ciemerych M.A. Cell cycle regulation in early mouse embryos. Novartis Found. Symp. 2001, 237:79-89. discussion 89-99.
218. Deng M.Q., Shen S.S. A specific inhibitor of p34(cdc2)/cyclin B suppresses fertilization-induced calcium oscillations in mouse eggs. Biol. Reprod. 2000, 62:873-878.
219. Kono T., Jones K.T., Bos-Mikich A., Whittingham D.G., Carroll J. A cell cycle-associated change in Ca2+ releasing activity leads to the generation of Ca2+ transients in mouse embryos during the first mitotic division. J. Cell. Biol. 1996, 132:915-923.
220. Pahlavan G., Polanski Z., Kalab P., Golsteyn R., Nigg E.A., Maro B. Characterization of polo-like kinase 1 during meiotic maturation of the mouse oocyte. Dev. Biol. 2000, 220:392-400.
221. Tong C., Fan H.Y., Lian L., Li S.W., Chen D.Y., Schatten H., Sun Q.Y. Polo-like kinase-1 is a pivotal regulator of microtubule assembly during mouse oocyte meiotic maturation, fertilization, and early embryonic mitosis. Biol. Reprod. 2002, 67:546-554.
222. Zernicka-Goetz M., Ciemerych M.A., Kubiak J.Z., Tarkowski A.K., Maro B. Cytostatic factor inactivation is induced by a calcium-dependent mechanism present until the second cell cycle in fertilized but not in parthenogenetically activated mouse eggs. J. Cell. Sci. 1995, 108:469-474. (Pt 2).
223. Winston N., Bourgain-Guglielmetti F., Ciemerych M.A., Kubiak J.Z., Senamaud-Beaufort C., Carrington M., Brechot C., Sobczak-Thepot J. Early development of mouse embryos null mutant for the cyclin A2 gene occurs in the absence of maternally derived cyclin A2 gene products. Dev. Biol. 2000, 223:139-153.
224. den Elzen N., Pines J. Cyclin A is destroyed in prometaphase and can delay chromosome alignment and anaphase. J. Cell. Biol. 2001, 153:121-136.
225. Ciemerych M.A., Maro B., Kubiak J.Z. Control of duration of the first two mitoses in a mouse embryo. Zygote 1999, 7:293-300.
226. Moore G.D., Ayabe T., Kopf G.S., Schultz R.M. Temporal patterns of gene expression of G1-S cyclins and cdks during the first and second mitotic cell cycles in mouse embryos. Mol. Reprod. Dev. 1996, 45:264-275.
227. Iwamori N., Naito K., Sugiura K., Tojo H. Preimplantation-embryo-specific cell cycle regulation is attributed to the low expression level of retinoblastoma protein. FEBS Lett. 2002, 526:119-123.
228. Day M.L., Pickering S.J., Johnson M.H., Cook D.I. Cell-cycle control of a large-conductance K+ channel in mouse early embryos. Nature 1993, 365:560-562.
229. Day M.L., Winston N., McConnell J.L., Cook D., Johnson M.H. tiK+ toK+: an embryonic clock?. Reprod. Fertil. Dev. 2001, 13:69-79.
230. Day M.L., Johnson M.H., Cook D.I. A cytoplasmic cell cycle controls the activity of a K+ channel in preimplantation mouse embryos. EMBO J. 1998, 17:1952-1960.
231. Hunt P.A., Hassold T.J. Sex matters in meiosis. Science 2002, 296:2181-2183.
232. Liu L., Trimarchi J.R., Smith P.J., Keefe D.L. Checkpoint for DNA integrity at the first mitosis after oocyte activation. Mol. Reprod. Dev. 2002, 62:277-288.
233. Fulka J., First N.L., Fulka J., Moor R.M. Checkpoint control of the G2/M phase transition during the first mitotic cycle in mammalian eggs. Hum. Reprod. 1999, 14:1582-1587.
234. Shimura T., Inoue M., Taga M., Shiraishi K., Uematsu N., Takei N., Yuan Z.M., Shinohara T., Niwa O. p53-dependent S-phase damage checkpoint and pronuclear cross talk in mouse zygotes with X-irradiated sperm. Mol. Cell. Biol. 2002, 22:2220-2228.
235. Shimura T., Toyoshima M., Taga M., Shiraishi K., Uematsu N., Inoue M., Niwa O. The novel surveillance mechanism of the Trp53-dependent s-phase checkpoint ensures chromosome damage repair and preimplantation-stage development of mouse embryos fertilized with x-irradiated sperm. Radiat. Res. 2002, 158:735-742.
236. Brandriff B., Pedersen R.A. Repair of the ultraviolet-irradiated male genome in fertilized mouse eggs. Science 1981, 211:1431-1433.
237. Matsuda Y., Seki N., Utsugi-Takeuchi T., Tobari I. X-ray- and mitomycin C (MMC)-induced chromosome aberrations in spermiogenic germ cells and the repair capacity of mouse eggs for the X-ray and MMC damage. Mutat. Res. 1989, 211:65-75.
238. Matsuda Y., Tobari I. Repair capacity of fertilized mouse eggs for X-ray damage induced in sperm and mature oocytes. Mutat. Res. 1989, 210:35-47.
239. Murphy M., Stinnakre M.G., Senamaud-Beaufort C., Winston N.J., Sweeney C., Kubelka M., Carrington M., Brechot C., Sobczak-Thepot J. Delayed early embryonic lethality following disruption of the murine cyclin A2 gene. Nat. Genet. 1997, 15:83-86.
240. Liu D., Matzuk M.M., Sung W.K., Guo Q., Wang P., Wolgemuth D.J. Cyclin A1 is required for meiosis in the male mouse. Nat. Genet. 1998, 20:377-380.
241. Brandeis M., Rosewell I., Carrington M., Crompton T., Jacobs M.A., Kirk J., Gannon J., Hunt T. Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero. Proc. Natl. Acad. Sci. U S A 1998, 95:4344-4349.
242. Geng Y., Yu Q., Sicinska E., Das M., Schneider J.E., Bhattacharya S., Rideout W.M., Bronson R.T., Gardner H., Sicinski P. Cyclin E ablation in the mouse. Cell 2003, 114:431-443.
243. Parisi T., Beck A.R., Rougier N., McNeil T., Lucian L., Werb Z., Amati B. Cyclins E1 and E2 are required for endoreplication in placental trophoblast giant cells. EMBO J. 2003, 22:4794-4803.
244. Ciemerych M.A., Kenney A.M., Sicinska E., Kalaszczynska I., Bronson R.T., Rowitch D.H., Gardner H., Sicinski P. Development of mice expressing a single D-type cyclin. Genes Dev. 2002, 16:3277-3289.
245. Lei M., Tye B.K. Initiating DNA synthesis: from recruiting to activating the MCM complex. J. Cell. Sci. 2001, 114:1447-1454.
246. Kim J.M., Nakao K., Nakamura K., Saito I., Katsuki M., Arai K., Masai H. Inactivation of Cdc7 kinase in mouse ES cells results in S-phase arrest and p53-dependent cell death. EMBO J. 2002, 21:2168-2179.
247. Yoshida K., Kuo F., George E.L., Sharpe A.H., Dutta A. Requirement of CDC45 for postimplantation mouse development. Mol. Cell. Biol. 2001, 21:4598-4603.
248. Liu Q., Guntuku S., Cui X.S., Matsuoka S., Cortez D., Tamai K., Luo G., Carattini-Rivera S., DeMayo F., Bradley A., Donehower L.A., Elledge S.J. Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint. Genes Dev. 2000, 14:1448-1459.
249. Hirao A., Cheung A., Duncan G., Girard P.M., Elia A.J., Wakeham A., Okada H., Sarkissian T., Wong J.A., Sakai T., De Stanchina E., Bristow R.G., Suda T., Lowe S.W., Jeggo P.A., Elledge S.J., Mak T.W. Chk2 is a tumor suppressor that regulates apoptosis in both an ataxia telangiectasia mutated (ATM)-dependent and an ATM-independent manner. Mol. Cell. Biol. 2002, 22:6521-6532.
250. Lincoln A.J., Wickramasinghe D., Stein P., Schultz R.M., Palko M.E., De Miguel M.P., Tessarollo L., Donovan P.J. Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation. Nat. Genet. 2002, 30:446-449.
251. Wickramasinghe D., Becker S., Ernst M.K., Resnick J.L., Centanni J.M., Tessarollo L., Grabel L.B., Donovan P.J. Two CDC25 homologues are differentially expressed during mouse development. Development 1995, 121:2047-2056.
252. Putkey F.R., Cramer T., Morphew M.K., Silk A.D., Johnson R.S., McIntosh J.R., Cleveland D.W. Unstable kinetochore-microtubule capture and chromosomal instability following deletion of CENP-E. Dev. Cell. 2002, 3:351-365.
253. Warner P., Wiley L.M., Oudiz D.J., Overstreet J.W., Raabe O.G. Paternally inherited effects of gamma radiation on mouse preimplantation development detected by the chimera assay. Radiat. Res. 1991, 128:48-58.
254. Obasaju M.F., Wiley L.M., Oudiz D.J., Raabe O., Overstreet J.W. A chimera embryo assay reveals a decrease in embryonic cellular proliferation induced by sperm from X-irradiated male mice. Radiat. Res. 1989, 118:246-256.
255. Rassoulzadegan M., Yang Y., Cuzin F. APLP2, a member of the Alzheimer precursor protein family, is required for correct genomic segregation in dividing mouse cells. EMBO J. 1998, 17:4647-4656.
256. Brown E.J., Baltimore D. ATR disruption leads to chromosomal fragmentation and early embryonic lethality. Genes Dev. 2000, 14:397-402.
257. de Klein A., Muijtjens M., van Os R., Verhoeven Y., Smit B., Carr A.M., Lehmann A.R., Hoeijmakers J.H. Targeted disruption of the cell-cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr. Biol. 2000, 10:479-482.
258. Kalitsis P., Earle E., Fowler K.J., Choo K.H. Bub3 gene disruption in mice reveals essential mitotic spindle checkpoint function during early embryogenesis. Genes Dev. 2000, 14:2277-2282.
259. Howman E.V., Fowler K.J., Newson A.J., Redward S., MacDonald A.C., Kalitsis P., Choo K.H. Early disruption of centromeric chromatin organization in centromere protein A (Cenpa) null mice. Proc. Natl. Acad. Sci. U S A 2000, 97:1148-1153.
260. Kalitsis P., Fowler K.J., Earle E., Hill J., Choo K.H. Targeted disruption of mouse centromere protein C gene leads to mitotic disarray and early embryo death. Proc. Natl. Acad. Sci. U S A 1998, 95:1136-1141.
261. Dodge J.E., Kang Y.K., Beppu H., Lei H., Li E. Histone H3-K9 methyltransferase ESET is essential for early development. Mol. Cell. Biol. 2004, 24:2478-2486.
262. Larsen E., Gran C., Saether B.E., Seeberg E., Klungland A. Proliferation failure and gamma radiation sensitivity of Fen1 null mutant mice at the blastocyst stage. Mol. Cell. Biol. 2003, 23:5346-5353.
263. Cutts S.M., Fowler K.J., Kile B.T., Hii L.L., O'Dowd R.A., Hudson D.F., Saffery R., Kalitsis P., Earle E., Choo K.H. Defective chromosome segregation, microtubule bundling and nuclear bridging in inner centromere protein gene (Incenp)-disrupted mice. Hum. Mol. Genet. 1999, 8:1145-1155.
264. Dumon-Jones V., Frappart P.O., Tong W.M., Sajithlal G., Hulla W., Schmid G., Herceg Z., Digweed M., Wang Z.Q. Nbn heterozygosity renders mice susceptible to tumor formation and ionizing radiation-induced tumorigenesis. Cancer Res. 2003, 63:7263-7269.
265. Tsuzuki T., Fujii Y., Sakumi K., Tominaga Y., Nakao K., Sekiguchi M., Matsushiro A., Yoshimura Y., Morita T. Targeted disruption of the Rad51 gene leads to lethality in embryonic mice. Proc. Natl. Acad. Sci. U S A 1996, 93:6236-6240.
266. Bemark M., Khamlichi A.A., Davies S.L., Neuberger M.S. Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro. Curr. Biol. 2000, 10:1213-1216.
267. Wittschieben J., Shivji M.K., Lalani E., Jacobs M.A., Marini F., Gearhart P.J., Rosewell I., Stamp G., Wood R.D. Disruption of the developmentally regulated Rev3l gene causes embryonic lethality. Curr. Biol. 2000, 10:1217-1220.
268. Kajiwara K., J O.W., Sakurai T., Yamashita S., Tanaka M., Sato M., Tagawa M., Sugaya E., Nakamura K., Nakao K., Katsuki M., Kimura M. Sez4 gene encoding an elongation subunit of DNA polymerase zeta is required for normal embryogenesis. Genes Cells 2001, 6:99-106.
269. Van Sloun P.P., Varlet I., Sonneveld E., Boei J.J., Romeijn R.J., Eeken J.C., De Wind N. Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage. Mol. Cell. Biol. 2002, 22:2159-2169.
270. Cao S., Bendall H., Hicks G.G., Nashabi A., Sakano H., Shinkai Y., Gariglio M., Oltz E.M., Ruley H.E. The high-mobility-group box protein SSRP1/T160 is essential for cell viability in day 3.5 mouse embryos. Mol. Cell. Biol. 2003, 23:5301-5307.
271. Bultman S., Gebuhr T., Yee D., La Mantia C., Nicholson J., Gilliam A., Randazzo F., Metzger D., Chambon P., Crabtree G., Magnuson T. A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes. Mol. Cell. 2000, 6:1287-1295.
272. Stopka T., Skoultchi A.I. The ISWI ATPase Snf2h is required for early mouse development. Proc. Natl. Acad. Sci. U S A 2003, 100:14097-14102.
273. Klochendler-Yeivin A., Fiette L., Barra J., Muchardt C., Babinet C., Yaniv M. The murine SNF5/INI1 chromatin remodeling factor is essential for embryonic development and tumor suppression. EMBO Rep. 2000, 1:500-506.
274. Karlseder J., Kachatrian L., Takai H., Mercer K., Hingorani S., Jacks T., de Lange T. Targeted deletion reveals an essential function for the telomere length regulator Trf1. Mol. Cell. Biol. 2003, 23:6533-6541.
275. Morham S.G., Kluckman K.D., Voulomanos N., Smithies O. Targeted disruption of the mouse topoisomerase I gene by camptothecin selection. Mol. Cell. Biol. 1996, 16:6804-6809.
276. Akimitsu N., Adachi N., Hirai H., Hossain M.S., Hamamoto H., Kobayashi M., Aratani Y., Koyama H., Sekimizu K. Enforced cytokinesis without complete nuclear division in embryonic cells depleting the activity of DNA topoisomerase IIalpha. Genes Cells 2003, 8:393-402.
277. Sakkas D., Trounson A.O., Kola I. In vivo cleavage rates and viability obtained for early cleavage mouse embryos in co-culture with oviduct cells. Reprod. Fertil. Dev. 1989, 1:127-136.
278. Sakkas D., Trounson A.O. Co-culture of mouse embryos with oviduct and uterine cells prepared from mice at different days of pseudopregnancy. J. Reprod. Fertil. 1990, 90:109-118.
279. Yeung W.S., Ho P.C., Lau E.Y., Chan S.T. Improved development of human embryos in vitro by a human oviductal cell co-culture system. Hum. Reprod. 1992, 7:1144-1149.
280. Yeung W.S., Lau E.Y., Chan S.T., Ho P.C. Coculture with homologous oviductal cells improved the implantation of human embryos: a prospective randomized control trial. J. Assist. Reprod. Genet. 1996, 13:762-767.
281. Liu L.P., Chan S.T., Ho P.C., Yeung W.S. Human oviductal cells produce high molecular weight factor(s) that improves the development of mouse embryo. Hum. Reprod. 1995, 10:2781-2786.
282. Lee K.F., Chow J.F., Xu J.S., Chan S.T., Ip S.M., Yeung W.S. A comparative study of gene expression in murine embryos developed in vivo, cultured in vitro, and cocultured with human oviductal cells using messenger ribonucleic acid differential display. Biol. Reprod. 2001, 64:910-917.
283. Lee Y.L., Lee K.F., Xu J.S., He Q.Y., Chiu J.F., Lee W.M., Luk J.M., Yeung W.S. The embryotrophic activity of oviductal cell-derived complement C3b and iC3b, a novel function of complement protein in reproduction. J. Biol. Chem. 2004, 279:12763-12768.
284. Buhi W.C., Alvarez I.M., Kouba A.J. Secreted proteins of the oviduct. Cells Tiss. Organs 2000, 166:165-179.
285. Ota Y., Shimoya K., Zhang Q., Moriyama A., Chin R., Tenma K., Kimura T., Koyama M., Azuma C., Murata Y. The expression of secretory leukocyte protease inhibitor (SLPI) in the fallopian tube: SLPI protects the acrosome reaction of sperm from inhibitory effects of elastase. Hum. Reprod. 2002, 17:2517-2522.
286. Butzow R. The human fallopian tube contains placental protein 5. Hum. Reprod. 1989, 4:17-20.
287. Parr M.B., Parr E.L. Immunohistochemical localization of immunoglobulins A, G and M in the mouse female genital tract. J. Reprod. Fertil. 1985, 74:361-370.
288. Araki Y., Nohara M., Yoshida-Komiya H., Kuramochi T., Ito M., Hoshi H., Shinkai Y., Sendai Y. Effect of a null mutation of the oviduct-specific glycoprotein gene on mouse fertilization. Biochem. J. 2003, 374:551-557.
289. Lee K.F., Yao Y.Q., Kwok K.L., Xu J.S., Yeung W.S. Early developing embryos affect the gene expression patterns in the mouse oviduct. Biochem. Biophys. Res. Commun. 2002, 292:564-570.
290. Matzuk M.M., Burns K.H., Viveiros M.M., Eppig J.J. Intercellular communication in the mammalian ovary: oocytes carry the conversation. Science 2002, 296:2178-2180.
291. Paria B.C., Reese J., Das S.K., Dey S.K. Deciphering the cross-talk of implantation: advances and challenges. Science 2002, 296:2185-2188.
292. Salahuddin S., Ookutsu S., Goto K., Nakanishi Y., Nagata Y. Effects of embryo density and co-culture of unfertilized oocytes on embryonic development of in-vitro fertilized mouse embryos. Hum. Reprod. 1995, 10:2382-2385.
293. Hiroi H., Momeda M., Inoue S., Tsuchiya F., Matsumi H., Tsutsumi O., Muramatsu M., Taketani Y. Stage-specific expression of estrogen receptor subtypes and estrogen responsive finger protein in preimplantational mouse embryos. Endocr. J. 1999, 46:153-158.
294. Stromstedt M., Keeney D.S., Waterman M.R., Paria B.C., Conley A.J., Dey S.K. Preimplantation mouse blastocysts fail to express CYP genes required for estrogen biosynthesis. Mol. Reprod. Dev. 1996, 43:428-436.
295. Wang J., Rout U.K., Bagchi I.C., Armant D.R. Expression of calcitonin receptors in mouse preimplantation embryos and their function in the regulation of blastocyst differentiation by calcitonin. Development 1998, 125:4293-4302.
296. Paria B.C., Wang H., Dey S.K. Endocannabinoid signaling in synchronizing embryo development and uterine receptivity for implantation. Chem. Phys. Lipids. 2002, 121:201-210.
297. Bhatnagar P., Papaioannou V.E., Biggers J.D. CSF-1 and mouse preimplantation development in vitro. Development 1995, 121:1333-1339.
298. Dardik A., Schultz R.M. Blastocoel expansion in the preimplantation mouse embryo: stimulatory effect of TGF-alpha and EGF. Development 1991, 113:919-930.
299. Dardik A., Smith R.M., Schultz R.M. Colocalization of transforming growth factor-alpha and a functional epidermal growth factor receptor (EGFR) to the inner cell mass and preferential localization of the EGFR on the basolateral surface of the trophectoderm in the mouse blastocyst. Dev. Biol. 1992, 154:396-409.
300. Tsark E.C., Adamson E.D., Withers G.E., Wiley L.M. Expression and function of amphiregulin during murine preimplantation development. Mol. Reprod. Dev. 1997, 47:271-283.
301. Paria B.C., Das S.K., Andrews G.K., Dey S.K. Expression of the epidermal growth factor receptor gene is regulated in mouse blastocysts during delayed implantation. Proc. Natl. Acad. Sci. USA 1993, 90:55-59.
302. Rappolee D.A., Basilico C., Patel Y., Werb Z. Expression and function of FGF-4 in peri-implantation development in mouse embryos. Development 1994, 120:2259-2269.
303. Feldman B., Poueymirou W., Papaioannou V.E., DeChiara T.M., Goldfarb M. Requirement of FGF-4 for postimplantation mouse development. Science 1995, 267:246-249.
304. Arman E., Haffner-Krausz R., Chen Y., Heath J.K., Lonai P. Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development. Proc. Natl. Acad. Sci. USA 1998, 95:5082-5087.
305. Chai N., Patel Y., Jacobson K., McMahon J., McMahon A., Rappolee D.A. FGF is an essential regulator of the fifth cell division in preimplantation mouse embryos. Dev. Biol. 1998, 198:105-115.
306. Wang Q.T., Piotrowska K., Ciemerych M.A., Milenkovic L., Scott M.P., Davis R.W., Zernicka-Goetz M. A genome-wide study of gene activity reveals developmental signaling pathways in the preimplantation mouse embryo. Dev. Cell. 2004, 6:133-144.
307. Patsoula E., Loutradis D., Drakakis P., Michalas L., Bletsa R., Michalas S. Messenger RNA expression for the follicle-stimulating hormone receptor and luteinizing hormone receptor in human oocytes and preimplantation-stage embryos. Fertil. Steril. 2003, 79:1187-1193.
308. Patsoula E., Loutradis D., Drakakis P., Kallianidis K., Bletsa R., Michalas S. Expression of mRNA for the LH and FSH receptors in mouse oocytes and preimplantation embryos. Reproduction 2001, 121:455-461.
309. Casan E.M., Raga F., Polan M.L. GnRH mRNA and protein expression in human preimplantation embryos. Mol. Hum. Reprod. 1999, 5:234-239.
310. Casan E.M., Raga F., Bonilla-Musoles F., Polan M.L. Human oviductal gonadotropin-releasing hormone: possible implications in fertilization, early embryonic development, and implantation. J. Clin. Endocrinol. Metab. 2000, 85:1377-1381.
311. Raga F., Casan E.M., Kruessel J., Wen Y., Bonilla-Musoles F., Polan M.L. The role of gonadotropin-releasing hormone in murine preimplantation embryonic development. Endocrinology 1999, 140:3705-3712.
312. Pantaleon M., Whiteside E.J., Harvey M.B., Barnard R.T., Waters M.J., Kaye P.L. Functional growth hormone (GH) receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis?. Proc. Natl. Acad. Sci. USA 1997, 94:5125-5130.
313. Fukaya T., Yamanaka T., Terada Y., Murakami T., Yajima A. Growth hormone improves mouse embryo development in vitro, and the effect is neutralized by growth hormone receptor antibody. Tohoku J. Exp. Med. 1998, 184:113-122.
314. Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai J., Tanikawa H., Nakamura A., Honda Y., Sato T., Tanaka T. Ghrelin inhibits the development of mouse preimplantation embryos in vitro. Endocrinology 2003, 144:2623-2633.
315. Kaye P.L. Preimplantation growth factor physiology. Rev. Reprod. 1997, 2:121-127.
316. Doherty A.S., Temeles G.L., Schultz R.M. Temporal pattern of IGF-I expression during mouse preimplantation embryogenesis. Mol. Reprod. Dev. 1994, 37:21-26.
317. Rappolee D.A., Sturm K.S., Behrendtsen O., Schultz G.A., Pedersen R.A., Werb Z. Insulin-like growth factor II acts through an endogenous growth pathway regulated by imprinting in early mouse embryos. Genes Dev. 1992, 6:939-952.
318. Truchet S., Wietzerbin J., Debey P. Mouse oocytes and preimplantation embryos bear the two subunits of interferon-gamma receptor. Mol. Reprod. Dev. 2001, 60:319-330.
319. Mitsunari M., Harada T., Tanikawa M., Iwabe T., Taniguchi F., Terakawa N. The potential role of stem cell factor and its receptor c-kit in the mouse blastocyst implantation. Mol. Hum. Reprod. 1999, 5:874-879.
320. Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai J., Tanikawa H., Murata M., Tanaka T. The role of leptin during the development of mouse preimplantation embryos. Mol. Cell. Endocrinol. 2003, 202:185-189.
321. Kawamura K., Sato N., Fukuda J., Kodama H., Kumagai J., Tanikawa H., Nakamura A., Tanaka T. Leptin promotes the development of mouse preimplantation embryos in vitro. Endocrinology 2002, 143:1922-1931.
322. Nichols J., Davidson D., Taga T., Yoshida K., Chambers I., Smith A. Complementary tissue-specific expression of LIF and LIF-receptor mRNAs in early mouse embryogenesis. Mech. Dev. 1996, 57:123-131.
323. Lavranos T.C., Rathjen P.D., Seamark R.F. Trophic effects of myeloid leukaemia inhibitory factor (LIF) on mouse embryos. J. Reprod. Fertil. 1995, 105:331-338.
324. Stewart C.L., Kaspar P., Brunet L.J., Bhatt H., Gadi I., Kontgen F., Abbondanzo S.J. Blastocyst implantation depends on maternal expression of leukaemia inhibitory factor. Nature 1992, 359:76-79.
325. O'Neill C. Autocrine mediators are required to act on the embryo by the 2-cell stage to promote normal development and survival of mouse preimplantation embryos in vitro. Biol. Reprod. 1998, 58:1303-1309.
326. Lu D.P., Li Y., Bathgate R., Day M., O'Neill C. Ligand-activated signal transduction in the 2-cell embryo. Biol. Reprod. 2003, 69:106-116.
327. Lu D.P., Chandrakanthan V., Cahana A., Ishii S., O'Neill C. Trophic signals acting via phosphatidylinositol-3 kinase are required for normal preimplantation mouse embryo development. J. Cell. Sci. 2004, 117:1567-1576.
328. Palmieri S.L., Payne J., Stiles C.D., Biggers J.D., Mercola M. Expression of mouse PDGF-A and PDGF alpha-receptor genes during pre- and post-implantation development: evidence for a developmental shift from an autocrine to a paracrine mode of action. Mech. Dev. 1992, 39:181-191.
329. Mummery C.L. Transforming growth factor beta and mouse development. Microsc. Res. Tech. 2001, 52:374-386.
330. Pampfer S., Vanderheyden I., Vesela J., De Hertogh R. Neutralization of tumor necrosis factor alpha (TNF alpha) action on cell proliferation in rat blastocysts by antisense oligodeoxyribonucleotides directed against TNF alpha p60 receptor. Biol. Reprod. 1995, 52:1316-1326.
331. Pampfer S., Wuu Y.D., Vanderheyden I., De Hertogh R. Expression of tumor necrosis factor-alpha (TNF alpha) receptors and selective effect of TNF alpha on the inner cell mass in mouse blastocysts. Endocrinology 1994, 134:206-212.
332. Ware C.B., Horowitz M.C., Renshaw B.R., Hunt J.S., Liggitt D., Koblar S.A., Gliniak B.C., McKenna H.J., Papayannopoulou T., Thoma B., et al. Targeted disruption of the low-affinity leukemia inhibitory factor receptor gene causes placental, skeletal, neural and metabolic defects and results in perinatal death. Development 1995, 121:1283-1299.
333. Luetteke N.C., Qiu T.H., Fenton S.E., Troyer K.L., Riedel R.F., Chang A., Lee D.C. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. Development 1999, 126:2739-2750.
334. Brison D.R., Schultz R.M. Increased incidence of apoptosis in transforming growth factor alpha-deficient mouse blastocysts. Biol. Reprod. 1998, 59:136-144.
335. Kallapur S., Ormsby I., Doetschman T. Strain dependency of TGFbeta1 function during embryogenesis. Mol. Reprod. Dev. 1999, 52:341-349.
336. Roelen B.A., Goumans M.J., Zwijsen A., Mummery C.L. Identification of two distinct functions for TGF-beta in early mouse development. Differentiation 1998, 64:19-31.
337. Zwijsen A., van Rooijen M.A., Goumans M.J., Dewulf N., Bosman E.A., ten Dijke P., Mummery C.L., Huylebroeck D. Expression of the inhibitory Smad7 in early mouse development and upregulation during embryonic vasculogenesis. Dev. Dyn. 2000, 218:663-670.
338. Albano R.M., Groome N., Smith J.C. Activins are expressed in preimplantation mouse embryos and in ES and EC cells and are regulated on their differentiation. Development 1993, 117:711-723.
339. Ducibella T., Ukena T., Karnovsky M., Anderson E. Changes in cell surface and cortical cytoplasmic organization during early embryogenesis in the preimplantation mouse embryo. J. Cell. Biol. 1977, 74:153-167.
340. Vestweber D., Gossler A., Boller K., Kemler R. Expression and distribution of cell adhesion molecule uvomorulin in mouse preimplantation embryos. Dev. Biol. 1987, 124:451-456.
341. Hyafil F., Morello D., Babinet C., Jacob F. A cell surface glycoprotein involved in the compaction of embryonal carcinoma cells and cleavage stage embryos. Cell 1980, 21:927-934.
342. Winkel G.K., Ferguson J.E., Takeichi M., Nuccitelli R. Activation of protein kinase C triggers premature compaction in the four-cell stage mouse embryo. Dev. Biol. 1990, 138:1-15.
343. Larue L., Ohsugi M., Hirchenhain J., Kemler R. E-cadherin null mutant embryos fail to form a trophectoderm epithelium. Proc. Natl. Acad. Sci. USA 1994, 91:8263-8267.
344. Riethmacher D., Brinkmann V., Birchmeier C. A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development. Proc. Natl. Acad. Sci. USA 1995, 92:855-859.
345. Wianny F., Zernicka-Goetz M. Specific interference with gene function by double-stranded RNA in early mouse development. Nat. Cell. Biol. 2000, 2:70-75.
346. Hamatani T., Carter M.G., Sharov A.A., Ko M.S. Dynamics of global gene expression changes during mouse preimplantation development. Dev. Cell. 2004, 6:117-131.
347. Moley K.H., Chi M.M., Mueckler M.M. Maternal hyperglycemia alters glucose transport and utilization in mouse preimplantation embryos. Am. J. Physiol. 1998, 275:E38-E47.
348. Moley K.H. Diabetes and preimplantation events of embryogenesis. Semin. Reprod. Endocrinol. 1999, 17:137-151.
349. Moley K.H., Chi M.M., Knudson C.M., Korsmeyer S.J., Mueckler M.M. Hyperglycemia induces apoptosis in pre-implantation embryos through cell death effector pathways. Nat. Med. 1998, 4:1421-1424.
350. Chi M.M., Pingsterhaus J., Carayannopoulos M., Moley K.H. Decreased glucose transporter expression triggers BAX-dependent apoptosis in the murine blastocyst. J. Biol. Chem. 2000, 275:40252-40257.
351. Heilig C.W., Saunders T., Brosius F.C., Moley K., Heilig K., Baggs R., Guo L., Conner D. Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy. Proc. Natl. Acad. Sci. USA 2003, 100:15613-15618.
352. Pantaleon M., Harvey M.B., Pascoe W.S., James D.E., Kaye P.L. Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst. Proc. Natl. Acad. Sci. USA 1997, 94:3795-3800.
353. Carayannopoulos M.O., Chi M.M., Cui Y., Pingsterhaus J.M., McKnight R.A., Mueckler M., Devaskar S.U., Moley K.H. GLUT8 is a glucose transporter responsible for insulin-stimulated glucose uptake in the blastocyst. Proc. Natl. Acad. Sci. USA 2000, 97:7313-7318.
354. Wyman A.H., Chi M., Riley J., Carayannopoulos M.O., Yang C., Coker K.J., Pessin J.E., Moley K.H. Syntaxin 4 expression affects glucose transporter 8 translocation and embryo survival. Mol. Endocrinol. 2003, 17:2096-2102.
355. Pinto A.B., Carayannopoulos M.O., Hoehn A., Dowd L., Moley K.H. Glucose transporter 8 expression and translocation are critical for murine blastocyst survival. Biol. Reprod. 2002, 66:1729-1733.
356. Kwong W.Y., Wild A.E., Roberts P., Willis A.C., Fleming T.P. Maternal undernutrition during the preimplantation period of rat development causes blastocyst abnormalities and programming of postnatal hypertension. Development 2000, 127:4195-4202.
357. Kim J., Gye M.C., Kim M.K. Role of occludin, a tight junction protein, in blastocoel formation, and in the paracellular permeability and differentiation of trophectoderm in preimplantation mouse embryos. Mol. Cells 2004, 17:248-254.
358. Fleming T.P., McConnell J., Johnson M.H., Stevenson B.R. Development of tight junctions de novo in the mouse early embryo: control of assembly of the tight junction-specific protein, ZO-1. J. Cell. Biol. 1989, 108:1407-1418.
359. Fleming T.P., Hay M., Javed Q., Citi S. Localisation of tight junction protein cingulin is temporally and spatially regulated during early mouse development. Development 1993, 117:1135-1144.
360. Sheth B., Fesenko I., Collins J.E., Moran B., Wild A.E., Anderson J.M., Fleming T.P. Tight junction assembly during mouse blastocyst formation is regulated by late expression of ZO-1 alpha+ isoform. Development 1997, 124:2027-2037.
361. Sheth B., Moran B., Anderson J.M., Fleming T.P. Post-translational control of occludin membrane assembly in mouse trophectoderm: a mechanism to regulate timing of tight junction biogenesis and blastocyst formation. Development 2000, 127:831-840.
362. Fleming T.P., Papenbrock T., Fesenko I., Hausen P., Sheth B. Assembly of tight junctions during early vertebrate development. Semin. Cell. Dev. Biol. 2000, 11:291-299.
363. Robson P., Stein P., Zhou B., Schultz R.M., Baldwin H.S. Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst. Dev. Biol. 2001, 234:317-329.
364. Manejwala F., Kaji E., Schultz R.M. Development of activatable adenylate cyclase in the preimplantation mouse embryo and a role for cyclic AMP in blastocoel formation. Cell 1986, 46:95-103.
365. Manejwala F.M., Cragoe E.J., Schultz R.M. Blastocoel expansion in the preimplantation mouse embryo: role of extracellular sodium and chloride and possible apical routes of their entry. Dev. Biol. 1989, 133:210-220.
366. Wiley L.M. Cavitation in the mouse preimplantation embryo: Na/K-ATPase and the origin of nascent blastocoele fluid. Dev. Biol. 1984, 105:330-342.
367. Watson A.J., Kidder G.M. Immunofluorescence assessment of the timing of appearance and cellular distribution of Na/K-ATPase during mouse embryogenesis. Dev. Biol. 1988, 126:80-90.
368. MacPhee D.J., Jones D.H., Barr K.J., Betts D.H., Watson A.J., Kidder G.M. Differential involvement of Na(+), K(+)-ATPase isozymes in preimplantation development of the mouse. Dev. Biol. 2000, 222:486-498.
369. MacPhee D.J., Barr K.J., De Sousa P.A., Todd S.D., Kidder G.M. Regulation of Na+, K(+)-ATPase alpha subunit gene expression during mouse preimplantation development. Dev. Biol. 1994, 162:259-266.
370. Barcroft L.C., Moseley A.E., Lingrel J.B., Watson A.J. Deletion of the Na/K-ATPase alpha1-subunit gene (Atp1a1) does not prevent cavitation of the preimplantation mouse embryo. Mech. Dev. 2004, 121:417-426.
371. Jones D.H., Davies T.C., Kidder G.M. Embryonic expression of the putative gamma subunit of the sodium pump is required for acquisition of fluid transport capacity during mouse blastocyst development. J. Cell. Biol. 1997, 139:1545-1552.
372. Barr K.J., Garrill A., Jones D.H., Orlowski J., Kidder G.M. Contributions of Na+/H+ exchanger isoforms to preimplantation development of the mouse. Mol. Reprod. Dev. 1998, 50:146-153.
373. Barcroft L.C., Offenberg H., Thomsen P., Watson A.J. Aquaporin proteins in murine trophectoderm mediate transepithelial water movements during cavitation. Dev. Biol. 2003, 256:342-354.
374. Perona R.M., Wassarman P.M. Mouse blastocysts hatch in vitro by using a trypsin-like proteinase associated with cells of mural trophectoderm. Dev. Biol. 1986, 114:42-52.
375. O'Sullivan C.M., Rancourt S.L., Liu S.Y., Rancourt D.E. A novel murine tryptase involved in blastocyst hatching and outgrowth. Reproduction 2001, 122:61-71.
376. Edi-Osagie E., Hooper L., Seif M.W. The impact of assisted hatching on live birth rates and outcomes of assisted conception: a systematic review. Hum. Reprod. 2003, 18:1828-1835.
377. Gardner R.L. The early blastocyst is bilaterally symmetrical and its axis of symmetry is aligned with the animal-vegetal axis of the zygote in the mouse. Development 1997, 124:289-301.
378. Piotrowska K., Zernicka-Goetz M. Role for sperm in spatial patterning of the early mouse embryo. Nature 2001, 409:517-521.
379. Hiiragi T., Solter D. First cleavage plane of the mouse egg is not predetermined but defined by the topology of the two apposing pronuclei. Nature 2004, 403:360-364.
380. Plusa B., Grabarek J.B., Piotrowska K., Glover D.M., Zernicka-Goetz M. Site of the previous meiotic division defines cleavage orientation in the mouse embryo. Nat. Cell. Biol. 2002, 4:811-815.
381. Piotrowska K., Wianny F., Pedersen R.A., Zernicka-Goetz M. Blastomeres arising from the first cleavage division have distinguishable fates in normal mouse development. Development 2001, 128:3739-3748.
382. Weber R.J., Pedersen R.A., Wianny F., Evans M.J., Zernicka-Goetz M. Polarity of the mouse embryo is anticipated before implantation. Development 1999, 126:5591-5598.
383. Geijsen N., Horoschak M., Kim K., Gribnau J., Eggan K., Daley G.Q. Derivation of embryonic germ cells and male gametes from embryonic stem cells. Nature 2004, 427:148-154.
384. Toyooka Y., Tsunekawa N., Akasu R., Noce T. Embryonic stem cells can form germ cells in vitro. Proc. Natl. Acad. Sci. USA 2003, 100:11457-11462.
385. Hubner K., Fuhrmann G., christenson L.K., Kehler J., Reinbold R., De La Fuente R., Wood J., Strauss J.F., Boiani M., Scholer H.R. Derivation of oocytes from mouse embryonic stem cells. Science 2003, 300:1251-1256.
386. Latham K.E. Cloning: questions answered and unsolved. Differentiation 2004, 72:11-22.
387. Mitsui K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., Maruyama M., Maeda M., Yamanaka S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113:631-642.
388. Tanaka T.S., Kunath T., Kimber W.L., Jaradat S.A., Stagg C.A., Usuda M., Yokota T., Niwa H., Rossant J., Ko M.S. Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res. 2002, 12:1921-1928.
389. Fan Y., Melhem M.F., Chaillet J.R. Forced expression of the homeobox-containing gene Pem blocks differentiation of embryonic stem cells. Dev. Biol. 1999, 210:481-496.
390. Fujikura J., Yamato E., Yonemura S., Hosoda K., Masui S., Nakao K., Miyazaki, Ji J., Niwa H. Differentiation of embryonic stem cells is induced by GATA factors. Genes Dev. 2002, 16:784-789.
391. Smith A.G. Embryo-derived stem cells: of mice and men. Annu. Rev. Cell. Dev. Biol. 2001, 17:435-462.
392. Niwa H., Burdon T., Chambers I., Smith A. Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3. Genes Dev. 1998, 12:2048-2060.
393. Matsuda T., Nakamura T., Nakao K., Arai T., Katsuki M., Heike T., Yokota T. STAT3 activation is sufficient to maintain an undifferentiated state of mouse embryonic stem cells. EMBO J. 1999, 18:4261-4269.
394. Raz R., Lee C.K., Cannizzaro L.A., d'Eustachio P., Levy D.E. Essential role of STAT3 for embryonic stem cell pluripotency. Proc. Natl. Acad. Sci. USA 1999, 96:2846-2851.
395. Takeda K., Noguchi K., Shi W., Tanaka T., Matsumoto M., Yoshida N., Kishimoto T., Akira S. Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality. Proc. Natl. Acad. Sci. USA 1997, 94:3801-3804.
396. Yoshida K., Taga T., Saito M., Suematsu S., Kumanogoh A., Tanaka T., Fujiwara H., Hirata M., Yamagami T., Nakahata T., Hirabayashi T., Yoneda Y., Tanaka K., Wang W.Z., Mori C., Shiota K., Yoshida N., Kishimoto T. Targeted disruption of gp130, a common signal transducer for the interleukin 6 family of cytokines, leads to myocardial and hematological disorders. Proc. Natl. Acad. Sci. USA 1996, 93:407-411.
397. Benezra R., Davis R.L., Lockshon D., Turner D.L., Weintraub H. The protein Id: a negative regulator of helix-loop-helix DNA binding proteins. Cell 1990, 61:49-59.
398. Ying Q.L., Nichols J., Chambers I., Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell 2003, 115:281-292.
399. Nakashima K., Yanagisawa M., Arakawa H., Kimura N., Hisatsune T., Kawabata M., Miyazono K., Taga T. Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300. Science 1999, 284:479-482.
400. Okamoto K., Okazawa H., Okuda A., Sakai M., Muramatsu M., Hamada H. A novel octamer binding transcription factor is differentially expressed in mouse embryonic cells. Cell 1990, 60:461-472.
401. Nichols J., Zevnik B., Anastassiadis K., Niwa H., Klewe-Nebenius D., Chambers I., Scholer H., Smith A. Formation of pluripotent stem cells in the mammalian embryo depends on the POU transcription factor Oct4. Cell 1998, 95:379-391.
402. Niwa H., Miyazaki J., Smith A.G. Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-rennewal of ES cells. Nat. Genet. 2000, 24:372-376.
403. Niwa H. Molecular mechanism to maintain stem cell renewal of ES cells. Cell. Struct. Funct. 2001, 26:137-148.
404. Remenyi A., Lins K., Nissen L.J., Reinbold R., Scholer H.R., Wilmanns M. Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev. 2003, 17:2048-2059.
405. Kuroda T., Tada M., Kubota H., Kimura H., Hatano S.Y., Suemori H., Nakatsuji N., Tada T. Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression. Mol. Cell Biol. 2005, 25(6):2475-2485.
406. Rodda D.J., Chew J.L., Lim L.H., Loh Y.H., Wang B., Ng H.H., Robson P. Transcriptional regulation of nanog by OCT4 and SOX2. J. Biol. Chem. 2005, (epub).
407. Avilion A.A., Nicolis S.K., Pevny L.H., Perez L., Vivian N., Lovell-Badge R. Multipotent cell lineages in early mouse development depend on SOX2 function. Genes Dev. 2003, 17:126-140.
408. Hanna L.A., Foreman R.K., Tarasenko I.A., Kessler D.S., Labosky P.A. Requirement for Foxd3 in maintaining pluripotent cells of the early mouse embryo. Genes Dev. 2002, 16:2650-2661.
409. Guo Y., Costa R., Ramsey H., Starnes T., Vance G., Robertson K., Kelley M., Reinhold R., Scholer H., Hromas R. The embryonic stem cell transcription factors Oct-4 and FoxD3 interact to regulate endodermal-specific promoter expression. Proc. Natl. Acad. Sci USA 2002, 99:3663-3667.
410. Chambers I., Colby D., Robertson M., Nichols J., Lee S., Tweedie S., Smith A. Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells. Cell 2003, 113:643-655.
411. Wang S.H., Tsai M.S., Chiang M.F., Li H. A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells. Gene Expr. Patterns. 2003, 3:99-103.
412. Zheng P., Patel B., McMenamin M., Reddy S.E., Paprocki A.M., Schramm R.D., Latham K.E. The primate embryo gene expression resource: a novel resource to facilitate rapid analysis of gene expression patterns in non-human primate oocytes and preimplantation stage embryos. Biol. Reprod. 2004.
413. De Rycke M., Liebaers I., Van Steirteghem A. Epigenetic risks related to assisted reproductive technologies: risk analysis and epigenetic inheritance. Hum. Reprod. 2002, 17:2487-2494.
414. Humpherys D., Eggan K., Akutsu H., Hochedlinger K., Rideout W.M., Biniszkiewicz D., Yanagimachi R., Jaenisch R. Epigenetic instability in ES cells and cloned mice. Science 2001, 293:95-97.
415. Kono T., Obata Y., Wu Q., Niwa K., Ono Y., Yamamoto Y., Park E.S., Seo J.S., Ogawa H. Birth of parthenogenetic mice that can develop to adulthood. Nature 2004, 428:860-864.
416. Hwang W.S., Ryu Y.J., Park J.H., Park E.S., Lee E.G., Koo J.M., Chun H.Y., Lee B.C., Kang S.K., Kim S.J., Ahn C., Hwang J.H., Park K.Y., Cibelli J.B., Moon S.Y. Evidence of a pluripotent human embryonic stem cell line derived from a cloned blastocyst. Science 2004.
417. Chang H.Y., Yang X. Proteases for cell suicide: functions and regulation of caspases. Microbiol. Mol. Biol. Rev. 2000, 64:821-846.
418. Chang H., Brown C.W., Matzuk M.M. Genetic analysis of the mammalian TGF-b superfamily. Endocrine Reviews 2002, 23:787-823.
419. Antczak M., Van Blerkom J. Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol. Hum. Reprod. 1997, 3.