Stabilization of Xist RNA mediates initiation of X chromosome inactivation

Cell

Volumn 91, Issue 1, 1997, Pages 99-107

  Sheardown, Steven A ^a,b   Duthie, Sarah M ^a   Johnston, Colette M ^a   Newall, Alistair E T ^a   Formstone, Emma J ^a   Arkell, Ruth M ^a   Nesterova, Tatyana B ^a   Alghisi, Gian Carlo ^a   Rastan, Sohaila ^a,b   Brockdorff, Neil ^a  

^a MRC CLINICAL SCIENCES CENTRE   (United Kingdom)

^b GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CHROMOSOME INACTIVATION; EARLY DIAGNOSIS; EMBRYO DEVELOPMENT; FEMALE; GENE CONTROL; GENETIC STABILITY; MALE; MOLECULAR CLONING; NONHUMAN; PRIORITY JOURNAL; STEADY STATE; X CHROMOSOME ABERRATION;

ANIMALIA;

EID: 18844472627     PISSN: 00928674     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0092-8674(01)80012-X     Document Type: Article

References (52)

1. Beard, C., Li, E., and Jaenisch, R. (1995). Loss of methylation activates Xist in somatic but not in embryonic cells. Genes Dev. 9, 2325-2334.
2. Beddington, R.S.P. (1987). Isolation, culture and manipulation of postimplantation mouse embryos. In Mammalian Development: A Practical Approach M. Monk, ed. (Oxford: IRL Press), 43-69.
3. Borsani, G., Tonlorenzi, R., Simmler, M.C., Dandolo, L., Arnaud, D., Capra, V., Grompe, M., Pizzuti, A., Muzny, D., Lawrence, C., et al. (1991). Characterization of a murine gene expressed from the inactive X chromosome. Nature 351, 325-329.
4. Brockdorff, N., Ashworth, A., Kay, G.F., Cooper, P., Smith, S., McCabe, V.M., Norris, D.P., Penny, G.D., Patel, D., and Rastan, S. (1991). Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome. Nature 351, 329-331.
5. Brockdorff, N., Ashworth, A., Kay, G.F., McCabe, V.M., Norris, D.P., Cooper, P.J., Swift, S., and Rastan, S. (1992). The product of the mouse Xist gene is a 15 kb inactive X-specific transcript containing no conserved ORF and located in the nucleus. Cell 71, 515-526.
6. Brown, C.J., and Willard, H.F. (1994). The human X-inactivation center is not required for maintenance of X-chromosome inactivation. Nature 368, 154-156.
7. Brown, C.J., Ballabio, A., Rupert, J.L., Lafreniere, R.G., Grompe, M., Tonlorenzi, R., and Willard, H.F. (1991a). A gene from the region of the human X inactivation centre is expressed exclusively from the inactive X chromosome. Nature 349, 38-44.
8. Brown, C.J., Lafreniere, R.G., Powers, V.E., Sebastio, G., Ballabio, A., Pettigrew, A.L., Ledbetter, D.H., Levy, E., Craig, I.W., and Willard, H.F. (1991b). Localization of the X inactivation centre on the human X chromosome in Xq13. Nature 349, 82-84.
9. Brown, C.J., Hendrich, B.D., Rupert, J.L., Lafreniere, R.G., Xing, Y., Lawrence, J., and Willard, H.F. (1992). The human Xist gene: analysis of a 17 kb inactive X-specific RNA that contains conserved repeats and is highly localized within the nucleus. Cell 71, 527-542.
10. Buzin, C.H., Mann, J.R., and Singersam, J. (1994). Quantitative RT-PCR assays show Xist RNA levels are low in mouse female adult tissue, embryos and embryoid bodies. Development 120, 3529-3536.
11. Cattanach, B.M., and Papworth, D. (1981). Controlling elements in the mouse V. Linkage tests with X-linked genes. Genet. Res. 38, 57-70.
12. Cattanach, B.M., Pollard, C.E., and Perez, J.N. (1969). Controlling elements in the mouse X-chromosome I. Interaction with the X-linked genes. Genet. Res. 14, 223-235.
13. Chew, L.J., Murphy, D., and Carter, D.A. (1994). Alternatively polyadenylated vasoactive intestinal peptide mRNAs are differentially regulated at the level of stability. Mol. Endocrinol. 8, 603-613.
14. Clemson, C.M., Mcneil, J.A., Willard, H.F., and Lawrence, J.B. (1996). XISTRNA paints the inactive Xchromosome at interphase: evidence for a novel RNA involved in nuclear chromosome structure. J. Cell. Biol. 132, 259-275.
15. Drews, U., Blechler, S., Owen, D.A., and Ohno, S. (1974) Genetically directed preferential X-Activation seen in mice. Cell 1, 3-8.
16. Epstein, C.J., Smith, S., Travis, B., and Tucker, G. (1978). Both X chromosomes function before visible X-chromosome inactivation in female mouse embryos. Nature 274, 500-502.
17. Grumbach, M.M., Morishima, A., and Taylor, J.H. (1963). Human sex chromosome abnormalities in relation to DNA replication and heterochromatinization. Proc. Natl. Acad. Sci. USA 49, 581-589.
18. Hendrich, B.D., Plenge, R., and Willard, H.F. (1997). Identification and characterization of the human XIST promoter: implications for models of X chromosome inactivation. Nucleic Acids Res. 25, 2661-2671.
19. Herzing, L.B.K., Romer, J.T., Horn, J.M., and Ashworth, A. (1997). Xist has properties of the X chromosome inactivation center. Nature 386, 272-275.
20. Hogan, B., Beddington, R., Constantini, F., and Lacy, E. (1994). Manipulating the Mouse Embryo: A Laboratory Manual. (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press).
21. Jeppesen, P., and Turner, B.M. (1993).The inactive X chromosome in female mammals is distinguished by a lack of histone H4 acetylation, a cytogenetic marker for gene expression. Cell 74, 281-289.
22. Johnston, P.G., and Cattanach, B.M. (1981). Controlling elements in the mouse IV. Evidence of nonrandom X-inactivation. Genet. Res. 37, 151-160.
23. Kay, G.F., Penny, G.D., Patel, D., Ashworth, A., Brockdorff, N., and Rastan, S. (1993). Expression of Xist during mouse development suggests a role in the initiation of X chromosome inactivation. Cell 72, 171-182.
24. Kay, G.F., Barton, S.C., Surani, M.A., and Rastan, S. (1994). Imprinting and X chromosome counting mechanisms determine Xist expression in early mouse development. Cell 77, 639-650.
25. Keohane, A.M., Belyaev, N.D., Lavender, J.S., O'Neill, L.P., and Turner, B.M. (1996). X-inactivation and histone H4 acetylation in embryonic stem cells. Dev. Biol. 180, 618-630.
26. Lee, J.T., and Jaenisch, R. (1997). Long range cis effects of ectopic X inactivation centers on a mouse autosome. Nature 386, 275-279.
27. Lee, J.T., Strauss, W.M., Dausman, J.A., and Jaenisch, R. (1996). A 450 kb transgene displays properties of the mammalian X inactivation center. Cell 86, 83-94.
28. Lyon, M.F. (1961) Gene action in the X chromosome of the mouse (Mus musculus L). Nature 190, 372-373.
29. Marahrens, Y., Panning, B., Dausman, J., Strauss, W., and Jaenisch, R. (1997). Xist deficient mice are defective in dosage compensation but not spermatogenesis. Genes Dev. 11, 156-166.
30. Martin, G.R., Epstein, C.J., Travis, B., Tucker, G., Yatziv, S., Martin, D.W., Jr., Clift, S., and Cohen, S. (1978). X-chromosome inactivation during differentiation of female teratocarcinoma stem cells in vitro. Nature 271, 329-333.
31. McBurney, M.W., and Strutt, B.J. (1980). Genetic activity of X chromosomes in pluripotent female teratocarcinoma cells and their differentiated progeny. Cell 21, 357-364.
32. McMahon, A., Fosten, M., and Monk, M. (1983). X-chromosome inactivation mosaicism in the three germ layers and the germ line of the mouse embryo. J. Embryol. Exp. Morph. 74, 207-220.
33. Monk, M., and Harper, M.I. (1979). Sequential X chromosome inactivation coupled with cellular differentiation in early mouse embryos. Nature 281, 311-313.
34. Norris, D.P., Patel, D., Kay, G.F., Penny, G.D., Brockdorff, N., Sheardown, S.A., and Rastan, S. (1994). Evidence that random and imprinted Xist expression is controlled by preemptive methylation. Cell 77, 41-51.
35. Panning, B., and Jaenisch, R., (1996). DNA hypomethylation can activate Xist expression and silence X linked genes. Genes Dev. 10, 1991-2002.
36. Penny, G.D., Kay, G.F., Sheardown, S.A., Rastan, S., and Brockdorff, N. (1996). Requirement for Xist in X chromosome inactivation. Nature 379, 131-137.
37. Rack, K.A., Chelly, J., Gibbons, R.J., Rider, S., Benjamin, D., Lafreniere, R.G., Oscier, D., Hendriks, R.W., Craig, I.W., Willard, H.F. et al. (1994). Absence of the XIST gene from late-replicating isodicentric X chromosomes in leukaemia. Hum. Mol. Genet. 3, 1053-1059.
38. Rastan, S. (1982a). Primary nonrandom X-inactivation caused by controlling elements in the mouse demonstrated at the cellular level. Genet. Res. 40, 139-147.
39. Rastan, S. (1982b). Timing of X-chromosome inactivation in postimplantation mouse embryos. J. Embryol. Exp. Morphol. 71, 11-24.
40. Rastan, S. (1983). Nonrandom X-chromosome inactivation in mouse X-autosome translocation embryos - location of the inactivation centre. J. Embryol. Exp. Morphol. 78, 1-22.
41. Rastan, S., and Brown, S.D. (1990). The search for the mouse X-chromosome inactivation center. Genet. Res. 56, 99-106.
42. Rastan, S., and Robertson, E.J. (1985). X-chromosome deletions in embryo-derived (EK) cell lines associated with lack of X-chromosome inactivation. J. Embryol. Exp. Morphol. 90, 379-388.
43. Ross, J. (1996). Control of messenger RNA stability in higher eukaryotes. Trends Genet. 12, 171-175.
44. Russell, L.B., and Mongomery, C.S. (1965). The use of X-autosome translocations in locating the X-chromosome inactivation center. Genetics 52, 470-471.
45. Sachs, A.B. (1993). Messenger RNA degradation in eukaryotes. Cell 74, 413-421.
46. Simmler, M.C., Cattanach, B.M., Rasberry, C., Rougeulle, C., and Avner, P. (1993). Mapping the murine Xce locus with (CA)n repeats. Mamm. Genome 4, 523-530.
47. Simmler, M.C., Cunningham, D.B., Clerc, P., Vermat, T., Caudron, B., Cruaud, C., Pawlak, A., Szpirer, C., Weissenbach, J., Claverie, J.M., and Avner, P. (1996). A 94 kb genomic sequence 3′ to the murine Xist gene reveals an at rich region containing a new testis specific gene Tsx. Hum. Mol. Genet. 5, 1713-1726.
48. Sheardown, S.A., Newall, A.E.T., Norris, D.P., Rastan, S., and Brockdorff, N. (1997). Regulatory elements in the minimal promoter region of the mouse Xist gene. Gene, in press.
49. Takagi, N., and Sasaki, M. (1975). Preferential inactivation of the paternally derived X chromosome in the extraembryonic membranes of the mouse. Nature 256, 640-642.
50. Takagi, N., Sugawara, O., and Sasaki, M. (1982). Regional and temporal changes in the pattern of X-chromosome replication during the early postimplantation development of the female mouse. Chromosoma 85, 275-286.
51. Webb, S., de Vries, T.J., and Kaufman, M.H. (1992). The differential staining pattern of the X chromosome in the embryonic and extraembryonic tissues of postimplantation homozygous tetraploid mouse embryos. Genet. Res. 59, 205-214.
52. Wijgerde, M., Grosveld, F., and Fraser, P. (1995). Transcription complex stability and chromatin dynamics in vivo. Nature 377, 209-213.