Synergistic signaling in fetal brain by STAT3-Smad1 complex bridged by p300

Science

Volumn 284, Issue 5413, 1999, Pages 479-482

  Nakashima, Kinichi ^a   Yanagisawa, Makoto ^a   Arakawa, Hirokazu ^a   Kimura, Naoki ^a   Hisatsune, Tatsuhiro ^a   Kawabata, Masahiro ^a   Miyazono, Kohei ^a   Taga, Tetsuya ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; CYTOKINE; LEUKEMIA INHIBITORY FACTOR; STAT3 PROTEIN;

ARTICLE; ASTROCYTE; CELL ACTIVATION; COMPLEX FORMATION; FETUS; FETUS (ANATOMY); HUMAN; HUMAN TISSUE; NERVE CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; ASTROCYTES; BONE MORPHOGENETIC PROTEIN RECEPTORS; BONE MORPHOGENETIC PROTEINS; CELL DIFFERENTIATION; CELL NUCLEUS; CELLS, CULTURED; COS CELLS; CYTOKINES; DNA-BINDING PROTEINS; E1A-ASSOCIATED P300 PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; GROWTH INHIBITORS; INTERLEUKIN-6; LEUKEMIA INHIBITORY FACTOR; LEUKEMIA INHIBITORY FACTOR RECEPTOR ALPHA SUBUNIT; LYMPHOKINES; MICE; NUCLEAR PROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, CELL SURFACE; RECEPTORS, CYTOKINE; RECEPTORS, GROWTH FACTOR; RECEPTORS, OSM-LIF; SEQUENCE DELETION; SIGNAL TRANSDUCTION; SMAD PROTEINS; SMAD1 PROTEIN; STAT3 TRANSCRIPTION FACTOR; STEM CELLS; TELENCEPHALON; TRANS-ACTIVATION (GENETICS); TRANS-ACTIVATORS; TRANSFORMING GROWTH FACTOR BETA;

EID: 0033574767     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.284.5413.479     Document Type: Article

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36. We thank R. Eckner for HA-p300, M. Minami and S. Akira for DN-STAT3, K. Shimozaki and S. Nagata for pEF-BOS and R-Luc, K. Ikenaka for GFAP gene promoter, K. Yasukawa for sIL-6R, Genetics Institute for BMP2 and BMP4, A. Nishihara for p300 deletion constructs, J. Akai and R. Hata for help and discussion on luciferase assays, and T. Imamura for valuable discussion, We also thank Y. Nakamura for secretarial assistance and K. Saito for technical help. Supported by a grant-in-aid from the Ministry of Education, Science, Sports and Culture of Japan and by the Human Frontier Science Program, Cell Science Research Foundation, and Kowa Life Science Foundation.