Cdc25b phosphatase is required for resumption of meiosis during oocyte maturation

Nature Genetics

Volumn 30, Issue 4, 2002, Pages 446-449

  Lincoln, A Jeannine ^a,c   Wickramasinghe, Dineli ^a,d   Stein, Paula ^b   Schultz, Richard M ^b   Palko, Mary Ellen ^a   De Miguel, Maria P ^a,c   Tessarollo, Lino ^a   Donovan, Peter J ^a,c  

^a NATIONAL CANCER INSTITUTE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c THOMAS JEFFERSON UNIVERSITY   (United States)

^d GENENTECH INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 1; DNA; MESSENGER RNA; PHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; FIBROBLAST; MEIOSIS; MITOSIS; MOUSE; NONHUMAN; OOCYTE MATURATION; PRIORITY JOURNAL;

ANIMALS; BLOTTING, SOUTHERN; BLOTTING, WESTERN; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELLS, CULTURED; DNA DAMAGE; FEMALE; MALE; MAP KINASE SIGNALING SYSTEM; MEIOSIS; MICE; MICROSCOPY, FLUORESCENCE; MITOSIS; MODELS, GENETIC; OOCYTES; RNA, MESSENGER;

ANIMALIA; VERTEBRATA;

EID: 0036544855     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng856     Document Type: Article

References (26)

1. Oocyte maturation
2. Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+
3. The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis
4. Human homolog of fission yeast cdc25 mitotic inducer is predominantly expressed in G2
5. An additional homolog of the fission yeast cdc25+ gene occurs in humans and is highly expressed in some cancer cells
6. Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins
7. A mouse cdc25 homolog is differentially and developmentally expressed
8. Cdc25M2 activation of cyclin-dependent kinases by dephosphorylation of threonine-14 and tyrosine-15
9. Function and regulation of cdc25 protein phosphate through mitosis and meiosis
10. Checkpoint pathways come of age
11. A DNA damage checkpoint meets the cell cycle engine
12. Cdc25 protein phosphatases in cell proliferation
13. Targeted mutation in the neurotrophin-3 gene results in loss of muscle sensory neurons
14. Meiotic competence acquisition is associated with the appearance of M-phase characteristics in growing mouse oocytes
15. Two CDC25 homologues are differentially expressed during mouse development
16. Cloning and characterization of a cdc25 phosphatase from mouse lymphocytes
17. The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis
18. Regulation of the acquisition of meiotic competence in the mouse: Changes in the subcellular localization of cdc2, cyclin B1, cdc25c and wee1, and in the concentration of these proteins and their transcripts
19. Tyrosine phosphorylation of the fission yeast cdc2+ protein kinase regulates entry into mitosis
20. The cdc25 protein controls tyrosine dephosphorylation of the cdc2 protein in a cell-free system
21. The cdc25 protein contains an intrinsic phosphatase activity
22. Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein
23. Cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2
24. Absence of apparent phenotype in mice lacking Cdc25c protein phosphatase
25. A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators
26. Selective reduction of dormant maternal mRNAs in mouse oocytes by RNA interference